29,465 results match your criteria march 2020


Impact of Confinement in Patients under Long-Term Noninvasive Ventilation during the First Wave of the SARS-CoV-2 Pandemic: A Remarkable Resilience.

Respiration 2021 Jun 15:1-9. Epub 2021 Jun 15.

Division of Pulmonary Diseases, Geneva University Hospitals, Geneva, Switzerland.

Background: During the first wave of the SARS-CoV-2 pandemic in Switzerland, confinement was imposed to limit transmission and protect vulnerable persons. These measures may have had a negative impact on perceived quality of care and symptoms in patients with chronic disorders.

Objectives: To determine whether patients under long-term home noninvasive ventilation (LTHNIV) for chronic respiratory failure (CRF) were negatively affected by the 56-day confinement (March-April 2020). Read More

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Analysis of neurosurgical cases before and during the COVID-19 pandemic from a tertiary care centre in India.

World Neurosurg 2021 Jun 12. Epub 2021 Jun 12.

Professor, Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi India.

Objective: We present the unique administrative issues as well as specific patient and surgeon related challenges and solutions implemented while treating neurosurgical cases during the COVID pandemic vis-à-vis the pre COVID times at our tertiary care center.

Methods: This is a retrospective study comparing the outcome of the neurosurgical patients treated from the beginning of lockdown in India on 25 March 2020 to 30 November 2020 with that of same period in the previous year, 2019.

Results: We had a total of 687 admissions under neurosurgery this year during the study period as compared to 2550 admissions in 2019. Read More

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Telehealth Sustainability in a Neurosurgery Department During the COVID-19 Pandemic.

World Neurosurg 2021 Jun 12. Epub 2021 Jun 12.

Neurosurgery, University of Kentucky, 800 Rose St., Lexington, KY, 40508 USA; Brain Restoration Center, University of Kentucky, 800 Rose St., Lexington, KY, 40508 USA; Neuroscience, University of Kentucky, 800 Rose St., Lexington, KY, 40508 USA. Electronic address:

Background: The pandemic shifted the dynamics of healthcare and neurosurgical practice. Elective surgeries were suspended for 8 weeks in Kentucky. Our objective was to determine if telehealth (TH) visits could be sustained as an alternative to in-person visits. Read More

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Coronavirus Disease-2019 (COVID-19) and Pituitary Apoplexy: A Single-Center Case Series and Review of the Literature.

World Neurosurg 2021 Jun 12. Epub 2021 Jun 12.

Departments of Neurosurgery(,) University of Mississippi Medical Center, Jackson, MS, United States.

Background: Pituitary apoplexy (PA) is a rare but life-threatening condition characterized by pituitary infarction and hemorrhage, most often in the setting of a preexisting adenoma. The risk factors and mechanisms associated with PA are poorly understood. Although neurovascular manifestations of coronavirus disease-19 (COVID-19) infection have been documented, its association with PA is to be determined. Read More

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The partial femoral condyle focal resurfacing (HemiCAP-UniCAP) for treatment of full-thickness cartilage defects, systematic review and meta-analysis.

Acta Orthop Belg 2021 Mar;87(1):93-102

Knee osteochondral defects are a common problem among people, especially young and active patients. So effective joint preserving surgeries is essential to prevent or even delay the onset of osteoarthritis for these group of patients. This study aims to critically appraise and evaluate the evidence for the results and effectiveness of femoral condyle resurfacing (HemiCAP/ UniCAP) in treatment of patients with focal femoral condyle cartilage defect. Read More

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Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus-2.

Acta Paediatr 2021 Jun 15. Epub 2021 Jun 15.

Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

Multisystem inflammatory syndrome in children (MIS-C) is a novel disease that is associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) . Until now, only one study has attempted to estimate the incidence of MIS-C among SARS-CoV-2 infected children and adolescents . This study from the New York State has reported an incidence of MIS-C of 2 per 100,000 persons younger than 21 years of age between 1 March 1 and 10 May 2020. Read More

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Interventions to prevent preterm delivery in twin-twin transfusion with short cervix.

Ultrasound Obstet Gynecol 2021 Jun 15. Epub 2021 Jun 15.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology and Reproductive Sciences, UTHealth The University of Texas McGovern Medical School and the Fetal Center at Children's Memorial Hermann Hospital, Houston, TX.

Objective: Pre-operative short cervical length (CL) remains a major risk factor for preterm birth after laser surgery for twin-twin transfusion syndrome (TTTS). Interventions to prolong pregnancy remain elusive. The objective of this study is to compare secondary preventive methods used in the setting of short CL at the time of laser surgery by five North American Fetal Treatment Network (NAFTNet) centers. Read More

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Mathematical modeling of the transmission of SARS-CoV-2-Evaluating the impact of isolation in São Paulo State (Brazil) and lockdown in Spain associated with protective measures on the epidemic of CoViD-19.

PLoS One 2021 15;16(6):e0252271. Epub 2021 Jun 15.

Division of Allergy and Immunology, General Hospital of the Medicine School of University of São Paulo, São Paulo, São Paulo, Brazil.

Coronavirus disease 2019 (CoViD-19), with the fatality rate in elder (60 years old or more) being much higher than young (60 years old or less) patients, was declared a pandemic by the World Health Organization on March 11, 2020. A mathematical model considering young and elder subpopulations under different fatality rates was formulated based on the natural history of CoViD-19 to study the transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The model considered susceptible, exposed, asymptomatic, pre-symptomatic, mild CoViD-19, severe CoViD-19, and recovered compartments, besides compartments of isolated individuals and those who were caught by test. Read More

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Initial transperineal prostate biopsy experience at a high-volume center.

Can J Urol 2021 Jun;28(3):10692-10698

Department of Urology, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA.

Introduction: Transperineal prostate biopsy (TPBx) allows for prostate cancer detection with fewer infectious complications when compared to transrectal prostate biopsy (TRUSBx). We evaluated the initial experience of a single physician with no prior TPBx exposure, compared to TRUSBx and MRI/US fusion biopsy (MRIBx) performed by experienced physicians.

Materials And Methods: All consecutive patients undergoing prostate biopsy (June 2019-March 2020) were included. Read More

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Factors Driving Rapid Adoption of Telemedicine in an Academic Orthopedic Surgery Department.

Telemed J E Health 2021 Jun 15. Epub 2021 Jun 15.

Department of Orthopedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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Obesogenic Behaviors of Rural Children on School and Nonschool Days.

Child Obes 2021 Jun 15. Epub 2021 Jun 15.

School of Social Work, College of Health Professions and Sciences, University of Central Florida, Orlando, FL, USA.

Children living in rural areas are at increased risk of overweight and obesity compared with their urban-dwelling counterparts. The purpose of this study was to provide preliminary evidence of rural children's obesogenic behaviors ( activity, sedentary behaviors, sleep, and diet) during school days, nonschool weekdays, and weekend days. A repeated measures 14-day observational study was conducted early March 2020. Read More

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Assessment of the Prognostic Effect of Blood Urea Nitrogen to Serum Albumin Ratio in Patients with Fournier's Gangrene in a Referral Center.

Urol J 2021 Jun 15. Epub 2021 Jun 15.

Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To assess the prognostic effect of blood urea nitrogen to serum albumin ratio in patients with Fournier's gangrene (FG) in a referral center in order to reduce the mortality of FG patients.

Materials And Methods: Patients with FG were admitted and enrolled consecutively in this study from March 2008 to April 2020. Statistical analysis was done to evaluate the differences between the two groups and to identify the best cutoff value to predict mortality and the need for intensive care. Read More

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Planned surgery in the COVID-19 pandemic: a prospective cohort study from Nottingham.

Langenbecks Arch Surg 2021 Jun 15. Epub 2021 Jun 15.

Division of Surgery, Nottingham University Hospitals NHS Trust, Nottingham, NG7 2UH, UK.

Purpose: Globally planned surgical procedures have been deferred during the current COVID-19 pandemic. The study aimed to report the outcomes of planned urgent and cancer cases during the current pandemic using a multi-disciplinary prioritisation group.

Methods: A prospective cohort study of patients having urgent or cancer surgery at a NHS Trust from 1st March to 30th April 2020 who had been prioritised by a multi-disciplinary COVID Surgery group. Read More

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COVID-19 in a Subset of Hospitalized Children in Israel.

J Pediatric Infect Dis Soc 2021 Jun 15. Epub 2021 Jun 15.

Infectious Disease and Infection Control Unit, Hillel Yaffe Medical Center, Hadera, Israel.

Background: Most pediatric coronavirus disease 2019 (COVID-19) is mild. We assessed nationally severe COVID-19, including pediatric inflammatory multisystem syndrome (PIMS), in hospitalized children.

Methods: An ongoing, prospective, national surveillance was conducted from March 2020 through March 2021, at 20 hospitals treating children <18 years across Israel (~75% of Israeli hospitals). Read More

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Peer-to-Peer Support and Changes in Health and Well-being in Older Adults Over Time.

JAMA Netw Open 2021 Jun 1;4(6):e2112441. Epub 2021 Jun 1.

Department of Medicine and Population Health, University of Texas at Austin Dell Medical School, Austin.

Importance: Literature on peer-to-peer (P2P) programs suggests they improve health and well-being of older adults. Analysis from a previous study showed P2P to be associated with higher rates of hospitalization and no significant differences in rates of emergency department or urgent care visits; however, it is not known whether measures of health and well-being varied by group over time.

Objective: To compare the association between receiving P2P support and secondary outcomes (ie, health status, quality of life, and depressive and anxiety symptoms) with receiving standard community services (SCS) over time. Read More

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Antibodies to SARS-CoV-2 in All of Us Research Program Participants, January 2-March 18, 2020.

Clin Infect Dis 2021 Jun 15. Epub 2021 Jun 15.

All of Us Research Program, National Institutes of Health, Bethesda, MD.

Background: With limited SARS-CoV-2 testing capacity in the US at the start of the epidemic (January - March), testing was focused on symptomatic patients with a travel history throughout February, obscuring the picture of SARS-CoV-2 seeding and community transmission. We sought to identify individuals with SARS-CoV-2 antibodies in the early weeks of the US epidemic.

Methods: All of Us study participants in all 50 US states provided blood specimens during study visits from January 2 to March 18, 2020. Read More

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Mild to moderate COVID-19 illness in adult outpatients: Characteristics, symptoms, and outcomes in the first 4 weeks of illness.

Medicine (Baltimore) 2021 Jun;100(24):e26371

Division of Infectious Diseases.

Abstract: Most patients with coronavirus disease 2019 (COVID-19) have mild to moderate illness not requiring hospitalization. However, no study has detailed the evolution of symptoms in the first month of illness.At our institution, we conducted remote (telephone and video) visits for all adult outpatients diagnosed with COVID-19 within 24 h of a positive nasopharyngeal polymerase chain test for SARS-CoV-2. Read More

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The epidemic burden on prisons in Lombardy (Italy) during the first wave of the COVID-19 pandemic: the transmission and measures of prevention in detention facilities.

Int J Prison Health 2021 06;ahead-of-print(ahead-of-print)

Welfare General Directorate, Lombardy Regional Health Authority, Milan, Italy.

Purpose: Early on in the COVID-19 pandemic, the scientific community highlighted a potential risk of epidemics occurring inside prisons. Consequently, specific operational guidelines were promptly released, and containment measures were quickly implemented in prisons. This paper aims to describe the spread of COVID-19 in detention facilities within the Lombardy region of Italy during March to July 2020, and the impact of the prevention and control measures implemented. Read More

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Treatment outcomes of erlotinib plus gemcitabine as late-line chemotherapy in unresectable pancreatic cancer.

Jpn J Clin Oncol 2021 Jun 14. Epub 2021 Jun 14.

Department of Hepato-Biliary-Pancreatic Medicine, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.

Objective: With the introduction of modified FOLFIRINOX and gemcitabine plus nab-paclitaxel therapy for unresectable pancreatic cancer, erlotinib plus gemcitabine therapy is now occasionally used as late-line therapy. This study investigates outcomes of treatment with erlotinib plus gemcitabine for unresectable pancreatic cancer.

Methods: We retrospectively analysed consecutive patients with unresectable pancreatic cancer treated with erlotinib plus gemcitabine as the third or later-line chemotherapy between March 2014 and December 2020 in our hospital. Read More

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Diabetic ketoacidosis at presentation of type 1 diabetes in children in Canada during the COVID-19 pandemic.

Paediatr Child Health 2021 Jul 8;26(4):208-209. Epub 2021 Apr 8.

Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.

Type 1 diabetes is a common chronic illness in childhood. Diabetic ketoacidosis (DKA) is the leading cause of morbidity and mortality in children with type 1 diabetes. Early recognition of symptoms of diabetes and immediate initiation of treatment are important factors in preventing DKA at first presentation. Read More

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Adherence to preventive behaviors among college students during COVID-19 pandemic in China: The role of health beliefs and COVID-19 stressors.

Curr Psychol 2021 Jun 9:1-11. Epub 2021 Jun 9.

Institute of Developmental Psychology, Beijing Normal University, Beijing, People's Republic of China.

Before herd immunity is reached, preventive practices still play an important role in controlling the COVID-19 pandemic. Adherence to preventive behaviors could be determined by individuals' health beliefs, which would be influenced by antecedent factors such as previous exposure to pandemic stressors. Applying the health belief model (HBM), this study aims to examine the mediation association among COVID-19 stressors, HBM constructs, and preventive behaviors. Read More

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Impact of covid-19 pandemic on characteristics of dental emergencies and treatment services at tertiary care centre.

Saudi Dent J 2021 Jun 6. Epub 2021 Jun 6.

Department of Oral Health Science Centre, PGIMER, Chandigarh 12, India.

To categorize and compare the dental emergencies along with status of health services received in the tertiary dental health care centre during the pre covid- 19 periods and period of the complete lockdown in COVID 19 pandemic. Methods: A retrospective cross-sectional observational survey was conducted. Four different groups period were studied on patients who visited for dental emergencies at tertiary care centre. Read More

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A multi-method approach to modeling COVID-19 disease dynamics in the United States.

Sci Rep 2021 Jun 14;11(1):12426. Epub 2021 Jun 14.

Booz Allen Hamilton, 4747 Bethesda Ave., Bethesda, MD, 20814, USA.

In this paper, we proposed a multi-method modeling approach to community-level spreading of COVID-19 disease. Our methodology was composed of interconnected age-stratified system dynamics models in an agent-based modeling framework that allowed for a granular examination of the scale and severity of disease spread, including metrics such as infection cases, deaths, hospitalizations, and ICU usage. Model parameters were calibrated using an optimization technique with an objective function to minimize error associated with the cumulative cases of COVID-19 during a training period between March 15 and October 31, 2020. Read More

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Cross sectional study of the clinical characteristics of French primary care patients with COVID-19.

Sci Rep 2021 Jun 14;11(1):12492. Epub 2021 Jun 14.

Primary Care Unit, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

The early identification of patients suffering from SARS-CoV-2 infection in primary care is of outmost importance in the current pandemic. The objective of this study was to describe the clinical characteristics of primary care patients who tested positive for SARS-CoV-2. We conducted a cross-sectional study between March 24 and May 7, 2020, involving consecutive patients undergoing RT-PCR testing in two community-based laboratories in Lyon (France) for a suspicion of COVID-19. Read More

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Role of meteorological factors in the transmission of SARS-CoV-2 in the United States.

Nat Commun 2021 06 14;12(1):3602. Epub 2021 Jun 14.

Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, USA.

Improved understanding of the effects of meteorological conditions on the transmission of SARS-CoV-2, the causative agent for COVID-19 disease, is needed. Here, we estimate the relationship between air temperature, specific humidity, and ultraviolet radiation and SARS-CoV-2 transmission in 2669 U.S. Read More

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Away Rotations at Integrated Thoracic Surgery Programs: Applicant and Program Director Perspectives.

J Surg Educ 2021 Jun 11. Epub 2021 Jun 11.

Department of Surgery, Division of Cardiothoracic Surgery, Chapel Hill, North Carolina. Electronic address:

Objective: Integrated thoracic surgery residency program (IP) applicants often complete away rotations to stand out from the objective standard criteria. Little is known about the perceptions of these rotations. We aimed to examine the perceptions of value, cost, and expectations of away rotations among IP applicants and program directors. Read More

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Changes in the ambulatory care of prostate cancer patients during the SARS-CoV-2 pandemic. Literature review and contribution of our group in telematic care.

Actas Urol Esp 2021 Apr 30. Epub 2021 Apr 30.

Servicio de Urología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.

Introduction And Objective: The COVID-19 pandemic has brought about changes in the management of urology patients, especially those with prostate cancer. The aim of this work is to show the changes in the ambulatory care practices by individualized telematic care for each patient profile.

Materials And Methods: Articles published from March 2020 to January 2021 were reviewed. Read More

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The Epidemiology and Effectiveness of Synchronized Cardioversion in a UK Prehospital Setting: A Retrospective Cross-Sectional Study.

Prehosp Disaster Med 2021 Jun 15:1-5. Epub 2021 Jun 15.

South East Coast Ambulance Service NHS Foundation Trust, Crawley, United Kingdom of Great Britain and Northern Ireland.

Background: Synchronized cardioversion is an internationally accepted standard therapy for unstable tachyarrhythmias, but it is conventionally an in-hospital physician-led intervention. Increasingly, it is being brought forward into the prehospital setting as part of a specialist paramedic scope of practice; however, very little literature exists regarding the epidemiology or efficacy in this setting.

Methods: All patients receiving cardioversion within a United Kingdom (UK) ambulance service were identified using an electronic database. Read More

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