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Anaesthesiology in China: A cross-sectional survey of the current status of anaesthesiology departments.

Lancet Reg Health West Pac 2021 Jul 17;12:100166. Epub 2021 Jun 17.

Anaesthesia and Operation Centre, First Medical Centre of Chinese PLA General Hospital, Beijing, 100853, China.

Background: The discipline of anaesthesiology in China has undergone historical changes and development during the past century. However, nationwide comprehensive data on the current status of each hospital department providing anaesthesia care has been lacking since the discipline was first established in China. This information is essential for effective regulation of healthcare policies by both the professional associations and the government health ministry. Read More

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The Chinese Government's Response to the Pandemic: Measures, Dynamic Changes, and Main Patterns.

Healthcare (Basel) 2021 Aug 8;9(8). Epub 2021 Aug 8.

School of Economics and Management, Fuzhou University, Fuzhou 350108, China.

(1) Background: The governance measures that governments deploy vary substantially across countries and even within countries; there is, however, limited knowledge of the responses of local governments or from different areas in the same country. (2) Methods: By using grounded theory and an automatic text processing method, this study analyses the pandemic governance measures, the pandemic governance pattern, and possible factors across 28 provinces in mainland China based on the text of 28 official provincial government Sina microblogs dating from 20 January to 1 July 2020. (3) Results and discussion: The provincial pandemic governance patterns in China are divided into a pathogen-control pattern, a diagnosis and treatment consolidation pattern, a balanced promotion pattern, a quick-adjustment response pattern, and a recovery-oriented pattern. Read More

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Knockout of the Cannabinoid Receptor 2 Gene Promotes Inflammation and Hepatic Stellate Cell Activation by Promoting A20/Nuclear Factor-κB (NF-κB) Expression in Mice with Carbon Tetrachloride-Induced Liver Fibrosis.

Med Sci Monit 2021 Aug 20;27:e931236. Epub 2021 Aug 20.

Center for Clinical Laboratories, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China (mainland).

BACKGROUND This study aimed to investigate the effect of deleting the cannabinoid receptor 2 (CB2) gene on the development of hepatic fibrosis induced by carbon tetrachloride (CCl₄) in mice via regulating inflammation. MATERIAL AND METHODS The DNA was extracted from the tails of mice to identify whether the cannabinoid receptor 2 gene was successfully knocked out. A liver fibrosis model was established by an intraperitoneal injection of CCl₄ into mice. Read More

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Seasonal and geographic variation in packed cell volume and selected serum chemistry of platypuses.

Sci Rep 2021 Aug 5;11(1):15932. Epub 2021 Aug 5.

Centre for Ecosystem Science, School of Biological, Earth & Environmental Sciences, UNSW, Sydney, NSW, 2052, Australia.

Platypuses (Ornithorhynchus anatinus) inhabit the permanent rivers and creeks of eastern Australia, from north Queensland to Tasmania, but are experiencing multiple and synergistic anthropogenic threats. Baseline information of health is vital for effective monitoring of populations but is currently sparse for mainland platypuses. Focusing on seven hematology and serum chemistry metrics as indicators of health and nutrition (packed cell volume (PCV), total protein (TP), albumin, globulin, urea, creatinine, and triglycerides), we investigated their variation across the species' range and across seasons. Read More

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Molecular epidemiologic study of citrin deficiency by screening for four reported pathogenic SLC25A13 variants in the Shaanxi and Guangdong provinces, China.

Transl Pediatr 2021 Jun;10(6):1658-1667

Department of Pediatrics, the First Affiliated Hospital, Jinan University, Guangzhou, China.

Background: Citrin deficiency (CD) is an autosomal recessive disease resulting from biallelic mutations of the gene. This study aimed to investigate the molecular epidemiological features of CD in the Guangdong and Shaanxi provinces of China.

Methods: A total of 3,409 peripheral blood samples from Guangdong and 2,746 such samples from Shaanxi province were collected. Read More

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Economic status and catastrophic health expenditures in China in the last decade of health reform: a systematic review and meta-analysis.

BMC Health Serv Res 2021 Jun 24;21(1):600. Epub 2021 Jun 24.

Department of Health Policy and Management, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.

Background: In order to solve the problem of "expensive medical treatment and difficult medical treatment" for patients and improve the equity of medical services, China started the health-care reform in 2009, and proposed ambitious goals of providing fair and high-quality basic medical and health services to all citizens and reducing economic burden of diseases. This study was to systematically explore the association between population economic status and incidence of catastrophic health expenditures (CHE) in mainland China in the last decade since 2009 health reform.

Methods: This systematic review was reported according to the standard of preferred reporting items for systematic reviews and meta-analyses (PRISMA). Read More

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A Comparison of Candida Detection in Sputum by the Conventional Culture and Fluorescent Polymerase Chain Reaction Methods.

Med Sci Monit 2021 Jun 23;27:e930293. Epub 2021 Jun 23.

Clinical Laboratory Center, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China (mainland).

BACKGROUND Candida is a pathogenic fungus. In recent years, the increase in immunosuppressive diseases has led to an increase in Candida infections, with the lungs being the most common site. Therefore, the aim of this study was to compare the positive detection rates of Candida in sputum samples by Candida culture and fluorescent polymerase chain reaction (PCR), and to explore a new method for rapid, accurate, and effective detection of Candida in sputum, providing swift evidence of clinical fungal infection. Read More

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Dispersal ability, habitat characteristics, and sea-surface circulation shape population structure of Cingula trifasciata (Gastropoda: Rissoidae) in the remote Azores Archipelago.

BMC Ecol Evol 2021 06 22;21(1):128. Epub 2021 Jun 22.

Institute for Integrative Nature Conservation Research, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.

Background: In the marine realm, dispersal ability is among the major factors shaping the distribution of species. In the Northeast Atlantic Ocean, the Azores Archipelago is home to a multitude of marine invertebrates which, despite their dispersal limitations, maintain gene flow among distant populations, with complex evolutionary and biogeographic implications. The mechanisms and factors underlying the population dynamics and genetic structure of non-planktotrophic gastropods within the Azores Archipelago and related mainland populations are still poorly understood. Read More

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Effect of Emerging Major Infectious Diseases on Sleep Quality of Medical Workers: Findings from Medical Workers Providing Support During the COVID-19 Pandemic.

Med Sci Monit 2021 Jun 12;27:e931881. Epub 2021 Jun 12.

Department of Health Services Management, School of Health Services Management, Anhui Medical University, Hefei, Anhui, China (mainland).

BACKGROUND The coronavirus disease 2019 (COVID-19) outbreak has exerted immense pressure on medical systems in China and abroad. This study aimed to compare the sleep quality of medical personnel conscripted to the Wuhan Union Cancer Centre to offer support during the early stages of the COVID-19 pandemic to the sleep quality of those who remained at Anhui Medical University Hospital and to determine the role of interventions in improving sleep quality. MATERIAL AND METHODS Questionnaires were completed by 369 individuals who were conscripted to support Wuhan (N=137) and others who were not (the control group; N=232). Read More

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Influence of Authentic Leadership on Employees' Taking Charge Behavior: The Roles of Subordinates' and Perspective Taking.

Front Psychol 2021 25;12:626877. Epub 2021 May 25.

School of Business, Nanjing University, Nanjing, China.

How to motivate employees to break through the role constraints and show more initiative determines the success or failure of a company's future development. Taking charge behavior refers to the behavior where individuals influence the change of organizational function through voluntary and constructive efforts, which is a challenging organizational citizenship behavior. This study investigates the underlying mechanism and boundary condition of authentic leadership (AL) on employees' taking charge behavior based on the role identity theory and literature concerning perspective taking. Read More

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Daily Reciprocity and Well-being: A Diary Study of Intergenerational Support between Mothers and Adult Children during the COVID-19 Pandemic.

J Gerontol B Psychol Sci Soc Sci 2021 Jun 2. Epub 2021 Jun 2.

The Chinese University of Hong Kong, Shatin, Hong Kong, China.

Objectives: Intergenerational support between aging parents and adult children is important to the well-being of both groups, especially during public health emergencies. However, few previous studies have examined the effects of daily support between parents and children on their well-being during public health emergencies. To fill in this gap, we examined the association between daily support and well-being in mothers and their adult children during the COVID-19 pandemic. Read More

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Moral injury in Chinese health professionals during the COVID-19 pandemic.

Psychol Trauma 2021 May 27. Epub 2021 May 27.

Department of Infectious Disease.

Caring for patients during the COVID-19 pandemic has placed considerable stress on health care professionals (HCPs), increasing their risk of moral injury (MI) and clinician burnout. The present study sought to examine the prevalence and correlates of MI among physicians and nurses in mainland China during the pandemic. A cross-sectional study was performed via an online survey conducted from March 27, 2020 to April 26, 2020. Read More

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Serial intervals and case isolation delays for COVID-19: a systematic review and meta-analysis.

Clin Infect Dis 2021 May 26. Epub 2021 May 26.

WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.

Background: Estimates of the serial interval distribution contribute to our understanding of the transmission dynamics of coronavirus disease 2019 (COVID-19). Here, we aimed to summarize the existing evidence on serial interval distributions and delays in case isolation for COVID-19.

Methods: We conducted a systematic review of the published literature and preprints in PubMed on two epidemiological parameters namely serial intervals and delay intervals relating to isolation of cases for COVID-19 until 22 October, 2020 following predefined eligibility criteria. Read More

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Identification of a DNA Methylation-Based Prognostic Signature for Patients with Triple-Negative Breast Cancer.

Med Sci Monit 2021 May 18;27:e930025. Epub 2021 May 18.

Department of Breast Surgery, Capital Medical University Electric Power Teaching Hospital, Beijing, China (mainland).

BACKGROUND Aberrant DNA methylation is an important biological regulatory mechanism in malignant tumors. However, it remains underutilized for establishing prognostic models for triple-negative breast cancer (TNBC). MATERIAL AND METHODS Methylation data and expression data downloaded from The Cancer Genome Atlas (TCGA) were used to identify differentially methylated sites (DMSs). Read More

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Development of Chinese mental health first aid guidelines for problem drinking: a Delphi expert consensus study.

BMC Psychiatry 2021 05 17;21(1):254. Epub 2021 May 17.

Centre for Mental Health, Melbourne School of Population and Global Health, University of Melbourne, 207 Bouverie Street, Carlton, VIC, 3053, Australia.

Background: Alcohol use disorders have become the second leading cause of death for mental and substance use disorders in China. However, with early diagnosis and timely treatment, the burden can be mitigated. Family and friends of a person with alcohol use problems are well placed to recognize the signs, encourage professional help-seeking and help the person until treatment is received. Read More

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Revisiting density-dependent fecundity in schistosomes using sibship reconstruction.

PLoS Negl Trop Dis 2021 05 13;15(5):e0009396. Epub 2021 May 13.

Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, United Kingdom.

The stability of parasite populations is regulated by density-dependent processes occurring at different stages of their life cycle. In dioecious helminth infections, density-dependent fecundity is one such regulatory process that describes the reduction in egg production by female worms in high worm burden within-host environments. In human schistosomiasis, the operation of density-dependent fecundity is equivocal and investigation is hampered by the inaccessibility of adult worms that are located intravascularly. Read More

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International Society of Nephrology Global Kidney Health Atlas: structures, organization and services for the management of kidney failure in North and East Asia.

Kidney Int Suppl (2011) 2021 May 12;11(2):e77-e85. Epub 2021 Apr 12.

Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.

Kidney failure (KF) is a public health problem in all regions of the world. We aim to provide comprehensive information regarding the disease burden of KF and capacity for providing optimal care in the International Society of Nephrology North and East Asia region based on data from the International Society of Nephrology Global Kidney Health Atlas project. Seven of eight jurisdictions participated, and wide variation was found in terms of KF burden and care capacity. Read More

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Ecological Opportunity from Innovation, not Islands, Drove the Anole Lizard Adaptive Radiation.

Syst Biol 2021 May 6. Epub 2021 May 6.

Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA.

Islands are thought to facilitate adaptive radiation by providing release from competition and predation. Anole lizards are considered a classic example of this phenomenon: different ecological specialists ('ecomorphs') evolved in the Caribbean Greater Antilles (Cuba, Hispaniola, Jamaica, and Puerto Rico), resulting in convergent assemblages that are not observed in mainland Latin America. Yet, the role of islands in facilitating adaptive radiation is more often implied than directly tested, leaving uncertain the role of biogeography in stimulating diversification. Read More

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Current Status of Ultrasound in Acute Rejection After Renal Transplantation: A Review with a Focus on Contrast-Enhanced Ultrasound.

Ann Transplant 2021 May 4;26:e929729. Epub 2021 May 4.

Department of Nephrology, Chongqing Southwest Hospital, Chongqing, China (mainland).

Renal transplantation has developed into the best treatment for end-stage renal disease, but severe cases can even lead to loss of renal allograft function due to rejection and complications caused by surgical procedures. If a series of postoperative complications can be reduced or even avoided, the quality of life of recipients will be significantly improved. Acute rejection in a transplanted kidney is one of the main complications after renal transplantation. Read More

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Transition shock, preceptor support and nursing competency among newly graduated registered nurses: A cross-sectional study.

Nurse Educ Today 2021 Jul 7;102:104891. Epub 2021 Apr 7.

Nursing Department, The Second Hospital, Cheeloo College of Medicine, Shandong University, No. 247 Beiyuan Street, Jinan City, Shandong Province 250033, PR China. Electronic address:

Background: Transition shock is highly prevalent among newly graduated registered nurses in their early career. Preceptors are widely used to support them in acquiring clinical nursing competencies and to promote their successful transition to practice. However, the mechanism by which transition shock and preceptor support are linked to nursing competency among newly graduated registered nurses remains unknown. Read More

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How much healthcare is wasted? A cross-sectional study of outpatient overprovision in private-for-profit and faith-based health facilities in Tanzania.

Health Policy Plan 2021 Jun;36(5):695-706

Department of Global Health and Development, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London WC1H 9SH, UK.

Overprovision-healthcare whose harm exceeds its benefit-is of increasing concern in low- and middle-income countries, where the growth of the private-for-profit sector may amplify incentives for providing unnecessary care, and achieving universal health coverage will require efficient resource use. Measurement of overprovision has conceptual and practical challenges. We present a framework to conceptualize and measure overprovision, comparing for-profit and not-for-profit private outpatient facilities across 18 of mainland Tanzania's 22 regions. Read More

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Fine-Scale Space-Time Cluster Detection of COVID-19 in Mainland China Using Retrospective Analysis.

Int J Environ Res Public Health 2021 03 30;18(7). Epub 2021 Mar 30.

State Key Laboratory of Remote Sensing Science, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing 100101, China.

Exploring spatio-temporal patterns of disease incidence can help to identify areas of significantly elevated or decreased risk, providing potential etiologic clues. The study uses the retrospective analysis of space-time scan statistic to detect the clusters of COVID-19 in mainland China with a different maximum clustering radius at the family-level based on case dates of onset. The results show that the detected clusters vary with the clustering radius. Read More

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Performance of Cell-Free DNA Screening for Fetal Common Aneuploidies and Sex Chromosomal Abnormalities: A Prospective Study from a Less Developed Autonomous Region in Mainland China.

Genes (Basel) 2021 03 25;12(4). Epub 2021 Mar 25.

Birth Defects Prevention and Control Institute of Guangxi Zhuang Autonomous Region, Nanning 530000, China.

To evaluate the performance of noninvasive prenatal screening (NIPS) in the detection of common aneuploidies in a population-based study, a total of 86,262 single pregnancies referred for NIPS were prospectively recruited. Among 86,193 pregnancies with reportable results, follow-up was successfully conducted in 1160 fetuses reported with a high-risk result by NIPS and 82,511 cases (95.7%) with a low-risk result. Read More

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Hemodialysis nurse burnout in 31 provinces in mainland China: A cross-sectional survey.

Hemodial Int 2021 Mar 21. Epub 2021 Mar 21.

Department of Nephrology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

Introduction: Job burnout is an occupational psychological syndrome with a high prevalence among nurses in China. Hemodialysis (HD) nursing work has the characteristics of high intensity, high technical content, and high risk. The aims of this study were to investigate the prevalence and level of job burnout among HD nurses in China and explore the potential factors associated with burnout among HD nurses. Read More

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Genitalia-related nursing embarrassment and its associated factors among female nurses in mainland China: a nationwide cross-sectional study.

Ann Transl Med 2021 Feb;9(3):191

Urology Department, Peking University People's Hospital, Beijing, China.

Background: Genital-related care is a common nursing procedure and may cause embarrassment for nurses. However, nurses' level of embarrassment and the factors associated with embarrassment have been scarcely studied. Therefore, a cross-sectional study was conducted to investigate genitalia-related care's embarrassment and its associated factors among Chinese female nurses. Read More

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February 2021

An Exploration of the Challenges for Oncology Nurses in Providing Hospice Care in Mainland China: A Qualitative Study.

Asia Pac J Oncol Nurs 2021 Mar-Apr;8(2):139-146. Epub 2021 Jan 29.

Faculty of Nursing, University of Manitoba, Winnipeg, Manitoba, Canada.

Objective: Although there has been an increasing emphasis on assisting nurses with providing quality hospice care to patients and family members, few studies have explored the challenges that oncology nurses face when delivering hospice care in the Chinese cultural context. The objective of this study was to elucidate the challenges for oncology nurses in providing hospice care for terminally ill cancer patients in mainland China.

Methods: A descriptive qualitative study with purposive sampling using audio-recorded fact-to-face interviews. Read More

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January 2021

Effects of cognitive bias modification for interpretation on hostile interpretation bias and self-reported aggression in juvenile delinquents.

Int J Clin Health Psychol 2021 May-Aug;21(2):100226. Epub 2021 Feb 14.

Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Key Laboratory of Human Development and Mental Health of Hubei Province, School of Psychology, Central China Normal University, China.

Background/objective: The social information processing model holds that aggressive behavior is closely related to the hostile interpretation of ambiguous social cues, suggesting the possibility that an intervention that reduces hostile interpretations could reduce aggression. This study in Mainland China evaluated the remediating effects of cognitive bias modification for interpretation (CBM-I) on the hostile interpretation bias and self-reported aggressive behaviors of male juvenile delinquents, taking into account initial hostile interpretation bias as a possible moderator of the intervention effect.

Method: Fifty-six male juvenile delinquents aged 16-18 were recruited and randomly assigned to the CBM-I group ( = 28) or the Waiting-List group ( = 28). Read More

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February 2021

The spatio-temporal distribution of COVID-19 infection in England between January and June 2020.

Epidemiol Infect 2021 03 8;149:e73. Epub 2021 Mar 8.

National Infection Service, Public Health England, London, UK.

The spatio-temporal dynamics of an outbreak provide important insights to help direct public health resources intended to control transmission. They also provide a focus for detailed epidemiological studies and allow the timing and impact of interventions to be assessed.A common approach is to aggregate case data to administrative regions. Read More

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Bioactive Compounds in Duval-Jouve: A Mediterranean Edible Euhalophyte.

Foods 2021 Feb 12;10(2). Epub 2021 Feb 12.

Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.

Many halophytes have great nutritional and functional potential, providing chemical compounds with biological properties. Duval-Jouve is a common euhalophyte from saline Mediterranean territories (Spain, Portugal, France, and Italy). In the present work we quantified for the first time the bioactive compounds in (total phenolic compounds and fatty acids), from Iberian Peninsula localities: littoral-coastal Tinto River basin areas (southwest Spain, the Huelva province), and mainland continental territories (northwest and central Spain, the Valladolid and Madrid provinces). Read More

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February 2021