9 results match your criteria manner biofabricated

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Multiplexing physical stimulation on single human induced pluripotent stem cell-derived cardiomyocytes for phenotype modulation.

Biofabrication 2021 Mar 12;13(2):025004. Epub 2021 Mar 12.

Department of Materials, Imperial College London, London, United Kingdom. Department of Bioengineering, Imperial College London, London, United Kingdom. Institute of Biomedical Engineering, Imperial College London, London, United Kingdom. National Heart and Lung Institute, Imperial College London, London, United Kingdom.

Traditional in vitro bioengineering approaches whereby only individual biophysical cues are manipulated at any one time are highly inefficient, falling short when recapitulating the complexity of the cardiac environment. Multiple biophysical cues are present in the native myocardial niche and are essential during development, as well as in maintenance of adult cardiomyocyte (CM) phenotype in both health and disease. This study establishes a novel biofabrication workflow to study and manipulate hiPSC-CMs and to understand how these cells respond to a multiplexed biophysical environment, namely 3D shape and substrate stiffness, at a single cell level. Read More

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Remediation of emerging environmental pollutants: A review based on advances in the uses of eco-friendly biofabricated nanomaterials.

Chemosphere 2021 Jul 15;275:129975. Epub 2021 Feb 15.

Laboratory of Plant Healthcare and Diagnostics, PG Department of Biotechnology and Microbiology, Karnataka University, Dharwad, 580 003, Karnataka, India. Electronic address:

The increased environmental pollutants due to anthropogenic activities are posing an adverse effects and threat on various biotic forms on the planet. Heavy metals and certain organic pollutants by their toxic persistence in the environment are regarded as significant pollutants worldwide. In recent years, pollutants exist in various forms in the environment are difficult to eliminate by traditional technologies due to various drawbacks. Read More

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Biofabricated Fatty Acids-Capped Silver Nanoparticles as Potential Antibacterial, Antifungal, Antibiofilm and Anticancer Agents.

Pharmaceuticals (Basel) 2021 Feb 9;14(2). Epub 2021 Feb 9.

Department of Stem Cell Biology, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.

The current study demonstrates the synthesis of fatty acids (FAs) capped silver nanoparticles (AgNPs) using aqueous poly-herbal drug Liv52 extract (PLE) as a reducing, dispersing and stabilizing agent. The NPs were characterized by various techniques and used to investigate their potent antibacterial, antibiofilm, antifungal and anticancer activities. GC-MS analysis of PLE shows a total of 37 peaks for a variety of bio-actives compounds. Read More

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February 2021

Biofabrication of cell-laden allografts of goat urinary bladder scaffold for organ reconstruction/regeneration.

Tissue Cell 2020 Dec 28;67:101443. Epub 2020 Sep 28.

Central Laboratory for Stem Cell Research and Translational Medicine, Centre for Liver Research and Diagnostics, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad 500058, Telangana, India. Electronic address:

Introduction: Bladder dysfunction has been considered as one of the most critical health conditions with no proper treatment. Current therapeutic approaches including enterocystoplasty have several limitations. Hence, biofabrication of cell-laden biological allografts using decellularized Goat urinary bladder scaffolds for organ reconstruction/regeneration was major objective of this study. Read More

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December 2020

Madhuca longifolia embedded silver nanoparticles attenuates diethylnitrosamine (DEN) -induced renal cancer via regulating oxidative stress.

Curr Drug Deliv 2020 Sep 10. Epub 2020 Sep 10.

Department of Pharmaceutical Sciences, Faculty of Health Sciences, Sam Higginbottom University of Agriculture, Technology & Sciences, Allahabad -211007, Uttar Pradesh. India.

Objective: Madhuca longifolia has been used for the treatment of renal cancer. Therefore, the current study describes the protective effects of biofabricated silver nanoparticles (MLAgNPs) using Madhuca longifolia aqueous leaves extract against diethylnitrosamine (DEN) induced renal cell carcinoma (RCC) in rats.

Methods: Animals were categorized into five groups and treated with doses of silver nanoparticles for 16 weeks. Read More

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September 2020

Larvicidal and pupicidal evaluation of silver nanoparticles synthesized using Aquilaria sinensis and Pogostemon cablin essential oils against dengue and zika viruses vector Aedes albopictus mosquito and its histopathological analysis.

Artif Cells Nanomed Biotechnol 2018 Sep 31;46(6):1171-1179. Epub 2017 Aug 31.

a Ministry of Agriculture Key Laboratory of Agricultural Entomology , Institute of Insect Sciences, Zhejiang University , Hangzhou , Zhejiang , PR China.

Mosquitoes pose a threat to humans and animals, causing millions of deaths every year. Vector control by effective eco-friendly pesticides of natural origin is a serious issue that requires urgent attention. The employment of green-reducing extracts for nanoparticles biosynthesis in a rapid and single-step process represents a promising strategy. Read More

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September 2018

Incorporating LsrK AI-2 quorum quenching capability in a functionalized biopolymer capsule.

Biotechnol Bioeng 2018 02 16;115(2):278-289. Epub 2017 Oct 16.

Institute for Bioscience and Biotechnology Research (IBBR), University of Maryland, College Park, Maryland.

Antibacterial resistance is an issue of increasing severity as current antibiotics are losing their effectiveness and fewer antibiotics are being developed. New methods for combating bacterial virulence are required. Modulating molecular communication among bacteria can alter phenotype, including attachment to epithelia, biofilm formation, and even toxin production. Read More

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February 2018

Bioremediation potential of arsenic by non-enzymatically biofabricated silver nanoparticles adhered to the mesoporous carbonized fungal cell surface of Aspergillus foetidus MTCC8876.

J Environ Manage 2017 Oct 12;201:435-446. Epub 2017 Jul 12.

Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, 741235, India. Electronic address:

Our study aiming for the diminution of arsenic concentration in arsenic contaminated aqua environment by using novel adsorbents based on bio-fabricated silver nanoparticles on a fungal cell surface. Bioreduction of silver ion was done in a non-enzymatic manner in presence of the biomass of fungus Aspergillus foetidus MTCC8876. Aspergillus spp. Read More

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October 2017

Controlled Positioning of Cells in Biomaterials-Approaches Towards 3D Tissue Printing.

J Funct Biomater 2011 Aug 4;2(3):119-54. Epub 2011 Aug 4.

Institute for Biomechanics, ETH Zurich, 8093 Zurich, Switzerland.

Current tissue engineering techniques have various drawbacks: they often incorporate uncontrolled and imprecise scaffold geometries, whereas the current conventional cell seeding techniques result mostly in random cell placement rather than uniform cell distribution. For the successful reconstruction of deficient tissue, new material engineering approaches have to be considered to overcome current limitations. An emerging method to produce complex biological products including cells or extracellular matrices in a controlled manner is a process called bioprinting or biofabrication, which effectively uses principles of rapid prototyping combined with cell-loaded biomaterials, typically hydrogels. Read More

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