31,208 results match your criteria lower wall

Pelvic floor, abdominal and uterine tenderness in relation to pressure pain sensitivity among women with endometriosis and chronic pelvic pain.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 22;264:247-253. Epub 2021 Jul 22.

Departments of Anesthesiology, Critical Care, & Pain Medicine and Psychiatry, Boston Children's Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Biobehavioral Pediatric Pain Lab, Boston Children's Hospital, Boston, MA, USA. Electronic address:

Objective: Pelvic floor pain, abdominal wall pain, and central nervous system pain amplification can be contributing factors in chronic pelvic pain (CPP), however; limited research has investigated the association of pelvic floor, abdominal, and uterine tenderness with central nervous system pain amplification. We assessed whether pressure pain thresholds on the non-dominant thumbnail, a marker of central nervous system pain amplification, were associated with pelvic floor, abdominal, and uterine tenderness among women with endometriosis or CPP.

Study Design: We conducted a cross-sectional study among 88 females with endometriosis and/or CPP. Read More

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Serial assessment of inflammatory parameters for prediction of septic complications following surgery for colorectal endometriosis : A descriptive, retrospective study.

Wien Klin Wochenschr 2021 Aug 2. Epub 2021 Aug 2.

Department of Gynecology, Center for Endometriosis, Hospital St. John of God Vienna, Vienna, Austria.

Purpose: To assess whether C‑reactive protein (CRP), white blood cell count (WBC) and body temperature changes are suitable parameters for the early detection of septic complications following resection of colorectal deep endometriosis (DE).

Methods: Retrospective data analysis of CRP, WBC and body temperature courses following colorectal surgery for DE at a tertiary referral center for endometriosis.

Results: Out of 183 surgeries performed, 10 major surgical complications were observed, including 4 anastomotic leakages (AL 2%) and 2 rectovaginal fistulae (RVF 1%). Read More

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Honeymoon Period in Newborn Rats With CDH Is Associated With Changes in the VEGF Signaling Pathway.

Front Pediatr 2021 16;9:698217. Epub 2021 Jul 16.

Laboratory of Experimental Fetal Surgery, Division of Pediatric Surgery, Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.

Patients with congenital diaphragmatic hernia (CDH) have a short postnatal period of ventilatory stability called the honeymoon period, after which changes in pulmonary vascular reactivity result in pulmonary hypertension. However, the mechanisms involved are still unknown. The aim of this study was to evaluate mechanical ventilation's effect in the honeymoon period on VEGF, VEGFR-1/2 and eNOS expression on experimental CDH in rats. Read More

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Brevibacillin 2V Exerts Its Bactericidal Activity Binding to Lipid II and Permeabilizing Cellular Membranes.

Front Microbiol 2021 16;12:694847. Epub 2021 Jul 16.

Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, Netherlands.

Lipo-tridecapeptides, a class of bacterial non-ribosomally produced peptides, show strong antimicrobial activity against Gram-positive pathogens, including antibiotic-resistant and spp. However, many of these lipo-tridecapeptides have shown high hemolytic activity and cytotoxicity, which has limited their potential to be developed into antibiotics. Recently, we reported a novel antimicrobial lipo-tridecapeptide, brevibacillin 2V, which showed no hemolytic activity against human red blood cells at a high concentration of 128 mg/L, opposite to other brevibacillins and lipo-tridecapeptides. Read More

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The Effect of Vibration on Pain During Heel Lance Procedures in Newborns: A Randomized Controlled Trial.

Adv Neonatal Care 2021 Jul 30. Epub 2021 Jul 30.

Sanliurfa Birecik Cuma Gokdogan Primary Care Clinic No. 3, Turkey (Ms Avan Antepli); Department of Nursing, Faculty of Health Sciences, Gaziantep University, Gaziantep, Turkey (Dr Bilsin Kocamaz); and Department of Nursing, Faculty of Health Sciences, Gaziantep Islamic Science and Technology University, Gaziantep, Turkey (Dr Güngörmüs¸).

Background/significance: The pain-reducing effect of applying vibration, which is used as a nonpharmacological method in pain management, is explained by the gate control theory developed by Melzack and Wall. Studies that are based on this theory have shown similar results to those of Melzack and Wall, indicating that pain-transmitting nerves are suppressed by vibrations, leading to higher pain thresholds.

Purpose: The study aimed to evaluate the effect of applying vibration to manage pain during heel lance procedures in newborns. Read More

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Arterial Occlusion After Hyaluronic Acid Injection: Treatment With Hyaluronidase and Streptokinase.

Ann Plast Surg 2021 Jul 29. Epub 2021 Jul 29.

From the Departments of Plastic, Reconstructive and Aesthetic Surger Histology, Gazi University Hospital, Ankara, Turkey.

Abstract: The most feared complication of the hyaluronic acid injections in the periorbital region is embolism of the central retinal artery. The present study aimed to compare the effectiveness of hyaluronidase administered intravenously (systemically) alone or in combination with streptokinase with that of intra-arterial revascularization. Thirty rats were divided into 5 groups. Read More

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Epicardial fat thickness in infants of diabetic mothers.

J Neonatal Perinatal Med 2021 Jul 28. Epub 2021 Jul 28.

Department of Neonatology, Hospital General, Leon, Secretaria de Salud de Guanajuato, Mexico.

Background: Epicardial fat thickness (EFT) in adults and children has been related to the metabolic syndrome and other cardiovascular risk factors; however, scarce studies have evaluated it in infants of diabetic mothers (IDM) in whom, alterations in the thickness of the interventricular septum have been reported. This study compares the EFT in IDM versus infants of non-diabetic mothers (INDM) and its association with others echocardiographic parameters.

Methods: We performed a cross sectional study in 93 infants (64 IDM and 29 INDM). Read More

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Failure properties of ascending thoracic aortic aneurysms with dysfunctional tricuspid aortic valves.

Interact Cardiovasc Thorac Surg 2021 Aug 1. Epub 2021 Aug 1.

Department of Cardiac Surgery, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.

Objectives: Ascending thoracic aortic aneurysms (ATAAs) often coexist with dysfunctional tricuspid aortic valves (TAVs). How valvular pathology relates to the aortic wall mechanical properties requires detailed examination.

Methods: Intact-wall and layer-specific mechanical properties from 40 and 21 patients with TAV-ATAAs, respectively, were studied using uniaxial tensile testing, longitudinally and circumferentially. Read More

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Can ultrasound measurement of bladder wall thickness be a useful adjunct for regular urodynamics in children with spina bifida?

J Pediatr Urol 2021 Jul 13. Epub 2021 Jul 13.

Department of Renal and Genitourinary Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Introduction: Spina bifida is a major cause of neurologic bladder dysfunction among children. The goal of neurogenic bladder treatment is to preserve renal function. Close follow-up is essential, as lower urinary tract functions can change with patient growth. Read More

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Transanal approach after preoperative imatinib treatment of a rectal gastrointestinal stromal tumors with external anal sphincter invasion: A case report.

Int J Surg Case Rep 2021 Jul 19;85:106217. Epub 2021 Jul 19.

Department of Surgery, Japan Community Health Care Organization Isahaya General Hospital, Nagasaki, Japan.

Introduction And Importance: Rectal gastrointestinal stromal tumors (GISTs) are rare, and preserving anorectal function can be challenging. We report the case of a patient with rectal GIST with external anal sphincter invasion, treated via the laparoscopic and transanal approaches.

Case Presentation: A 61-year-old man with locally advanced GIST in the right anterolateral wall of the lower rectum was examined. Read More

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Antibody responses after first and second Covid-19 vaccination in patients with chronic lymphocytic leukaemia.

Blood Cancer J 2021 Jul 30;11(7):136. Epub 2021 Jul 30.

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK.

B-cell chronic lymphocytic leukaemia (CLL) is associated with immunosuppression and patients are at increased clinical risk following SARS-CoV-2 infection. Covid-19 vaccines offer the potential for protection against severe infection but relatively little is known regarding the profile of the antibody response following first or second vaccination. We studied spike-specific antibody responses following first and/or second Covid-19 vaccination in 299 patients with CLL compared with healthy donors. Read More

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Low CT attenuation and high fatty infiltration rate of psoas are risk factors for incisional hernias after appendicectomy: a cross-sectional single-center study from China.

BMC Musculoskelet Disord 2021 Jun 30;22(1):646. Epub 2021 Jun 30.

Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, 5 Jingyuan Road, Shijingshan District, Beijing, 100043, China.

Background: Decreased computed tomography (CT) attenuation of muscle is independently associated with muscle weakness. The CT attenuation of the abdominal wall muscles may correlate with that of the psoas in patients without ventral hernias. This means that the CT attenuation of the psoas may be related to the occurrence of incisional hernias (IH). Read More

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Combined video-assisted thoracoscopy surgery and posterior midline incision for en bloc resection of non-small-cell lung cancer invading the spine.

Interact Cardiovasc Thorac Surg 2021 Jul 30. Epub 2021 Jul 30.

Department of Thoracic and Vascular Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.

Objectives: This article aims to evaluate the feasibility and safety of a hybrid video-assisted thoracic surgery (VATS) approach to achieve en bloc lobectomy and spinal resection for non-small-cell lung cancer (NSCLC).

Methods: Between October 2015 and November 2020, 10 patients underwent VATS anatomical lobectomy and en bloc chest wall and spinal resection through a limited posterior midline incision as a single operation for T4 (vertebral involvement) lung cancer. Nine patients had Pancoast syndrome without vascular involvement and 1 patient had NSCLC of the right lower lobe with invasion of T9 and T10. Read More

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Surface Decoration via Physical Interaction of Cupric Diethyldithiocarbamate Nanocrystals and Its Impact on Biodistribution and Tumor Targeting.

ACS Appl Mater Interfaces 2021 Jul 30. Epub 2021 Jul 30.

College of Pharmacy, Nanjing Tech University, Nanjing 211816, China.

The vascular wall is the first physiologic barrier that circulating nanoparticles (NPs) encounter, which also is a key biological barrier to cancer drug delivery. NPs can continually scavenge the endothelium for biomarkers of cancer, and the chance of NPs' extravasation into the tumors can be enhanced. Here, we envision P-selectin as a target for specific delivery of drug nanocrystals to tumors. Read More

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High shear stress enhances endothelial permeability in the presence of the risk haplotype at 9p21.3.

APL Bioeng 2021 Sep 26;5(3):036102. Epub 2021 Jul 26.

Department of Neuroscience, The Scripps Research Institute, La Jolla, California 92037, USA.

Single nucleotide polymorphisms (SNPs) are exceedingly common in non-coding loci, and while they are significantly associated with a myriad of diseases, their specific impact on cellular dysfunction remains unclear. Here, we show that when exposed to external stressors, the presence of risk SNPs in the 9p21.3 coronary artery disease (CAD) risk locus increases endothelial monolayer and microvessel dysfunction. Read More

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September 2021

Correlation between ultrasound bladder parameters with severity of symptoms and response to treatment in patients with benign prostatic hyperplasia under medical treatment.

Am J Clin Exp Urol 2021 15;9(3):242-247. Epub 2021 Jun 15.

Assistant Professor, Department of Urology, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.

Background: Benign prostatic hyperplasia (BPH) is the most common benign mass in men, there are not standard parameter for diagnosis of BPH based on ultrasound bladder parameter, so the aim of the study was correlation between ultrasound bladder parameters with severity of symptoms and response to treatment in patients with benign prostatic hyperplasia under medical treatment.

Methods: This prospective cross-sectional study was performed on 100 men over 40 years of age with a diagnosis of BPH referred to the urology clinics of Al-Zahra and Khorshid hospitals, Isfahan, Iran in 2018-2020. The International Prostate Symptom Score (IPSS), bladder wall thickness, bladder weight, Intravesical prostatic protrusion (IPP) and response to treatment were examined before and after treatment. Read More

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Holistic Approach in the Management of Skeletal Deformity in a Case of Homocystinuria.

J Orthop Case Rep 2021 Apr;11(4):1-5

Orthopaedic Research Group, Coimbatore, Tamil Nadu, India.

Introduction: Homocystinuria has a wide range of clinical presentations ranging from near normal intelligence and appearance with just lens dislocation and minimal skeletal deformities to severe mental retardation with gross skeletal deformities. In this background, we describe one such case with skeletal deformity managed comprehensively.

Case Report: A 17-year-old boy presented with complaints of deformity of the left lower limb since childhood more evident for the past 5 years along with a history of blurring of vision. Read More

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Analysis of flow field and turbulence predictions in a lung model applying RANS and implications for particle deposition.

Eur J Pharm Sci 2021 Jul 26:105959. Epub 2021 Jul 26.

Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus.

Airflow and aerosol deposition in the human airways are important aspects for applications such as pulmonary drug delivery and human exposure to aerosol pollutants. Numerical simulations are widely used nowadays to shed light in airflow features and particle deposition patterns inside the airways. For that purpose, the Euler/Lagrange approach is adopted for predicting flow field and particle deposition through point-particle tracking. Read More

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First Performance Evaluation of an Artificial Intelligence-Based Computer-Aided Detection System for Pulmonary Nodule Evaluation in Dual-Source Photon-Counting Detector CT at Different Low-Dose Levels.

Invest Radiol 2021 Jul 28. Epub 2021 Jul 28.

From the Institute of Diagnostic and Interventional Radiology Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland Siemens Healthineers, Forchheim, Germany.

Objective: The aim of this study was to evaluate the image quality (IQ) and performance of an artificial intelligence (AI)-based computer-aided detection (CAD) system in photon-counting detector computed tomography (PCD-CT) for pulmonary nodule evaluation at different low-dose levels.

Materials And Methods: An anthropomorphic chest-phantom containing 14 pulmonary nodules of different sizes (range, 3-12 mm) was imaged on a PCD-CT and on a conventional energy-integrating detector CT (EID-CT). Scans were performed with each of the 3 vendor-specific scanning modes (QuantumPlus [Q+], Quantum [Q], and High Resolution [HR]) at decreasing matched radiation dose levels (volume computed tomography dose index ranging from 1. Read More

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Formation of Ultra-High Temperature Ceramic Hollow Microspheres as Promising Lightweight Thermal Insulation Materials via a Molten Salt-Assisted Template Method.

ACS Appl Mater Interfaces 2021 Jul 29. Epub 2021 Jul 29.

Science and Technology on Thermostructural Composite Materials Laboratory, Northwestern Polytechnical University, Xi'an 710072, China.

Ultra-high temperature ceramics (UHTCs) have become a vital candidate material system for thermal protection systems in aerospace applications. However, high thermal conductivity and high density are the main obstacles to the application of UHTCs. It is a promising solution to prepare porous UHTCs using UHTC hollow microspheres (HMs) as a pore-forming agent. Read More

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Urinary bladder augmentation with acellular biologic scaffold-A preclinical study in a large animal model.

J Biomed Mater Res B Appl Biomater 2021 Jul 29. Epub 2021 Jul 29.

Chair of Urology and Andrology, Department of Regenerative Medicine, Cell and Tissue Bank, Nicolaus Copernicus University in Torun, Ludwik Rydygier Medical College in Bydgoszcz, Bydgoszcz, Poland.

Current strategies in urinary bladder augmentation include use of gastrointestinal segments, however, the technique is associated with inevitable complications. An acellular biologic scaffold seems to be a promising option for urinary bladder augmentation. The aim of this study was to evaluate the utility of bladder acellular matrix (BAM) for reconstruction of clinically significant large urinary bladder wall defects in a long-term porcine model. Read More

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The lower respiratory airway wall in children in health and disease.

ERJ Open Res 2021 Jul 26;7(3). Epub 2021 Jul 26.

Université de Bordeaux, Centre de Recherche Cardio-Thoracique de Bordeaux, INSERM U1045, Bordeaux Imaging Center, Bordeaux, France.

Alone or in association with other lung or thorax component disorders, the airway wall (AWW) remains one of the most frequently involved elements in paediatric lung diseases. A myriad of AWW disorders will present with similar symptomatology. It is thus important for the clinician to reappraise the normal development and structure of the AWW to better understand the underlying disease patterns. Read More

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Sex Differences in Exercise-Training-Related Functional and Morphological Adaptation of Rat Gracilis Muscle Arterioles.

Front Physiol 2021 12;12:685664. Epub 2021 Jul 12.

Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary.

Background: The cardiovascular effects of training have been widely investigated; however, few studies have addressed sex differences in arteriolar adaptation. In the current study, we examined the adaptation of the gracilis arterioles of male and female rats in response to intensive training.

Methods: Wistar rats were divided into four groups: male exercise (ME) and female exercise (FE) animals that underwent a 12-week intensive swim-training program (5 days/week, 200 min/day); and male control (MC) and female control (FC) animals that were placed in water for 5 min daily. Read More

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The effect of PECS-1 block on postoperative pain in total implantable venous access port catheter (TIVAP) insertion.

J Vasc Access 2021 Jul 28:11297298211034615. Epub 2021 Jul 28.

Department of Anesthesiology and Reanimation, School of Medicine, Zonguldak Bulent Ecevit University, Zonguldak, Turkey.

Background: The aim of this prospective, randomized, controlled study was to evaluate the analgesic effect of US-guided Pectoral (PECS) I blocks on postoperative analgesia after TIVAP insertion.

Methods: A hundred-twenty patients were included in this study. The patients were divided into two groups: Group PECS and Group INF (infiltration). Read More

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Closing the gap: evidence-based surgical treatment of rectus diastasis associated with abdominal wall hernias.

Hernia 2021 Jul 28. Epub 2021 Jul 28.

Department of Plastic and Reconstructive Surgery, Ohio State University Wexner Medical Center, 915 Olentangy River Road, Suite 2100, Columbus, OH, 43212, USA.

Purpose: Rectus diastasis (RD) associated with abdominal hernias present a surgical challenge associated with a paucity in treatment guidelines. The objective of this systematic review is to review surgical techniques and assess complication and recurrence rates of RD in patients with concurrent abdominal hernias.

Methods: PubMed and EMBASE databases were systematically searched, and data extraction was performed on articles which met the inclusion criteria. Read More

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Predictive Accuracy of Prenatal Ultrasound Findings for Lower Urinary Tract Obstruction: A systematic review and Bayesian meta-analysis.

Prenat Diagn 2021 Jul 27. Epub 2021 Jul 27.

Division of Urology, The Hospital for Sick Children (SickKids), Toronto, Ontario, Canada.

Lower urinary tract obstruction (LUTO) is a rare but critical fetal diagnosis. Different ultrasound markers have been reported with varying sensitivity and specificity. The objective of this systematic review and meta-analysis was to identify the diagnostic accuracy of ultrasound markers for LUTO. Read More

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Immunohistochemical study of inflammatory responses in septa arising from type I intestinal atresia.

Histol Histopathol 2021 Jul 27:18364. Epub 2021 Jul 27.

Department of Anatomy, Wuxi School of Medicine, Jiangnan University, WuXi, Jiangsu, PR China.

The purpose of this study was to evaluate defensive functional cells in intestinal septa during recanalization in the embryonic period, and to access immune responses in septa arising from type I intestinal atresia and normal intestinal walls. Tissue samples were of septa located in the intestinal wall at a distance <15cm from the ligament of Treitz, and normal intestine walls obtained from seven neonates who underwent surgery. Following serial tissue sectioning, the samples were subjected to hematoxylin and eosin (HE), periodic acid-Schiff (PAS) and immunohistochemical staining to determine the morphological features and markers of functional cells and immune responses in the septa and normal intestinal walls. Read More

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Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers.

J Am Heart Assoc 2021 Aug 27;10(15):e020227. Epub 2021 Jul 27.

Institute of Cardiovascular ScienceUniversity College London London UK.

Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments. We hypothesized that impaired MBF and myocardial perfusion reserve, quantified using perfusion mapping cardiac magnetic resonance, might occur in the absence of overt left ventricular hypertrophy (LVH) and late gadolinium enhancement, in mutation carriers without LVH criteria for HCM (genotype-positive, left ventricular hypertrophy-negative). Read More

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Dean migration of unfocused micron sized particles in low aspect ratio spiral microchannels.

Biomed Microdevices 2021 Jul 26;23(3):40. Epub 2021 Jul 26.

Department of Chemical & Biomolecular Engineering, National University of Singapore, Lower Kent Ridge Road, 117585, Singapore.

We present an analysis of the microfluidic Dean migration of 2.5 µm particles, which do not meet focus criterion, in tall and low aspect ratio microchannels. We demonstrate the use of such low aspect ratio and tall spirals (h > 50 µm) for isolating high concentration (> 10 particles or cells/mL) micron sized particles without an initial off-chip dilution step. Read More

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Differential Expression of Ki-67 and P27 in Cholesteatoma Compared to Skin Tissue Predicts the Prognosis of Adult Acquired Cholesteatoma.

J Int Adv Otol 2021 Jul;17(4):306-312

Department of Otorhinolaryngology, Mersin University School of Medicine, Mersin, Turkey.

Background: The aim of this study was to compare the differential Ki-67 and p27 staining properties of acquired cholesteatoma in adult patients for prognostic analysis.

Methods: Forty-two adult patients with acquired cholesteatoma were enrolled. The cholesteatoma and matched meatal skin tissues of the patients were immunostained with Ki-67 and p27 antibodies. Read More

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