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Prophylactic ligation of uterine arteries at its origin in laparoscopic surgical staging for endometrial cancer.

J Obstet Gynaecol Res 2021 Sep 27. Epub 2021 Sep 27.

Faculty of Medicine, Department of Obstetrics and Gynecology, Ondokuz Mayıs University, Samsun, Turkey.

Aim: The aim of this study was to compare the surgical outcomes between patients who were staged laparoscopically for early-stage endometrioid-type endometrial cancer (EC) between those who underwent prophylactic ligation of uterine arteries (UAs) prior to pelvic lymphadenectomy and the patients who were operated with standard procedure.

Methods: This retrospective study was conducted in women diagnosed with early-stage and low/intermediate-risk endometrioid-type EC. The control group included patients who underwent standard laparoscopic pelvic lymphadenectomy and the study group concerned patients who underwent prophylactic ligation of UA prior to pelvic lymphadenectomy. Read More

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September 2021

Rates of neuromuscular excitation during cycling in Parkinson's disease compared to healthy young and older adults.

Clin Biomech (Bristol, Avon) 2021 Sep 20;90:105488. Epub 2021 Sep 20.

University of Delaware, 547 College Ave, Newark, DE, USA. Electronic address:

Background: Bradykinesia affects mobility in some people with Parkinson's. Fall risk makes the neural control of maximal speed ambulatory movements difficult to study in Parkinson's. Stationary recumbent bicycling favors the use of electromyography at high movement speeds, and may better reveal neuromuscular rate limiters. Read More

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September 2021

Dissolved oxygen variation in the North China Plain river network region over 2011-2020 and the influencing factors.

Chemosphere 2021 Sep 23;287(Pt 3):132354. Epub 2021 Sep 23.

State Key Laboratory on Environmental Aquatic Chemistry, Research Center for Eco-Environmental Science, Chinese Academy of Science, P. O. Box 2871, Beijing, 100085, PR China.

The 2011-2020 data of dissolved oxygen (DO) and nutrients-total phosphorus (TP), solution reactive phosphorus (SRP), total nitrogen (TN), ammoniacal nitrogen (NH-N), and chemical oxygen demand (COD)-in the North China Plain river network region were analyzed. Moreover, the DO variation trend and the influencing factors were investigated. The results showed that between 2011 and 2020, the DO concentration steadily increased from <3 mg L to >5 mg L. Read More

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September 2021

Compatibility of six reduced-risk insecticides with Orius strigicollis (Heteroptera: Anthocoridae) predators for controlling Thrips hawaiiensis (Thysanoptera: Thripidae) pests.

Ecotoxicol Environ Saf 2021 Sep 24;226:112812. Epub 2021 Sep 24.

Fujian Key Laboratory for Monitoring and Integrated Management of Crop Pests, Institute of Plant Protection, Fujian Academy of Agricultural Sciences, Fuzhou 350013, PR China; Fuzhou Scientific Observing and Experimental Station of Crop Pests of Ministry of Agriculture and Rural Affairs, Fujian 350013, PR China. Electronic address:

Contact toxicity assessments of six reduced risk insecticides were carried out to compare their selectivity and sensitivity toward the minute pirate bug Orius strigicollis and its prey Thrips hawaiiensis. Additionally, and their potential exposure risk were evaluated for O. strigicollis. Read More

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September 2021

Measurement of the facial nerve thickness and its correlation with freezing phenomenon and hypomimia in Parkinson's disease.

Clin Neurol Neurosurg 2021 Sep 22;210:106960. Epub 2021 Sep 22.

Bozok University Medical School, Yozgat, Turkey. Electronic address:

Objective: Hypomimia is one of the diagnostic features in Parkinson's disease, and freezing blocks may also occur with the degenerative process. We investigated that the thickness of the cranial facial nerve that innervates facial expressions, and the relationship between bradymimia and freezing phenomena in these patients.

Methods: We included 70 patients and healthy participants in this cross-sectional study. Read More

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September 2021

Novel phantom for performance evaluation of contrast-enhanced 3D rotational angiography.

Phys Med 2021 Sep 24;90:91-98. Epub 2021 Sep 24.

Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok 16424, Indonesia.

Purpose: This technical note presents an in-house phantom with a specially designed contrast-object module constructed to address the need for three-dimensional rotational angiography (3DRA) testing.

Methods: The initial part of the study was a brief evaluation on the commercially available phantom used for 3DRA and computed tomography angiography (CTA) to confirm the need for a special phantom for 3D angiography. Once confirmed, an in-house phantom was constructed. Read More

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September 2021

Lumbar Disc Degeneration in Female Patients with and without Ovariectomy: A Case-control Study.

World Neurosurg 2021 Sep 24. Epub 2021 Sep 24.

Department of Spine Surgery, The Third Hospital of Hebei Medical University, No.139 Ziqiang Road, Shijiazhuang 050051, Hebei Province, P. R. China. Electronic address:

Objective: To provide clinical evidence on the potential influence of ovariectomy (OVX) on intervertebral disc degeneration (IVDD).

Methods: We retrospectively reviewed the patients with a history of OVX who visited our hospital for lower back pain. In addition, 60 age-matched patients without OVX were randomly selected as the control subjects. Read More

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September 2021

The Erector Spinae Plane Block in the Setting of Hip Arthroscopy: A prospective randomized controlled clinical trial.

Arthroscopy 2021 Sep 24. Epub 2021 Sep 24.

ARCUS Sportklinik Pforzheim, Germany.

Purpose: This study aimed to (1) investigate whether the use of an erector spinae plane block (ESPB) would reduce peri-operative pain after arthroscopic therapy for femoroacetabular impingement syndrome (FAIS) and (2) to examine the amount of adjunct (additional) opioids and post-operative nausea and vomiting (PONV).

Methods: Between October 2019 and October 2020, patients (N = 68) undergoing arthroscopic therapy for FAIS were randomly allocated into two groups. The first group received an ultrasound-guided (ESPB) block preoperatively with 30 ml of 0. Read More

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September 2021

Reductions in crop yields across China from elevated ozone.

Environ Pollut 2021 Sep 24:118218. Epub 2021 Sep 24.

The State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing, 100029, China; Centre for Excellence in Urban Atmospheric Environment, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China; College of Earth Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.

Exposure of crops to high concentrations of ozone can cause substantial reductions in yield that pose a serious threat to global food security. Here we provide comprehensive estimates of yield losses for key crops across China between 2014 and 2017 attributed to ozone using a number of new approaches. We use an air quality model at 5 km resolution and crop-specific dose-response functions developed for both concentration- and flux-based metrics. Read More

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September 2021

Lysis reagents, cell numbers, and calculation method influence high-throughput measurement of HDL-mediated cholesterol efflux capacity.

J Lipid Res 2021 Sep 24:100125. Epub 2021 Sep 24.

Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address:

HDL-mediated cholesterol efflux capacity (CEC) may protect against cardiovascular disease. However, CEC assays are not standardized, hampering their application in large cohorts and comparison between studies. To improve standardization, we systematically investigated technical differences between existing protocols that influence assay performance that have not been previously addressed. Read More

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September 2021

Effect of intracutaneous pyonex on analgesia and sedation in critically ill patients with mechanical ventilation.

Can J Physiol Pharmacol 2021 Sep 27. Epub 2021 Sep 27.

Affiliated Hospital of Nanjing University of Chinese Medicine, 375808, Nursing, No. 155, Hanzhong Road, Nanjing, Nanjing, China, 210028;

To evaluate the effect of intracutaneous pyonex on analgesia and sedation in critically ill patients who underwent mechanical ventilation. A total of 88 critically ill patients were divided into control group and intervention group. Critical-Care Pain Observation Tool (CPOT) and Richmond Agitation and Sedation Scale (RASS) were used to evaluate pain and agitation. Read More

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September 2021

Hypothermic Oxygenated Perfusion Ameliorates Ischemia-Reperfusion Injury of Fatty Liver in Mice via Brg1/Nrf2/HO-1 Axis.

Artif Organs 2021 Sep 27. Epub 2021 Sep 27.

Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Wuhan, China.

Background: After cold storage (CS) and subsequent transplantation, fatty liver is more inclined to develop liver dysfunction and serious postoperative complications in contrast to healthy liver. Hypothermic oxygenated perfusion (HOPE) is a safe and efficacious system, which can repair fatty liver and reduce ischemia-reperfusion injury. The aim of this research is to investigate the function of Brg1/Nrf2/HO-1 signaling pathway in the protective effect of HOPE on ischemia-reperfusion injury of fatty liver. Read More

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September 2021

Inequalities in Glycemic Control in Youth with Type 1 Diabetes Over Time: Intersectionality Between Socioeconomic Position and Race and Ethnicity.

Ann Behav Med 2021 Sep 27. Epub 2021 Sep 27.

Fred Hutchinson Cancer Research Center, University of Washington, and Seattle Children's Research Institute, Seattle, WA, USA.

Background: Racial/ethnic health inequities have been well-documented among youth and young adults with type 1 diabetes (T1D), yet little is known about how socioeconomic position (SEP) intersects with the risk marker of race/ethnicity to predict inequities in longitudinal glycemic control.

Purpose: To identify patterns of SEP, race/ethnicity, and clinical characteristics that differentiate hemoglobin A1c (HbA1c) trajectories among youth and young adults after T1D diagnosis.

Methods: The SEARCH for Diabetes in Youth cohort includes youth with diabetes diagnosed from 2002 to 2006 and 2008 who were followed through 2015. Read More

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September 2021

Low- and high-viscosity bulk-fill resin composites: a comparison of microhardness, microtensile bond strength, and fracture strength in restored molars.

Acta Odontol Latinoam 2021 Aug;34(2):173-182

Faculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Departamento de Odontologia Restauradora, Campinas, Brasil.

The aim of this study was to compare low- and high-viscosity bulk-fill composites for Knoop microhardness (KHN), microtensile bond strength (MTBS) to dentin in occlusal cavities, and fracture strength (FS) in molars with mesialocclusal- distal restoration. Disk-shaped samples with different thicknesses (2 or 4 mm) of low-viscosity (SDR Flow, Dentsply) and high-viscosity bulk-fill composites (Filtek BulkFill, 3M ESPE; and Tetric-N Ceram Bulk Fill, Ivoclar Vivadent) were prepared for top and bottom KHN analysis (n=10). MTBS to dentin and fracture pattern was evaluated in human molars with occlusal cavities restored with (n=10): conventional nanocomposite (Z350XT, 3M ESPE), low-viscosity (Filtek Bulk-fill Flow, 3M ESPE) or high-viscosity bulk-fill composites (Filtek BulkFill). Read More

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Hexavalent chromium exposure alters bone remodeling in the developing tooth alveolus and delays tooth eruption.

Acta Odontol Latinoam 2021 Aug;34(2):91-97

Universidad de Buenos Aires, Facultad de Odontología, Cátedra de Histología y Embriología, Buenos Aires, Argentina.

Although it has been demonstrated that exposure of lactating rats to CrVI delays tooth eruption, the effects of CrVI exposure on bone remodeling in the developing alveolus during tooth eruption remain unknown. Our purpose was to analyze the effect of CrVI in the alveolus of the first lower molar of rats. Thirty-two suckling Wistar rats were divided into two groups. Read More

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Predictors of social anxiety disorder with major depressive episodes among Japanese university students.

PLoS One 2021 27;16(9):e0257793. Epub 2021 Sep 27.

Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Background: Social anxiety disorder (SAD) develops in the early teens and is a common disorder among university students. Understanding the predictive factors of SAD comorbid with major depressive episode (MDE) is important for student mental health care. The aim of this study was to identify the personality traits that predict SAD with MDE by analyzing longitudinal data of Japanese university students. Read More

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September 2021

Body mass index in offspring of mothers with diabetes mellitus: follow-up at 2, 4, 6, and 8 years of age.

Bol Med Hosp Infant Mex 2021 ;78(5):395-403

Laboratorio de Neurofisiología Cognitiva, Instituto Nacional de Rehabilitación. Mexico City, Mexico.

Background: Offspring of mothers with diabetes mellitus (DM) during pregnancy may be at high risk for developmental alterations. This study aimed to identify the effects of maternal pre- and gestational diabetes on the body mass index of infants and children at two, four, six, and eight years of age.

Methods: We studied children of mothers with type 1, type 2, and gestational diabetes and a control group. Read More

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January 2021

Stroke és a cardiorespiratoricus fittség.

Authors:
Péter Apor

Orv Hetil 2021 Sep 26;162(39):1567-1572. Epub 2021 Sep 26.

1 Testnevelési Egyetem, Országos Sportegészségügyi Intézet, Budapest, Karolina út 27., 1113.

Összefoglaló. A fizikai inaktivitás a cardiovascularis betegségek - így a stroke - jelentős kockázati tényezője. A rendszeres testmozgás növeli az aerob kapacitást, a cardiorespiratoricus fittséget - ezzel csökkenti a cardiovascularis betegségek, köztük a stroke kockázatát. Read More

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September 2021

Intradermal methylene blue administration on the progression of burn injuries.

J Wound Care 2021 Sep;30(Sup9a):VIIIi-VIIIx

Department of Surgery, Ribeirao Preto School of Medicine, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil.

Objective: A burn injury has two defined areas: central necrosis and an adjacent area of ischaemia, which may or may not progress to necrosis. The concentration of nitric oxide (NO) increases after burn injury and may originate from potent oxidising agents. Methylene blue (MB) may act as an antioxidant and is supposed to reduce burn progression. Read More

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September 2021

Rationalizing the Design of Hyaluronic Acid-Decorated Liposomes for Targeting Epidermal Layers: A Combination of Molecular Dynamics and Experimental Evidence.

Mol Pharm 2021 Sep 27. Epub 2021 Sep 27.

Department of Pharmaceutical Sciences, Università degli Studi di Milano, via G. Colombo 71, 20133, Milan, Italy.

This work provides information on the features of low molecular weight hyaluronic acid (HA)-decorated liposomes to target resveratrol (RSV) in the skin. Deformable liposomes were made of soy-phosphatidylcholine with Tween 80 as the fluidizing agent. For HA conjugation, three different phosphoethanolamines were tested: 1,2-dipalmitoyl--glycero-3-phosphoethanolamine (DPPE), 1,2-dimyristoyl--glycero-3-phosphoethanolamine (DMPE), and 1,2-dioleoyl--glycero-3-phosphoethanolamine (DOPE). Read More

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September 2021

Hydrophilic Slippery Surface Promotes Efficient Defrosting.

Langmuir 2021 Sep 27. Epub 2021 Sep 27.

State Key Laboratory of Fine Chemicals, Institute of Chemical Engineering, Liaoning Key Laboratory of Clean Utilization of Chemical Resources, Dalian University of Technology, Dalian 116024, China.

Frost accretion occurs ubiquitously in various industrial applications and causes tremendous energy and economic loss, as manifested by the Texas power crisis that impacted millions of people over a vast area in 2021. To date, extensive efforts have been made on frost removal by micro-engineering surfaces with superhydrophobicity or lubricity. On such surfaces, air or oil cushions are introduced to suspend the frost layer and promote the rapid frost sliding off, which, although promising, faces the instability of the cushions under extreme frosting conditions. Read More

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September 2021

A pilot randomised controlled trial of befriending by volunteers in in people with intellectual disability and depressive symptoms.

J Intellect Disabil Res 2021 Sep 27. Epub 2021 Sep 27.

Epidemiology and Applied Clinical Research Department, Division of Psychiatry, University College London, London, UK.

Background: People with intellectual disability (ID) are more likely to experience chronic depression compared with the general population, which may be compounded by loneliness and lower levels of social support. Befriending aims to provide social support and promote engagement in community activities. No randomised controlled trials have examined whether befriending improves symptoms of depression and social outcomes in people with ID. Read More

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September 2021

Intravoxel Incoherent Motion Diffusion-Weighted Imaging for Predicting and Monitoring the Response of Anti-Angiogenic Treatment in the Orthotopic Nude Mouse Model of Lung Adenocarcinoma.

J Magn Reson Imaging 2021 Sep 27. Epub 2021 Sep 27.

Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Background: The treatment efficacy of angiogenesis inhibitor could be underestimated at an early stage based on tumor volume changes. Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) can quantitatively assess tumors at the cellular level, but it is unclear whether it can provide useful information for assessing treatment response of anti-angiogenic treatment for lung adenocarcinoma.

Purpose: To determine the use of IVIM-DWI for non-invasive monitoring of the early response to anti-angiogenic treatment in the orthotopic transplantation of lung adenocarcinoma model. Read More

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September 2021

Clinical and Demographic Factors Associated With Diabetic Retinopathy Among Young Patients With Diabetes.

JAMA Netw Open 2021 Sep 1;4(9):e2126126. Epub 2021 Sep 1.

Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison.

Importance: Diabetic retinopathy (DR) is a leading cause of vision loss worldwide. As the incidence of both type 1 and type 2 diabetes among youths continues to increase around the world, understanding the factors associated with the development of DR in this age group is important.

Objective: To identify factors associated with DR among children, adolescents, and young adults with type 1 or type 2 diabetes in the US. Read More

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September 2021

Trends in Chronic Kidney Disease Care in the US by Race and Ethnicity, 2012-2019.

JAMA Netw Open 2021 Sep 1;4(9):e2127014. Epub 2021 Sep 1.

Division of Nephrology, University of California, San Francisco.

Importance: Significant racial and ethnic disparities in chronic kidney disease (CKD) progression and outcomes are well documented, as is low use of guideline-recommended CKD care.

Objective: To examine guideline-recommended CKD care delivery by race and ethnicity in a large, diverse population.

Design, Setting, And Participants: In this serial cross-sectional study, adult patients with CKD that did not require dialysis, defined as a persistent estimated glomerular filtration rate less than 60 mL/min/1. Read More

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September 2021

Low- and high-viscosity bulk-fill resin composites: a comparison of microhardness, microtensile bond strength, and fracture strength in restored molars.

Acta Odontol Latinoam 2021 Aug;34(1):173-182

Faculdade São Leopoldo Mandic, Instituto de Pesquisas São Leopoldo Mandic, Departamento de Odontologia Restauradora, Campinas, Brasil.

The aim of this study was to compare low- and high-viscosity bulk-fill composites for Knoop microhardness (KHN), microtensile bond strength (MTBS) to dentin in occlusal cavities, and fracture strength (FS) in molars with mesialocclusal- distal restoration. Disk-shaped samples with different thicknesses (2 or 4 mm) of low-viscosity (SDR Flow, Dentsply) and high-viscosity bulk-fill composites (Filtek BulkFill, 3M ESPE; and Tetric-N Ceram Bulk Fill, Ivoclar Vivadent) were prepared for top and bottom KHN analysis (n=10). MTBS to dentin and fracture pattern was evaluated in human molars with occlusal cavities restored with (n=10): conventional nanocomposite (Z350XT, 3M ESPE), low-viscosity (Filtek Bulk-fill Flow, 3M ESPE) or high-viscosity bulk-fill composites (Filtek BulkFill). Read More

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Hexavalent chromium exposure alters bone remodeling in the developing tooth alveolus and delays tooth eruption.

Acta Odontol Latinoam 2021 Aug;34(1):91-97

Universidad de Buenos Aires, Facultad de Odontología, Cátedra de Histología y Embriología, Buenos Aires, Argentina.

Although it has been demonstrated that exposure of lactating rats to CrVI delays tooth eruption, the effects of CrVI exposure on bone remodeling in the developing alveolus during tooth eruption remain unknown. Our purpose was to analyze the effect of CrVI in the alveolus of the first lower molar of rats. Thirty-two suckling Wistar rats were divided into two groups. Read More

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Effectiveness of a Nurse-Led Web-Based Health Management in Preventing Women With Gestational Diabetes From Developing Metabolic Syndrome.

J Nurs Res 2021 Sep 23. Epub 2021 Sep 23.

PhD, RN, Assistant Professor, School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan, ROC MD, Associate Professor, Attending Physician, Department of Obstetrics and Gynecology, New Taipei Municipal TuCheng Hospital, New Taipei City, Taiwan, ROC MSN, RN, Supervisor, Department of Nursing, New Taipei Municipal TuCheng Hospital, and Adjunct Lecturer, Department of Nursing, Asia Eastern University of Science and Technology, New Taipei City, Taiwan, ROC MD, Associate Professor and Attending Physician, Department of Obstetrics and Gynecology, Linkou Chang Gung Memorial Hospital, Taoyuan City, Taiwan, ROC BSN, RN, Head Nurse, Department of Nursing, Linkou Chang Gung Memorial Hospital, Taoyuan City, Taiwan, ROC PhD, RN, Assistant Professor, Department of Nursing, Chang Gung University of Science and Technology, Taoyuan City, Taiwan, ROC.

Background: Women with gestational diabetes mellitus (GDM) are more likely to develop metabolic syndrome (MS). However, the effectiveness of web-based health management in preventing women at high risk of GDM from developing MS has rarely been studied.

Purpose: The aim of this study was to evaluate the longitudinal effects of nurse-led web-based health management on maternal anthropometric, metabolic measures, and neonatal outcomes. Read More

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September 2021

Pregnancy After Concussion: A Clarion Call for Attention?

J Head Trauma Rehabil 2021 Sep 23. Epub 2021 Sep 23.

Departments of Emergency Medicine (Dr Anto-Ocrah), Obstetrics and Gynecology (Drs Anto-Ocrah and Lewis), and Neurology (Dr Anto-Ocrah), School of Medicine and Dentistry, University of Rochester, Rochester, New York; and University of Rochester, Rochester, New York (Ms Cafferky).

Objective: Emerging research shows that women who sustain a mild traumatic brain injury, also termed concussion, have a higher risk of menstrual irregularities and sexual dysfunctions. However, no research exists on how these reproductive disruptions affect women's subsequent pregnancies. The objective of this study was to evaluate pregnancy outcomes after concussion in a cohort of reproductive-aged women (aged 18-45 years), 24 months post-injury. Read More

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September 2021

Carotid Arterial Compliance and Aerobic Exercise Training in Chronic Traumatic Brain Injury: A Pilot Study.

J Head Trauma Rehabil 2021 Sep 23. Epub 2021 Sep 23.

Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital, Dallas (Drs Tomoto, Tarumi, and Zhang); Departments of Neurology (Drs Tomoto, Le, Tarumi, Dieppa, Zhang, and Ding), Physical Medicine and Rehabilitation (Dr Bell), Neurological Surgery (Dr Madden), and Internal Medicine (Dr Zhang), University of Texas Southwestern Medical Center, Dallas; and Human Informatics Interaction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan (Dr Tarumi).

Objective: Decreased carotid arterial compliance (CAC) is associated with cerebral microvascular damage, cerebral blood flow (CBF) dysregulation, and increased risk for stroke and dementia, which are reported to be prevalent after traumatic brain injury (TBI). However, the effect of TBI on CAC has not been reported. The purposes of this pilot study were to (1) compare CAC between participants with chronic traumatic brain injury (cTBI) and age-matched healthy control (HC) subjects and (2) to examine whether CAC changed after 3 months of exercise training in those with cTBI. Read More

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September 2021