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Cecal bascule - An unusual cause of intestinal obstruction: A case report.

Int J Surg Case Rep 2021 Apr 14;82:105888. Epub 2021 Apr 14.

Department of General Surgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan. Electronic address:

Introduction: Cecal bascule is a rare type of cecal volvulus occurring in the elderly population with a male predominance. It is a condition where the cecum folds upward upon itself.

Importance: There are only a handful of case reports published about cecal bascule. Read More

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Mothers as perpetrators and bystanders of child sexual abuse.

Child Abuse Negl 2021 Apr 17;117:105068. Epub 2021 Apr 17.

Department of Child and Adolescent Psychiatry/Psychotherapy, University Hospital Ulm, Germany; Center for Child Protection in Medicine in Baden-Württemberg, Germany.

Background: In research and literature, little attention has been paid to the role of women, especially mothers, in child sexual abuse.

Objective: In order to estimate prevalences on mothers as perpetrators and bystanders, data was collected in a German nationwide representative survey.

Participants And Setting: A total of 2,531 participants (53. Read More

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Adverse childhood experiences in New Zealand and subsequent victimization in adulthood: Findings from a population-based study.

Child Abuse Negl 2021 Apr 17;117:105067. Epub 2021 Apr 17.

School of Māori Studies and School of Pacific Studies, Faculty of Arts, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. Electronic address:

Background: Adverse childhood experiences (ACEs) are widespread and are associated with adverse outcomes in later life, yet few studies have explored their prevalence and consequences in New Zealand.

Objectives: To provide prevalence estimates of ACEs in New Zealand using a large sample of adults, and to explore the associations between ACEs and experience of violence by intimate partners and non-partners in adulthood.

Participants And Setting: 2,887 participants (1464 female, 1423 male) from the 2019 New Zealand Family Violence Survey, a population based study conducted in New Zealand between March 2017-March 2019. Read More

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Evaluation of Promega PowerSeq™ Auto/Y systems prototype on an admixed sample of Rio de Janeiro, Brazil: Population data, sensitivity, stutter and mixture studies.

Forensic Sci Int Genet 2021 Apr 6;53:102516. Epub 2021 Apr 6.

Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:

Forensic DNA typing typically relies on the length-based (LB) separation of PCR products containing short tandem repeat loci (STRs). Massively parallel sequencing (MPS) elucidates an additional level of STR motif and flanking region variation. Also, MPS enables simultaneous analysis of different marker-types - autosomal STRs, SNPs for lineage and identification purposes, reducing both the amount of sample used and the turn-around-time of analysis. Read More

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Oxytocin and 'social hyperthermia': Interaction with β-adrenergic receptor-mediated thermogenesis and significance for the expression of social behavior in male and female mice.

Horm Behav 2021 Apr 17;131:104981. Epub 2021 Apr 17.

Division of Science, Indiana University-Purdue University, Columbus, Columbus, IN, United States of America.

Oxytocin (OT) is a critical regulator of multiple facets of energy homeostasis, including brown adipose tissue (BAT) thermogenesis. Nevertheless, it is unclear what, if any, consequence the thermoregulatory and metabolic effects of OT have for the display of social behavior in adult rodents. Here, we examine the contribution of the OT receptor (OTR) and β adrenergic receptor (βAR) to the increase in body temperature that typically accompanies social interaction (i. Read More

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Independent and combined associations of urinary heavy metals exposure and serum sex hormones among adults in NHANES 2013-2016.

Environ Pollut 2021 Apr 8;281:117097. Epub 2021 Apr 8.

State Key Laboratory of Reproductive Medicine, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, 211166, China. Electronic address:

Accumulating evidences indicated that heavy metals may disrupt human sex hormones. However, the combined effects of heavy metals on sex hormones remain to be clarified. To explore the independent and combined associations between heavy metal exposure and serum sex hormones among adults, data of 2728 adults from the National Health and Nutrition Examination Survey (NHANES) was applied. Read More

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The importance of clinical and radiological findings for the definitive histopathologic diagnosis of benign fibro-osseous lesions of the jaws: Study of 276 cases.

J Stomatol Oral Maxillofac Surg 2021 Apr 17. Epub 2021 Apr 17.

Istanbul University, Institute of Oncology, Department of Tumour Pathology, Istanbul, Turkey.

Purpose: Benign fibro-osseous lesions (BFOLs) are heterogeneous intraosseous dis- ease processes sharing overlapping histopathologic features and demonstrate a wide range of biological behavior. The aim of this study is to highlight the importance of clinical and radiological findings for the definitive histopathologic diagnosis of benign fibro-osseous lesions of the jaws.

Materials And Methods: This is a cross-sectional retrospective study evaluating the three main groups of BFOLs: Cemento-osseous dysplasia, ossifying fibroma, and fibrous dysplasia. Read More

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The bullies are the leaders of the next generation: inherited aminergic neurotransmitter system changes in socially dominant zebrafish, Danio rerio.

Behav Brain Res 2021 Apr 17:113309. Epub 2021 Apr 17.

Department of Anatomy, POB 63, 00014, University of Helsinki, Helsinki, Finland.

We studied the social hierarchy in zebrafish and assessed differences in neurotransmitters and behavior in the F1 generation offspring of dominant and subordinate zebrafish (Danio rerio). We used behavioral assays to study locomotion, ability to complete cognitive tasks, social interaction and aggression. To study the neurochemical changes, we applied quantitative polymerase chain reaction, high pressure liquid chromatography and immunohistochemistry. Read More

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Mechanisms of Doxorubicin-Mediated Reproductive Toxicity - A Review.

Reprod Toxicol 2021 Apr 17. Epub 2021 Apr 17.

Centre for Cardiovascular and Adverse Drug Reactions, Department of Biotechnology, School of Bio and Chemical Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, PIN 626126, India. Electronic address:

The anticancer drug Doxorubicin has been associated with several adverse side-effects including reproductive toxicity in both genders. The current review has complied the mechanisms of doxorubicin induced reproductive toxicity. The articles cited in the review were searched using Google Scholar, PubMed, Scopus, Science Direct. Read More

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Bioaccumulation of phenolic endocrine disruptors in the clam Rangia cuneata: storage in shells and influence of size and sex.

Environ Res 2021 Apr 17:111181. Epub 2021 Apr 17.

University of Gdansk, Institute of Oceanography, Department of Marine Chemistry and Environmental Protection, Al. Marszałka Piłsudskiego 46, 81-378 Gdynia, Poland.

This study aimed to investigate the sequestration of phenolic endocrine disrupting compounds (EDCs) such as bisphenol A (BPA), 4-t-octylphenol (4-t-OP), and 4-nonylphenol (4-NP) in the shells of the mature clam Rangia cuneata from the Vistula Lagoon (southern Baltic Sea) and to determine the influence of sex and shell length on bioaccumulation of these contaminants. Even though there is broad interest in EDCs influences on aquatic organisms, these basic parameters are poorly understood, yet necessary for assessing environmental risks for clams. Average proportions of the total body burden (ng/individual) deposited in shells of R. Read More

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Right-to-left shunt detection using transforaminal insonation of the basilar artery.

J Neuroimaging 2021 Apr 20. Epub 2021 Apr 20.

Department of Neurology, Mayo Clinic College of Medicine and Science, Scottsdale, Arizona, USA.

Background And Purpose: Investigation for patent foramen ovale (PFO) is warranted in patients with cryptogenic stroke (CS), as PFO closure is recommended in select CS patients for secondary stroke prevention. Transcranial Doppler (TCD) is noninvasive and has high sensitivity for PFO screening. However, 10% of the population has insufficient temporal bone windows to perform standard TCD monitoring of the middle cerebral arteries (MCAs). Read More

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Sperm adaptation in relation to salinity in three goby species.

J Fish Biol 2021 Apr 20. Epub 2021 Apr 20.

Centre for Marine Evolutionary Biology, University of Gothenburg, Gothenburg, Sweden.

In externally fertilizing species the gametes of both males and females are exposed to the influences of the environment into which they are released. Sperm are sensitive to abiotic factors such as salinity, but they are also affected by biotic factors such as sperm competition. Here we compared the performance of sperm of three goby species, the painted goby, Pomatoschistus pictus, the two-spotted goby, P. Read More

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Functional Dyspepsia, Peptic Ulcer, and Helicobacter pylori Infection in a Rural Community of South Asia: An Endoscopy-Assisted Household Survey.

Clin Transl Gastroenterol 2021 Apr 16;12(4):e00334. Epub 2021 Apr 16.

Gastroliver Foundation, Dhaka, Bangladesh.

Introduction: Functional dyspepsia (FD), although commoner than organic dyspepsia (OD) in-hospital studies, community data, particularly from rural areas, are lacking. We performed a rural community study in Bangladesh with the primary aims to evaluate (i) the prevalence of uninvestigated dyspepsia (UD), FD, and OD and (ii) the risk factors for UD.

Methods: This house-to-house survey was performed using a translated-validated enhanced Asian Rome III questionnaire and endoscopy with Helicobacter pylori tests, including genotyping. Read More

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Parents' attitudes towards school students' overuse of smartphones and its detrimental health impacts: A qualitative study.

JMIR Pediatr Parent 2021 Apr 20. Epub 2021 Apr 20.

Department of Immunology, Ministry of Health-Kuwait, Kuwait, KW.

Background: Parents' awareness of the risks of the overuse of smartphones (SPs) among their children and parents' attitudes towards this societal phenomenon are crucial factors to consider when investigating the causes and effects of, as well as interventions to control, this public health issue.

Objective: This study aimed to explore the awareness and attitudes of parents regarding SP overuse among their children and the detrimental impacts associated with it.

Methods: The qualitative method of semi-structured face-to-face interviews was used to collect data from fathers and mothers of children aged 6-18 years. Read More

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Learning from the Experiences of COVID-19 Survivors: A Descriptive Study.

JMIR Form Res 2021 Apr 13. Epub 2021 Apr 13.

Dartmouth College, 9 Maynard Street, Hanover, US.

Background: There are still many unanswered questions about the novel coronavirus, however, a largely underutilized source of knowledge are the millions of people who have recovered after contracting the virus. This includes majority of undocumented cases of the COVID-19 which are classified as mild or moderate and received little to no clinical care during the course of illness.

Objective: To document and glean insights from the experiences of persons with first-hand experience with coronavirus, especially the so-called mild to moderate cases that self-resolved in isolation. Read More

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A Strategy for Integrative Reconstruction of Midface Defects Using an Extended Forehead Flap.

Facial Plast Surg Aesthet Med 2021 Apr 20. Epub 2021 Apr 20.

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.

Midface reconstruction is challenging because the structures and deformities involved are complicated. In this study, we present a strategy for integrally reconstructing nasal and midface defects, including hair-bearing defects, using extended forehead-expanded flaps. From 2015 to 2018, a total of 22 patients with midface defects underwent reconstruction with extended forehead-expanded flaps. Read More

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Prevalence of the presystolic wave in echocardiography and its association with the extent of coronary artery disease in patients with chronic stable angina.

Echocardiography 2021 Apr 20. Epub 2021 Apr 20.

Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: Since mortality and morbidity of coronary artery disease are high, there is a need for non-invasive diagnostic methods for early diagnosis and prediction of ischemic heart disease (IHD) outcome. This study aimed to assess the relationship between angiographic findings, the Presystolic wave (PSW) and some of the ischemic related parameters in echocardiography of the patients with chronic stable angina.

Materials And Methods: This cross-sectional study was conducted on the patients with chronic angina pectoris who referred to a tertiary hospital for coronary angiography in Mashhad, Iran. Read More

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Health-related quality of life in children at the diagnosis of Vernal Keratoconjunctivitis.

Pediatr Allergy Immunol 2021 Apr 20. Epub 2021 Apr 20.

Translational Specialized Pediatrics Research Area, Allergic Diseases Research Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

Background: Vernal keratoconjunctivitis (VKC) is a bilateral, chronic, allergic condition mostly affecting children. Clinical evaluations may not necessarily reflect the impact of the disease on the patients' health-related quality of life (HRQoL). We aimed to evaluate HRQoL in children at VKC diagnosis and to analyze correlations between HRQoL and clinical and laboratory variables. Read More

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Trends in Coronavirus Disease 2019 Hospitalization and Prognosis: Gender Effect.

Curr Med Sci 2021 Apr 20;41(2):312-317. Epub 2021 Apr 20.

Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

We here aimed to investigate the impact of gender on the clinical characteristics and laboratory results of patients with coronavirus disease 2019 (COVID-19) and provide clues to the pathological mechanisms underlying COVID-19. A retrospective study was performed. Clinical characteristics, severity of lung infection, laboratory results, and prognoses of patients of different gender were analyzed. Read More

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Concurrent positive skin tests to prophylactic antibiotics and rocuronium in two patients with life-threatening anaphylaxis after induction of anesthesia.

JA Clin Rep 2021 Apr 20;7(1):37. Epub 2021 Apr 20.

Department of Anesthesiology and Critical Care, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3 Minami-ku, Hiroshima, 734-8551, Japan.

Background: Prophylactic antibiotics and neuromuscular blocking agents (NMBA) are two of the major causative agents of anaphylaxis after induction of anesthesia.

Case Presentation: One female and one male patients (aged 29 and 69 years, respectively) had Ring and Messmer scale grade III anaphylaxis after administration of prophylactic antibiotics following induction of anesthesia. They showed typical hemodynamic and respiratory features of life-threatening anaphylaxis. Read More

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Correlation between intraocular pressure obtained with water drinking test versus modified diurnal tension curve measurement in pseudoexfoliation glaucoma.

Int Ophthalmol 2021 Apr 20. Epub 2021 Apr 20.

Department of Ophthalmology, Malatya State Hospital, Malatya, Turkey.

Purpose: The aim of this paper was to study the correlation and agreement between the intraocular pressure (IOP) peak value and fluctuations detected with the modified diurnal tension curve (mDTC) and the water drinking test (WDT) in pseudoexfoliation glaucoma (XFG) patients.

Methods: This prospective observational study enrolled 42 eyes of 42 XFG patients. The IOPs were measured at 2-h intervals from 8 am to 4 pm with a Goldmann applanation tonometer by a single observer to establish the mDTC. Read More

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Unicompartmental knee arthroplasty: all-poly versus metal-backed tibial component-a long-term follow-up study.

Int Orthop 2021 Apr 20. Epub 2021 Apr 20.

S. Giovanni Calibita Fatebenefratelli Hospital, Isola Tiberina, 00186, Rome, Italy.

Introduction: While considered a satisfactory solution, unicompartmental knee arthroplasty (UKA) still raises concerns in regard to its durability. These concerns particularly focus on the tibial component. This study aims to compare two different cemented tibial components belonging to the same UKA design: all polyethylene (AP) versus metal backed (MB), at a long-term follow-up. Read More

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Quantitative Genetic Mapping and Genome Assembly in the Lesser Wax Moth Achroia grisella.

G3 (Bethesda) 2019 Jul;9(7):2349-2361

Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045.

Specific characteristics of the male Achroia grisella acoustic mating signal determine a male's attractiveness toward females. These features are genetically variable in populations, and mapping experiments have been used to identify loci contributing to song variation, and understand the evolutionary forces acting on this important sexual trait. Here we built on this foundation and carried out QTL (Quantitative Trait Locus) mapping using >1,000 recombinant individuals, genotyping this large cohort at thousands of sequence-based markers covering the entire collection of 30 A. Read More

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Learning the Mental Health Impact of COVID-19 in the United States With Explainable Artificial Intelligence: Observational Study.

JMIR Ment Health 2021 Apr 20;8(4):e25097. Epub 2021 Apr 20.

Indraprastha Institute of Information Technology, New Delhi, India.

Background: The COVID-19 pandemic has affected the health, economic, and social fabric of many nations worldwide. Identification of individual-level susceptibility factors may help people in identifying and managing their emotional, psychological, and social well-being.

Objective: This study is focused on learning a ranked list of factors that could indicate a predisposition to a mental disorder during the COVID-19 pandemic. Read More

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Prevalence and determinants of quitting smoking after cancer diagnosis: a prospective cohort study.

Tumori 2021 Apr 20:3008916211009301. Epub 2021 Apr 20.

Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.

Objective: To describe smoking behaviours of patients with incident cancer attending an Italian cancer centre and to examine changes in their smoking habits within 12 months from cancer diagnosis, evaluating determinants of smoking cessation.

Methods: A hospital-based prospective cohort included patients hospitalized in an Italian cancer centre (2016-2018). Patients were mostly female (74%) and included a limited proportion of aerodigestive cancers (7%). Read More

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Coronavirus disease 2019 (COVID-19) among hospitalized patients in Poland: a study based on a national hospital registry.

Pol Arch Intern Med 2021 Apr 20. Epub 2021 Apr 20.

Introduction: Coronavirus disease 2019 (COVID-19) has been identified by the World Health Organization as a global pandemic. Poland introduced extensive anti-epidemic measures relatively early, in order to slow down the spread of the disease.

Objectives: The study aims at presenting recent data on COVID-19 hospitalization cases during the first months of this outbreak in Poland. Read More

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Sex modifies APOE ε4 dose effect on brain tau deposition in cognitively impaired individuals.

Brain 2021 Apr 20. Epub 2021 Apr 20.

Mallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.

Recent studies in cognitively unimpaired elderly individuals suggest that the APOE ε4 allele exerts a dosage-dependent effect on brain tau deposition. The aim of this study was to investigate sex differences in APOE ε4 gene dosage effects on brain tau deposition in cognitively impaired individuals using quantitative 18F-flortaucipir PET. Preprocessed 18F-flortaucipir tau PET images, T1-weighted structural MRI images, demographic information, global cortical amyloid-β burden measured by 18F-florbetapir PET, CSF total tau and phosphorylated tau measurements were obtained from the Alzheimer's Disease Neuroimaging Initiative database. Read More

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Long-term neurodevelopmental outcome after prenatal exposure to maternal hematological malignancies with or without cytotoxic treatment.

Child Neuropsychol 2021 Apr 20:1-12. Epub 2021 Apr 20.

Center for Gynecologic Oncology Amsterdam, the Netherlands Cancer Institute, Amsterdam, The Netherlands.

Data on the long-term neurodevelopmental outcomes of children exposed to hematological maternal cancer with or without treatment during pregnancy are lacking. A total of 57 children, of whom 33 males and 24 females, prenatally exposed to hematological malignancies and its treatment, were invited for neuropsychological and physical examinations at 18 months, 36 months, 6, 9, 12, 15 and 18 years of age. Oncological, obstetrical, neonatal and follow-up data of these children were collected. Read More

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First Report of Meloidogyne graminicola on Rice in Henan Province, China.

Plant Dis 2021 Apr 20. Epub 2021 Apr 20.

Institute of Plant Protection, Chinese Academy of Agricultural Sciences, West Yuanmingyuan Road No.2,, Beijing, China, 100193;

Rice (Oryza sativa) is an important food crop in China and root-knot nematode Meloidogyne graminicola has been one of the most important diseases on rice in recently five years (Ju et al. 2020). In August 2020, rice plants were found to be maldeveloped, yellow leaves and hooked root tips in an irrigated paddy field of Yuanyang County, Xinxiang City, Henan Province. Read More

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CT findings of COVID-19 pneumonia in ICU-patients.

J Public Health Res 2021 Apr 19. Epub 2021 Apr 19.

Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.) di Cagliari, Polo di Monserrato (CA).

Background: In December 2019, a cluster of unknown etiology pneumonia cases occurred in Wuhan, China leading to identification of the responsible pathogen as SARS-coV-2. Since then, the coronavirus disease 2019 (COVID-19) has spread to the entire world. Computed Tomography (CT) is frequently used to assess severity and complications of COVID-19 pneumonia. Read More

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