13,879 results match your criteria maternal obesity

Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning.

PLoS Negl Trop Dis 2021 Jul 28;15(7):e0008824. Epub 2021 Jul 28.

Department of Health Policy Planning and Management, University of Health and Allied Sciences, Ho, Ghana.

Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. Read More

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Low fetal fraction in obese women at first trimester cell-free DNA based prenatal screening is not accompanied by differences in total cell-free DNA.

Prenat Diagn 2021 Jul 23. Epub 2021 Jul 23.

Department of Obstetrics & Gynecology, Division of Maternal Fetal Medicine, University of Washington, Seattle, WA.

Objective: Reasons for first trimester non-invasive prenatal screening (NIPS) test failure in obese women remain elusive. As dilution from maternal sources may be explanatory, we determined the relationship between obesity, fetal fraction (FF), and total cfDNA using our NIPS platform.

Methods: We assessed differences in first trimester (≤14 weeks) FF, indeterminate rate, and total cfDNA between obese (n=518) and normal weight women (n=237) after exclusion of confounders (anticoagulation, autoimmunity, aneuploidy) and controlling for covariates. Read More

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Parenting style as a predictor of dietary score change in children from ages 4 to 14 years. Findings from the Longitudinal Study of Australian Children.

Public Health Nutr 2021 Jul 23:1-20. Epub 2021 Jul 23.

Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences Deakin University, Geelong, Australia.

Objective: To examine associations between parenting style and changes in dietary quality score across childhood.

Design: This longitudinal analysis included the child's frequency of consumption for twelve food and drink items reported by mothers (at child ages 4-8 years) and children (at ages 10-14 years) during face-to-face interviews biennially. These items were combined into dietary scores based on the Australian Dietary Guidelines. Read More

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Risk factors for surgical site infection following cesarean delivery: a hospital-based case-control study.

Acta Obstet Gynecol Scand 2021 Jul 26. Epub 2021 Jul 26.

Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.

Introduction: Cesarean section is the single most important risk factor for postpartum infection. Where the rest of the world shows increasing trends, the cesarean section rates are low in Norway and risk factors for infection after cesarean section may differ in high and low cesarean section settings. The goal of this study was to examine independent risk factors for surgical site infection after cesarean delivery in a setting of low cesarean section rates. Read More

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Effect of overweight/obesity on caesarean section occurrence among reproductive-aged women in Ethiopia: a secondary data analysis.

BMJ Nutr Prev Health 2021 15;4(1):111-114. Epub 2021 Feb 15.

Department of Pharmacy, College of Medcine and Health Science, Wollo University, Dessie, Ethiopia.

Background: The burden of overweight/obesity increased worldwide and it has unpredictable effect on maternal morbidity and mortality. Different adverse perinatal outcomes observed in overweight/obese women, of those caesarean section occurred frequently. In Ethiopia, the national caesarean section and overweight/obesity rate among reproductive-aged women increased tremendously. Read More

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February 2021

Maternal High-Fat Diet Exposure During Gestation and Lactation Affects Intestinal Development in Suckling Rats.

Front Physiol 2021 8;12:693150. Epub 2021 Jul 8.

Department of Animal Physiology, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jabłonna, Poland.

Maternal health and diet influence metabolic status and play a crucial role in the development of metabolic function in offspring and their susceptibility to metabolic diseases in adulthood. The pathogenesis of various metabolic disorders is often associated with impairment in intestinal structure and function. Thus, the aim of the current study was to determine the effects of maternal exposure to a high fat diet (HFD), during gestation and lactation, on small intestinal growth and maturation in rat pups at 21 days old. Read More

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Maternal Childhood Adversity as a Risk for Perinatal Complications and NICU Hospitalization.

J Pediatr Psychol 2021 Jul 20. Epub 2021 Jul 20.

Center for Integrative Research on Childhood Adversity, Oklahoma State University-Center for Health Sciences.

Objective: To examine maternal childhood adversity in relation to increased risk for maternal and infant perinatal complications and newborn Neonatal Intensive Care Unit (NICU) admittance.

Methods: A sample of 164 women recruited at their first prenatal appointment participated in a longitudinal study through 6 weeks postdelivery. Participants self-reported on their adverse childhood experiences (ACEs), negative health risks (overweight/obesity, smoking, and alcohol use), adverse infant outcomes, NICU admittance, and maternal perinatal complications across three pregnancy assessments and one post-birth assessment. Read More

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Associations of influenza, chronic comorbid conditions, and severe maternal morbidity among U.S. pregnant women with influenza at delivery hospitalization, 2000-2015.

Am J Obstet Gynecol MFM 2021 Jul 22:100445. Epub 2021 Jul 22.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Ohio State University. Electronic address:

Background: Chronic comorbid conditions increase the risk of influenza-related morbidity. Whether this holds for pregnant women who are at high risk of complications from influenza remains to be determined.

Objectives: To determine whether chronic comorbid conditions are associated with an increased risk of severe maternal morbidity (SMM) among pregnant women with an influenza diagnosis at delivery hospitalization. Read More

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Physical activity behaviours in adolescence: current evidence and opportunities for intervention.

Lancet 2021 Jul 21. Epub 2021 Jul 21.

Population and Public Health Sciences, Pennington Biomedical Research Center, Baton Rouge, LA, USA.

Young people aged 10-24 years constitute 24% of the world's population; investing in their health could yield a triple benefit-eg, today, into adulthood, and for the next generation. However, in physical activity research, this life stage is poorly understood, with the evidence dominated by research in younger adolescents (aged 10-14 years), school settings, and high-income countries. Globally, 80% of adolescents are insufficiently active, and many adolescents engage in 2 h or more daily recreational screen time. Read More

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Maternal body mass index in pregnancy and mental disorders in adult offspring: a record linkage study in Aberdeen, Scotland.

Sci Rep 2021 Jul 23;11(1):15132. Epub 2021 Jul 23.

Centre for Cardiovascular Science and Tommy's Centre for Fetal and Maternal Health, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

Maternal obesity in pregnancy predicts offspring psychopathology risk in childhood but it remains unclear whether maternal obesity or underweight associate with adult offspring mental disorders. We examined longitudinally whether maternal body mass index (BMI) in pregnancy predicted mental disorders in her offspring and whether the associations differed by offspring birth year among 68,571 mother-child dyads of Aberdeen Maternity and Neonatal Databank, Scotland. The offspring were born 1950-1999. Read More

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Observed magnitude and trends in socioeconomic and geographic area inequalities in obesity prevalence among non-pregnant women in Chad: evidence from three waves of Chad demographic and health surveys.

Arch Public Health 2021 Jul 23;79(1):133. Epub 2021 Jul 23.

Department of Medicine, College of Medicine and Health Science, Wolketie University, Wolkite, Ethiopia.

Background: While the prevalence of obesity is increasing worldwide, the growing rates of overweight and obesity in developing countries are disquieting. Obesity is widely recognized as a risk factor for non-communicable diseases (NCDs), including diabetes, cancer and cardiovascular diseases. Available evidence on whether obesity has been more prevalent among higher or lower socioeconomic groups, across regions and urban-rural women's are inconsistent. Read More

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Sleep disorders in a sample of Lebanese children: the role of parental mental health and child nutrition and activity.

BMC Pediatr 2021 Jul 23;21(1):324. Epub 2021 Jul 23.

Research Department, Psychiatric Hospital of the Cross, Jal Eddib, Lebanon.

Background: Sleep habits are an important component of a child's health and it is affected by parent-child relationship. Also, child's diet and nutrition appear to be an important factor affecting sleep health. Few studies have addressed the effect of parental emotional disturbance that can leave on children's sleep. Read More

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The Cumulative Risk of Prenatal Exposures to Chemical and Non-Chemical Stressors on Birth Outcomes in Suriname.

Int J Environ Res Public Health 2021 Jul 20;18(14). Epub 2021 Jul 20.

Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.

The cumulative exposure to chemical and non-chemical stressors may have an impact on birth outcomes. The aim of this study is to examine the cumulative exposure of a mixture of chemicals (mercury, lead, selenium and tin) and non-chemical stressors (social support, perceived stress, probable depression and BMI) on birth outcomes (birthweight, gestational age at birth, and Apgar score at 5 min). The study population is a subset ( = 384) of the Caribbean Consortium for Research in Environmental and Occupational Health-MeKiTamara prospective cohort study. Read More

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Lipid Metabolism Is Dysregulated before, during and after Pregnancy in a Mouse Model of Gestational Diabetes.

Int J Mol Sci 2021 Jul 12;22(14). Epub 2021 Jul 12.

University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Addenbrooke's Treatment Centre, Keith Day Road, Cambridge CB2 0QQ, UK.

The aim of the current study was to test the hypothesis that maternal lipid metabolism was modulated during normal pregnancy and that these modulations are altered in gestational diabetes mellitus (GDM). We tested this hypothesis using an established mouse model of diet-induced obesity with pregnancy-associated loss of glucose tolerance and a novel lipid analysis tool, Lipid Traffic Analysis, that uses the temporal distribution of lipids to identify differences in the control of lipid metabolism through a time course. Our results suggest that the start of pregnancy is associated with several changes in lipid metabolism, including fewer variables associated with de novo lipogenesis and fewer PUFA-containing lipids in the circulation. Read More

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Sex differences in the impact of parental obesity on offspring cardiac SIRT3 expression, mitochondrial efficiency and diastolic function early in life.

Am J Physiol Heart Circ Physiol 2021 07 23. Epub 2021 Jul 23.

Department of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiorenal and Metabolic Diseases Research Center, University of Mississippi Medical Center, Jackson, MS, United States.

Previous studies suggest that parental obesity may adversely impact long-term metabolic health of the offspring. We tested the hypothesis that parental (paternal + maternal) obesity impairs cardiac function in the offspring early in life. Within 1-3 days after weaning, offspring from obese rats fed a high fat diet (HFD-Offs) and age-matched offspring from lean rats (ND-Offs) were submitted to echocardiography and cardiac catheterization for assessment of pressure-volume relationships. Read More

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Association between the use of antibiotics during pregnancy and obesity in 5-year-old children.

Transl Pediatr 2021 Jun;10(6):1686-1691

Child Healthcare Department, Haikou Hospital of the Maternal and Child Health, Haikou, China.

Background: Obesity is an epidemic that must arouse our attention. The purpose of this research is to investigate the relationship between antibiotic use during pregnancy and childhood obesity in 5-year-old Chinese children.

Methods: A total of 132 5-year-old children born in our hospital from January 2014 to January 2016 were included. Read More

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Anthropometric measures and blood pressure of Greenlandic preschool children.

Int J Circumpolar Health 2021 Dec;80(1):1954382

Center for Arctic Health and Molecular Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark.

The study aims to describe anthropometric data of Greenlandic preschool children, blood pressure (BP) measures and effects of maternal smoking during pregnancy in a follow-up of the ACCEPT birth cohort. The study included 102 children (55 boys and 47 girls) aged 3.5-5. Read More

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December 2021

Periconceptional maternal body mass index and the impact on post-implantation (sex-specific) embryonic growth and morphological development.

Int J Obes (Lond) 2021 Jul 21. Epub 2021 Jul 21.

Departments of Obstetrics and Gynecology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Objective: Women with obesity have an increased risk of pregnancy complications. Although complications generally present in the second and third trimester of pregnancy, most of them develop in the periconception period. Moreover, fetal sex also impacts pregnancy course and outcome. Read More

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Maternal obesity increases the risk and severity of NAFLD in offspring.

J Hepatol 2021 Jul 10. Epub 2021 Jul 10.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Orebro University Hospital, Orebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, UK; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.

Background And Aims: Maternal obesity has been linked to the development of cardiovascular disease and diabetes in offspring, but its relationship to non-alcoholic fatty liver disease (NAFLD) is unclear.

Methods: Through the nationwide ESPRESSO cohort study we identified all individuals in Sweden with biopsy-verified NAFLD ≤25 years of age diagnosed between 1992 and 2016 (n=165). These were matched on age, sex, and calendar year with up to 5 controls (n=717). Read More

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Hepatic fat in early childhood is independently associated with estimated insulin resistance: The Healthy Start Study.

J Clin Endocrinol Metab 2021 Jul 21. Epub 2021 Jul 21.

Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.

Background: Fatty liver disease is a common metabolic abnormality in adolescents with obesity, but remains under-studied in early childhood.

Objectives: To describe hepatic fat deposition in prepubertal children and examine associations with metabolic markers and body composition.

Methods: Data were from 286 children ages 4-8 years old in the Healthy Start Study, a longitudinal pre-birth cohort in Colorado. Read More

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Cardiometabolic consequences of maternal hyperandrogenemia in male offspring.

Physiol Rep 2021 Jul;9(14):e14941

Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS, USA.

Polycystic ovary syndrome (PCOS) in women is characterized by hyperandrogenemia, obesity, and oligo- or anovulation. In addition, women with PCOS are often obese, with insulin resistance, hyperlipidemia, and elevated blood pressure. The cardiometabolic consequences for the male offspring of maternal hyperandrogenemia are unclear. Read More

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The WOMBS Framework: A review and new theoretical model for investigating pregnancy-related weight stigma and its intergenerational implications.

Obes Rev 2021 Jul 21. Epub 2021 Jul 21.

Department of Kinesiology, Faculty of Applied Health Sciences, Brock University, St. Catharines, Ontario, Canada.

As the growing weight stigma literature has developed, one critically relevant and vulnerable population has received little consideration-pregnant and postpartum women. Because weight fluctuations are inherent to this life phase, and rates of prepregnancy overweight and obesity are already high, this gap is problematic. More recently, however, there has been a rising interest in pregnancy-related weight stigma and its consequences. Read More

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Treadmill exercise alleviates short-term memory impairments of pups born to old and obese mother rats.

Young Jun Ko

J Exerc Rehabil 2021 Jun 30;17(3):153-157. Epub 2021 Jun 30.

Major in Sport Service Practice, College of Welfare Convergence, Kangnam University, Yongin, Korea.

Obesity causes atrophy of the brain, leading to deterioration in working memory, learning, and cognitive function. The status of short-term memory in rat pups born to older obese mother rats was verified, and the effect of treadmill exercise on short-term memory in rat pups was investigated. Step-down avoidance test for short-term memory, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) staining for apoptosis, and immunohistochemistry for Ki67 for new cell generation were done. Read More

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Ideal Cardiovascular Health and Vascular Phenotype Associations in Mothers with Obesity and Their Six-Year-Old Children.

Diabetes Metab Syndr Obes 2021 13;14:3187-3197. Epub 2021 Jul 13.

Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: Heredity and family-shared lifestyle contribute to cardiovascular risk, but the magnitude of their influence on arterial structure and function in early childhood is unknown. We aimed to assess associations between child and maternal ideal cardiovascular health, maternal subclinical atherosclerosis, and child arterial phenotype.

Methods: Cross-sectional analysis of 201 mother-child pairs originating from the Finnish Gestational Diabetes Prevention Study (RADIEL) longitudinal cohort was done at child age 6. Read More

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Sleep duration and eating behaviours are associated with body composition in 5-year-old children: Findings from the ROLO longitudinal birth cohort study.

Br J Nutr 2021 Jul 21:1-30. Epub 2021 Jul 21.

UCD Perinatal Research Centre, School of Medicine, University College Dublin, National Maternity Hospital, Dublin 2, Ireland.

Inadequate sleep and poor eating behaviours are associated with higher risk of childhood overweight and obesity. Less is known about the influence sleep has on eating behaviours and consequently body composition. Furthermore, whether associations differ in boys and girls has not been investigated extensively. Read More

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Electrocardiographic abnormalities, preclinical carotid atherosclerosis andcardiovascular risk, in an apparently healthy real-world population: data from the project "No Stroke, No Infarction" of the rotary international - District 2110 "Sicily & Malta".

Int Angiol 2021 Jul 20. Epub 2021 Jul 20.

G. D'Alessandro Department of Health Promotion and of Maternal and Child, Internal, and Specialist Medicine (PROMISE), University of Palermo, Palermo, Italy.

Background: Cardiovascular diseases (CVDs) represent important causes of morbidity and mortality. Our study aimed to evaluate cardiovascular risk using the EUROSCORE, ECG and carotid ultrasound for prevention purpose in a 50-70 years population and companions asymptomatic and without CVD.

Methods: History of CVD, risk factors (RFs), ECG and carotid ultrasound were evaluated. Read More

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Environmental and Genetic Risk Factors of Congenital Anomalies: an Umbrella Review of Systematic Reviews and Meta-Analyses.

J Korean Med Sci 2021 Jul 19;36(28):e183. Epub 2021 Jul 19.

Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.

Background: The prevalence of congenital anomalies in newborns in South Korea was 272.9 per 100,000 in 2005, and 314.7 per 100,000 in 2006. Read More

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The Association of Familial Hypertension and Risk of Gestational Hypertension and Preeclampsia.

Int J Environ Res Public Health 2021 Jul 1;18(13). Epub 2021 Jul 1.

Medical Faculty, Lazarski University, 02-662 Warsaw, Poland.

It has not been established how history of hypertension in the father or mother of pregnant women, combined with obesity or smoking, affects the risk of main forms of pregnancy-induced hypertension. A cohort of 912 pregnant women, recruited in the first trimester, was assessed; 113 (12.4%) women developed gestational hypertension (GH), 24 (2. Read More

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Association between Maternal Obesity Class, Adherence to Labor Guidelines, and Perinatal Outcomes.

AJP Rep 2021 Apr 15;11(2):e105-e112. Epub 2021 Jul 15.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.

 Data are limited concerning rates of perinatal complications in women with a body mass index (BMI) ≥40 kg/m2 compared to women with other BMI classes when guidelines for the safe prevention of the primary cesarean delivery are applied.  The aim of the study is to evaluate labor guideline adherence by BMI class and to compare perinatal outcomes across BMI classes with guideline adherent management.  This retrospective study included low-risk women admitted for delivery between April 2014 and April 2017 after the labor guidelines were implemented. Read More

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