34,369 results match your criteria major issues

Extrusion-based 3D printing of ex situ-alloyed highly biodegradable MRI-friendly porous iron-manganese scaffolds.

Acta Biomater 2021 Jul 23. Epub 2021 Jul 23.

Department of Biomechanical Engineering, Faculty of Mechanical, Maritime, and Materials Engineering, Delft University of Technology, Mekelweg 2, 2628 CD Delft, The Netherlands.

Additively manufactured biodegradable porous iron has been only very recently demonstrated. Two major limitations of such a biomaterial are very low biodegradability and incompatibility with magnetic resonance imaging (MRI). Here, we present a novel biomaterial that resolves both of those limitations. Read More

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Nursing Difficulties and Issues in Endoscopic Sedation: Qualitative Research in Japan.

Gastroenterol Nurs 2021 Jul 20. Epub 2021 Jul 20.

Miki Matsubayashi, MSN, is Clinical Nurse, Social Medical Corporation Sousei Hospital, Kadoma City, Osaka, Japan. Keiko Nakamura, DNP, is Specially Appointed Professor, Acute Illness, Adult Nursing, Graduate School of Nursing, Sapporo City University, Sapporo, Hokkaido, Japan. Miki Sugawara, DNP, is Associate Professor, Acute Illness, Adult Nursing, Graduate School of Nursing, Sapporo City University, Sapporo, Hokkaido, Japan. Shigeko Kamishima, DNP, is Associate Professor, Acute Illness, Adult Nursing, Graduate School of Nursing, Sapporo City University, Sapporo, Hokkaido, Japan.

Gastrointestinal endoscopic treatments have increased in Japan. Respiratory depression is as an unexpected development during sedation. This study aimed to clarify the sedation-related difficulties encountered by nurses involved in endoscopic treatment. Read More

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Digital risks and adolescents: The relationships between digital game addiction, emotional eating, and aggression.

Int J Ment Health Nurs 2021 Jul 26. Epub 2021 Jul 26.

Child Health and Diseases Nursing Department, Akdeniz University Kumluca Health Sciences Faculty, Antalya, Turkey.

Nowadays, weight gain and obesity are major health-threatening issues for children. Emotional eating, a negative health condition that can lead to obesity in children, is a defence mechanism for coping with negative emotions. This cross-sectional study aimed to evaluate the relationships between emotional eating behaviour and digital game addiction, which can cause stress and aggression in adolescents. Read More

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Food safety, food security and genetically modified organisms in Africa: a current perspective.

Biotechnol Genet Eng Rev 2021 Jul 26:1-34. Epub 2021 Jul 26.

Department of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, P.O Box 17011, Doornfontein Campus, 2028, Gauteng, South Africa.

Moving forward from 2020, Africa faces an eminent challenge of food safety and security in the coming years. The World Food Programme (WFP) of the United Nations (UN) estimates that 20% of Africa's population of 1.2 billion people face the highest level of undernourishment in the world, likely to worsen due to COVID-19 pandemic that has brought the entire world to its knees. Read More

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Mental Health and COVID-19: Policies, Guidelines, and Initiatives from the Asia-Pacific Region.

Asia Pac J Public Health 2021 Jul 26:10105395211025901. Epub 2021 Jul 26.

Asia-Europe Institute, University of Malaya, Kuala Lumpur, Malaysia.

The COVID-19 outbreak was declared a pandemic by the World Health Organization in March 2020 due to rapid intercontinental spread and high morbidity and mortality. Globally, the disease has had a major impact on human lives, including health, economic, employment, psychological, and overall well-being. The COVID-19, besides causing respiratory, neurological, and cardiovascular diseases, has had significant impact on mental health. Read More

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Violence Against Women in Tanzania and its Association With Health-Care Utilisation and Out-of-Pocket Payments: An Analysis of the 2015 Tanzania Demographic and Health Survey.

Seema Vyas

East Afr Health Res J 2019 29;3(2):125-133. Epub 2019 Nov 29.

Department of Population Health, London School of Hygiene and Tropical Medicine, London, UK.

Background: Violence against women is a major public health concern. In addition to adverse physical, mental, and sexual and reproductive health consequences, violence against women confers a considerable cost to health services and the health sector as well as to individuals and households in the form of out-of-pocket expenditures. This study aimed to assess whether physical or sexual violence against women is associated with higher health-care utilisation rates and out-of-pocket expenditures in Tanzania. Read More

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November 2019

"Should We Take Them or Leave Them?" A Qualitative Study to Understand the Social, Cultural, and Ethical Issues Associated With the Lifecycle Management of Insecticide-Treated Nets in Tanzania.

East Afr Health Res J 2018 23;2(2):135-141. Epub 2018 Nov 23.

Amani Research Centre, National Institute for Medical Research, Tanga, Tanzania.

Background: Insecticide-treated nets (ITNs) are highly effective in reducing morbidity and mortality from malaria. However, it is widely accepted that ITNs - if not re-treated - lose their effectiveness with time and eventually need to be replaced. This study sought to determine the social, ethical, and cultural issues related to the lifecycle of ITNs, which includes net ownership, usage, maintenance, reuse, recycling, disposal, and replacement. Read More

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November 2018

Clinical trials proposed for the VA Cooperative Studies Program: Success rates and factors impacting approval.

Contemp Clin Trials Commun 2021 Sep 9;23:100811. Epub 2021 Jul 9.

Cooperative Studies Program, Office of Research and Development, Veterans Health Administration, Washington DC, 20420, USA.

The process by which funding organizations select among the myriad number of proposals they receive is a matter of significant concern for researchers and the public alike. Despite an extensive literature on the topic of peer review and publications on criteria by which clinical investigations are reviewed, publications analyzing peer review and other processes leading to government funding decisions on large multi-site clinical trials proposals are sparse. To partially address this gap, we reviewed the outcomes of scientific and programmatic evaluation for all letters of intent (LOIs) received by the Department of Veterans Affairs (VA) Cooperative Studies Program (CSP) between July 4, 2008, and November 28, 2016. Read More

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September 2021

Investigating correlations between illness and defensive behaviour approach: A case of twin cities of Pakistan.

Heliyon 2021 Jun 16;7(6):e07327. Epub 2021 Jun 16.

School of Social Sciences and Humanities, National University of Sciences and Technology (NUST), Islamabad, Pakistan.

Municipal solid waste (MSW) management has emerged as a major problem for modern societies in recent decades. An optimal waste management system is essential to prevent the pollution burden and associated health related issues. This study carries out an empirical evaluation of the illness caused by inadequate solid waste management in the metropolitan of Rawalpindi-Islamabad. Read More

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Fatalism and exposure to health information from the media: examining the evidence for causal influence.

Ann Int Commun Assoc 2017 19;41(3-4):298-320. Epub 2017 Oct 19.

Public Health, University of California, Merced, CA, USA.

Fatalistic attitudes have a negative impact on a broad variety of health behaviors and behavioral determinants of health. A growing body of research has documented an association between media exposure and fatalism; however, scholarship has not been able to ascertain the causal direction. This review synthesizes the current state of the literature. Read More

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October 2017


Int J Adv Res (Indore) 2020 May;8(5):1245-1254

College of Public Health, The University of Iowa, United States.

The purpose of the current study was to identify the existing practices and policies on TBI treatment and rehabilitation in the Republic of Moldova.

Methods: Qualitative face-to-face interviews were conducted with health care professionals from two major emergency hospitals in Chisinau Municipality in 2018. An interview guide was modeled according to a standard operation procedure with a set of concrete questions. Read More

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Standardizing and optimizing acupuncture treatment for irritable bowel syndrome: A Delphi expert consensus study.

Integr Med Res 2021 Sep 24;10(3):100728. Epub 2021 Apr 24.

International Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China.

Background: Acupuncture has been widely utilized for irritable bowel syndrome (IBS). However, heterogeneity is large among therapeutic strategies and protocols. The aim of this study was to propose some down-to-earth recommendations and establish an optimized protocol for acupuncture practice in IBS. Read More

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September 2021

Reductions in Muscle Strength and Range of Motion Cause Locomotion Disability via Locomotion-Related Functional Limitation in Japanese Older Adults: A Cross-Sectional Study.

J Aging Res 2021 7;2021:6627767. Epub 2021 Jul 7.

Graduate School of Integrated Arts and Sciences, Hiroshima University, 1-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8521, Japan.

Background: Functional issues (impairments, functional limitations, and disabilities) gradually occur with age. Nonetheless, maintaining physical capability may help prevent locomotion disabilities at an older age. The present study aimed to determine whether reductions in muscle strength and range of motion (ROM) cause locomotion disability via locomotion-related functional limitations among healthy older adults. Read More

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Malaria and Helminth Coinfection among Children at the Douala Gyneco-Obstetric and Pediatric Hospital.

J Trop Med 2021 1;2021:3702693. Epub 2021 Jul 1.

Department of Animal Biology, Faculty of Science, University of Dschang, P. O. Box 067, Dschang, Cameroon.

Background: Malaria and helminth infections are major public health issues in sub-Saharan Africa including Cameroon. This study was aimed at determining the prevalence and risk factors associated with malaria and helminth coinfection among children in the Douala Gyneco-Obstetric and Pediatric Hospital (HGOPED) in Douala, southwestern Cameroon. . Read More

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Multi-Pharmacology of Berberine in Atherosclerosis and Metabolic Diseases: Potential Contribution of Gut Microbiota.

Front Pharmacol 2021 9;12:709629. Epub 2021 Jul 9.

Guang'an men Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Atherosclerosis (AS), especially atherosclerotic cardiovascular diseases (ASCVDs), and metabolic diseases (such as diabetes, obesity, dyslipidemia, and nonalcoholic fatty liver disease) are major public health issues worldwide that seriously threaten human health. Exploring effective natural product-based drugs is a promising strategy for the treatment of AS and metabolic diseases. Berberine (BBR), an important isoquinoline alkaloid found in various medicinal plants, has been shown to have multiple pharmacological effects and therapeutic applications. Read More

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Problems in Malaysian children with large angle infantile esotropia: Children and parents' perspectives.

Med J Malaysia 2021 Jul;76(4):526-533

Universiti Sains Malaysia, School of Medical Sciences, Department of Ophthalmology and Visual Science, Kubang Kerian, Kelantan, Malaysia.

Introduction: There is limited information regarding the problems faced by children with large angle infantile esotropia (LAIE). The aim of this study was to explore the problems that children with LAIE encounter from both their perspectives and those of their parents.

Methods: This study included children who had LAIE (with angle of 40 prism dioptres or greater), aged 5 and 17 years who had attended the Ophthalmology Clinic, Hospital Universiti Sains Malaysia from March to September 2016. Read More

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Near Peer Mentors to Address Socio-Emotional Issues Among Underrepresented Minority High School Students in Research Intensive STEM Programs: Perceptions of Students and Mentors.

J STEM Outreach 2020 14;3(1). Epub 2020 May 14.

Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio.

A Near Peer Mentoring Program (NPMP) was developed in which Medical Student Training Program (MSTP) students met weekly with small groups of high school students who were participating in an intensive summer biomedical research immersion program. The goal of the NPMP was to provide and engage the high school students with opportunities to express and discuss their research and more importantly, their stresses and concerns. After initial reservations, the NPMP provided a comfortable venue for high school students to engage in discussions of both laboratory and personal topics. Read More

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Advances in mass spectrometric methods for detection of hemoglobin disorders.

Anal Biochem 2021 Jul 22:114314. Epub 2021 Jul 22.

Department of Biochemistry, University of Delhi South Campus, New Delhi, 110021, India. Electronic address:

Hemoglobin disorders are caused due to alterations in the hemoglobin molecules. These disorders are categorized in two broad classes - hemoglobin variants and thalassemias. The hemoglobin variants arise due to point mutations in the alpha (α), beta (β), gamma (γ), delta (δ), or epsilon (ε) globin chains of these proteins, while thalassemias are caused due to the under-production of α or β globin chain. Read More

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The NEWgenerator non-sewered sanitation system: Long-term field testing at an informal settlement community in eThekwini municipality, South Africa.

J Environ Manage 2021 Jul 21;296:112921. Epub 2021 Jul 21.

Membrane Biotechnology Lab, University of South Florida, Tampa, FL, USA. Electronic address:

Globally, there is a dire need for a new class of advanced non-sewered sanitation systems (NSSS) to provide onsite wastewater treatment that is capable of meeting stringent discharge or reuse criteria. These systems need to be simple to operate and maintain, reliable, and resilient to unreliable electrical service. The NEWgenerator (NG) is a compact, automated, solar-powered wastewater treatment system comprised of three major treatment processes: anaerobic membrane bioreactor (AnMBR), nutrient capture system (NCS) with ion exchange and carbon sorption, and electrochlorination (EC). Read More

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Accuracy assessment of remotely sensed data to analyze lake water balance in semi-arid region.

Sci Total Environ 2021 Jul 14;797:149034. Epub 2021 Jul 14.

Water, Energy and Environmental Engineering Research Unit, PO Box 4300, FI-90014, University of Oulu, Finland.

Lake water level fluctuation is a function of hydro-meteorological components, namely input, and output to the system. The combination of these components from in-situ and remote sensing sources has been used in this study to define multiple scenarios, which are the major explanatory pathways to assess lake water levels. The goal is to analyze each scenario through the application of the water balance equation to simulate lake water levels. Read More

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Phage and phage lysins: New era of bio-preservatives and food safety agents.

Yingmin Xu

J Food Sci 2021 Jul 23. Epub 2021 Jul 23.

Food Technology College Jiangsu Vocational College of Agriculture and Forestry, China.

There has been an increase in the search and application of new antimicrobial agents as alternatives to use of chemical preservatives and antibiotic-like compounds by the food industry. The massive use of antibiotic has created a reservoir of antibiotic-resistant bacteria that find their way from farm to humans. Thus, there exists an imperative need to explore new antibacterial options and bacteriophages perfectly fit into the class of safe and potent antimicrobials. Read More

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A Qualitative Approach to Help Adjust the Design of Management Subjects in ICT Engineering Undergraduate Programs through User Experience in a Smart Classroom Context.

Sensors (Basel) 2021 Jul 12;21(14). Epub 2021 Jul 12.

Faculty of Law, Universidad de Deusto, 48007 Bilbao, Spain.

Qualitative research activities, including first-day of class surveys and user experience interviews on completion of a subject were carried out to obtain students' feedback in order to improve the design of the subject 'Information Systems' as a part of a general initiative to enhance ICT (Information and Communication Technologies) engineering programs. Due to the COVID-19 (corona virus disease 2019) pandemic, La Salle URL adopted an Emergency Remote Teaching tactical solution in the second semester of the 2019-2020 academic year, just before implementing a strategic learning approach based on a new Smart Classroom (SC) system deployed in the campus facilities. The latter solution was developed to ensure that both on-campus and off-campus students could effectively follow the course syllabus through the use of new technological devices introduced in classrooms and laboratories, reducing the inherent difficulties of online learning. Read More

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Real-Time Structural Monitoring of the Multi-Point Hoisting of a Long-Span Converter Station Steel Structure.

Sensors (Basel) 2021 Jul 11;21(14). Epub 2021 Jul 11.

School of Civil Engineering, Sun Yat-sen University, No.135 XinGangXiLu, Guangzhou 510275, China.

In the process of using a long-span converter station steel structure, engineering disasters can easily occur. Structural monitoring is an important method to reduce hoisting risk. In previous engineering cases, the structural monitoring of long-span converter station steel structure hoisting is rare. Read More

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The Relevance and Added Value of Geriatric Medicine (GM): Introducing GM to Non-Geriatricians.

J Clin Med 2021 Jul 7;10(14). Epub 2021 Jul 7.

Working Group on the Development of Geriatric Medicine in Greece of the Hellenic Society for the Study and Research of Aging, 15342 Athens, Greece.

Geriatric Medicine (GM) holds a crucial role in promoting health and managing the complex medical, cognitive, social, and psychological issues of older people. However, basic principles of GM, essential for optimizing the care of older people, are commonly unknown or undermined, especially in countries where GM is still under development. This narrative review aims at providing insights into the role of GM to non-geriatrician readers and summarizing the main aspects of the added value of a geriatric approach across the spectrum of healthcare. Read More

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Optimizing Green-Gray Infrastructure for Non-Point Source Pollution Control under Future Uncertainties.

Int J Environ Res Public Health 2021 Jul 16;18(14). Epub 2021 Jul 16.

School of Water Resources and Environment, China University of Geosciences, Beijing 100083, China.

Non-Point Source Pollution (NPS) caused by polluted and untreated stormwater runoff discharging into water bodies has become a serious threat to the ecological environment. Green infrastructure and gray infrastructure are considered to be the main stormwater management measures, and the issue of their cost-effectiveness is a widespread concern for decision makers. Multi-objective optimization is one of the most reliable and commonly used approaches in solving cost-effectiveness issues. Read More

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A Qualitative Study toward Technologies for Active and Healthy Aging: A Thematic Analysis of Perspectives among Primary, Secondary, and Tertiary End Users.

Int J Environ Res Public Health 2021 Jul 14;18(14). Epub 2021 Jul 14.

IRCCS INRCA-National Institute of Health and Science on Ageing, Innovative Models for Ageing Care and Technology, via S. Margherita 5, 60124 Ancona, Italy.

It is expected that, by 2050, people aged over 60 in 65 nations will constitute 30% of the total population. Healthy aging is at the top of the world political agenda as a possible means for hindering the collapse of care systems. How can ICT/sensing technology meet older people's needs for active and healthy aging? This qualitative study carried out in Italy and Romania in 2020 involved 30 participants: older adults, caregivers, and stakeholders. Read More

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The Long-Term Public Health Impact of Social Distancing on Brain Health: Topical Review.

Int J Environ Res Public Health 2021 Jul 8;18(14). Epub 2021 Jul 8.

Center for Cognitive Neurology, Department of Neurology, New York University Grossman School of Medicine, New York University, New York, NY 10017, USA.

Social distancing has been a critical public health measure for the COVID-19 pandemic, yet a long history of research strongly suggests that loneliness and social isolation play a major role in several cognitive health issues. What is the true severity and extent of risks involved and what are potential approaches to balance these competing risks? This review aimed to summarize the neurological context of social isolation and loneliness in population health and the long-term effects of social distancing as it relates to neurocognitive aging, health, and Alzheimer's disease and related dementias. The full scope of the underlying causal mechanisms of social isolation and loneliness in humans remains unclear partly because its study is not amenable to randomized controlled trials; however, there are many detailed experimental and observational studies that may provide a hypothesis-generating theoretical framework to better understand the pathophysiology and underlying neurobiology. Read More

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Exploring the Social Networks' Use in the Health-Care Industry: A Multi-Level Analysis.

Int J Environ Res Public Health 2021 Jul 8;18(14). Epub 2021 Jul 8.

Department of Movement and Wellness Sciences, Parthenope University of Naples, 80132 Napoli, Italy.

The application of social networks in the health domain has become increasingly prevalent. They are web-based technologies which bring together a group of people and health-care providers having in common health-related interests, who share text, image, video and audio contents and interact with each other. This explains the increasing amount of attention paid to this topic by researchers who have investigated a variety of issues dealing with the specific applications in the health-care industry. Read More

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Sawdust for the Removal of Heavy Metals from Water: A Review.

Molecules 2021 Jul 16;26(14). Epub 2021 Jul 16.

Department of Chemistry, International Hellenic University, 65404 Kavala, Greece.

The threat of the accumulation of heavy metals in wastewater is increasing, due to their abilities to inflict damage to human health, especially in the past decade. The world's environmental agencies are trying to issue several regulations that allow the management and control of random disposals of heavy metals. Scientific studies have heavily focused on finding suitable materials and techniques for the purification of wastewaters, but most solutions have been rejected due to cost-related issues. Read More

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