1,038 results match your criteria lynx

Seven decades of southern range dynamics of Canada lynx.

Ecol Evol 2021 May 9;11(9):4644-4655. Epub 2021 Mar 9.

Environmental & Life Sciences Graduate Program Trent University Peterborough ON Canada.

The range of the Canada lynx () has contracted substantially from its historical range. Using harvest records, we found that the southern range of the lynx in Ontario in the late 1940s collapsed and then, in a short period of time, increased to its largest extent in the mid-1960s when the lynx range spread south of the boreal forest for a decade. After this expansion, the southern range contracted northwards beginning in the 1970s. Read More

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Combination Immunotherapy for Hepatocellular Carcinoma: Where Are We Currently?

Semin Liver Dis 2021 May 6. Epub 2021 May 6.

Division of Hematology and Medical Oncology, Mayo Clinic, Scottsdale, Arizona.

The past decade has seen a rise in the availability of breakthrough therapeutic strategies for treatment of hepatocellular carcinoma (HCC). A tumor microenvironment in HCC is regulated by various immunotolerance mechanisms; therefore, therapeutic strategies aiming at disrupting tumor immune tolerance are becoming attractive curative options in HCC. Immune checkpoint inhibitors have demonstrated impressive effectiveness in HCC, including in sorafenib-unresponsive patients. Read More

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Unraveling the impact of plant-density genetic architecture on agronomic traits in canola.

J Exp Bot 2021 May 3. Epub 2021 May 3.

IFEVA (CONICET-UBA), Facultad de Agronomía, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.

Plant density defines vegetative architecture and competition for light between individuals. Brassica napus (canola), as a model system of indeterminate growth, presents a radically different plant architecture compared to traditional crops commonly cultivated at high density. Using a panel of 152 spring-type canola accessions and a double haploid (DH) population of 99 lines from a cross between Lynx and Monty, we performed Genome-Wide-Analysis-Studies (GWAS) and Quantitative Trait Locus (QTL) mapping for 12 growth and yield traits at two contrasting plant densities (15 and 60 plants m -2). Read More

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An apex carnivore's life history mediates a predator cascade.

Oecologia 2021 May 1. Epub 2021 May 1.

Department of Fisheries and Wildlife, Michigan State University, 480 Wilson Road, Room 13 Natural Resources Building, East Lansing, MI, 48824, USA.

Apex predators can shape communities via cascading top-down effects, but the degree to which such effects depend on predator life history traits is largely unknown. Within carnivore guilds, complex hierarchies of dominance facilitate coexistence, whereby subordinate species avoid dominant counterparts by partitioning space, time, or both. We investigated whether a major life history trait (hibernation) in an apex carnivore (black bears Ursus americanus) mediated its top-down effects on the spatio-temporal dynamics of three sympatric mesocarnivore species (coyotes Canis latrans, bobcats Lynx rufus, and gray foxes Urocyon cinereoargenteus) across a 15,000 km landscape in the western USA. Read More

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Multi-seasonal systematic camera-trapping reveals fluctuating densities and high turnover rates of Carpathian lynx on the western edge of its native range.

Sci Rep 2021 Apr 29;11(1):9236. Epub 2021 Apr 29.

Department of Forest Ecology, Faculty of Forestry and Wood Technology, Mendel University in Brno, Zemědělská 1, 613 00, Brno, Czech Republic.

Camera-trapping and capture-recapture models are the most widely used tools for estimating densities of wild felids that have unique coat patterns, such as Eurasian lynx. However, studies dealing with this species are predominantly on a short-term basis and our knowledge of temporal trends and population persistence is still scarce. By using systematic camera-trapping and spatial capture-recapture models, we estimated lynx densities and evaluated density fluctuations, apparent survival, transition rate and individual's turnover during five consecutive seasons at three different sites situated in the Czech-Slovak-Polish borderland at the periphery of the Western Carpathians. Read More

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HIV self-testing and STI self-collection via mobile apps: experiences from two pilot randomized controlled trials of young men who have sex with men.

Mhealth 2021 20;7:26. Epub 2021 Apr 20.

Bridge HIV, San Francisco Department of Public Health, San Francisco, CA, USA.

Background: Young men who have sex with men (YMSM) are disproportionately impacted by HIV and other sexually transmitted infections (STIs) in the United States (US) and have low rates of HIV/STI testing. Provision of HIV self-testing and STI self-collection can increase testing rates, and access to these kits through mobile applications (apps) could help facilitate YMSM using HIV self-testing and STI self-collection.

Methods: Data for this study comes from two pilot randomized controlled trials (RCTs) of mobile apps within the Adolescent Trials Network-LYNX and MyChoices-aimed to increase HIV/STI testing among YMSM (age 15-24) who had not recently tested for HIV and were at high risk for HIV acquisition across five US cities. Read More

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Temporomandibular Joint Pathology of Wild Carnivores in the Western USA.

Front Vet Sci 2021 8;8:657381. Epub 2021 Apr 8.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.

Skull specimens from: southern sea otter (), Eastern Pacific harbor seal (, California sea lion (, northern fur seal (), walrus (), polar bear (, North American brown bear (, American black bear , California mountain lion (), California bobcat (, gray fox (, kit fox (, and gray wolf ( ( = 5,011) were macroscopically examined for dental and temporomandibular joint (TMJ) pathology. The presence of temporomandibular joint osteoarthritis (TMJ-OA) varied across species: 4.1% of southern sea otter, 34. Read More

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Mesocarnivore landscape use along a gradient of urban, rural, and forest cover.

PeerJ 2021 6;9:e11083. Epub 2021 Apr 6.

Department of Fisheries and Wildlife, Oregon State University, Corvallis, OR, United States of America.

Mesocarnivores fill a vital role in ecosystems through effects on community health and structure. Anthropogenic-altered landscapes can benefit some species and adversely affect others. For some carnivores, prey availability increases with urbanization, but landscape use can be complicated by interactions among carnivores as well as differing human tolerance of some species. Read More

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Benign juvenile idiopathic epilepsy in captive Iberian lynx (Lynx pardinus) in the ex situ conservation program (2005-2019).

BMC Vet Res 2021 Apr 15;17(1):165. Epub 2021 Apr 15.

NeurologiaVeterinaria, Getafe, Madrid, Spain.

Background: Benign juvenile idiopathic epilepsy has been described in humans but rarely in animals. The objectives of the study were to describe the clinical signs, clinical data, imaging findings, genetic examinations, treatment, long-term outcome and prognosis in Iberian lynx with juvenile epilepsy. Medical records, video recordings and diagnostic data from 2005 to 2019 were reviewed. Read More

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In situ feeding as a new management tool to conserve orphaned Eurasian lynx (lynx lynx).

Ecol Evol 2021 Apr 2;11(7):2963-2973. Epub 2021 Mar 2.

Albert Ludwig University Freiburg Germany.

High human-caused mortality due to wildlife-vehicle-collisions and illegal killing leads to frequent cases of orphaned Eurasian lynx juveniles. Under natural conditions, this would result in starvation of the young. To avoid this, wildlife managers conventionally rear animals in captivity and release them later. Read More

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Parasites of the Reintroduced Iberian Lynx () and Sympatric Mesocarnivores in Extremadura, Spain.

Pathogens 2021 Mar 1;10(3). Epub 2021 Mar 1.

Asistencia Técnica de la Dirección General del Medio Natural y Desarrollo Sostenible de la Junta de Comunidades de Castilla-La Mancha, Plaza del Cardenal Siliceo s/n, 45071 Toledo, Spain.

The Iberian lynx () is one of the most endangered felid species in the world. Conservation efforts have increased its population size and distribution and reinforced their genetic diversity through captive breeding and reintroduction programmes. Among several threats that the Iberian lynx faces, infectious and parasitic diseases have underlined effects on the health of their newly reintroduced populations, being essential to identify the primary sources of these agents and assess populations health status. Read More

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Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC).

J Immunother Cancer 2021 Mar;9(3)

Medical Oncology, Lowe Center for Thoracic Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA

Background: Currently available biomarkers are imperfect in their ability to predict responses to the multiple first-line treatment options available for patients with advanced non-small cell lung cancer (NSCLC). Having an early pharmacodynamic marker of treatment resistance may help redirect patients onto more effective alternative therapies. We sought to determine if changes in circulating tumor DNA (ctDNA) levels after initiation of first-line pembrolizumab±chemotherapy in NSCLC would enable early prediction of response prior to radiological assessment. Read More

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Species delimitation and taxonomic revision of Oxyopes (Araneae: Oxyopidae) of Taiwan, with description of two new species.

Zootaxa 2021 Feb 11;4927(1):zootaxa.4927.1.4. Epub 2021 Feb 11.

Department of Life Science, National Taiwan Normal University, No. 88, Sec. 4, Tingzhou Rd., Taipei 11677, Taiwan Zoology Division, Taiwan Endemic Species Research Institute, No. 1, Minsheng E. Rd., Jiji Township, Nantou 55244, Taiwan..

This study revised the spider genus Oxyopes Latreille, 1804 in Taiwan and delineated the species boundaries based on morphological and molecular characters. A total of seven Oxyopes spiders were recognized, including two newly described species, O. hasta sp. Read More

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February 2021

Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium.

Ann Oncol 2021 06 19;32(6):787-800. Epub 2021 Mar 19.

Thompson Cancer Survival Center, Knoxville, USA.

Background: Patients with cancer may be at high risk of adverse outcomes from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort of patients with cancer and coronavirus 2019 (COVID-19) reported to the COVID-19 and Cancer Consortium (CCC19) to identify prognostic clinical factors, including laboratory measurements and anticancer therapies.

Patients And Methods: Patients with active or historical cancer and a laboratory-confirmed SARS-CoV-2 diagnosis recorded between 17 March and 18 November 2020 were included. Read More

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Radiation-Associated Lymphopenia and Outcomes of Patients with Unresectable Hepatocellular Carcinoma Treated with Radiotherapy.

J Hepatocell Carcinoma 2021 3;8:57-69. Epub 2021 Mar 3.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: The immune system plays a crucial role in cancer surveillance. Previous studies have shown that lymphopenia associated with radiotherapy (RT) portends a poor prognosis. We sought to differentiate the effects of proton and photon RT on changes in absolute lymphocyte count (ALC) for patients with hepatocellular carcinoma (HCC). Read More

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Disease Surveillance during the Reintroduction of the Iberian Lynx () in Southwestern Spain.

Animals (Basel) 2021 Feb 19;11(2). Epub 2021 Feb 19.

Instituto de Investigación en Recursos Cinegéticos-(CSIC-UCLM-JCCM), 13071 Ciudad Real, Spain.

The restoration of Iberian lynx () populations in Extremadura (Southwestern Spain) have been carried out since 2014. One of the measures to ensure the success of this program is to examine the effects that diseases may have on reintroduction. Since diseases may be greatly located at certain sites because of the specific ecological requirements of the pathogens and/or vectors, reintroduced individuals may present a risk of infection once released. Read More

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February 2021

Investigating ZFYVE26 mutations in a Taiwanese cohort with hereditary spastic paraplegia.

J Formos Med Assoc 2021 Feb 24. Epub 2021 Feb 24.

Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan. Electronic address:

Background/purpose: Hereditary spastic paraplegia (HSP) is a heterogeneous group of inherited neurodegenerative disorders characterized by slowly progressive lower limbs spasticity and weakness. HSP type 15 (SPG15) is an autosomal recessive subtype caused by ZFYVE26 mutations. The aim of this study was to investigate the frequency and clinical and genetic features of ZFYVE26 mutations in a Taiwanese HSP cohort. Read More

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February 2021


J Wildl Dis 2021 Jan;57(1):27-39

Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, California 95616, USA.

Leptospirosis is reported infrequently in wild and domestic felids. We estimated the prevalence of Leptospira spp. infection and exposure using real-time PCR and serology, respectively, in 136 mountain lions (Puma concolor) and 39 bobcats (Lynx rufus) that died or were euthanized between 2009 and 2017 from several regions of California, US. Read More

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January 2021

A Microphysiological Approach to Evaluate Effectors of Intercellular Hedgehog Signaling in Development.

Front Cell Dev Biol 2021 9;9:621442. Epub 2021 Feb 9.

Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, WI, United States.

Paracrine signaling in the tissue microenvironment is a central mediator of morphogenesis, and modeling this dynamic intercellular activity is critical to understanding normal and abnormal development. For example, Sonic Hedgehog (Shh) signaling is a conserved mechanism involved in multiple developmental processes and strongly linked to human birth defects including orofacial clefts of the lip and palate. SHH ligand produced, processed, and secreted from the epithelial ectoderm is shuttled through the extracellular matrix where it binds mesenchymal receptors, establishing a gradient of transcriptional response that drives orofacial morphogenesis. Read More

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February 2021

Improved prediction of Canada lynx distribution through regional model transferability and data efficiency.

Ecol Evol 2021 Feb 24;11(4):1667-1690. Epub 2021 Jan 24.

Rocky Mountain Research Station United States Forest Service Missoula MT USA.

The application of species distribution models (SDMs) to areas outside of where a model was created allows informed decisions across large spatial scales, yet transferability remains a challenge in ecological modeling. We examined how regional variation in animal-environment relationships influenced model transferability for Canada lynx (), with an additional conservation aim of modeling lynx habitat across the northwestern United States. Simultaneously, we explored the effect of sample size from GPS data on SDM model performance and transferability. Read More

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February 2021

Genetic analysis indicates spatial-dependent patterns of sex-biased dispersal in Eurasian lynx in Finland.

PLoS One 2021 19;16(2):e0246833. Epub 2021 Feb 19.

NIBIO-Division of Environment and Natural Resources, Norwegian Institute of Bioeconomy Research, Svanvik, Norway.

Conservation and management of large carnivores requires knowledge of female and male dispersal. Such information is crucial to evaluate the population's status and thus management actions. This knowledge is challenging to obtain, often incomplete and contradictory at times. Read More

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February 2021

Calibration and Testing of Small High-Resolution Transition Edge Sensor Microcalorimeters with Optical Photons.

IEEE Trans Appl Supercond 2021 Jan;1

NASA Goddard Space Flight Center, Greenbelt, MD 20771, USA.

Pulses of narrow line-width optical photons can be used to calibrate and test sub-2 eV full-width at halfmaximum (FWHM) energy resolution transition-edge sensor (TES) microcalorimeters at low energies (< 1 keV), where it is very challenging to obtain X-ray calibration lines comparable to (or narrower than) the detector resolution. This scheme depends on the ability to resolve the number of 3 eV photons in each pulse, which we have recently demonstrated up to photon numbers of about 300. At LTD-18 we showed preliminary results obtained with this technique on a 0. Read More

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January 2021

Epidemiological Study of Pesticide Poisoning in Domestic Animals and Wildlife in Portugal: 2014-2020.

Front Vet Sci 2020 14;7:616293. Epub 2021 Jan 14.

CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, Lisboa, Portugal.

Nowadays the intentional poisoning of domestic and wild animals is a crime in the European Union (EU), but as in the past the poison is still used in rural areas of a number of European countries to kill animals that were considered harmful for human activities. From January 2014 up until October 2020, the Laboratory of Pharmacology and Toxicology of the Faculty of Veterinary Medicine (LFT-FMV) has done the analytical detection of poisoning substances in 503 samples of wildlife and domestic animals and pesticides residues were found in 239 of the samples analyzed. In this retrospective study, toxicology results from domestic species (dog, cat, sheep, cows, and horses), wildlife species (red foxes, birds of prey, lynx, and wild boar), and food baits, are presented. Read More

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January 2021

Point-of-care p24 antigen detection for early infant diagnosis of HIV infection: cross-sectional and longitudinal studies in Zambia.

BMC Infect Dis 2021 Jan 26;21(1):118. Epub 2021 Jan 26.

Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St, Baltimore, MD, 21205, USA.

Background: Early infant diagnosis of HIV infection is challenging in sub-Saharan Africa, particularly in rural areas, leading to delays in diagnosis and treatment. Use of a point-of-care test would overcome many challenges. This study evaluated the validity of a novel point-of-care p24 antigen detection test (LYNX) in rural and urban settings in southern Zambia. Read More

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January 2021

Unique hip and stifle extensor muscle patterns in the Eurasian lynx, Lynx lynx (Carnivora: Felidae).

J Morphol 2021 Apr 3;282(4):553-562. Epub 2021 Feb 3.

Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

The Eurasian lynx (Lynx lynx) is a medium-sized felid, with a tendency to hunt for prey larger than itself. We studied the lynx hindlimb musculoskeletal anatomy in order to determine possible anatomical adaptations to hunting large prey. In our previous work, we had found characters of both large and small felids in the lynx forelimb. Read More

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Quantitative proteomic analysis in symptomatic and asymptomatic apical periodontitis.

Int Endod J 2021 Jun 17;54(6):834-847. Epub 2021 Feb 17.

Department of Preventive and Restorative Dentistry, Aracatuba School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.

Aim: To quantitatively and qualitatively compare the host proteomic profile in samples of symptomatic and asymptomatic apical periodontitis (AP) using nano-liquid chromatography-electron spray tandem mass spectrometry.

Methodology: Samples were obtained from 18 patients with radiographically evident AP, divided into symptomatic and asymptomatic groups (nine per group) according to clinical characteristics. After sample collection, protein extraction, purification and quantification of the samples were performed, which were analysed by reverse-phase liquid chromatography coupled to mass spectrometry. Read More

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spp. in Wild Boars (), Brown Bears (), Eurasian Lynxes () and Badgers () in Estonia, 2007-2014.

Animals (Basel) 2021 Jan 14;11(1). Epub 2021 Jan 14.

Research Group for Global Capacity Building, Division for Global Surveillance, National Food Institute, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.

In this study, we summarize findings from four wild, free-ranging host species from Estonia during 2007-2014. spp. larvae were detected in 281 (0. Read More

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January 2021

Three new species of Cytauxzoon in European wild felids.

Vet Parasitol 2021 Feb 5;290:109344. Epub 2021 Jan 5.

CEITEC VFU, University of Veterinary and Pharmaceutical Sciences of Brno, 61242, Brno, Czech Republic; Faculty of Medicine in Pilsen, Biomedical Center, Charles University, 32300, Plzeň, Czech Republic. Electronic address:

Protists of the genus Cytauxzoon infect a wide variety of wild and domestic felids worldwide. While the American Cytauxzoon felis has been well described, data on the European isolates of Cytauxzoon are still scant. The aim of the current study was to determine the genetic diversity of European Cytauxzoon spp. Read More

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February 2021

Cardiomyopathy Associated With Coronary Arteriosclerosis in Free-Ranging Eurasian Lynx ().

Front Vet Sci 2020 21;7:594952. Epub 2020 Dec 21.

Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

The Eurasian lynx (subspecies ) was reintroduced to Switzerland in the 1970's. Health monitoring of the reintroduced population started in the late 1980's. Since then, six lynx have been found affected by a myocardial disease. Read More

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December 2020

Comparison of the Morphology and Developmental Potential of Oocytes Obtained from Prepubertal and Adult Domestic and Wild Cats.

Animals (Basel) 2020 Dec 24;11(1). Epub 2020 Dec 24.

Department of Reproduction and Clinic of Farm Animals, University of Environmental Science, Grundwaldzki Square 49, 50-357 Wroclaw, Poland.

The aim of the study was to compare the morphology and developmental potential of oocytes obtained from adult and prepubertal domestic cats () and wild cats (, , , ). The average number of oocytes obtained from an adult domestic cat was 23 ± 11, which was significantly lower than from kittens (43 ± 29). A similar number of oocytes was derived from adult Pallas's cats (28 ± 8), and serval (30). Read More

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December 2020