229,026 results match your criteria lower concentration


Mechanical Response of PEKK and PEEK As Frameworks for Implant-Supported Full-Arch Fixed Dental Prosthesis: 3D Finite Element Analysis.

Eur J Dent 2021 Sep 24. Epub 2021 Sep 24.

Department of Dentistry, University of Taubaté, Taubaté, São Paulo, Brazil.

Objective:  Polymeric framework represent an innovative approach for implant-supported dental prostheses. However, the mechanical response of ultra-high performance polymers as frameworks for full-arch prostheses under the "all-on-four concept" remains unclear. The present study applied finite element analysis to examine the behavior of polyetherketoneketone (PEKK) and polyetheretherketone (PEEK) prosthetic frameworks. Read More

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September 2021

HIV is Associated with Impaired Pulmonary Diffusing Capacity Independent of Emphysema.

J Acquir Immune Defic Syndr 2021 Sep 24. Epub 2021 Sep 24.

Johns Hopkins University School of Medicine, Baltimore, MD Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC.

Background: HIV is associated with accelerated decline in lung function and increased risk for Chronic Obstructive Pulmonary Disease (COPD). Recently there has been growing attention towards the impairment in the diffusing capacity of the lungs for carbon monoxide (DLCO), a marker of pulmonary gas exchange, observed among persons living with HIV. While increased emphysema can contribute to the DLCO impairment observed, other factors may drive this association. Read More

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September 2021

Poplar tree (Populus balsamifera L.) as indicator of mercury emission from a point source.

Chemosphere 2021 Sep 11;287(Pt 3):132157. Epub 2021 Sep 11.

National Research Tomsk Polytechnic University, Lenin Ave., 30, Tomsk, 634050, Russia.

The article provides original data on the ecological and geochemical characteristics of the distribution of Hg in the leaves and annual rings of balsam poplar (P. balsamifera L.) in the zone of influence of lithium production (Novosibirsk). Read More

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September 2021

Surfactant and dilatational viscosity effects on the deformation of liquid droplets in an electric field.

J Colloid Interface Sci 2021 Jul 21;607(Pt 1):900-911. Epub 2021 Jul 21.

Levich Institute and Department of Chemical Engineering, City College of the City University of New York, New York, NY 10031, USA.

Hypothesis: A conducting droplet suspended in an insulating continuous phase, e.g. an aqueous electrolyte in an oil, is deformed by an applied electric field to nonspherical equilibrium shapes, and can even break-up under strong fields. Read More

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Dose-dependent toxicological effects in rats following a 90-day dietary exposure to PCB-156 include retinoid disruption.

Reprod Toxicol 2021 Sep 21. Epub 2021 Sep 21.

Unit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

The toxicity of PCB-156 (2,3,3',4,4',5-hexachlorobiphenyl) was investigated in rats following subchronic dietary exposure. Groups of 10 male and female Sprague-Dawley rats were administered PCB-156 in the diet at 0, 0.01, 0. Read More

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September 2021

Physicochemical and biological evaluation of a triazine-methacrylate monomer into a dental resin.

J Dent 2021 Sep 21:103818. Epub 2021 Sep 21.

Department of Dental Materials, School of Dentistry, Federal University of Rio Grande do Sul. Ramiro Barcelos Street, 2492, Rio Branco, 90035-003, Porto Alegre, RS, Brazil. Electronic address:

Objectives: This study aimed to (1) formulate blend resins with 2.5 or 5 wt.% of the methacrylate monomer 1,3,5-triacryloylhexahydro-1,3,5-triazine (TAT), and (2) to evaluate the blend resins regarding the physicochemical and biological properties. Read More

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September 2021

Electroencephalographic evidence of unconscious and conscious attentional bias in people with functional gastrointestinal disorders: A pilot study.

Int J Psychophysiol 2021 Sep 21. Epub 2021 Sep 21.

Department of Psychology, Macquarie University, Sydney, Australia.

Debate continues as to whether an attentional bias towards threat displayed by sufferers of functional gastrointestinal disorders (FGIDs) is conscious and, thus, more amenable to change through psychological therapy. We compared the amplitudes of early (unconscious) and later (conscious) electroencephalographic (EEG) event-related potentials following silent reading of symptom-related, emotionally neutral, and emotionally negative nouns across two participant groups: 30 female FGID-sufferers who met diagnostic criteria for irritable bowel syndrome or functional dyspepsia, and 30 female healthy controls. Analogous indices based on alpha desynchronization were also examined, as were correlations between the EEG-based indices and a range of psychosocial variables. Read More

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September 2021

Development of a new peptide-bead coupling method for an all peptide-based Luminex multiplexing assay for detection of Plasmodium falciparum antibody responses.

J Immunol Methods 2021 Sep 21:113148. Epub 2021 Sep 21.

Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address:

Using a recombinant protein antigen for antibody testing shows a sum of antibody responses to multiple different immune epitopes existing in the protein antigen. In contrast, the antibody testing to an immunogenic peptide epitope reflects a singular antibody response to the individual peptide epitope. Therefore, using a panel of peptide epitopes provides an advantage for profiling multiple singular antibody responses with potential to estimate recent malaria exposure in human infections. Read More

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September 2021

Physical behavior of KR-12 peptide on solid surfaces and Langmuir-Blodgett lipid films: Complementary approaches to its antimicrobial mode against S. aureus.

Biochim Biophys Acta Biomembr 2021 Sep 21:183779. Epub 2021 Sep 21.

Materials Science Group, Institute of Chemistry, University of Antioquia, Calle 70 #52-21, AA 1226 Medellín, Colombia. Electronic address:

Biophysical characterization of antimicrobial peptides helps to understand the mechanistic aspects of their action. The physical behavior of the KR-12 antimicrobial peptide (e.g. Read More

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September 2021

Probing the Internal Dynamics and Shape of Simple Peptides in Urea, Guanidinium Hydrochloride, and Proline Solutions with Time-Resolved Fluorescence Anisotropy and Atomistic Cosolvent Simulations.

J Phys Chem B 2021 Sep 24. Epub 2021 Sep 24.

Department of Chemistry and Department of Molecular Biosciences, The University of Kansas, Lawrence, Kansas 66045, United States.

Picosecond time-resolved fluorescence anisotropy was used to measure the effect of denaturants and osmolytes on the reorientation dynamics of the simplest dipeptide. The solvent denaturants guanidinium hydrochloride (gdm), urea, and the osmolyte proline were used at several concentrations. Analysis of the concentration dependence of denaturants at a fixed temperature showed faster and slower reorientation time in two different denaturants at a nearly identical solvent viscosity (η). Read More

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September 2021

The MoveStrong program for promoting balance and functional strength training and adequate protein intake in pre-frail older adults: A pilot randomized controlled trial.

PLoS One 2021 24;16(9):e0257742. Epub 2021 Sep 24.

Department of Kinesiology and Health, University of Waterloo, Waterloo, ON, Canada.

Background: Balance and functional strength training can improve muscle strength and physical functioning outcomes and decrease the risk of falls in older adults. To maximize the benefits of strength training, adequate protein intake is also important. However, the number of older individuals that consume enough protein or routinely engage in strength training remains low at less than 5% and even lower for activities that challenge balance. Read More

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September 2021

Validity of the Alarm Point in Intraoperative Neurophysiological Monitoring of the Spinal Cord by the Monitoring Working Group of the Japanese Society for Spine Surgery and Related Research: A Prospective Multicenter Cohort Study of 1934 Cases.

Spine (Phila Pa 1976) 2021 Oct;46(20):E1069-E1076

Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.

Study Design: Prospective multicenter cohort study.

Objective: The aim of this study was to validate an alarm point of intraoperative neurophysiological monitoring () formulated by the Monitoring Working Group (WG) of the Japanese Society for Spine Surgery and Related Research (JSSR).

Summary Of Background Data: The Monitoring WG of the JSSR formulated an alarm point of IONM using transcranial electrical stimulation-muscle motor evoked potentials (Tc(E)-MEPs) and has conducted a prospective multicenter study. Read More

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October 2021

Acute Physical and Mental Activity Influence on Concussion Recovery.

Med Sci Sports Exerc 2021 Sep 17. Epub 2021 Sep 17.

Department of Kinesiology and Applied Physiology, Interdisciplinary program in Biomechanics and Movement Science University of Delaware, Newark, DE School of Health and Kinesiology, Georgia Southern University, Statesboro, GA Department of General Surgery, Orlando Health, Orlando, FL Department of Intercollegiate Athletics, Georgia Southern University, Statesboro, GA.

Introduction: Physical and mental activity post-concussion has received renewed attention to improve concussion management, however most protocols start after several days and do not assess the acute window. Therefore, the purpose of this study was to assess physical and mental activity in the first 48 hours post-concussion on the time to symptom free status and return to play.

Methods: We recruited 78 NCAA Division I athletes (Male: 51. Read More

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September 2021

The ages of zone of proximal development for retrospective time assessment and anticipation of time event.

Appl Neuropsychol Child 2021 Sep 24:1-10. Epub 2021 Sep 24.

Institute of Higher Nervous Activity and Neurophysiology, The Russian Academy of Science, Moscow, Russia.

From childhood to adulthood, an individual's ability to estimate and anticipate the timing of events changes continuously. This study investigated the ability of 287 children aged 5-14 years to estimate the duration of prior events and anticipate the timing of future events for determination of the age at which children improve their timing skills. The Luria neuropsychological assessment battery and the Wechsler Intelligence Scale for Children (WISC-IV) were applied to find correlations between timing skills and the development of cognitive functions. Read More

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September 2021

Antimicrobial activities of amphiphilic cationic polymers and their efficacy of combination with novobiocin.

J Biomater Sci Polym Ed 2021 Sep 24:1-14. Epub 2021 Sep 24.

Department of Materials Science and Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya, Japan.

Today, drug-resistant bacteria represent a significant problem worldwide. In fact, bacteria are becoming resistant even to newly developed antibiotics. Therefore, there is an urgent need to develop antibiotics to which bacteria cannot become resistant. Read More

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September 2021

Biomechanical evaluation of 3-unit fixed partial dentures on monotype and two-piece zirconia dental implants.

Comput Methods Biomech Biomed Engin 2021 Sep 24:1-8. Epub 2021 Sep 24.

Department of Dental Materials and Prosthodontics, Institute of Science and Technology, São Paulo State University (UNESP), Sao Paulo, Brazil.

This study aimed to evaluate the biomechanical behavior, stress distributions and bone microstrain of fixed partial dentures (FPD) with ceramic abutments supported on monotype zirconia implants, titanium implants and two-piece zirconia implants, using finite element analysis. A three-dimensional model of the jaw was simulated containing 1.0 mm thick cortical bone and cancellous bone tissue. Read More

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September 2021

Clinical features of Chinese children with COVID-19 and other viral respiratory infections.

Pediatr Pulmonol 2021 Sep 24. Epub 2021 Sep 24.

Department of Infectious Diseases, National Clinical Research Center for Child Health and Disorders,The Children's Hospital of Chongqing Medical University, Chongqing, China.

Objective: Few studies have explored the clinical features in children infected with SARS-CoV-2 and other common respiratory viruses, including respiratory syncytial virus (RSV), influenza virus (IV), and adenovirus (ADV). Herein, we reported the clinical characteristics and cytokine profiling in children with COVID-19 or other acute respiratory tract infections (ARTI).

Methods: We enrolled 20 hospitalized children confirmed as COVID-19 positive, 58 patients with ARTI, and 20 age and sex-matched healthy children. Read More

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September 2021

Probability of survival and stress distribution of narrow diameter implants with different implant-abutment taper angles.

J Biomed Mater Res B Appl Biomater 2021 Sep 24. Epub 2021 Sep 24.

Department of Prosthodontics and Periodontology, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.

This study evaluated the probability of survival, failure mode, and stress distribution of narrow diameter implants (NDIs) with internal implant-abutment conical connection comprised of different taper angles and thread designs. Sixty-three NDIs (Ø 3.5 × 8. Read More

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September 2021

Population pharmacokinetics of subcutaneous infliximab CT-P13 in Crohn's disease and ulcerative colitis.

Aliment Pharmacol Ther 2021 Sep 24. Epub 2021 Sep 24.

Department of Hospital Pharmacy - Clinical Pharmacology, Amsterdam UMC, Amsterdam, the Netherlands.

Background: Infliximab is a chimeric monoclonal antibody against tumour necrosis factor-alpha for the treatment of Crohn's disease (CD) and ulcerative colitis (UC). Recently, a subcutaneous formulation of CT-P13, an infliximab biosimilar, was approved for clinical use.

Aims: To characterise CT-P13 pharmacokinetics (PK) and its clinically relevant determinants after subcutaneous administration through population PK modelling. Read More

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September 2021

Management of phosphorus nutrient amidst climate change for sustainable agriculture.

J Environ Qual 2021 Sep 24. Epub 2021 Sep 24.

Xavier Research Foundation, St. Xavier's College, Palayamkottai, Tamil Nadu, 620002, India.

Nutrients are essential for plant growth and development; they influence the overall agricultural production. Phosphorus (P) is a major nutrient required for many physiological and biochemical functions of the plant. Phosphate rock is the major source of phosphate fertilizer which is becoming increasingly limited in both developing and developed countries. Read More

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September 2021

Cyclosporine A C monitoring reflects the area under the curve in children with nephrotic syndrome: a single-center experience.

Clin Exp Nephrol 2021 Sep 24. Epub 2021 Sep 24.

Department of Pediatrics, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo, 173-8605, Japan.

Background: The currently used single-monitoring method for drug-blood-level evaluation in cyclosporine A (CsA) treatment for nephrotic syndrome (NS) was established through hourly measurements based on adult organ transplantation. However, the pharmacokinetics may differ due to different concomitant medications, age, and conditions. This study was conducted to determine the measurement timing that best reflects the CsA area under the curve (AUC) in pediatric NS. Read More

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September 2021

The influence of edema on the bisoprolol blood concentration after bisoprolol dermal patch application: A case-control study.

Medicine (Baltimore) 2021 Sep;100(38):e27354

Department of Emergency and Critical Care Medicine, Hitachi General Hospital, 2-1-1, Jonan-cho, Hitachi, Ibaraki, Japan.

Background: Beta-blocking is important for critically ill patients. Although some patients are required to continue taking beta-blockers after they no longer need critical care, some of these patients have impaired swallowing abilities. Bisoprolol dermal patches have recently been introduced and appear to be a good alternative to oral bisoprolol tablets. Read More

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September 2021

Impact of light on anoxic/oxic reactors: performance, quorum sensing, and metagenomic characteristics.

Water Sci Technol 2021 Sep;84(6):1452-1463

School of Environmental and Municipal Engineering, Tianjin Chengjian University, Tianjin 300384, China.

The effect of light has raised attention on wastewater treatment. However, little research has concentrated on the influences of light on activated sludge. In this study, the influences of light on the performance, quorum sensing (QS) and metagenomic characteristics of anoxic/oxic reactors were investigated. Read More

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September 2021

The Role of Interpersonal Relationships and Household Socioeconomic Status in the Association Between Sexual Orientation and Health: A Moderated Mediation Analysis.

LGBT Health 2021 Sep 24. Epub 2021 Sep 24.

Vanke School of Public Health, Tsinghua University, Beijing, P.R. China.

Emerging studies indicate that sexual minority youths experience worse health than their heterosexual peers, but few studies have examined the intervening mechanisms linking sexual orientation and health status. This study hypothesizes that interpersonal relationships, moderated by household socioeconomic status (HSES), are important mediators in the association between sexual orientation and health status. A total of 49,084 youths, consisting of 9499 youths who identified as sexual minority individuals and 39,585 youths who identified as heterosexual, were sampled from a national study on sexual and reproductive health conducted in China. Read More

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September 2021

Correlations between hippocampal functional connectivity, structural changes, and clinical data in patients with relapsing-remitting multiple sclerosis: a case-control study using multimodal magnetic resonance imaging.

Neural Regen Res 2022 May;17(5):1115-1124

First Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.

Multiple sclerosis is associated with structural and functional brain alterations leading to cognitive impairments across multiple domains including attention, memory, and the speed of information processing. The hippocampus, which is a brain important structure involved in memory, undergoes microstructural changes in the early stage of multiple sclerosis. In this study, we analyzed hippocampal function and structure in patients with relapsing-remitting multiple sclerosis and explored correlations between the functional connectivity of the hippocampus to the whole brain, changes in local brain function and microstructure, and cognitive function at rest. Read More

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Vancomycin and daptomycin stability in heparin or sodium citrate lock solutions.

J Vasc Access 2021 Sep 24:11297298211045893. Epub 2021 Sep 24.

Nephrology Service, Hospital General Universitario de Castellón, Castellón de la Plana, Spain.

Background: We investigated physical and chemical stability of daptomycin and vancomycin in heparin or sodium citrate lock solutions. The aim of this study was to find the optimal combination of antimicrobials and additives for lock solutions, which maximized patient safety.

Methods: Vancomycin and daptomycin were diluted with heparin or sodium citrate to achieve final concentrations of vancomycin-heparin 2. Read More

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September 2021

Concentration of LDLR, degree of hepatic fibrosis and hepatic steatosis in patients with chronic hepatitis B infection treated with tenofovir disoproxil fumarate.

Ann Agric Environ Med 2021 Sep 10;28(3):458-462. Epub 2020 Jun 10.

Medical University, Lublin, Poland.

Introduction: Epidemiological data indicate that one-third of the world's population have serological markers of hepatitis B virus infection. Hepatic steatosis is often observed in patients with chronic liver diseases. The exact mechanisms of hepatic steatosis progression and the efficacy of antiviral therapy in patients with CHB and hepatic steatosis are not yet fully understood. Read More

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September 2021

Correlation between vitamin D and alterations in MRI among patients with multiple sclerosis.

Ann Agric Environ Med 2021 Sep 17;28(3):372-377. Epub 2020 Sep 17.

Department of Neurology, Medical University, Lublin, Poland.

Introduction: Multiple sclerosis (MS) is a disease of unknown etiology. Diagnosis of MS is primarily based on detection of myelin damage by magnetic resonance imaging (MRI) and classification of demyelination according to the McDonald Criteria. Cholecalciferol (vitamin D) has been shown to affect the onset and progression of MS via its immunomodulating properties. Read More

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September 2021

Outcomes of pregnant broodmares treated for colic at a tertiary care facility.

Vet Surg 2021 Sep 23. Epub 2021 Sep 23.

Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, Pennsylvania, USA.

Objective: To evaluate, following colic admission during pregnancy, (1) broodmare survival; (2) the frequency of recurrent colic in broodmares and its associated variables, and (3) pregnancy outcome and the variables associated with a negative pregnancy outcome.

Study Design: Ambidirectional observational cohort study.

Animals: One hundred and four client-owned broodmare admissions. Read More

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September 2021

Concentration, Source, and Health Risk of Trace Metals in Some Liquid Herbal Medicine Sold in Nigeria.

Biol Trace Elem Res 2021 Sep 24. Epub 2021 Sep 24.

Department of Community Medicine, Faculty of Clinical Sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.

The ingestion of toxic metals through liquid herbal medicine over a long period of time, and in excessive dose, may result in chronic accumulation that could cause disorder to several organs of the body. This study evaluated the concentration, source, and probable health risk of 8 trace metals in liquid herbal medicines sold in Nigeria. Triplicate samples of 10 different brands of liquid herbal formulations were analyzed using flame atomic absorption spectrophotometer. Read More

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September 2021