6 results match your criteria lsct boston

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Management of Congenital Aniridia-Associated Keratopathy: Long-Term Outcomes from a Tertiary Referral Center.

Am J Ophthalmol 2020 02 12;210:8-18. Epub 2019 Nov 12.

Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois, USA. Electronic address:

Purpose: To report the outcomes of medical and surgical management for congenital aniridia-associated keratopathy (AAK) over a long-term follow-up period.

Design: Retrospective, comparative case series.

Methods: Medical records of patients diagnosed with congenital aniridia were retrospectively reviewed. Read More

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February 2020

Autologous limbal stem cell transplantation: a systematic review of clinical outcomes with different surgical techniques.

Br J Ophthalmol 2020 02 22;104(2):247-253. Epub 2019 May 22.

Center for Ocular Regeneration (CORE), LV Prasad Eye Institute, Hyderabad, India

Purpose: To conduct a systematic review on outcomes of three different techniques of autologous limbal stem cell transplantation (LSCT): conjunctival-limbal autografting (CLAu), cultivated limbal epithelial transplantation (CLET) and simple limbal epithelial transplantation (SLET), in unilateral limbal stem cell deficiency (LSCD).

Methods: Literature searches were conducted in MEDLINE (Ovid), Embase, Web of Science and Cochrane Central Register. Standard systematic review methodology was followed using Meta-analysis of Observational Studies in Epidemiology guidelines. Read More

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February 2020

Limbal Stem Cell Transplantation and Complications.

Semin Ophthalmol 2018 27;33(1):134-141. Epub 2017 Nov 27.

a Massachusetts Eye and Ear, Department of Ophthalmology , Harvard Medical School , Boston , MA , USA.

Corneal epithelial stem cells are adult somatic stem cells located at the limbus and represent the ultimate source of transparent corneal epithelium. When these limbal stem cells become dysfunctional or deficient, limbal stem cell deficiency (LSCD) develops. LSCD is a major cause of corneal scarring and is particularly prevalent in chemical and thermal burns of the ocular surface. Read More

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February 2018

Visual rehabilitation with keratoprosthesis after tenonplasty as the primary globe-saving procedure for severe ocular chemical injuries.

Graefes Arch Clin Exp Ophthalmol 2012 Dec 1;250(12):1787-93. Epub 2012 May 1.

Medical & Vision Research Foundation, 18 College Road, Chennai, 600 006, Tamil Nadu, India.

Purpose: To analyze the outcome (functional and anatomic) of eyes that underwent tenonplasty as the primary globe-saving procedure in severe ocular chemical injuries (grade V-VI Dua's classification).

Methods: The records of patients who underwent tenonplasty for associated scleral ischemia in severe chemical burns in our institute between October 2005 and June 2011 were analyzed retrospectively. Out of 31 eyes that underwent tenonplasty, 21 belonged to grade V and VI of Dua's classification with diffuse scleral ischemia for which a four-quadrant tenonplasty was performed and only these 21 eyes were included for further analysis. Read More

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December 2012

Limbal stem cell transplantation in chronic inflammatory eye disease.

Ophthalmology 2002 May;109(5):862-8

Ocular Immunology and Uveitis Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.

Objective: The goal of this study was to describe the outcome of limbal stem cell transplantation (LSCT) in patients with severe ocular surface disease caused by underlying chronic inflammatory eye disease.

Design: Retrospective noncomparative case series.

Participants: Nine patients with limbal stem cell deficiency caused by an underlying ocular inflammatory disease who underwent LSCT. Read More

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Amniotic membrane surgery.

Curr Opin Ophthalmol 2001 Aug;12(4):269-81

Cornea Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.

Human amniotic membrane (AM) is composed of three layers: a single epithelial layer, a thick basement membrane, and an avascular stroma. Amniotic membrane has anti-adhesive properties and is felt to promote epithelialization and decrease inflammation, neovascularization, and fibrosis. Amniotic membrane transplantation (AMT) is currently being used for a continuously widening spectrum of ophthalmic indications. Read More

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