J Clin Endocrinol Metab 2015 Apr 6;100(4):E601-6. Epub 2015 Feb 6.
Division of Reproductive Science in Medicine, Department of Obstetrics and Gynecology (P.Y., M.O., M.B.M., J.S.C.V., A.N., D.M., M.T.D., S.A.D., S.S.M., W.Q., D.C., J.J.K., S.E.B.), Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611; and Department of Molecular and Cellular Biochemistry (V.A.S.), The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210.
Context: Uterine leiomyoma is the most common benign tumor in reproductive-age women. Using a dye-exclusion technique, we previously identified a side population of leiomyoma cells exhibiting stem cell characteristics. However, unless mixed with mature myometrial cells, these leiomyoma side population cells did not survive or grow well in vitro or in vivo. Read More