301 results match your criteria main circumstance

Effect of heat input on interfacial characterization of the butter joint of hot-rolling CP-Ti/Q235 bimetallic sheets by Laser + CMT.

Sci Rep 2021 May 11;11(1):10020. Epub 2021 May 11.

Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.

Composite structures made of 2 mm-thick titanium and 10 mm-thick carbon steel are widely used in infrastructures such as long-distance gas transportation. However, cracking, which is caused by intermetallic compounds (ICs), is a dominate failure mode in welds of this structure. Thus, a common way to improve the in-service life of is reduce the number of ICs. Read More

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Improving functional form in cross-sectional regression studies to capture the non-linear safety effects of roadway attributes-Freeway median width case study.

Accid Anal Prev 2021 Jun 19;156:106130. Epub 2021 Apr 19.

Persaud and Lyon, Inc., Ottawa, ON, K2A 2Y9, Canada. Electronic address:

Crash modification factors (CMFs) for several roadway attributes are based on cross-sectional regression models, in the main because of the lack of data for the preferred observational before-after study. In developing these models, little attention has been paid to those functional forms that reflect the reality that CMFs should not be single-valued, as most available ones are, but should vary with application circumstance. Using a full Bayesian Markov Chain Monte Carlo (MCMC) approach, this study aimed to improve the functional forms used to derive CMFs in cross-sectional regression models, with a focus on capturing the variability inherent in crash modification functions (CMFunctions). Read More

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Stability analysis of SEIR model related to efficiency of vaccines for COVID-19 situation.

Heliyon 2021 Apr 15;7(4):e06812. Epub 2021 Apr 15.

Division of Mathematics and Statistics, School of Science, Walailak University, Nakhon Si Thammarat, Thailand.

This work is aimed to formulate and analyze a mathematical modeling, model, for COVID-19 with the main parameters of vaccination rate, effectiveness of prophylactic and therapeutic vaccines. Global and local stability of the model are investigated and also numerical simulation. Local stability of equilibrium points are classified. Read More

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Treatment related problems in Jordanian hemodialysis patients.

Int J Clin Pharm 2021 Mar 21. Epub 2021 Mar 21.

Clinical Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.

Background Treatment related problems are any event or circumstance involving patient treatment that actually or potentially interferes with an optimum outcome for a patient. Hemodialysis patients have on average 5-6 comorbid conditions and require 8-12 medications each day making them vulnerable to treatment related problems. Objective This study aimed to investigate treatment related problems affecting Jordanian hemodialysis patients, as well as assessing the factors associated with them. Read More

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Diet-induced obesity in animal models: points to consider and influence on metabolic markers.

Diabetol Metab Syndr 2021 Mar 18;13(1):32. Epub 2021 Mar 18.

Department of Nutrition, Food Science and Physiology, Center for Nutrition Research, University of Navarra, Pamplona, Spain.

Overweight and obesity are a worldwide public health problem. Obesity prevalence has increased considerably, which indicates the need for more studies to better understand these diseases and related complications. Diet induced-obesity (DIO) animal models can reproduce human overweight and obesity, and there are many protocols used to lead to excess fat deposition. Read More

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The Autotrophic Core: An Ancient Network of 404 Reactions Converts H, CO, and NH into Amino Acids, Bases, and Cofactors.

Microorganisms 2021 Feb 23;9(2). Epub 2021 Feb 23.

Department of Biology, Institute for Molecular Evolution, Heinrich-Heine-University of Düsseldorf, 40225 Düsseldorf, Germany.

The metabolism of cells contains evidence reflecting the process by which they arose. Here, we have identified the ancient core of autotrophic metabolism encompassing 404 reactions that comprise the reaction network from H, CO, and ammonia (NH) to amino acids, nucleic acid monomers, and the 19 cofactors required for their synthesis. Water is the most common reactant in the autotrophic core, indicating that the core arose in an aqueous environment. Read More

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February 2021

Insidious coronary artery disease in a young patient with polyarteritis nodosa: a case report and literature review.

BMC Cardiovasc Disord 2021 Feb 27;21(1):115. Epub 2021 Feb 27.

Department of Rheumatology and Clinical Immunology, Peking University First Hospital, No. 8, Xishiku Street, West District, Beijing, 100034, China.

Background: Polyarteritis nodosa (PAN) is a relatively rare systemic necrotizing vasculitis that typically affects medium-sized arteries. Although myocardial ischemia may occur due to involvement of the coronary arteries, overt myocardial infarction is uncommon. Case presentation A 22-year-old Chinese man experiencing chest pain for 7 months was admitted to our hospital. Read More

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February 2021

Climate change: how it impacts the emergence, transmission, resistance and consequences of viral infections in animals and plants.

Crit Rev Microbiol 2021 May 11;47(3):307-322. Epub 2021 Feb 11.

Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.

The ongoing COVID-19 pandemic has made us wonder what led to its occurrence and what can be done to avoid such events in the future. As we document, one changing circumstance that is resulting in the emergence and changing the expression of viral diseases in both plants and animals is climate change. Of note, the rapidly changing environment and weather conditions such as excessive flooding, droughts, and forest fires have raised concerns about the global ecosystem's security, sustainability, and balance. Read More

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Patients' Preferences for Artificial Intelligence Applications Versus Clinicians in Disease Diagnosis During the SARS-CoV-2 Pandemic in China: Discrete Choice Experiment.

J Med Internet Res 2021 02 23;23(2):e22841. Epub 2021 Feb 23.

Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.

Background: Misdiagnosis, arbitrary charges, annoying queues, and clinic waiting times among others are long-standing phenomena in the medical industry across the world. These factors can contribute to patient anxiety about misdiagnosis by clinicians. However, with the increasing growth in use of big data in biomedical and health care communities, the performance of artificial intelligence (Al) techniques of diagnosis is improving and can help avoid medical practice errors, including under the current circumstance of COVID-19. Read More

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February 2021

A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma.

Int J Surg Case Rep 2020 11;77:483-485. Epub 2020 Nov 11.

Department of Urology, Hospital La Rabta, 1007, Tunis, Tunisia.

Introduction: Metastatic prostate cancer is a relatively common condition in elderly men. The aim of this paper is to report a rare case of metastatic prostate cancer presenting as a large pelvic mass mimicking lymphoma and to discuss its management.

Presentation Of Case: An 85-year-old patient was complaining of lower urinary tract symptoms, and significant pelvic swelling. Read More

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November 2020

Analysis of Heart rate Variability and Implication of Different Factors on Heart Rate Variability.

Curr Cardiol Rev 2020 Dec 31. Epub 2020 Dec 31.

Department of Clinical Immunology, Allergology and Microbiology, Karaganda Medical University, Karaganda,. Kazakhstan.

Background: The heart is the central organ of the circulatory system which maintains the flow of blood along with the transport of nutrients to different cells and tissues. A well-functioning cardiac state is a complicated mode of changeability. A healthy heart is not only about oscillation as the rhythmometer is not the same in every circumstance. Read More

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December 2020

Observational cohort study with internal and external validation of a predictive tool for identification of children in need of hospital admission from the emergency department: the Paediatric Admission Guidance in the Emergency Department (PAGE) score.

BMJ Open 2020 12 31;10(12):e043864. Epub 2020 Dec 31.

SAPPHIRE Group, Health Sciences, University of Leicester, Leicester, UK

Objectives: To devise an assessment tool to aid discharge and admission decision-making in relation to children and young people in hospital urgent and emergency care facilities, and thereby improve the quality of care that patients receive, using a clinical prediction modelling approach.

Design: Observational cohort study with internal and external validation of a predictive tool.

Setting: Two general emergency departments (EDs) and an urgent care centre in the North of England. Read More

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December 2020

Barriers and facilitators faced by athletic trainers implementing NATA-IATF preseason heat-acclimatization guidelines in United States high school football.

J Athl Train 2020 Nov 5. Epub 2020 Nov 5.

2. Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Context: The National Athletic Trainers' Association Inter-Association Task Force (NATA-IATF) preseason heat acclimatization guidelines aim to acclimatize high school athletes to the environment during the first two weeks of the preseason and reduce risk of exertional heat illness.

Objective: Identify barriers and facilitators that high school athletic trainers encountered when implementing NATA-IATF guidelines.

Design: This qualitative investigation included a consensual qualitative research tradition/framework based in phenomenology and grounded theory. Read More

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November 2020

Thrombolysis Following Central Venous Catheter Placement.

J Stroke Cerebrovasc Dis 2020 Nov 2;29(11):105267. Epub 2020 Sep 2.

Department of Neurology, Jikei University Kashiwa Hospital, 163-1 Kashiwashita, Kashiwa-shi, Chiba 277-8567 Chiba, Japan.

Thrombolytic agents are infusion formulations, and some patients cannot be cannulated by a peripheral venous route. This report describes a patient with acute ischemic stroke who was administered alteplase following central venous catheter placement. An 82-year-old man with paroxysmal atrial fibrillation presented with left unilateral spatial neglect and left hemiparesis. Read More

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November 2020

How achievable are COVID-19 clinical trial recruitment targets? A UK observational cohort study and trials registry analysis.

BMJ Open 2020 10 5;10(10):e044566. Epub 2020 Oct 5.

Department of Medicine, University of Cambridge, Cambridge, UK

Objectives: To analyse enrolment to interventional trials during the first wave of the COVID-19 pandemic in England and describe the barriers to successful recruitment in the circumstance of a further wave or future pandemics.

Design: We analysed registered interventional COVID-19 trial data and concurrently did a prospective observational study of hospitalised patients with COVID-19 who were being assessed for eligibility to one of the RECOVERY, C19-ACS or SIMPLE trials.

Setting: Interventional COVID-19 trial data were analysed from the clinicaltrials. Read More

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October 2020

The main factors affecting Taiwan's economic growth rate via dynamic grey relational analysis.

PLoS One 2020 5;15(10):e0240065. Epub 2020 Oct 5.

Department of Industrial Management, I-Shou University, Kaohsiung, Taiwan.

Ever since the grey system theory was proposed about 40 years ago, its characteristics such as small samples, few data, and uncertainty have been used for study in the literature with increasingly wider scope. Recent studies on grey relation analysis have included static data analyses, and most of them have adopted initial values with only a relational order. Under the same study conditions, if different data preprocessing methods are used, then the relational order will be ranked differently. Read More

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November 2020

Influencing factors for peripheral and posterior lesions in mild non-proliferative diabetic retinopathy-the Kailuan Eye Study.

Int J Ophthalmol 2020 18;13(9):1467-1476. Epub 2020 Sep 18.

Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Aim: To explore the influencing factors of diabetes type 2 patients with mild non-proliferative diabetic retinopathy (NPDR) in the Kailuan area of Tangshan, Hebei Province, China.

Methods: In this non-interventional, retrospective study, 683 patients with type 2 diabetes were included in the Kailuan Diabetic Retinopathy Study involving participants with diabetes in the community-based longitudinal Kailuan Study. Based on the undilated ultra-wide field (200°; UWF) images and partial dilated digital fundus images, the diabetic retinopathy (DR) of the surveyed population was graded. Read More

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September 2020

Perspectives of wheelchair users with spinal cord injury on fall circumstances and fall prevention: A mixed methods approach using photovoice.

PLoS One 2020 28;15(8):e0238116. Epub 2020 Aug 28.

KITE, Toronto Rehab-University Health Network, Toronto, ON, Canada.

Introduction: Wheelchair users with spinal cord injury are at a high risk of falls. However, the perspectives of wheelchair users with spinal cord injury on their fall circumstances and their preferences for fall prevention strategies/interventions remain understudied. Therefore, we aimed to: a) describe the circumstances of falls experienced by wheelchair users with spinal cord injury over a six-month period, b) explore their perspectives of why falls occurred in certain situations, and c) explore their perspectives on recommended content/structure of fall prevention strategies/interventions. Read More

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October 2020

Insights into the impact of COVID-19 on household travel and activities in Australia - The early days under restrictions.

Transp Policy (Oxf) 2020 Sep 2;96:76-93. Epub 2020 Jul 2.

Institute of Transport and Logistics Studies (ITLS), The University of Sydney Business School, Sydney, NSW, 2006, Australia.

When 2020 began, we had no idea what was to unfold globally as we learnt about the Novel-Coronavirus in Wuhan, in the Hubei province of China. As this virus spread rapidly, it became a matter of time before many countries began to implement measures to try and contain the spread of the disease. COVID-19 as it is referred to, resulted in two main approaches to fighting the viral pandemic, either through a progressive set of measures to slow down the number of identified cases designed to 'flatten the curve' over time (anticipated to be at least six months), or to attack it by the severest of measures including a total lock-down and/or herding exposure to fast track 'immunisation' while we await a vaccine. Read More

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September 2020

A randomized, double-blind water taste test to evaluate the equivalence of taste between tap water and filtered water in the Taipei metropolis.

Sci Rep 2020 08 7;10(1):13387. Epub 2020 Aug 7.

Innovation and Policy Center for Population Health and Sustainable Environment, College of Public Health, National Taiwan University, Taipei, Taiwan.

High water quality and sufficient water availability are the main concerns of water users. Promoting the efficient use of tap water can contribute to sustainable drinking water management and progress towards Sustainable Development Goals. In many metropolises, water suppliers treat municipal water with appropriate treatment processes and well-maintained distribution infrastructure. Read More

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A novel riboswitch classification based on imbalanced sequences achieved by machine learning.

PLoS Comput Biol 2020 07 20;16(7):e1007760. Epub 2020 Jul 20.

Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, China.

Riboswitch, a part of regulatory mRNA (50-250nt in length), has two main classes: aptamer and expression platform. One of the main challenges raised during the classification of riboswitch is imbalanced data. That is a circumstance in which the records of a sequences of one group are very small compared to the others. Read More

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Road safety data collection systems in Iran: A comparison based on relevant organizations.

Chin J Traumatol 2020 Oct 24;23(5):265-270. Epub 2020 Jun 24.

Department of Neurobiology, Care Sciences and Society (NVS), H1, Division of Family Medicine and Primary Care, Huddinge, Sweden.

Purpose: Various organizations and institutions are involved in road traffic injury (RTI) and crash registration such as police, forensic medicine organization, hospitals and emergency medical services. But there is a substantial uncertainty in interpreting the data, duplicated data collection and missing data in relation to RTI in most systems. This study aims to identify data sources for RTI surveillance in Iran and to explore traffic safety data source domains, data elements and detailed information by each data source. Read More

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October 2020

Multi-agent evolutionary game in the recycling utilization of construction waste.

Yongbo Su

Sci Total Environ 2020 Oct 2;738:139826. Epub 2020 Jun 2.

School of Civil Engineering and Architecture, Anyang Normal University, Anyang 455000, China. Electronic address:

The recycling utilization of construction waste (CW) is of great importance to reduce waste discharge and protect natural resources. This study investigated the evolutionary decision making process and stable strategies among three stakeholders, including the government agency (GA), waste recycler (WR) and waste producer (WP), involved in CW recycling industry based on the game theory. The main factors that affected the strategies of the stakeholders were analyzed and the tripartite evolutionary game model is provided. Read More

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October 2020

Multiple endocrinological failures as a clinical presentation of a metastatic lung adenocarcinoma.

Endocrinol Diabetes Metab Case Rep 2020 Apr 29;2020. Epub 2020 Apr 29.

Department of Endocrinology and Diabetology, Douai Hospital Center, Douai, France.

Summary: Multiple endocrine metastases are a rare but possible complication of lung adenocarcinoma (LAC). Pituitary metastasis is a rare condition with poor clinical expression. Diabetes insipidus (DI) is its most common presenting symptom. Read More

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[Retrieval of devices lost or entrapped during percutaneous coronary interventions].

G Ital Cardiol (Rome) 2020 06;21(6 Suppl 1):15S-20S

Laboratorio di Interventistica Cardiovascolare, S.C. Cardiologia, Ospedale San Giovanni Bosco, Torino.

Device loss or entrapment during percutaneous coronary interventions (PCI) is a rare circumstance whose incidence has decreased over time mainly because of device improvements. Nevertheless, they still represent fearful complications also and above all because the operators may be unfamiliar with rescue and retrieval techniques. The devices that most frequently experience loss or entrapment are stents, followed by angioplasty balloons, burrs for rotational atherectomy, guidewires and microcatheters. Read More

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ICGEC: a comparative method for measuring epigenetic conservation of genes via the integrated signal from multiple histone modifications between cell types.

BMC Genomics 2020 May 12;21(1):356. Epub 2020 May 12.

College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.

Background: Histone post-translational modifications play crucial roles in epigenetic regulation of gene expression and are known to be associated with the phenotypic differences of different cell types. Therefore, it is of fundamental importance to dissect the genes and pathways involved in such a phenotypic variation at the level of epigenetics. However, the existing comparative approaches are largely based on the differences, especially the absolute difference in the levels of individual histone modifications of genes under contrasting conditions. Read More

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Genetic Diversity of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) From 1996 to 2017 in China.

Front Microbiol 2020 24;11:618. Epub 2020 Apr 24.

Research Team on Porcine Viral Reproductive Disorder Syndrome, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.

Porcine reproductive and respiratory syndrome (PRRS) is one of the most devastating diseases of the global swine industry. The causative agent (PRRSV) was first isolated in China in 1996 and has evolved quickly during the last two decades. To fully understand virus diversity, epidemic situation in the field, and make future predictions, a total of 365 PRRSV strains were used for evolution and genome analysis in which 353 strains were isolated from mainland China. Read More

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Antipsychotic-induced Hyperprolactinemia in aging populations: Prevalence, implications, prevention and management.

Prog Neuropsychopharmacol Biol Psychiatry 2020 07 31;101:109941. Epub 2020 Mar 31.

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada, M5P 3L6.

This paper reviews the prevalence, implications, prevention and management of antipsychotic-induced hyperprolactinemia in aging populations. Antipsychotics are indicated mainly for the treatment of psychotic illness but are also used in other conditions. Complications induced by antipsychotics increase with age, due to age-related changes in drug metabolism and excretion. Read More

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Essential Oils Extracted from Different Species of the Lamiaceae Plant Family as Prospective Bioagents against Several Detrimental Pests.

Molecules 2020 Mar 28;25(7). Epub 2020 Mar 28.

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo 38-90123, Italy.

On the basis of the side effects of detrimental synthetic chemicals, introducing healthy, available, and effective bioagents for pest management is critical. Due to this circumstance, several studies have been conducted that evaluate the pesticidal potency of plant-derived essential oils. This review presents the pesticidal efficiency of essential oils isolated from different genera of the Lamiaceae family including Gronovius, Jacquin, L. Read More

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Dual responsive linalool capsules with high loading ratio for excellent antioxidant and antibacterial efficiency.

Colloids Surf B Biointerfaces 2020 Jun 17;190:110978. Epub 2020 Mar 17.

School of Chemical and Environmental Engineering, Shanghai Institute of Technology, 201418, Shanghai, PR China. Electronic address:

Linalool is a main component in different naturally derived essential oils, and widely used in household, personal care, food and therapeutic formulations. However, the application is limited due to its high volatility and low stability. In this study, an effective encapsulation with high loading ratio was built up together with thermal-redox dual responsiveness and controlled release properties. Read More

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