39 results match your criteria massive fluid-filled


Challenging diagnostic work-up of a massive fluid-filled structure in the cranial abdomen of a cat.

Tierarztl Prax Ausg K Kleintiere Heimtiere 2021 Oct 12. Epub 2021 Oct 12.

Small Animal Clinic, University of Veterinary Medicine Hannover, Foundation.

A 9-year-old female, neutered European shorthair cat was presented with acute vomiting, obvious jaundice and painful enlargement of the abdomen. Icteric skin and mucous membranes in addition to severe bilirubinaemia (mainly direct bilirubin) and a large increase in liver enzyme activities were the main findings at the initial examination. Radio- and ultrasonographic evaluation revealed a massive fluid-filled structure caudal to the liver displacing abdominal organs, in particular the stomach. Read More

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October 2021

Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury.

Cell Mol Neurobiol 2020 Apr 14;40(3):369-380. Epub 2019 Sep 14.

Department of Pathology and Laboratory Medicine, University of Western Ontario, London, N6A 5C1, Canada.

Besides other causes, ischemia and Alzheimer's disease pathology is also linked to decreased cerebral blood flow (CBF). There is little or no consensus about the role of neuroglial cells in maintaining CBF in various neuropathologies. This consensus becomes scarcer when it comes to clinical and experimental cases of comorbid Abeta-amyloid (Aβ) toxicity and ischemia. Read More

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Clinical problems in hemodialysis patients with autosomal dominant polycystic kidney disease.

Semin Dial 2018 05 17;31(3):268-277. Epub 2018 Apr 17.

Department of Nephrology, Sutcu Imam University Medical Faculty, Kahramanmaras, Turkey.

Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by massive enlargement of fluid-filled cysts in the kidney. Due to its genetic pattern, the disease differs from other CKD. ADPKD is a multi-system, progressive disorder which is frequently complicated with hypertension, cardiovascular events and cerebrovascular disease. Read More

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Giant Tumefactive Perivascular Spaces: A Case Report and Literature Review.

World Neurosurg 2018 Apr 31;112:201-204. Epub 2018 Jan 31.

Division of Neurosurgery, King Saud University, Riyadh, Saudi Arabia.

Background: Perivascular spaces (PVS), also known as Virchow-Robin spaces, are pial-lined, interstitial fluid-filled structures in the brain that accompany cerebral vessels as they penetrate the cerebral substance. In healthy individuals, a PVS diameter of <2 mm is considered normal and can typically be seen within the white matter on magnetic resonance imaging (MRI). When PVS dilate, they are considered benign lesions and are associated with aging and other risk factors. Read More

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Iron diapirs entrain silicates to the core and initiate thermochemical plumes.

Nat Commun 2018 01 4;9(1):71. Epub 2018 Jan 4.

Department of Earth and Planetary Sciences, University of New Mexico, Albuquerque, NM, 87131, USA.

Segregation of the iron core from rocky silicates is a massive evolutionary event in planetary accretion, yet the process of metal segregation remains obscure, due to obstacles in simulating the extreme physical properties of liquid iron and silicates at finite length scales. We present new experimental results studying gravitational instability of an emulsified liquid gallium layer, initially at rest at the interface between two glucose solutions. Metal settling coats liquid metal drops with a film of low density material. Read More

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January 2018

Quercetin inhibits renal cyst growth in vitro and via parenteral injection in a polycystic kidney disease mouse model.

Food Funct 2018 Jan;9(1):389-396

Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu, China.

Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by massive enlargement of fluid-filled cysts in the kidney. There is an urgent need to develop effective ADPKD therapies. We used an in vitro Madin-Darby canine kidney (MDCK) cyst model and a murine embryonic kidney cyst model to evaluate whether quercetin inhibits cyst development. Read More

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January 2018

Bi-directional hepatic hydrothorax.

World J Hepatol 2017 May;9(13):642-644

Madhan Nellaiyappan, Anastasios Kapetanos, Department of Medicine, Allegheny Health Network, Pittsburgh, PA 15212, United States.

A 59-year-old male with alcoholic cirrhosis presented to our hospital with an acutely painful umbilical hernia, and 4 mo of exertional dyspnea. He was noted to be tachypneic and hypoxic. He had a massive right sided pleural effusion with leftward mediastinal shift and gross ascites, with a tense, fluid-filled, umbilical hernia. Read More

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Massive hemoperitoneum following spontaneous rupture of an arterial aneurysm overlying a uterine myoma.

Int J Clin Exp Med 2015 15;8(2):3002-5. Epub 2015 Feb 15.

Department of Pathology, Shizuoka Saiseikai General Hospital Shizuoka, Japan.

Intraperitoneal hemorrhage caused by a uterine myoma is rare. A 54-year-old woman was admitted to the emergency room; on admission, she was in cardiopulmonary arrest with pulseless electrical activity. Transabdominal ultrasonography revealed hyperechoic fluid filled almost the entire abdominal cavity. Read More

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Suppurative meckel diiverticulum in a 3-year-old girl presenting with periumbilical cellulitis.

Pediatr Gastroenterol Hepatol Nutr 2015 Mar 30;18(1):66-70. Epub 2015 Mar 30.

Department of Pediatrics, Institute of Health Science, Gyeongsang National University Hospital, Jinju, Korea.

Meckel diverticulum (MD) is one of the most common congenital gastrointestinal anomalies and occurs in 1.2-2% of the general population. MD usually presents with massive painless rectal bleeding, intestinal obstruction or inflammation in children and adults. Read More

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Postmortem magnetic resonance appearances of congenital high airway obstruction syndrome.

Pediatr Radiol 2015 Apr 5;45(4):556-61. Epub 2014 Sep 5.

Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK,

Background: Congenital high airway obstruction syndrome (CHAOS) is a rare life-threatening condition characterised by complete or near-complete developmental obstruction of the foetal airway. Although antenatal imaging findings have been described, the postmortem MRI findings have not been reported.

Objective: To present postmortem MRI features of CHAOS. Read More

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Perioperative management of hysterectomy in a patient with polycystic kidney disease.

J Clin Diagn Res 2014 Jul 20;8(7):GD03-4. Epub 2014 Jul 20.

Post Graduate Student, Department of Anaesthesia, Karnataka Institute of Medical Sciences , Hubli, Karnataka, India .

Polycystic disease of the kidney, inherited as an autosomal dominant trait is characterised by progressive expansion of numerous fluid-filled cysts resulting in massive enlargement of the kidneys ultimately resulting in kidney failure. An understanding of alterations in the renal physiology due to hemodynamic changes is important for successful perioperative management. We report a successful perioperative management of a vaginal hysterectomy in a female patient with adult polycystic kidney disease. Read More

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Abdominal chronic expanding hematoma causing iron-deficiency anemia in a dog.

J Am Anim Hosp Assoc 2014 Sep-Oct;50(5):350-5

Veterinary Health Center (L.S., K.H., A.H., T.L.) and Veterinary Diagnostic Laboratory (S.G.), Kansas State University, Manhattan, KS.

A 2 yr old spayed female mixed-breed Irish wolfhound was referred for assessment of anemia and slowly progressing abdominal distention. At the time of admission, the dog had marked anemia and thrombocytosis, a decreased serum iron concentration, and a normal coagulation profile. An ultrasound examination showed a massive fluid-filled cavitated structure in the abdominal cavity. Read More

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Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosus.

Infect Immun 2014 Aug 19;82(8):3164-76. Epub 2014 May 19.

Cátedra de Inmunología, Departamento de Biociencias (Facultad de Química) e Instituto de Química Biológica (Facultad de Ciencias), Universidad de la República, Montevideo, Uruguay

The larval stage of the cestode parasite Echinococcus granulosus causes hydatid disease in humans and livestock. This infection is characterized by the growth in internal organ parenchymae of fluid-filled structures (hydatids) that elicit surprisingly little inflammation in spite of their massive size and persistence. Hydatids are protected by a millimeter-thick layer of mucin-based extracellular matrix, termed the laminated layer (LL), which is thought to be a major factor determining the host response to the infection. Read More

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Percutaneous sclerotherapy for treatment of tumoral calcinosis.

J Vasc Interv Radiol 2014 May;25(5):735-8

Department of Radiology, University of Washington, Box 357115, 1959 NE Pacific Street, Seattle, WA 98195. Electronic address:

Massive tumoral calcinosis developed in a 29-year-old woman with type 1 diabetes and failed pancreas and kidney transplant on peritoneal dialysis. The patient had a symptomatic calcified, fluid-filled posterior thigh mass. After percutaneous drainage of 260 mL of milky fluid, she had rapid recurrence of the collection. Read More

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Differential Expression of PKD2-Associated Genes in Autosomal Dominant Polycystic Kidney Disease.

Genomics Inform 2012 Mar 31;10(1):16-22. Epub 2012 Mar 31.

Department of Biological Science, Sookmyung Women's University, Seoul 140-742, Korea.

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by formation of multiple fluid-filled cysts that expand over time and destroy renal architecture. The proteins encoded by the PKD1 and PKD2 genes, mutations in which account for nearly all cases of ADPKD, may help guard against cystogenesis. Previously developed mouse models of PKD1 and PKD2 demonstrated an embryonic lethal phenotype and massive cyst formation in the kidney, indicating that PKD1 and PKD2 probably play important roles during normal renal tubular development. Read More

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Prenatal sonography in hydranencephaly: findings during the early stages of disease.

J Ultrasound Med 2012 May;31(5):799-804

Fetal Medicine Center, Santiago, Chile.

The purpose of this report is to describe the prenatal sonographic findings in fetuses with hydranencephaly diagnosed during the early stages of disease. Four cases with characteristics of hydranencephaly were retrospectively identified from 2 Latin American fetal medicine referral centers. Information on maternal demographics, sonographic findings, antenatal courses, and pregnancy outcomes was retrieved from the ultrasound reports and medical records. Read More

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Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models.

Am J Physiol Renal Physiol 2012 May 15;302(10):F1234-42. Epub 2012 Feb 15.

Dept. of Pharmacology. School of Basic Medical Sciences, Peking Univ., 38 Xueyuan Lu, Haidian District, Beijing 100191, China.

Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disease characterized by massive enlargement of fluid-filled cysts in the kidney. However, there is no effective therapy yet for this disease. To examine whether ginkgolide B, a natural compound, inhibits cyst development, a Madin-Darby canine kidney (MDCK) cyst model, an embryonic kidney cyst model, and a PKD mouse model were used. Read More

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Full-term extrauterine abdominal pregnancy: a case report.

J Med Case Rep 2011 Oct 31;5:531. Epub 2011 Oct 31.

Department of Anesthesia, Maternity and Children Hospital, Jeddah, Saudi Arabia.

Introduction: Extrauterine abdominal pregnancy is extremely rare and is frequently missed during antenatal care. This is a report of a full-term extrauterine abdominal pregnancy in a primigravida who likely had a ruptured ectopic pregnancy with secondary implantation and subsequently delivered a healthy baby.

Case Presentation: A 23-year-old, Middle Eastern, primigravida presented at 14 weeks gestation with intermittent suprapubic pain and dysuria. Read More

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October 2011

Curcumin inhibits renal cyst formation and enlargement in vitro by regulating intracellular signaling pathways.

Eur J Pharmacol 2011 Mar 24;654(1):92-9. Epub 2010 Dec 24.

Department of Pharmacology, School of Basic Medical Sciences, Peking University, 38 Xueyuan Lu, Haidian, Beijing, China.

Autosomal dominant polycystic kidney disease, a common inherited disease affecting about 1/1000 and 1/400 live births, is characterized by massive enlargement of fluid-filled cysts and eventually causes renal failure. The purpose of this study is to identify the inhibitory effect of curcumin on renal cyst development and to investigate the inhibitory mechanism. Madin-Darby canine kidney (MDCK) cyst model and murine embryonic kidney cyst model were used to evaluate inhibitory activity. Read More

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PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease.

Am J Physiol Renal Physiol 2011 Feb 8;300(2):F465-74. Epub 2010 Dec 8.

Education and Research Center of Animal Models for Human Diseases, Fujita Health University, Toyoake, Aichi, Japan.

In autosomal recessive polycystic kidney disease (ARPKD), progressive enlargement of fluid-filled cysts is due to aberrant proliferation of tubule epithelial cells and transepithelial fluid secretion leading to extensive nephron loss and interstitial fibrosis. Congenital hepatic fibrosis associated with biliary cysts/dilatations is the most common extrarenal manifestation in ARPKD and can lead to massive liver enlargement. Peroxisome proliferator-activated receptor γ (PPAR-γ), a member of the ligand-dependent nuclear receptor superfamily, is expressed in a variety of tissues, including the kidneys and liver, and plays important roles in cell proliferation, fibrosis, and inflammation. Read More

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February 2011

Diagnosis and management of fetal intrapericardial Morgagni diaphragmatic hernia with massive pericardial effussion.

J Pediatr Surg 2010 Feb;45(2):424-6

Unidad De Gestión Clinica De Genética, Reproducción Y Medicina Fetal, Hospitales Universitarios Virgen Del Rocío, 41013 Sevilla, Spain.

Herniation of the liver into the fluid-filled pericardial sac resulting in a thoracic mass is a particularly rare form of Morgagni hernia (congenital diaphragmatic hernia of Morgagni). We report an early antenatal diagnosis of congenital diaphragmatic hernia of Morgagni with pericardium effussion at 21 weeks' gestation. Two pericardiocentesis were performed at 21 and 22 4/7 weeks' gestation because of recurrence of pericardial effussion. Read More

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February 2010

Epizootic congenital hydranencephaly and abortion in cattle due to bluetongue virus serotype 8 in the Netherlands.

Tijdschr Diergeneeskd 2009 May;134(10):422-7

Animal Health Service, P.O. Box 9, 7400 AA Deventer, the Netherlands.

An outbreak of hydranencephaly in aborted foetuses and newborn calves occurred following the 2007 epidemic of bluetongue serotype 8 (BTV8\net2006) in the Netherlands. In total 35 aborted foetuses and 20 live-born calves, submitted from September 2007 to May 2008, were examined pathologically. Foetuses with gestational ages between 4 and 9 months (mean 6. Read More

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Pkd1 inactivation induced in adulthood produces focal cystic disease.

J Am Soc Nephrol 2008 Dec 5;19(12):2351-63. Epub 2008 Sep 5.

Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

Autosomal dominant polycystic kidney disease, the most common monogenetic disorder, is characterized by gradual replacement of normal renal parenchyma by fluid-filled cysts. Mutations in either PKD1 or PKD2 cause autosomal dominant polycystic kidney disease. Pkd1(-/-) or Pkd2(-/-) mice develop rapid renal cystic disease and exhibit embryonic lethality; this supports the "two-hit" hypothesis, which proposes that a germline mutation in PKD1 (or PKD2) followed by a second somatic mutation later in life is responsible for the phenotype. Read More

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December 2008

Fish mesonephric model of polycystic kidney disease in medaka (Oryzias latipes) pc mutant.

Kidney Int 2005 Jul;68(1):23-34

Laboratory of Freshwater Fish Stocks, Bioscience and Biotechnology Center, Nagoya University, Nagoya, Japan.

Background: Polycystic kidney disease (PKD) is a common hereditary disease. A number of murine and zebrafish mutants have been generated and used for the study of PKD as metanephric and pronephric models, respectively. Here, we report a medaka (Oryzias latipes) mutant that develops numerous cysts in the kidney in adulthood fish in an autosomal-recessive manner as a mesonephric model of PKD. Read More

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Seminoma in hybrid catfish [Clarias batrachus (Linnaeus) female x Clarias gariepinus (Burchell) male].

Indian J Exp Biol 2004 Jun;42(6):626-7

Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar 751 002, India.

Spontaneous testicular tumors, seminoma, were noticed in four male hybrid catfish (C. batrachus female x C. gariepinus male) after the age of two years. Read More

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Amassin, an olfactomedin protein, mediates the massive intercellular adhesion of sea urchin coelomocytes.

J Cell Biol 2003 Feb;160(4):597-604

Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA.

Sea urchins have a fluid-filled body cavity, the coelom, containing four types of immunocytes called coelomocytes. Within minutes after coelomic fluid is removed from the body cavity, a massive cell-cell adhesion of coelomocytes occurs. This event is referred to as clotting. Read More

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February 2003

Total and prolonged filling of the lungs with Ringer's solution under extracorporeal lung assist (ECLA) in dogs.

Acta Anaesthesiol Scand 2000 Sep;44(8):994-1001

Department of Anesthesiology, Kumamoto University School of Medicine, Japan.

Background: Massive alveolar lavage has been used clinically to remove materials accumulated in the alveoli. Recently, filling the lungs with oxygenated perfluorochemical (total liquid ventilation) has been investigated. However, effects of complete and prolonged filling of bilateral lungs with aqueous fluid, such as saline or Ringer's solution, has not been evaluated, although it is possible to sustain gas exchange without the natural lung by using extracorporeal circulation and an artificial lung (extracorporeal lung assist: ECLA). Read More

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September 2000

Imaging features of Mycobacterium avium-intracellulare complex (MAC) in children with AIDS.

Pediatr Radiol 2000 Jun;30(6):426-9

State University of New York, Health Science Center at Brooklyn, USA.

Purpose: The purpose of this paper was to review the imaging features of Mycobacterium avium-intracellulare complex (MAC) in 16 pediatric patients with human immunodeficiency virus (HIV).

Materials And Methods: We reviewed the pertinent clinical records of 16 children diagnosed with MAC between January 1990 and June 1998. These 16 cases were blood- or biopsy-proven to have MAC infection. Read More

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Fetus-in-fetu presenting as cystic meconium peritonitis: diagnosis, pathology, and surgical management.

J Pediatr Surg 2000 May;35(5):721-3

Department of Laboratory Medicine and Pathology, Stollery Children's Health Centre, University of Alberta, Edmonton, Canada.

Fetus-in-fetu (FIF), a rare congenital anomaly, is a fetus incorporating the well-differentiated tissue of its twin. The authors describe a newborn who presented with massive abdominal distension and severe respiratory distress. Abdominal x-rays showed multiple calcifications. Read More

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CT diagnosis of delayed presentation of congenital diaphragmatic hernia simulating massive pleuropneumonia.

Eur Radiol 1999 ;9(8):1672-4

Department of Diagnostic Imaging, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, IL-52621 Tel Hashomer, Israel.

A case of an 11-month-old infant with a delayed presentation of congenital diaphragmatic hernia is reported. Incarceration of the herniated colon caused a misleading appearance on the chest X-ray which was interpreted as massive pleuropneumonia. Computed tomography, performed because of continuing deterioration in the clinical condition, showed fluid-filled bowel loops in the chest and dilated bowel loops with air-fluid levels in the abdomen, suggesting the correct diagnosis. Read More

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November 1999