410,693 results match your criteria male presented

A rare case of a laryngeal leiomyosarcoma with a lymph node metastasis.

Int J Surg Case Rep 2021 Mar 23;82:105830. Epub 2021 Mar 23.

ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Casablanca, Morocco. Electronic address:

Introduction: Leiomyosarcoma is a rare mesenchymal tumor that originates from smooth muscle cells. Head and neck LMSs represent only 3% of all leiomyosarcomas with less than 50 cases of laryngeal LMS reported in the literature till now.

Case Presentation: We report a case of 50-year-old male presented at our ENT department for a chronic hoarseness. Read More

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AFB-induced mice liver injury involves mitochondrial dysfunction mediated by mitochondrial biogenesis inhibition.

Ecotoxicol Environ Saf 2021 Apr 7;216:112213. Epub 2021 Apr 7.

Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.

Aflatoxin B1 (AFB) pollutes foodstuffs and feeds, causing a food safety problem and seriously endangering human and animal health. Liver is the principal organ for AFB accumulation and biotransformation, during which AFB can cause acute and chronic liver damage, however, the specific mechanism is not completely clear. Mitochondria are the primary organelle of cellular bio-oxidation, providing 95% energy for liver to execute its multiple functions. Read More

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Automated blood sampling in canine telemetry studies: Enabling enhanced assessments of cardiovascular liabilities and safety margins.

J Pharmacol Toxicol Methods 2021 Apr 7:107066. Epub 2021 Apr 7.

AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.

Introduction: A successful integration of automated blood sampling (ABS) into the telemetry instrumented canine cardiovascular model is presented in this study. This combined model provides an efficient means to quickly gain understanding of potential effects on key cardiovascular parameters in dog while providing a complete Pharmacokinetic/Pharmacodynamic (PK/PD) profile for discovery compounds without handling artifacts, reducing the need for a separate pharmacokinetic study.

Methods: Male beagle dogs were chronically implanted with telemetry devices (PhysioTel™ model D70-PCTP) and vascular access ports (SPMID-GRIDAC-5NC). Read More

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Cutaneous involvement by T- cell prolymphocytic leukemia presenting as livedoid vasculopathy.

J Cutan Pathol 2021 Apr 10. Epub 2021 Apr 10.

Department of Pathology, Duke University Medical Center, Durham, NC.

T-cell prolymphocytic leukemia (T-PLL) is a rare, aggressive neoplasm derived from post-thymic T-cells. Patients are typically middle-aged with a slight male predominance who present with a high white blood cell count, hepatosplenomegaly, lymphadenopathy, and other symptoms typically associated with leukemia. Although cutaneous involvement has been reported in up to 30% of cases of T-PLL, to our knowledge, none have presented with a presentation resembling livedoid vasculopathy. Read More

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News Journalists and Postruamatic Stress Disorder: a Review of Literature, 2011-2020.

Psychiatr Q 2021 Apr 10. Epub 2021 Apr 10.

Harvard Medical School, Boston, MA, USA.

Research has demonstrated that first responders may develop psychological trauma/ posttraumatic stress disorder (PTSD) in the performance of their duties. Often overlooked in these studies of police, firefighters, and paramedics is an additional group of providers who also respond to these same events: news journalists and photo journalists. Although limited in scope, the research literature from 1980 to 2010 assessed an association between PTSD and some news journalists. Read More

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Epidural abscess related to in a 57-year-old immunocompetent patient.

BMJ Case Rep 2021 Apr 9;14(4). Epub 2021 Apr 9.

Neuro Orthopedic Center, La Source College of Health, Lausanne, Vaud, Switzerland.

A 57-year-old immunocompetent male patient presented himself to our emergency department with lumbar pain for 10 days, after a lumbar torsion. He was neurologically intact, but showed signs of systemic inflammatory syndrome. A lumbar MRI found a spinal epidural abscess from L3-L4 to L5-S1 levels. Read More

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Undifferentiated colonic neoplasm with SMARCA4 germline gene mutation and loss of SMARCA4 protein expression: a case report and literature review.

Diagn Pathol 2021 Apr 9;16(1):30. Epub 2021 Apr 9.

Department of Pathology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, China.

Background: Nonsense mutation or inactivation of SMARCA4 (BRG1) is associated with a monomorphic undifferentiated histological appearance in tumors at different sites. The association between SMARCA4 alteration and undifferentiated colonic carcinoma needs to be further elucidated.

Methods: A 61-year-old male patient presented to the hospital with intermittent epigastric pain in the right upper abdomen and abdominal distension. Read More

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Abdominal Aorta Bullet Embolism: Presentation and Management.

Ann Vasc Surg 2021 Apr 6. Epub 2021 Apr 6.

Department of Surgery, Broward Health Medical Center, Fort Lauderdale, FL, 33316.

Penetrating cardiac injury (PCI) secondary to a gunshot wound presents with several complications and a mortality rate of 94% before reaching the hospital. Current literature search reveals that embolism of bullet fragments after gunshot wounds are exceptionally rare. Additionally, no reported case was found regarding bullet embolism following left atrium penetration at the time of this case report. Read More

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A case of Infective Native (Abdominal) Aortic Aneurysm caused by Streptococcus Agalactiae: An updated literature review based on new nomenclature.

Ann Vasc Surg 2021 Apr 6. Epub 2021 Apr 6.

Department of Vascular Surgery, King's College Hospital, Denmark Hill, SE5 9RS, London, United Kingdom. Electronic address:

The management of abdominal aortic aneurysms (AAA) has evolved significantly with the advent of endovascular strategies. Thus, there has been a decline in the number of open AAA repairs once an endovascular option is available. There have also been reports of successful endovascular management of infective native aortic aneurysms (INAA) [1], previously called mycotic aneurysms [2]. Read More

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False-Positive Nonstructural Protein 1 Antigen in a Patient with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Case Report with Literature Review.

Am J Case Rep 2021 Apr 9;22:e928865. Epub 2021 Apr 9.

Division of Hematology, Department of Medicine, Rajavithi Hospital, Bangkok, Thailand.

BACKGROUND A rapid investigation of dengue viral infection is needed for physicians who manage patients with suspected dengue infection. The nonstructural protein 1 (NS1) test kit is commonly used to diagnose patients with acute febrile illness in dengue-endemic countries, although this test kit can yield false-positive results. The Dengue NS1 test kit mostly relies on cross-reaction among febrile illness patients with other viral infections rather than malignancies. Read More

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A Descriptive Study Exploring Semen Quality Among Indian Cancer Patients.

J Adolesc Young Adult Oncol 2021 Apr 9. Epub 2021 Apr 9.

Department of Reproductive Medicine, Gunasheela Surgical and Maternity Hospital, Bangalore, India.

To descriptively explore semen quality among Indian men with various types of malignancies. We evaluated semen parameters of male patients referred to our hospital before commencing their cancer treatment. Four hundred sixty-one male patients who were within the age range of 15-50 years were recruited with diagnosed malignancies. Read More

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Two Atypical Cases of Tick Bites: A Fully Engorged Tick and Multiple Ticks.

Tokai J Exp Clin Med 2021 Apr 20;46(1):26-28. Epub 2021 Apr 20.

Department of Dermatology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

Ticks have a cosmopolitan distribution and, as such, are also found in Japan. Ticks are typically ectoparasites of wild animals, however, humans can also be bitten when visiting environments inhabited by ticks. Herein, we describe two cases with atypical tick bites. Read More

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Characteristic localization patterns of thrombus on various brands of bileaflet mitral mechanical heart valves as assessed by three-dimensional transesophageal echocardiography and their relationship with thromboembolism.

Int J Cardiovasc Imaging 2021 Apr 9. Epub 2021 Apr 9.

Department of Cardiology, Kosuyolu Kartal Heart Training and Research Hospital, Denizer caddesi, Cevizli Kavsagi, Kartal, 34865, Istanbul, Turkey.

Three-dimensional transesophageal echocardiography (3D-TEE) provides detailed images of prosthetic valve thrombosis (PVT). However, data regarding PVT localization patterns based on 3D-TEE and their association with clinical findings among various bileaflet mitral prosthetic valve brands is lacking. The locations of thrombi were classified into 4 groups according to hinge and annulus involvement based on 3D-TEE: ring-like PVT involving entire mitral annulus (type-1), PVT involving peri-hinge(s) region and extends through some part of the annulus (type-2), PVT involving mitral annulus without involving hinge(s) region (type-3), and PVT involving only (peri)hinge(s) area (type-4). Read More

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Neuropsychiatric manifestations in an adolescent male with Rowell syndrome.

J Postgrad Med 2021 Apr 8. Epub 2021 Apr 8.

Department of Pathology, Yenepoya Medical College, Yenepoya (Deemed to be University), Mangalore, Karnataka, India.

A 15-year-old boy presented with fever, skin, and oral lesions for 4 weeks. The cutaneous lesions were suggestive of subacute cutaneous lupus erythematosus and erythema multiforme. His clinical, histopathological, and immunological features were indicative of Rowell syndrome and he satisfied the diagnostic criteria of Rowell syndrome proposed by Zeitouni et al. Read More

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Feel the Burn! Fireworks-related Otolaryngologic Trauma.

Ann Otol Rhinol Laryngol 2021 Apr 9:34894211008100. Epub 2021 Apr 9.

Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA.

Objectives: Fireworks are used commonly for celebrations in the United States, but can lead to severe injury to the head and neck. We aim to assess the incidence, types, and mechanisms of head and neck injuries associated with fireworks use from 2010 to 2019.

Methods: A retrospective cross-sectional study, using data from the National Electronic Injury Surveillance System, of individuals presenting to United States Emergency Departments with head and neck injuries caused by fireworks and flares from 2010 to 2019. Read More

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Periprocedural and In-Hospital Outcomes Among Percutaneous Coronary Intervention in Saphenous Vein Graft: A Retrospective Observational Study at a Tertiary Care Hospital in South Asian Country.

Cureus 2021 Apr 1;13(4):e14251. Epub 2021 Apr 1.

Cardiology, Aga Khan University Hospital, Karachi, PAK.

Background Saphenous vein graft (SVG) may occlude either early or several months to years after coronary artery bypass graft (CABG) surgery. Doing re-do CABG surgery is associated with higher complication and mortality rate as compared to percutaneous coronary intervention (PCI) in SVG. However, PCI of SVG is associated with more periprocedural and in-hospital complications as compared to PCI of native coronary arteries. Read More

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Images in Spine: A Rare Abnormal Bony Fusion.

Cureus 2021 Mar 5;13(3):e13719. Epub 2021 Mar 5.

Neurological Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, USA.

Klippel-Feil syndrome (KFS) is characterized by failed segmentation of the cervical spine leading to inappropriately fused vertebral bodies. A 64-year-old male with a previous L5-S1 decompression presented with significant neck pain with radiation into the entire right upper extremity and hand. Imaging demonstrated fusion of the vertebral bodies at C2-3, C4-6, and C7-T1 with associated disc bulges at C3-4 and C6-7. Read More

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Cerebral Venous Sinus Thrombosis in an Immunocompetent HIV Patient.

Cureus 2021 Mar 4;13(3):e13694. Epub 2021 Mar 4.

Neurology, Creighton University School of Medicine, Omaha, USA.

Cerebral venous sinus thrombosis (CVST) is an uncommon manifestation in patients with the human immunodeficiency virus (HIV) due to the virus's prothrombotic state. Our case involves a 41-year-old Hispanic male with a past medical history of HIV on bictegravir/emtricitabine/tenofovir/alafenamide (Biktarvy), hyperlipidemia, post-traumatic stress disorder, hypogonadism with the cessation of testosterone injections one month prior, and generalized anxiety disorder who presented with retro-orbital headache, intermittent bilateral blurry vision, and flashing lights in the lower lateral left eye for one week. Vitals signs and laboratory studies were within normal limits aside from new iron deficiency anemia. Read More

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How Does a Sport Psychological Intervention Help Professional Cyclists to Cope With Their Mental Health During the COVID-19 Lockdown?

Front Psychol 2021 23;12:607152. Epub 2021 Mar 23.

Behavioral Imaging and Neural Dynamics (BIND) Center, Department of Medicine and Aging Sciences, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.

All around the world in March, due to COVID-19, competitive sport calendars were suddenly canceled, jeopardizing the training programs of athletes. Moreover, in Italy, the government banned all non-essential travel across the entire country from the beginning of March. Consequently, Italian cyclists were banned from leaving their homes and therefore unable to perform their ordinary training activities. Read More

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The role of chest CT quantitative pulmonary inflammatory index in the evaluation of the course and treatment outcome of COVID-19 pneumonia.

Sci Rep 2021 04 8;11(1):7752. Epub 2021 Apr 8.

Department of Radiology, First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Chongqing, 400016, China.

To explore the clinical application value of chest CT quantitative pulmonary inflammation index (PII) in the evaluation of the course and treatment outcome of COVID-19 pneumonia. One hundred and eighteen patients with COVID-19 pneumonia diagnosed by RT-PCR were analyzed retrospectively. The correlation between chest CT PII, clinical symptoms and laboratory examinations during the entire hospitalization period was compared. Read More

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Epidemiology, treatment patterns and healthcare utilizations in multiple sclerosis in Taiwan.

Sci Rep 2021 Apr 8;11(1):7727. Epub 2021 Apr 8.

Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Room 220, 33, Linsen S. Rd, Taipei, 10050, Taiwan.

"Real-world" data on the nationwide epidemiology and treatment patterns of multiple sclerosis (MS) is very scarce in Asia. This study is aim to evaluate the 10-years trends in epidemiology and treatment patterns of MS with Taiwan's National Health Insurance Database (NHIRD). Patients aged 20 years or older and were newly diagnosed with MS between 2007 and 2016 were identified. Read More

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Corrective osteotomy for malunion of distal diaphyseal/metaphyseal radius or ulna fracture affecting stability of the distal radioulnar joint.

Injury 2021 Apr 1. Epub 2021 Apr 1.

Department of Orthopedic Surgery, Regional Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.

Background: We postulated that residual distal radioulnar joint (DRUJ) instability after distal diaphyseal or metaphyseal fracture in the radius or ulna may occur due to malaligned or malunited bony structures as well as primary or secondary soft issue stabiliser. Here, we report the outcomes of corrective osteotomy in a retrospective study.

Methods: Patients undergoing the osteotomy for DRUJ instability between March 2000 and February 2018 were included in the study. Read More

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Gastrointestinal symptoms as first remarkable signs of ANCA-associated granulomatosis with polyangiitis: a case report and reviews.

BMC Gastroenterol 2021 Apr 8;21(1):158. Epub 2021 Apr 8.

Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Background: Systemic vasculitis associated with antineutrophil cytoplasmic autoantibodies (ANCA) have an extremely wide variety of symptoms, therefore the fast and proper diagnosis is difficult to establish even for experienced physicians. Gastrointestinal manifestations in ANCA-associated granulomatosis with polyangiitis (GPA) may be present, however, severe, life-threatening complications (such as perforations) are rare.

Case Presentation: A case of an 18-year-old male patient is presented, where gastrointestinal symptoms (abdominal pain, vomiting, diarrhoea) were the first remarkable signs of GPA. Read More

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The application of chimeric deep circumflex iliac artery perforator flap for oromandibular reconstruction: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25458

Department of Head and Neck Cancer Center.

Rationale: The free fibular flap is considered the gold standard, particularly for a mandibular defect combined with a significant soft tissue defect. However, the fibular flap has the disadvantages of a lack of height for postoperative dental restoration and donor site skin graft if the skin paddle is wider than 5 cm. The larger bone and soft tissue defects tend to be reconstructed using either a scapula or a combination of iliac artery and radial free flap. Read More

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Severe hypercalcemia in a patient with chronic lymphocytic leukemia and non-small cell lung carcinoma: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e24982

Endocrinology Unit, HaEmek Medical Center.

Rationale: Hypercalcemia is a common finding in patients with advanced-stage cancers. Paraneoplastic hypercalcemia is commonly associated with dismal prognoses, with survival rates of about 3 months. In this paper, we report on a patient with advanced chronic lymphocytic leukemia and non-small cell lung carcinoma who developed severe hypercalcemia and discuss the diagnosis and treatment of this metabolic complication. Read More

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Management of Mycotic Thoracic Aortic Aneurysm with Staged Hybrid Approach.

Ann Vasc Surg 2021 Apr 5. Epub 2021 Apr 5.

Medical College of Georgia at Augusta University, Department of Surgery, Division of Vascular and Endovascular Surgery, Augusta, Georgia.

We report a case of mycotic thoracic aortic aneurysm managed by staged hybrid repair. A 30-year-old male patient with polysubstance abuse presented with chest pain and elevated white blood cell count. CTA performed showed a rapidly developing mycotic thoracic aortic pseudoaneurysm. Read More

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Environmental and clinical isolates of induce pulmonary infection in mice and its secretome is cytotoxic to human lung cells.

J Med Microbiol 2021 Apr;70(4)

Department of Structural Biology, Molecular and Genetics, State University of Ponta Grossa, Paraná State, Brazil.

In recent years, the genus has emerged as a pathogen in healthcare-related infections and has became stablished as an opportunistic pathogen. Little is known about the pathogenesis induced by genus. To evaluate the cytotoxic effects of genus , its ability to adhere to lung human cells and the ability of environmental and clinical strains of to induce pneumonia in mice. Read More

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Spontaneous hemopneumothorax in an adolescent with COVID-19.

J Pediatr Surg Case Rep 2021 Jun 2;69:101852. Epub 2021 Apr 2.

Department of Pediatrics and Surgery, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT, 06030, USA.

As coronavirus disease 2019 (Covid-19) continues to spread world-wide, new symptoms associated with the disease continue to appear. Common manifestations include fever, shortness of breath, and gastrointestinal illness. In addition, COVID is known to induce coagulopathy. Read More

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Left Ventricular Thrombus: An Interesting Presentation of Primary Antiphospholipid Antibody Syndrome with a Mini-review of the Literature.

J Cardiovasc Echogr 2020 Oct-Dec;30(4):217-222. Epub 2021 Jan 20.

Department of Cardiology, Government General Hospital, Kurnool, Andhra Pradesh, India.

Antiphospholipid syndrome (APLS) is characterized by recurrent thrombosis. We report the case of a 36-year-old male who had acute right-sided ischemic stroke and right leg ischemia secondary to left ventricular (LV) thrombus caused by primary APLS. The literature review suggested that the LV thrombus presented most commonly with systemic embolism and was associated with a mortality rate of 22. Read More

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January 2021

Music-Evoked Nostalgia and Wellbeing During the United Kingdom COVID-19 Pandemic: Content, Subjective Effects, and Function.

Front Psychol 2021 22;12:647891. Epub 2021 Mar 22.

York Music Psychology Group, Department of Music, University of York, York, United Kingdom.

Nostalgic music is defined as that which evokes feelings of nostalgia through reminders of certain periods of life, places or people. Feelings of nostalgia are said to occur during times of hardship and difficult transitionary periods, such as the first COVID-19 lockdown in the United Kingdom in 2020. Here, the reassurance of the past might have held certainty that could sustain a sense of meaning and purpose in life and influence wellbeing. Read More

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