82 results match your criteria man hyperpyrexia


The clinical characteristics and outcomes of patients with fever of unknown origin caused by parasitic infection.

Medicine (Baltimore) 2021 Apr;100(16):e25538

Department of General Internal Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Abstract: There are over 200 causes of fever of unknown origin (FUO), and although parasitic infection is an increasingly uncommon cause, a definitive diagnosis remains important to ensure rapid treatment and to prevent adverse sequelae through delay. Here, we studied the clinical features and outcomes of patients admitted with FUO and diagnosed with parasitic infection to improve our understanding of the features of parasitic FUO.Medical records of patients admitted to Peking Union Medical College Hospital between 2013 and 2019 with FUO and diagnosed with parasitic infection were reviewed. Read More

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SARS-CoV-2 associated viral encephalitis with mortality outcome.

Interdiscip Neurosurg 2021 Sep 25;25:101132. Epub 2021 Feb 25.

Department of Neurosurgery, Medical University of South Carolina, Charleston, USA.

Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) appeared in Wuhan, China, in December 2019; apart from common conditions such as cough, fever, and severe respiratory complications, difficulty in breathing, including tachypnea, new studies on neurological manifestations have gained public interest.

Case Report: An 89-year-old man was admitted to the neurocritical care department in a specialized hospital with headache, dizziness, hyperpyrexia, myalgia, rash, and tremors. MRI showed viral encephalitis near to basal ganglia and thalami. Read More

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September 2021

Subcortical Structure Disruption in Diffusion Tensor Tractography of the Patient With the Syndrome of Irreversible Lithium-Effectuated Neurotoxicity Combined With Neuroleptic Malignant Syndrome: A Case Report.

Clin Neuropharmacol 2021 Mar-Apr 01;44(2):62-67

Department of Physical Medicine and Rehabilitation, National Health Insurance Service Ilsan Hospital, Ilsan, Republic of Korea.

Background: Lithium can cause not only acute neurotoxicity but also chronic and persistent neurotoxicity known as syndrome of irreversible lithium-effectuated neurotoxicity (SILENT). The combined use of lithium and antipsychotics increases the possibility of SILENT. Neuroleptic malignant syndrome (NMS) is a reversible, idiosyncratic, and potentially life-threatening reaction, which is usually caused by antipsychotics and other agents, such as mood stabilizers (eg, lithium and metoclopramide). Read More

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February 2021

Beneficial effects of dantrolene in the treatment of rhabdomyolysis as a potential late complication associated with COVID-19: a case report.

Eur J Med Res 2021 Feb 8;26(1):18. Epub 2021 Feb 8.

Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamimachi, Itabashi-Ku, Tokyo, 173-8610, Japan.

Background: Patients with severe COVID-19 have disorders of the respiratory, cardiovascular, coagulation, skeletal muscle, and central nervous systems. These systemic failures may be associated with cytokine release syndrome, characterized by hyperpyrexia, thrombocytopenia, hyperferritinemia, and the elevation of other inflammatory markers. Rhabdomyolysis with high fever is a complication that is rarely found in COVID-19. Read More

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February 2021

A man in his fifties with increasing motor fluctuations, sleep impairment and altered mental status.

Tidsskr Nor Laegeforen 2020 10 8;140(14). Epub 2020 Oct 8.

Background/case Presentation: A man in his fifties with advanced Parkinson´s disease was admitted with increasing motor fluctuations including dyskinesias, as well as hallucinations and delusions. After reduction of oral dopaminergic treatment, the dyskinesias improved, but the psychotic symptoms persisted. They were perceived as levodopa-induced, despite concurrent prominent bradykinetic-rigid symptoms. Read More

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October 2020

Protracted hyperthermia and delayed rhabdomyolysis in ecstasy toxicity: A case report.

Medicine (Baltimore) 2020 Oct;99(41):e21842

University of Hawai'i at Mānoa, John A. Burns School of Medicine, Honolulu, HI.

Rationale: Despite toxicity and unpredictable adverse effects, ecstasy use has increased in the United States. Onset of hyperpyrexia, rhabdomyolysis, disseminated intravascular coagulation (DIC), among other symptoms, occurs within hours of ingestion. Moreover, patients who experience hyperpyrexia, altered mental status, DIC, and multiorgan failure, rarely survive. Read More

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October 2020

Neuroleptic Malignant Syndrome: A Potential Etiology of Multisystem Organ Failure in a Burn Patient.

Am Surg 2020 Sep 28:3134820945245. Epub 2020 Sep 28.

Division of Trauma & Acute Care Surgery, Department of Surgery, University of South Alabama, Mobile, AL, USA.

Neuroleptic malignant syndrome (NMS) is described in the medical literature but rarely seen among acutely ill trauma patients. A 44-year-old man with burns to the hands and back after a chemical explosion was transported to an outside facility where he received treatment for presumed acute coronary syndrome after developing ventricular tachycardia and elevated serum troponins after the exposure. His cardiac catheterization was unremarkable, but an echocardiogram revealed severe cardiomyopathy, and he was also in multisystem organ failure. Read More

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September 2020

The metagenomic next-generation sequencing in diagnosing central nervous system angiostrongyliasis: a case report.

BMC Infect Dis 2020 Sep 21;20(1):691. Epub 2020 Sep 21.

Department of Neurology, National Key Clinical Department and Key Discipline of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Backgrounds: The incidence of angiostrongyliasis is increasing in recent decades due to the expanding endemic areas all over the world. Clinicians face tremendous challenge of diagnosing angiostrongyliasis because of the lack of awareness of the disease and less effective definitive laboratory tests.

Case Presentation: A 27-year-old man initially manifested skin itching, emesis, myalgia and quadriparesis. Read More

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September 2020

Delta brush variant: A novel ictal EEG pattern in anti-NMDAR encephalitis.

Epilepsia Open 2020 Sep 12;5(3):507-513. Epub 2020 Aug 12.

Department of Neurology First Affiliated Hospital Guangxi Medical University Nanning China.

Seizure is one of the main symptoms of anti-NMDAR encephalitis, but data of ictal electroencephalogram (EEG) patterns remain limited. In this study, we aimed to introduce a unique ictal pattern. This delta brush variant (DBV) was characterized as generalized delta rhythm with fast spike activity riding on it. Read More

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September 2020

Use of the CytoSorb adsorption device in MDMA intoxication: a first-in-man application and in vitro study.

Intensive Care Med Exp 2020 Jun 15;8(1):21. Epub 2020 Jun 15.

Department of Cardiology and Angiology I, Faculty of Medicine, Heart Center Freiburg University, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

Background: 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") abuse is frequent, and overdosing might cause severe and eventually lethal multi-organ failure. To date, there is no causal therapy of MDMA intoxication and removal of MDMA from the circulation might be a reasonable measure to prevent adverse courses after overdosing. We present here first-in-man experience and in vitro data supporting a potential role of an adsorber device in severe MDMA overdosing. Read More

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Acute Flaccid Paralysis as the Initial Manifestation of Japanese Encephalitis: a Case Report.

Jpn J Infect Dis 2020 Sep 30;73(5):381-382. Epub 2020 Apr 30.

The Department of Neurology, West China Hospital, Sichuan University, China.

Japanese encephalitis (JE) is a clinical disease caused by inflammation of the central nervous system. The symptoms of this disease range broadly in severity from mild febrile illness to acute meningomyeloencephalitis. JE has been associated with a variety of neurological abnormalities, such as altered sensorium, seizures, focal neurological deficit, and acute flaccid paralysis (AFP). Read More

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September 2020

Concomitant severe influenza and cryptococcal infections: A case report and literature review.

Medicine (Baltimore) 2019 May;98(19):e15544

Department of Respiratory and Critical Care Medicine.

Concomitant influenza and cryptococcal infections are rare. Herein, we describe an unusual case of an avian influenza A (H7N9) infection with several severe mixed bacterial infections and systemic super-infection with Cryptococcus neoformans presenting as ventilator-associated pneumonia (VAP) and bloodstream infection in a previously immunocompetent man during hospitalization.A 58-year-old man was admitted to our hospital complaining of hyperpyrexia, dyspnoea, cough, and phlegm with blood. Read More

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Hem-o-lok clip found in the common bile duct 3 years after laparoscopic cholecystectomy and surgical exploration.

J Int Med Res 2019 Feb 7;47(2):1052-1058. Epub 2019 Jan 7.

1 Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.

Endoscopic retrograde cholangiopancreatography (ERCP) with stone extraction is a common and preferred choice for gallstone disease. Laparoscopic common bile duct exploration (LCBDE) and laparoscopic cholecystectomy (LC) are being increasingly used for managing choledocholithiasis and cholecystolithiasis. We report a case of a Hem-o-lok clip that was dropped into the common bile duct (CBD) after LC and surgical common bile duct exploration (CBDE). Read More

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February 2019

T. marneffei infection complications in an HIV-negative patient with pre-existing pulmonary sarcoidosis: a rare case report.

BMC Infect Dis 2018 08 10;18(1):390. Epub 2018 Aug 10.

Division of Pulmonary Medicine, the People's Hospital of Cangnan, Wenzhou Medical University, No.2288, Yucang Road, Cangnan County, Zhejiang, 325800, China.

Background: Talaromyces marneffei (T. marneffei) is a thermal dimorphic pathogenic fungus that often causes fatal opportunistic infections in human immunodeficiency virus (HIV)-infected patients. Although T. Read More

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Undetectable high-density lipoprotein cholesterol in acute malaria.

J Clin Lipidol 2018 May - Jun;12(3):822-825. Epub 2018 Mar 9.

Guy's, St Thomas' and Lewisham and Greenwich Trust, St. Thomas' Hospital, London, United Kingdom.

We report the case of a 39-year-old West African man in whom high-density lipoprotein cholesterol (HDL-C) was identified as undetectable at <0.08 mmol/L. Total cholesterol in the same sample was 2. Read More

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September 2019

Significance of monitoring plasma concentration of voriconazole in a patient with liver failure: A case report.

Medicine (Baltimore) 2017 Oct;96(42):e8039

Liver Failure Treatment and Research Center, 302 Hospital of PLA, Xisihuanzhonglu, Beijing, China.

Rationale: Invasive pulmonary aspergillosis is associated with significant morbidity and mortality in patients with liver failure. Voriconazole (VRCZ) is recommended as a primary therapeutic agent for the treatment of invasive aspergillosis and metabolized in the liver. Now, data are still lacking on the safety and appropriate dosage of VRCZ in patients with liver failure. Read More

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October 2017

Anti-N-methyl-D-aspartate receptor encephalitis that aggravates after acinetobacter baumannii pneumonia: A case report.

World J Clin Cases 2017 Sep;5(9):368-372

Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.

We report an atypical case of anti-N-methyl-D-aspartate receptor encephalitis (ANMDARE). A 27-year-old man diagnosed with ANMDARE received immunotherapy and had a good recovery. However, within one month, he developed severe status epilepticus and decreased level of conscience with new hyperpyrexia and dyspnea, and was admitted to the emergency intensive care unit. Read More

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September 2017

Preserving brain function in a comatose patient with septic hyperpyrexia (41.6 °C): a case report.

J Med Case Rep 2017 Feb 13;11(1):40. Epub 2017 Feb 13.

Department of Internal Medicine, Larkin Community Hospital, Graduate Medical Education, 7000 SW 62nd Avenue, Suite 401, South Miami, FL, 33142, USA.

Background: Pyrexia is a physiological response through which the immune system responds to infectious processes. Hyperpyrexia is known to be neurodegenerative leading to brain damage. Some of the neurotoxic effects of hyperpyrexia on the brain include seizures, decreased cognitive speed, mental status changes, coma, and even death. Read More

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February 2017

Whether to Proceed With Deep Brain Stimulator Battery Change in a Patient With Signs of Potential Sepsis and Parkinson Hyperpyrexia Syndrome: A Case Report.

A A Case Rep 2017 Apr;8(8):187-191

From the Departments of *Anesthesiology; †Neurosurgery; and ‡Pediatrics, Albany Medical Center, Albany, New York.

Parkinsonism-hyperpyrexia syndrome (PHS) is a neurologic emergency associated with anti- Parkinson medication withdrawal; however, its clinical presentation mimics sepsis. We describe the case of a 69-year-old man with advanced Parkinson disease who presented for exchange of the depleted battery in his subthalamic deep brain stimulator. The patient's preoperative symptoms of fever, rigidity, altered consciousness, and autonomic instability presented a dilemma whether to proceed with battery exchange to treat PHS or postpone surgery due to potential sepsis. Read More

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Acute Vertebrobasilar Territory Infarcts due to Heat Stroke.

J Stroke Cerebrovasc Dis 2015 Jun 16;24(6):e135-8. Epub 2015 Apr 16.

Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, India.

Heat stroke is common in tropical country like India especially during the summer season. We report an unusual case of acute vertebrobasilar territory infarcts due to heat stroke. A middle-aged man developed hyperpyrexia (42. Read More

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[Clinical characteristics and early effective treatment for pulmonary infection after acute cervical spinal cord injury].

Zhonghua Yi Xue Za Zhi 2013 Jan;93(5):352-6

Department of Orthopedics, Changzheng Hospital, Shanghai, China.

Objective: To explore the clinical characteristics and early effective treatment for pulmonary infection after acute cervical spinal cord injury.

Methods: A total of 215 inpatients with acute cervical spinal cord injury were retrospectively analyzed. Their chest radiological films and blood profiles at discharge were analyzed. Read More

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January 2013

A primary pulmonary glomus tumor complicated with hyperpyrexia and anemia.

Ann Thorac Surg 2013 Feb;95(2):e29-31

Department of Thoracic Surgery, Peking University People's Hospital, Beijing, PR China.

Pulmonary glomus tumors are extremely rare, with only 19 cases having been reported worldwide. The glomus body is considered to be related to the regulation of body temperature, but the reported cases were not associated with hyperpyrexia. Here, we describe a 28-year-old man with hyperpyrexia and anemia complicated with a coin lesion of the right lung. Read More

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February 2013

Amelanocytic anhidrotic alopecia areata-like phenotype after allogeneic hematopoietic cell transplant.

Arch Dermatol 2012 Aug;148(8):931-4

Section of Dermatology, Department of Medicine, The University of Chicago, Chicago, Illinois 60637, USA.

Background: Diffuse alopecia areata or canities subita is a rare variant of alopecia in which hair loss is associated with regrowth of white hairs and possible lightening of the skin. Preferential loss of pigmented hair in this disorder may be related to the melanin pigment system and/or melanocytes. Acquired generalized anhidrosis can be associated with autoimmune disease, cancer, graft-vs-host disease, or medications or can be idiopathic. Read More

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Intrathecal gene therapy for treatment of leptomeningeal carcinomatosis.

J Neurooncol 2011 Aug 26;104(1):365-9. Epub 2010 Nov 26.

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive, 10-3D20, MSC-1414, Bethesda, MD 20892-1414, USA.

Leptomeningeal carcinomatosis occurs occasionally in patients with solid malignancies and carries a poor prognosis despite treatment with systemic chemotherapy and/or radiotherapy. We describe the case of a 43 year old man who presented with leptomeningeal carcinomatosis secondary to malignant melanoma. The patient received intraventricular delivery of NIH3T3 producer cells expressing the thymidine kinase (HSV-Tk1) gene via a retroviral vector followed by intravenous ganciclovir. Read More

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[Patient with encephalitis presenting with olanzapine-responsive malignant catatonia].

Rinsho Shinkeigaku 2010 May;50(5):329-31

Department of Neurology, Shibata Hospital-Niigata Preferctural Hospital.

We report the case of a 29-year-old man, who could not remember some words of Kanji and showed emotional instability. Magnetic resonance imaging (MRI) scan of his brain appeared normal. Cerebrospinal fluid (CSF) analysis showed lymphocytic pleocytosis. Read More

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[Bromo-Dragonfly poisoning of 18-year-old male].

Ugeskr Laeger 2010 May;172(19):1461-2

Bispebjerg Hospital, Anaestesi- og Operationsafdeling/Giftlinjen, Denmark.

Bromo-Dragonfly (BDF) is a designer drug chemically related to LSD and amphetamine. The first registration in Denmark was in October 2007. In the present case an 18-year-old man ingested about 2 ml BDF and developed acute psychosis. Read More

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[The Mirizzi syndrome. Analysis of an unknown complication of the gallstones].

Ann Ital Chir 2007 Sep-Oct;78(5):419-25

Università degli Studi di Parma, Scuola di Medicina, Dipartimento di Scienze Chirurgiche, Chirurgia Generale e Trapianti di Organi, Parma, Italy.

Background: Mirizzi syndrome is one possible complication of the gallstones. The incidence in patients treated with cholecystectomy is 0.7-1. Read More

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The excitatory:inhibitory ratio model (EIR model): An integrative explanation of acute autonomic overactivity syndromes.

Authors:
Ian J Baguley

Med Hypotheses 2008 20;70(1):26-35. Epub 2007 Jun 20.

Brain Injury Rehabilitation Service, Westmead Hospital, P.O. Box 533, Westmead, Wentworthville, NSW 2145, Australia.

Numerous medical conditions present with acute and severe autonomic and muscular overactivity. These syndromes include Neuroleptic Malignant Syndrome, Serotonin Syndrome, Dysautonomia (or paroxysmal sympathetic storms) following acquired brain injury, Autonomic Dysreflexia, Parkinsonian-Hyperpyrexia Syndrome, Malignant Catatonia, intrathecal baclofen withdrawal, Malignant Hyperthermia, Stiff Man Syndrome and Irukandji Syndrome. In their worst forms, each of these syndromes are relatively rare, are treated by different medical specialties and show widely varying pathophysiology. Read More

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Indeterminate cell histiocytosis in association with later occurrence of acute myeloblastic leukaemia.

Br J Dermatol 2007 Jun 25;156(6):1357-61. Epub 2007 Apr 25.

Hematology I, Bone Marrow Transplant Unit, Policlinico IRCCS Hospital, Mangiagalli and Regina Elena Foundation, University of Milan, Milan, Italy.

Indeterminate cell histiocytosis (ICH) is a proliferation of indeterminate CD1a+, CD68+, S100+ and CD207- dermal dendritic cells. We describe a 39-year-old man who developed diffuse ICH and, 6 years later, acute myeloblastic leukaemia (AML). He was treated with cyclophosphamide, etoposide and vinblastine until 2003. Read More

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Steroid-responsive encephalitis lethargica syndrome with malignant catatonia.

Intern Med 2007 15;46(6):307-10. Epub 2007 Mar 15.

Department of Neurology, National Hospital Organization Okayama Medical Center.

We report a 47-year-old man who is considered to have sporadic encephalitis lethargica (EL). He presented with hyperpyrexia, lethargy, akinetic mutism, and posture of decorticate rigidity following coma and respiratory failure. Intravenous methylprednisolone pulse therapy improved his condition rapidly and remarkably. Read More

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