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BMC Musculoskelet Disord 2021 Apr 16;22(1):357. Epub 2021 Apr 16.

Department of Orthopedic Surgery, Tokyo Medical and Dental University, 1 Chome-5-45 Yushima, Bunkyo City, Tokyo, 113-8510, Japan.

Background: Parkinson's disease (PD) has been found to increase the risk of postoperative complications in patients with adult spinal deformity (ASD). However, few studies have investigated this by directly comparing patients with PD and those without PD.

Methods: In this multicenter retrospective cohort study, we reviewed all surgically treated ASD patients with at least 2 years of follow-up. Read More

PLoS One 2021 16;16(4):e0249578. Epub 2021 Apr 16.

Department of Rheumatology, College of Medicine, Kyung Hee University, Seoul, Korea.

Introduction And Objective: Ankylosing spondylitis (AS) has characteristics of spinal bone bridge and fusion. Although BMD reduction in AS may be presumed to be due to spinal inflammation, this study was designed to confirm whether immobilization of the spine due to syndesmophytes is related to BMD reduction, as immobilization itself is a risk factor for BMD reduction.

Methods: Among male patients diagnosed with AS according to the modified New York criteria, those who underwent bone density tests with quantitative computed tomography (QCT) were retrospectively analyzed through a chart review. Read More

J Orthop Surg Res 2021 Apr 15;16(1):265. Epub 2021 Apr 15.

Department of Clinical Pharmacology, Na Homolce Hospital, Prague, Czech Republic.

Background: Surgical site infection (SSI) is a risk in every operation. Infections negatively impact patient morbidity and mortality and increase financial demands. The aim of this study was to analyse SSI and its risk factors in patients after thoracic or lumbar spine surgery. Read More

Spine J 2021 Apr 12. Epub 2021 Apr 12.

Department of Orthopedic Surgery, Barnes-Jewish Institute of Health, Washington University, St Louis, Missouri, USA.

Background Context: Sagittal spinopelvic alignment has been associated with patient-reported outcome measures and mechanical complication rates. Recently, it was claimed that linear numerical values of pelvic tilt and lumbar lordosis measurements may be misleading for patients that have different magnitudes of pelvic incidence. The use of "relative" measurements embedded in a weighted scoring of Global Alignment and Proportion (GAP) was proposed. Read More

J Pain 2021 Apr 12. Epub 2021 Apr 12.

Health Systems Management, Rush University, Chicago, Illinois, USA; Director of Research, American Hip Institute. Electronic address:

Lumbar spinal stenosis (LSS) causing neurogenic claudication (NC) is increasingly common with an aging population and can be associated with significant symptoms and functional limitations. We developed this guideline to present the evidence and provide clinical recommendations on non-surgical management of patients with LSS causing NC. Using the GRADE approach, a multidisciplinary guidelines panel based recommendations on evidence from a systematic review of randomized controlled trials and systematic reviews published through June 2019, or expert consensus. Read More

PLoS One 2021 15;16(4):e0249492. Epub 2021 Apr 15.

School of Physical Therapy and Rehabilitation, Ahi Evran University, Kırşehir, Turkey.

Objectives: The purpose of this study was to compare the efficacy of two different types of exercise methods in patients with adolescent idiopathic scoliosis.

Methods: In total, 28 subjects with adolescent idiopathic scoliosis with a mild curve magnitude (10°-26°) were randomly divided into two groups: the Schroth group (n = 14) and the core group (n = 14). The patients in the Schroth group were treated with supervised Schroth exercises, and the patients in the core group were treated with supervised core stabilization exercises; both groups performed the exercises for three days per week for a total of 10 weeks, and both were given additional traditional exercises to perform. Read More

Eur Spine J 2021 Apr 15. Epub 2021 Apr 15.

Department of Orthopaedic Surgery, Warren Alpert Medical School of Brown University, Alpert Medical School, Providence, Rhode Island, 1 Kettle Point Avenue, East Providence, RI, 02914, USA.

Purpose: AI algorithms have shown promise in medical image analysis. Previous studies of ASD clusters have analyzed alignment metrics-this study sought to complement these efforts by analyzing images of sagittal anatomical spinopelvic landmarks. We hypothesized that an AI algorithm would cluster preoperative lateral radiographs into groups with distinct morphology. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Apr;35(4):471-476

Department of Orthopedics, SSL Central Hospital of Dongguan City, Affiliated Shilong People's Hospital of Southern Medical University, Dongguan Guangdong, 523326, P.R.China.

Objective: To investigate the feasibility and mechanical properties of polymethyl methacrylate (PMMA) bone cement and allogeneic bone mixture to strengthen sheep vertebrae with osteoporotic compression fracture.

Methods: A total of 75 lumbar vertebrae (L -L ) of adult goats was harvested to prepare the osteoporotic vertebral body model by decalcification. The volume of vertebral body and the weight and bone density before and after decalcification were measured. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Apr;35(4):464-470

Department of Orthopedics, the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan Shandong, 250001, P.R.China.

Objective: To report an improved classification system of Kümmell's disease and its clinical application.

Methods: Based on CT and MRI, an improved classification system of Kümmell's disease was proposed in terms of the integrity of sagittal endplate, the integrity of posterior wall of vertebral body, and the degree of vertebral compression. Between January 2011 and March 2018, the improved classification system was used to evaluate and guide the treatment of 78 patients with Kümmell's disease. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Apr;35(4):458-463

Department of Spine Surgery, Luohe Central Hospital, Luohe Henan, 462000, P.R.China.

Objective: To investigate the efficacy and safety of over-bending rod reduction and fixation technique via posterior approach in the treatment of unstable fresh thoracolumbar burst fracture.

Methods: A clinical data of 27 patients with unstable fresh thoracolumbar burst fracture, who were met the inclusive criteria and admitted between January 2018 and October 2019, was retrospectively analyzed. There were 15 males and 12 females with an average age of 41. Read More

J Clin Orthop Trauma 2021 Jun 18;17:157-162. Epub 2021 Mar 18.

Mumbai Institute of Spine Surgery, Bombay Hospital and Medical Research Centre, Marine Lines, Mumbai, 400020, India.

Study Design: Retrospective study.

Objective: To evaluate and compare the outcomes of single stage surgery for Tandem Spinal Stenosis (TSS) in elderly (Age ≥65 years) and younger patients (Age <65 years).

Summary Of Background Data: Tandem spinal stenosis among elderly is common and often missed diagnosed with delayed presentation. Read More

Biomedicine (Taipei) 2020 1;10(3):45-49. Epub 2020 Sep 1.

Department of Neurosurgery, China Medical University Hospital, Taichung City, Taiwan.

Multiple myeloma is a hematopoietic cancer that is multicentric and most commonly involves the spine. Multiple myeloma with extraosseous and intradural involvement is an extremely rare condition. Here we present a rare case of spinal multiple myeloma with intracranial and spinal intradural metastasis causing lumbar spinal nerve compression. Read More

Biomedicine (Taipei) 2020 5;10(2):30-35. Epub 2020 Jun 5.

Division of Spine, Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore.

Background: Even though pedicle screw application is a common procedure, and in-spite of spine surgeons being proficient with the technique, mal-positioning of pedicle screws can still occur. We intend to determine by postoperative CT analysis, the incidence of pedicle screw breach in the thoracolumbar spine despite satisfactory intraoperative placement confirmed by fluoroscopy.

Materials And Methods: Consecutive patients diagnosed with thoracolumbar fractures who underwent open or minimally invasive posterior stabilization under fluoroscopic guidance were retrospectively reviewed. Read More

Sci Rep 2021 Apr 14;11(1):8142. Epub 2021 Apr 14.

Department of Orthopaedic Surgery and Spinal Surgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Although patients with diabetes reportedly have more back pain and worse patient-reported outcomes than those without diabetes after lumbar spine surgery, the impact of diabetes on postoperative recovery in pain or numbness in other regions is not well characterized. In this study, the authors aimed to elucidate the impact of diabetes on postoperative recovery in pain/numbness in four areas (back, buttock, leg, and sole) after lumbar spine surgery. The authors retrospectively reviewed 993 patients (152 with diabetes and 841 without) who underwent decompression and/or fixation within three levels of the lumbar spine at eight hospitals during April 2017-June 2018. Read More

BMJ Case Rep 2021 Apr 14;14(4). Epub 2021 Apr 14.

Department of Orthopaedic Surgery, Kudanzaka Hospital, Tokyo, Japan.

While the incidence of spondylodiscitis is rising because of longer life expectancy and the increasing use of immunosuppressant drug, indwelling devices and spinal surgeries, the fungal aetiology remains rare, sometimes affecting intravenous drug users. spondylodiscitis is an extremely rare complication post aortic aneurysm repair. It is potentially fatal due to the risk of aneurysm rupture and septic complications. Read More

J Orthop Surg Res 2021 Apr 14;16(1):263. Epub 2021 Apr 14.

Department of the Orthopaedic Surgery, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, China.

Objective: To investigate the effect of CT-assisted limited decompression in managing single segment A3 lumbar burst fracture.

Method: A retrospective study (January 2015-June, 2019). One hundred six cases with single-level Magerl type A3 lumbar burst fractures treated with short-segment posterior internal fixation and limited decompression. Read More

Mil Med 2021 Apr 14. Epub 2021 Apr 14.

Neurosurgery Department, Nord University Hospital, APHM, Marseille, Provence-Alpes-Côte d'Azur 13015, France.

Penetrating spinal injuries require specific neurosurgical attention. To date, there are no guidelines regarding emergency neurosurgical management of such injuries and the decision whether to operate is made individually, based on the neurological examination and the analysis of any imaging available. We report the case of a 22-year-old patient who sustained two gunshots in the thighs and one in the lumbar spine. Read More

Ann Biomed Eng 2021 Apr 13. Epub 2021 Apr 13.

Department of Movement Sciences, KU Leuven, Leuven, Belgium.

This study aims to propose a new optimization framework for solving spine kinematics based on skin-mounted markers and estimate subject-specific mechanical properties of the intervertebral joints. The approach enforces dynamic consistency in the entire skeletal system over the entire time-trajectory while personalizing spinal stiffness. 3D reflective markers mounted on ten vertebrae during spine motions were measured in ten healthy volunteers. Read More

Basic Clin Neurosci 2020 Nov-Dec;11(6):737-751. Epub 2020 Nov 1.

Centre of Precision Rehabilitation for Spinal Pain (CPR Spine), School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.

Introduction: Functional Magnetic Resonance Imaging (fMRI) methods have been used to study sensorimotor processing in the spinal cord. However, these techniques confront unwanted noises to the measured signal from the physiological fluctuations. In the spinal cord imaging, most of the challenges are consequences of cardiac and respiratory movement artifacts that are considered as significant sources of noise, especially in the thoracolumbar region. Read More

J Craniovertebr Junction Spine 2021 Jan-Mar;12(1):61-64. Epub 2021 Mar 4.

Department of Neurosurgery, University of Health Sciences, Istanbul, Turkey.

Introduction: Laminoplasty is a method used in spinal intradural tumor surgery to reduce the possibility of iatrogenic deformity. In classic laminoplasty, the interspinous, supraspinous, and ligamentum flavum integrity may be impaired, thereby creating a risk of deformity despite the laminoplasty. The aim of this study was to review the outcomes of bone-to-bone ligament preserving laminoplasty (BLP laminoplasty) technique. Read More

Indian J Urol 2021 Jan-Mar;37(1):97-98. Epub 2021 Jan 1.

Department of Urology, AIIMS, Rishikesh, Uttarakhand, India.

Emphysematous pyelonephritis (EPN) is a life-threatening infection of kidney with the presence of gas in the renal parenchyma, collecting system, and the surrounding retroperitoneum. We present a case of EPN in a diabetic patient with extension of gas into the spinal epidural space of the lumbar vertebral canal. He was managed conservatively with minimally invasive intervention along with supportive medical management and recovered well. Read More

Spinal Cord Ser Cases 2021 Apr 13;7(1):30. Epub 2021 Apr 13.

Central Institute of Orthopaedics, Vardhman Mahavir Medical College and Associated Safdarjung Hospital, New Delhi, India.

Introduction: Posterior fracture-dislocation of fifth lumbar vertebra (L5) is a rare injury pattern. Existing Aihara classification system lacks its mention.

Case Presentation: We report two cases of posterior fracture-dislocation of L5 with comminuted fracture of body that presented with cauda equina syndrome. Read More

J Orthop Surg Res 2021 Apr 13;16(1):251. Epub 2021 Apr 13.

Department of Spinal Surgery, Lishui Municipal Central Hospital, 289 Kuocang Road, Lishui, Zhejiang, 323000, People's Republic of China.

Objective: The aim of this retrospective study is to review our experience in the diagnosis and role of transforaminal percutaneous endoscopic discectomy (TPED) for symptomatic gas-filled discal cysts.

Methods: Between May 2014 and June 2017, 3 patients from Lishui Center Hospital (Lishui China), who underwent TPED for symptomatic gas-filled discal cysts, were analyzed. The clinical features, imaging findings, operative findings, and treatment outcomes are presented. Read More

J Orthop Surg Res 2021 Apr 13;16(1):252. Epub 2021 Apr 13.

Department of Thoracolumbar Spine Surgery, The Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China.

Background: Lumbar disc degeneration (LDD) is an essential pathological mechanism related to low back pain. Current research on spinal surgery focused on the sophisticated mechanisms involved in LDD, and autophagy was regarded as an essential factor in the pathogenesis.

Objectives: Our research aimed to apply a bioinformatics approach to select some candidate genes and signaling pathways in relationship with autophagy and LDD and to figure out potential agents targeting autophagy- and LDD-related genes. Read More

Spine J 2021 Apr 10. Epub 2021 Apr 10.

Department of Orthopaedic Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea. Electronic address:

Background Context: Recombinant human bone morphogenetic protein-2 (BMP-2) is the growth factor with the most striking osteoinductive performance in orthopedic operations; it is also able to induce heterotopic bone formation. However, there has been little clinical research on Escherichia coli-derived BMP-2 (E.BMP-2). Read More

Spine J 2021 Apr 10. Epub 2021 Apr 10.

Innlandet Hospital Trust, The Research Center for Age-Related Functional Decline and Disease, PO Box 68, N-2313, Ottestad, Norway.

Background Context: Criteria for success after surgical treatment of lumbar spinal stenosis (LSS) have been defined previously; however, there are no clear criteria for failure and worsening after surgery as assessed by patient-reported outcome measures (PROMs).

Purpose: We aimed to quantify changes in standard PROMs that most accurately identified failure and worsening after surgery for LSS.

Study Design /setting: Retrospective analysis of prospective national spine registry data with 12-months follow-up. Read More

Spine J 2021 Apr 10. Epub 2021 Apr 10.

Department of Orthopaedic Surgery, Whangarei Base Hospital, Whangarei, New Zealand.

Background Context: Surgical site infections (SSIs) after spinal fusion surgery increase healthcare costs, morbidity and mortality. Routine measures of obesity fail to consider site specific fat distribution.

Purpose: To assess the association between the spine adipose index and deep surgical site infection and determine a threshold value for spine adipose index that can assist in preoperative risk stratification in patients undergoing posterior instrumented lumbar fusion (PILF). Read More

Pediatr Emerg Care 2021 Apr 9. Epub 2021 Apr 9.

From the *Division of Pediatric Emergency Medicine, Rainbow Babies & Children's Hospital †Division of Pediatric Hospital Medicine, Rainbow Babies & Children's Hospital, University Hospitals Cleveland Medical Center ‡Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH.

Objectives: Injuries are the leading cause of morbidity and mortality in children ages 1 to 18 years. There are limited studies about pediatric thoracolumbar (TL) spinal injuries; the purpose of this study was to characterize TL spinal injuries among pediatric patients evaluated in US trauma centers.

Methods: This was a retrospective cohort study of the National Trauma Data Bank. Read More

Eur Spine J 2021 Apr 13. Epub 2021 Apr 13.

Department of Orthopaedics, PGIMER, Chandigarh, India.

Acta Orthop Traumatol Turc 2021 Mar;55(2):166-170

Department of orthopedic Surgery, 923nd Hospital of People's Liberation Army, Guangxi Province, China.

Objective: This study aimed to investigate the therapeutic effects of full endoscopic spine surgery on clinical and radiological outcomes in elderly patients over 70 years with lumbar spinal stenosis, without any obvious segmental instability.

Methods: A total of 47 patients (27 males, 20 females; the mean age=74.23±5. Read More