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Malformations of cerebral development and clues from the peripheral nervous system: A systematic literature review.

Eur J Paediatr Neurol 2021 Aug 31. Epub 2021 Aug 31.

Neurogenetics Research Group, Vrije Universiteit Brussel, Brussels, Belgium; Department of Pathology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium. Electronic address:

Clinical manifestations of malformations of cortical development (MCD) are variable and can range from mild to severe intellectual disability, cerebral palsy and drug-resistant epilepsy. Besides common clinical features, non-specific or more subtle clinical symptoms may be present in association with different types of MCD. Especially in severely affected individuals, subtle but specific underlying clinical symptoms can be overlooked or overshadowed by the global clinical presentation. Read More

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The Influence of White Matter Hyperintensities and Functional Connectivity on Cognition in Older Adults: A Commentary on Jaywant et al.

Authors:
Julie A Dumas

Am J Geriatr Psychiatry 2021 Aug 21. Epub 2021 Aug 21.

Department of Psychiatry, Larner College of Medicine (JAD), University of Vermont, Burlington, VT. Electronic address:

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Role of Neonatal Behavioral Neurological Assessment combined with magnetic resonance diffusion tensor imaging in evaluating white matter development in preterm infants.

Zhongguo Dang Dai Er Ke Za Zhi 2021 Sept 15;23(9):916-921

Department of Neonatology, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China (Xu F-L, Email: com).

Objectives: To study the correlation of fractional anisotropy (FA) on magnetic resonance diffusion tensor imaging with Neonatal Behavioral Neurological Assessment (NBNA) score in preterm infants, and to study the role of FA in evaluating white matter development from the perspective of imaging.

Methods: A prospective study was performed for 98 preterm infants who were admitted to the Neonatal Intensive Care Unit of the Third Affiliated Hospital of Zhengzhou University within 24 hours after birth from October 2016 to January 2020. According to the results of NBNA, they were divided into an abnormal group with 51 infants (NBNA score <37) and a normal group with 47 infants (NBNA score ≥37). Read More

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September 2021

Dimerization in α-TiCl3 and α-TiBr3: The DFT study.

J Phys Condens Matter 2021 Sep 17. Epub 2021 Sep 17.

Ural Branch RAS, Russian Academy of Sciences - Institute of Metal Physics, Kovalevskaya st., 18,, Ekaterinburg, RUSSIA, Ekaterinburg, 620137, RUSSIAN FEDERATION.

A series of DFT calculations for two layered compounds with honeycomb lattice - α-TiCl3 and α-TiBr3 has been performed. It was shown that the symmetric SU(4) spin-orbital model recently proposed for d1 systems with honeycomb lattice can not be realized in these titanates because they dimerize in the low temperature phase. This explains experimentally observed drop in magnetic susceptibility of α-TiBr3. Read More

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September 2021

Electron Spin Resonance of the itinerant ferromagnets LaCrGe, CeCrGeand PrCrGe.

J Phys Condens Matter 2021 Sep 17. Epub 2021 Sep 17.

Department of Physics, Indian Institute of Technology Kanpur, Kalyanpur, Kanpur, Uttar Pradesh, 208016, INDIA.

We report Electron Spin Resonance of the itinerant ferromagnets LaCrGe3, CeCrGe3, and PrCrGe3. These compounds show well defined and very similar spectra of itinerant Cr 3d spins in the paramagnetic temperature region. Upon cooling and crossing the Cr-ferromagnetic ordering (below around 90 K) strong spectral structures start to dominate the resonance spectra in a quite different manner in the three compounds. Read More

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September 2021

Recent advances in topological elastic metamaterials.

J Phys Condens Matter 2021 Sep 17. Epub 2021 Sep 17.

Hunan University, Hunan University, Changsha, Hunan, 410082, CHINA.

Topological elastic metamaterials have emerged as a new frontier in the quest of topological phases in condensed matter physics. Their exotic topological properties open a wealth of promising engineering-oriented applications that are difficult to realize with traditional elastic metamaterials, such as robust and defect insensitive waveguiding, signal sensing, and splitting. In this review, we retrospectively examine the underlying physical concept of topologically ordered states of elastic waves, starting from the one-dimensional (1D) example based on the Su-Schrieffer-Heeger (SSH) model. Read More

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September 2021

Regular magnetic orders in triangular and kagome lattices.

J Phys Condens Matter 2021 Sep 17. Epub 2021 Sep 17.

Indian Institute of Technology Guwahati, Dept. of physics , Indian Institute of Technology Guwahati, Guwahati, Assam, India 781039, Guwahati, Assam, 781039, INDIA.

We investigate the possible regular magnetic order (RMO) for the spin models with global O(3) spin rotation, based on a group theoretical approach for triangular and kagome lattices. The main reason to study these RMOs is that they are good variational candidates for the ground states of many specific models. In this work, we followed the prescription introduced by Messio et al. Read More

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September 2021

Enhanced nitrogen removal by partial nitrification-anammox process with a novel high-frequency micro-aeration (HFMA) mode: Metabolic interactions among functional bacteria.

Bioresour Technol 2021 Sep 8;342:125917. Epub 2021 Sep 8.

School of Human Settlements and Civil Engineering, Xi'an Jiaotong University, Xi'an, Shaanxi Province 710049, China; School of Environmental and Municipal Engineering, Xi'an University of Architecture and Technology, Xi'an, Shaanxi Province 710055, China.

A novel high-frequency micro-aeration (HFMA) mode with aeration frequency of 15 times/h and DO concentration lower than 0.5 mg/L was proposed. Advanced partial nitrification-anammox (PN-A) performance was achieved in a two-stage sequencing batch reactor-integrated fixed-film activated sludge reactor with the HFMA mode. Read More

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September 2021

Biophysical matter in a marine estuary identified by the Sentinel-3B OLCI satellite and the presence of terrestrial iron (Fe) nanoparticles.

Mar Pollut Bull 2021 Sep 14;173(Pt A):112925. Epub 2021 Sep 14.

Department of Civil and Environmental, Universidad de la Costa, CUC, Calle 58 # 55-66, Barranquilla, Atlántico, Colombia. Electronic address:

The analysis of marine matter using the Sentinel-3B OLCI (Ocean Land Color Instrument) satellite is the most advanced technique for evaluating: the absorption of colored detrital and dissolved material (ADG_443_NN), total suspended matter concentration (TSM_NN) and of chlorophyll-a (CHL_NN) on a global scale. The objective is to analyze ADG_443_NN, TSM_NN and CHL_NN using the Sentinel-3B OLCI satellite and the presence of Fe-nanoparticles (NPs) + hazardous elements (HEs) in suspended sediments (SSs) in the maritime estuary of the Colombian city of Barranquilla. The study used the unpublished image of the Sentinel-3B OLCI satellite in the evaluation of ADG_443_NN, TSM_NN and CHL_NN in 72 sampled points. Read More

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September 2021

Single-subject gray matter networks in temporal lobe epilepsy patients with hippocampal sclerosis.

Epilepsy Res 2021 Sep 13;177:106766. Epub 2021 Sep 13.

Department of Radiology, National Center Hospital, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-Higashi, Kodaira, Tokyo, 187-8551, Japan; Cyclotron and Drug Discovery Research Center, Southern TOHOKU Research Institute for Neuroscience, Koriyama, Fukushima, 963-8052, Japan. Electronic address:

Objective: Previous studies have demonstrated structural brain network abnormalities in patients with temporal lobe epilepsy (TLE) using cortical thickness or gray matter (GM) volume. However, no studies have applied single-subject GM network analysis. Here, we first applied an analysis of similarity-based single-subject GM networks to individual patients with TLE. Read More

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September 2021

Does the gut microbiome partially mediate the impact of air pollutants exposure on liver function? Evidence based on schizophrenia patients.

Environ Pollut 2021 Sep 11;291:118135. Epub 2021 Sep 11.

Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, China. Electronic address:

Air pollution may alter the composition of gut microbiome and subsequent liver-related metabolic disorders. Schizophrenia was often accompanied by liver dysfunction. But it was still unclear whether air pollutants affected liver function in patients with schizophrenia through gut microbiome. Read More

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September 2021

Fatty acid profile as an efficient bioindicator of PCB bioaccumulation in a freshwater lake food web: A stable isotope guided investigation.

J Hazard Mater 2021 Sep 6;423(Pt B):127121. Epub 2021 Sep 6.

National Engineering Laboratory for Lake Pollution Control and Ecological Restoration, State Environmental Protection Scientific Observation and Research Station for Lake Dongtinghu, Chinese Research Academy of Environmental Sciences, Beijing 100012, China. Electronic address:

In past studies, the health and ecological risks of PCBs are well established. The impact of low-dose PCBs on aquatic ecosystems for an extended period is a matter of concern in the current era. The application of fatty acids (FAs) as bioindicators of pollution in the freshwater food web is almost unavailable. Read More

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September 2021

Exposure to black carbon is associated with symptoms of depression: A retrospective cohort study in college students.

Environ Int 2021 Sep 14;157:106870. Epub 2021 Sep 14.

Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Central South University, Changsha, China. Electronic address:

Background: Previous studies have revealed a significant association of fine particulate matter (PM) with emotional disorders. However, as a crucial component of PM, little is known about the potential effect of exposure to black carbon (BC) on the symptoms of depression and anxiety.

Objectives: To explore the associations of long-term exposure to BC during the past six years with the current symptoms of depression and anxiety in a group of incoming college students. Read More

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September 2021

Amorphous cobalt oxide decorated halloysite nanotubes for efficient sulfamethoxazole degradation activated by peroxymonosulfate.

J Colloid Interface Sci 2021 Sep 9;607(Pt 1):857-868. Epub 2021 Sep 9.

School of Environmental Science and Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China; Institute for Ecological Research and Pollution Control of Plateau Lakes, Institute of International Rivers and Eco-Security, School of Ecology and Environmental Science, Yunnan University, Kunming 650504, China. Electronic address:

In this study, a new hollow nanotube material, 30% Co-CHNTs was prepared by the impregnation-chemical reduction-calcination method. This material can be used as a peroxymonosulfate (PMS) activator to catalyse the degradation of sulfamethoxazole (SMX). The best reaction conditions that correspond to the degradation rate of SMX, up to 97. Read More

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September 2021

Dietary watermelon residue influencing the nonspecific immunity of juvenile Pseudorasbora parva.

Fish Shellfish Immunol 2021 Sep 14. Epub 2021 Sep 14.

College of Architectural Engineering, Weifang University, Weifang, 261061, China; College of Natural Resources and Environment, South China Agricultural University, Guangzhou, 510642, China. Electronic address:

The study explored the improvement of disease resistance, non-specific immunity and anti-oxidation reactions for Pseudorasbora parva (PP) using dietary watermelon residue. The cumulative PP mortality and the pathogenic bacteria number in 15-45% groups reduced relative to those in control group (CK). Under 15-45% groups, AKP, ACP activities and akp, acp genes expression levels were increased markedly in nonspecific immunity system. Read More

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September 2021

In vitro efficacy of different concentrations of Duddingtonia flagrans on varying egg densities of gastrointestinal nematodes of cattle.

Exp Parasitol 2021 Sep 14:108156. Epub 2021 Sep 14.

Área de Parasitología y Enfermedades Parasitarias, Centro de Investigación Veterinaria de Tandil (CIVETAN) (CONICET-UNCPBA-CICPBA), Facultad de Ciencias Veterinarias, UNCPBA, Tandil, Argentina.

The nematophagous fungus Duddingtonia flagrans, used for the biological control of gastrointestinal nematodes in livestock, is fed to infected animals so its chlamydospores and the parasite eggs are voided together with faeces where the fungus preys on nematode larvae, thus reducing pasture infectivity. The number of chlamydospores needed for the fungus to be efficient in the presence of a wide range in numbers of parasitic eggs is largely unknown and a matter of discussion. The aim of this study was to determine the fungal efficacy of four different chlamydospore concentrations against three different levels of cattle faecal egg counts. Read More

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September 2021

Ambient air pollution and COVID-19 risk: Evidence from 35 observational studies.

Environ Res 2021 Sep 14:112065. Epub 2021 Sep 14.

Department of Clinical Epidemiology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, Liaoning, 110004, China. Electronic address:

Background And Aims: The coronavirus disease 2019 (COVID-19) pandemic is severely threatening and challenging public health worldwide. Epidemiological studies focused on the influence of outdoor air pollution (AP) on COVID-19 risk have produced inconsistent conclusions. We aimed to quantitatively explore this association using a meta-analysis. Read More

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September 2021

Size-segregated physicochemical properties of inhalable particulate matter in a tunnel-ventilated layer house in China.

Environ Res 2021 Sep 14:112064. Epub 2021 Sep 14.

College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China. Electronic address:

This study investigated the physicochemical properties of the particles in a typical commercial laying hen barn in Southeast China. Mass concentrations and size distributions of the particulate matter (PM) and the key components (incl. organic carbon (OC), element carbon (EC), and the water-soluble inorganic ions (WSIIs)) were analyzed. Read More

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September 2021

Histological Findings After Aortic Cross-Clamping in Preclinical Animal Models.

J Neuropathol Exp Neurol 2021 Sep 17. Epub 2021 Sep 17.

Department of Anesthesiology,Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.

Spinal cord ischemic injury and paralysis are devastating complications after open surgical repair of thoracoabdominal aortic aneurysms. Preclinical models have been developed to simulate the clinical paradigm to better understand the neuropathophysiology and develop therapeutic treatment. Neuropathological findings in the preclinical models have not been comprehensively examined before. Read More

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September 2021

Adipose tissue and adipose secretome in systemic sclerosis.

Curr Opin Rheumatol 2021 Sep 15. Epub 2021 Sep 15.

Department of Rheumatology, University Medical Centre Ljubljana Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia Center for Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland FAMNIT, University of Primorska, Koper, Slovenia.

Purpose Of Review: Adipose tissue is closely associated with systemic sclerosis (SSc)-pathology, both anatomicaly and functionaly matter. This review focuses on local effects of adipocytes in the context of adipose to mesenchymal transdifferentiation (AMT), effects of the adipose stromal vascular fraction on SSc pathogenesis and systemic effects of adipose tissue secretome.

Recent Findings: Novel populations of fibroblasts evolving from adipose tissue were identified- for example COL11+ cancer-associated fibroblasts differentiated from adipose-derived stromal cells. Read More

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September 2021

Chemical speciation and risk assessment of heavy metals in biochars derived from sewage sludge and anaerobically digested sludge.

Water Sci Technol 2021 Sep;84(5):1079-1089

School of Environmental and Municipal Engineering, Tianjin Chengjian University, Tianjin 300384, China E-mail: Tianjin Key Laboratory of Aqueous Science and Technology, Tianjin 300384, China.

Dewatered sewage sludge (DSS) and anaerobically digested sludge (ADS) were pyrolyzed at 550 °C to investigate the characteristics of derived biochar and evaluate the risk of heavy metals (Cr, Ni, Cu, As, Cd, and Pb). The results showed that the pH value of the biochar derived from DSS (DSS-C) was slightly lower than that of the biochar derived from ADS (ADS-C), while DSS-C presented relatively higher specific surface area and total pore volume. DSS-C also showed higher H/C and lower O/C ratios than ADS-C, indicating a higher aromatic condensation and a lower polarity. Read More

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September 2021

Quality, health, and spending in Medicare Advantage and traditional Medicare.

Am J Manag Care 2021 Sep;27(9):395-400

Berkeley Research Group, 1800 M St NW, Second Fl, Washington, DC 20036. Email:

Objectives: To compare Medicare Advantage (MA) and traditional Medicare (TM) performance on quality, health, and cost outcomes in peer-reviewed literature published since 2010.

Study Design: Systematic review of peer-reviewed papers published between January 1, 2010, and May 1, 2020.

Methods: To identify relevant research papers, we searched MEDLINE, EBSCO, and ProQuest. Read More

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September 2021

Highly Selective Tandem Electroreduction of CO2 to Ethylene over Atomically Isolated Nickel-Nitrogen Site/Copper Nanoparticle Catalysts.

Angew Chem Int Ed Engl 2021 Sep 17. Epub 2021 Sep 17.

Chinese Academy of Sciences Fujian Institute of Research on the Structure of Matter, state key laboratory of structural chemistry, CHINA.

Highly selective CO 2 electroreduction reaction (CO 2 RR) into desired value-added multicarbon products such as C 2 H 4 is of great importance but largely limited by the multi-electron transfer process and sluggish C-C coupling step at one single active site. Herein, an effective tandem catalysis strategy is developed to improve the selectivity of the CO 2 RR towards C 2 H 4 by multiple distinct catalytic sites in local vicinity. An earth-abundant elements-based tandem electrocatalyst PTF(Ni)/Cu is constructed by uniformly dispersing Cu nanoparticles (NPs) on the porphyrinic triazine framework anchored with atomically isolated nickel-nitrogen sites (PTF(Ni)) for the enhanced CO 2 RR to produce C 2 H 4 . Read More

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September 2021

Redefining varicose projection astrocytes in primates.

Glia 2021 Sep 17. Epub 2021 Sep 17.

Department of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, California, USA.

Varicose projection astrocytes (VP-As) are found in the cerebral cortex and have been described to be specific to humans and chimpanzees. To further examine the phylogenetic distribution of this cell type, we analyzed cortical tissue from several primates ranging from primitive primates to primates evolutionary closer to human such as apes. We specifically analyzed tissue from four strepsirrhine species, one tarsier, six species of platyrrhine monkeys, ten species of cercopithecoid monkeys, two hylobatid ape species, four to six cases each of chimpanzee, bonobo, gorilla, and orangutan, and thirteen human. Read More

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September 2021

Muscle strength and its association with cardiometabolic variables in adolescents: does the expression of muscle strength values matter?

World J Pediatr 2021 Sep 17. Epub 2021 Sep 17.

Research Center in Kinanthropometry and Human Performance, Federal University of Santa Catarina, Trinity University Campus, Florianópolis, SC, CEP 88010-970, Brazil.

Background: We investigate the association between different muscle strength (MS) indices with cardiometabolic variables in adolescents.

Methods: Cross-sectional study comprising 351 adolescents (male 44.4%, age 16. Read More

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September 2021

Tau deposition and structural connectivity demonstrate differential association patterns with neurocognitive tests.

Brain Imaging Behav 2021 Sep 17. Epub 2021 Sep 17.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 355 West 16th Street, Suite 4100, Indianapolis, IN, 46202, USA.

Tau neurofibrillary tangles have a central role in the pathogenesis of Alzheimer's Disease (AD). Mounting evidence indicates that the propagation of tau is assisted by brain connectivity with weakened white-matter integrity along the propagation pathways. Recent advances in tau positron emission tomography tracers and diffusion magnetic resonance imaging allow the visualization of tau pathology and white-matter connectivity of the brain in vivo. Read More

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September 2021

GIS-based air quality modelling: spatial prediction of PM10 for Selangor State, Malaysia using machine learning algorithms.

Environ Sci Pollut Res Int 2021 Sep 17. Epub 2021 Sep 17.

Geospatial Analysis and Modelling (GAM) Research Laboratory, Department of Civil and Environmental Engineering, Universiti Teknologi PETRONAS (UTP), 32610, Seri Iskandar, Perak, Malaysia.

Rapid urbanization has caused severe deterioration of air quality globally, leading to increased hospitalization and premature deaths. Therefore, accurate prediction of air quality is crucial for mitigation planning to support urban sustainability and resilience. Although some studies have predicted air pollutants such as particulate matter (PM) using machine learning algorithms (MLAs), there is a paucity of studies on spatial hazard assessment with respect to the air quality index (AQI). Read More

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September 2021

Biological assessment of contaminated shooting range soil using earthworm biomarkers.

Ecotoxicology 2021 Sep 17. Epub 2021 Sep 17.

Department of Environmental Sciences, Vytautas Magnus University, University 10, Academy, Kaunas, Lithuania.

Environmental contamination at shooting ranges is a widely known ecological problem. The aim of the study was to evaluate the extent of contamination and the ecotoxicity of a shooting range soil assessing the physiological and biochemical effects on earthworm Eisenia fetida (Savigny). Adult E. Read More

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September 2021

Controlling the organization and stretchability of poly(3-butylthiophene) spherulites.

Soft Matter 2021 Sep 17. Epub 2021 Sep 17.

Beijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Xinjiekouwai Street No. 19, Beijing 100875, P. R. China.

In this work, we report a simple strategy to readily prepare poly(3-butylthiophene) (P3BT) films with patterned spherulites by brushing the P3BT film surface and annealing the film with carbon disulfide (CS) vapor. The spherulites nucleated preferentially at the mechanically scratched areas over the unscratched region of the film. The ridge (formed at the side of the scratch) hinders the diffusion of the P3BT molecules, promoting the aggregation and nucleation of P3BT along the ridge to form spherulites upon the CS vapor-annealing. Read More

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September 2021