1,491 results match your criteria looming

Unequal distribution of COVID-19 vaccine: A looming crisis.

J Med Virol 2021 May 3. Epub 2021 May 3.

School of Pharmacy, Monash University, Subang Jaya, Selangor, Malaysia.

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Orthodontic space closure in a young female patient with solitary median maxillary central incisor syndrome.

Am J Orthod Dentofacial Orthop 2021 Apr 30. Epub 2021 Apr 30.

Private Practice, Bolzano and University of Ferrara, Ferrara, Italy.

A solitary median maxillary incisor can occur as a rare single dental anomaly or a symptom of the early-intrauterine developmental brain disorder of holoprosencephaly. The few published case reports about orthodontic treatment for this disorder have only described space opening for prosthodontic replacement of a central incisor. In contrast, the present patient was treated with extraction of the solitary median maxillary central incisor and orthodontic space closure with subsequent minimally invasive restorations in order to avoid looming esthetic or periodontal sequelae associated with any type of fixed bridgework or implant-borne crowns in the sensitive maxillary anterior area-which is especially indicated in young girls with a hyperdivergent growth pattern. Read More

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Climate change during the COVID-19 outbreak: scoping future perspectives.

Environ Sci Pollut Res Int 2021 May 2. Epub 2021 May 2.

Department of Economics and Business Administration, Art & Social Sciences Division, University of Education Lahore (Faisalabad Campus), Faisalabad, Pakistan.

Neither war nor recession or any kind of prior disaster has been considered a prelude to the looming threat of climate change over the past era as coronavirus (hereafter COVID-19) has in only a few months. Although numerous studies have already been published on this topic, there has not been compelling evidence critically assessing the impact of COVID-19 by and on climate change. The present study fills this gap by taking a more holistic approach to elaborate factors, e. Read More

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A Shortage of Neurologists We Must Act Now: A Report From the AAN 2019 Transforming Leaders Program.

Neurology 2021 Apr 30. Epub 2021 Apr 30.

Jennifer Juhl Majersik, Department of Neurology, Division of Vascular Neurology, University of Utah, Salt Lake City, UT; Aiesha Ahmed, MD, MBA, Departments of Neurology and Medicine, Penn State Health, Hershey, PA; I-Hweii Amy Chen, MD, PhD, Department of Neurology, Division of Neuromuscular Medicine, Medical University of South Carolina, Charleston, SC; Holly Shill, MD, Barrow Neurological Institute, University of Arizona College of Medicine-Phoenix, Phoenix, AZ; Gregory Hanes, MD, Sarasota Memorial Hospital, Sarasota, FL; Victoria Pelak, MD, Departments of Neurology and Ophthalmology, University of Colorado School of Medicine, Aurora, CO; Jennifer Lynn Hopp, MD, Department of Neurology, University of Maryland School of Medicine, Baltimore, MD; Antonio Omuro, MD, Department of Neurology, Yale School of Medicine, New Haven, CT; Benzi Kluger, MD, MS, Departments of Neurology and Medicine, University of Rochester Medical Center, Rochester, NY; Thabele Leslie-Mazwi, Departments of Neurosurgery and Neurology, Massachusetts General Hospital, Boston, MA.

In nearly every US state today, a large mismatch exists between the need for neurologists and neurological services and the availability of neurologists to provide these services. Patients with neurologic disorders are rising in prevalence and require access to high level care to reduce disability. The current neurology mismatch reduces access to care, worsens patient outcomes, and erodes career satisfaction and quality of life for neurologists as they face increasingly insurmountable demands. Read More

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Male courtship song drives escape responses that are suppressed for successful mating.

Sci Rep 2021 Apr 29;11(1):9227. Epub 2021 Apr 29.

Champalimaud Research, Champalimaud Center for the Unknown, 1400-038, Lisbon, Portugal.

Persuasion is a crucial component of the courtship ritual needed to overcome contact aversion. In fruit flies, it is well established that the male courtship song prompts receptivity in female flies, in part by causing sexually mature females to slow down and pause, allowing copulation. Whether the above receptivity behaviours require the suppression of contact avoidance or escape remains unknown. Read More

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Coronavirus Disease 19 and Future Ecological Crises: Hopes from Epigenomics and Unraveling Genome Regulation in Humans and Infectious Agents.

Kevin Dzobo

OMICS 2021 Apr 27. Epub 2021 Apr 27.

International Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town Component, Cape Town, South Africa.

With coronavirus disease 19 (COVID-19), we have witnessed a shift from public health to planetary health and a growing recognition of the importance of systems science in developing effective solutions against pandemics in the 21st century. COVID-19 and the history of frequent infectious outbreaks in the last two decades suggest that COVID-19 is likely a dry run for future ecological crises. Now is the right time to plan ahead and deploy the armamentarium of systems science scholarship for planetary health. Read More

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Factors That Affect Drivers' Perception of Closing and an Immediate Hazard.

Hum Factors 2021 Apr 19:187208211009028. Epub 2021 Apr 19.

576471 Rimkus Consulting Group, Inc., Houston, Texas, USA.

Objective: To measure the looming threshold for when drivers perceive closing and an immediate hazard and determine what factors affect these thresholds.

Background: Rear-end collisions are a common type of crash. One key issue is determining when drivers first perceive they need to react. Read More

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Bacteriophage therapy for challenging bacterial infections: achievements, limitations and prospects for future clinical use by veterinary dermatologists.

Vet Dermatol 2021 Apr 18. Epub 2021 Apr 18.

Discipline of Veterinary Science, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, 4814, Australia.

Background: Bacteriophages were discovered just over 100 years ago and have been used to treat bacterial infections in animals since the 1920s. The antimicrobial resistance crisis has led to a new surge of interest in the use of bacteriophage therapy as an alternative or supplement to antimicrobial therapy in humans and other animals.

Objectives: To describe the nature of bacteriophages and provide a critical review and update on the clinical use of bacteriophages in the treatment of challenging bacterial infections, with an emphasis on companion animal veterinary applications. Read More

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Leadership for a climate resilient, net-zero health system: Transforming supply chains to the circular economy.

Neil H Ritchie

Healthc Manage Forum 2021 Apr 15:8404704211003610. Epub 2021 Apr 15.

482659Canadian Coalition for Green Health Care, Halifax, Nova Scotia, Canada.

The global pandemic has taught us that we can focus the attention of the healthcare system on a clear intention when there is a looming threat. Climate action is required from multiple stakeholders particularly private sector suppliers in order to achieve the net-zero carbon emission by 2050 goal established by the Canadian government. Also building climate resilience among healthcare institutions and their supply chains is urgently needed, as they are already affected by a changing climate. Read More

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GABAergic retinal ganglion cells regulate innate defensive responses.

Neuroreport 2021 May;32(7):643-649

Eye Center, Renmin Hospital of Wuhan University, Wuhan University, Wuhan, Hubei.

Gamma-aminobutyric acid (GABA) is regarded as the most important inhibitory neurotransmitter in the central nervous system, including the retina. However, the roles of GABA-immunolabeled retinal ganglion cells (RGCs) have not been explored. Here, we report the expression of GABAergic RGCs that project to many brain areas in mice, including the superior colliculus. Read More

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The disturbance leg-lift response (DLR): an undescribed behavior in bumble bees.

PeerJ 2021 25;9:e10997. Epub 2021 Mar 25.

Department of Psychology, Converse College, Spartanburg, SC, United States of America.

Background: Bumble bees, primarily and , are becoming increasingly popular organisms in behavioral ecology and comparative psychology research. Despite growing use in foraging and appetitive conditioning experiments, little attention has been given to innate antipredator responses and their ability to be altered by experience. In this paper, we discuss a primarily undescribed behavior, the disturbance leg-lift response (DLR). Read More

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The Looming Effects of Estrogen in Covid-19: A Rocky Rollout.

Front Nutr 2021 18;8:649128. Epub 2021 Mar 18.

Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.

In the face of the Covid-19 pandemic, an intensive number of studies have been performed to understand in a deeper way the mechanisms behind better or worse clinical outcomes. Epidemiologically, men subjects are more prone to severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) infections than women, with a similar scenario being also stated to the previous coronavirus diseases, namely, SARS-CoV in 2003 and Middle East Respiratory Syndrome coronavirus diseases (MERS-CoV) in 2012. In addition, and despite that aging is regarded as an independent risk factor for the severe form of the disease, even so, women protection is evident. Read More

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Projections of the Impact to Arthroplasty Surgeons With Changes to the 2021 Medicare Physician Fee Schedule-A Looming Crisis of Access to Care?

J Arthroplasty 2021 Mar 11. Epub 2021 Mar 11.

Rothman Orthopaedic Institute, Thomas Jefferson University Hospital, Philadelphia, PA.

Background: The Centers for Medicare and Medicaid Services 2021 Physician Fee Schedule (PFS) includes increases in office reimbursement but decreases in the valuation of total hip arthroplasty and total knee arthroplasty and the conversion factor. The purpose of this study was to determine the financial impact of these changes on arthroplasty surgeons.

Methods: We queried data for 35 arthroplasty surgeons within our practice from 10/2019 to 10/2020 and captured all office and arthroplasty-related surgical procedure codes. Read More

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OFF-transient alpha RGCs mediate looming triggered innate defensive response.

Curr Biol 2021 Mar 29. Epub 2021 Mar 29.

Institute of Neuroscience, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China. Electronic address:

Animals respond to visual threats, such as a looming object, with innate defensive behaviors. Here, we report that a specific type of retinal ganglion cell (RGC), the OFF-transient alpha RGC, is critical for the detection of looming objects. We identified Kcnip2 as its molecular marker. Read More

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COVID-19 and Preparing Planetary Health for Future Ecological Crises: Hopes from Glycomics for Vaccine Innovation.

OMICS 2021 04 31;25(4):234-241. Epub 2021 Mar 31.

School of Medical and Health Sciences, Edith Cowan University, Perth, Australia.

A key lesson emerging from COVID-19 is that pandemic proofing planetary health against future ecological crises calls for systems science and preventive medicine innovations. With greater proximity of the human and animal natural habitats in the 21st century, it is also noteworthy that zoonotic infections such as COVID-19 that jump from animals to humans are increasingly plausible in the coming decades. In this context, glycomics technologies and the third alphabet of life, the sugar code, offer veritable prospects to move omics systems science from discovery to diverse applications of relevance to global public health and preventive medicine. Read More

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The Strategy of Predator Evasion in Response to a Visual Looming Stimulus in Zebrafish ().

A McKee M J McHenry

Integr Org Biol 2020 10;2(1):obaa023. Epub 2020 Aug 10.

Department of Ecology and Evolutionary Biology, University of California, 321 Steinhaus Hall, Irvine, CA 92697, Irvine.

A diversity of animals survive encounters with predators by escaping from a looming visual stimulus. Despite the importance of this behavior, it is generally unclear how visual cues facilitate a prey's survival from predation. Therefore, the aim of this study was to understand how the visual angle subtended on the eye of the prey by the predator affects the distance of adult zebrafish () from predators. Read More

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An Infrared Touch System for Automatic Behavior Monitoring.

Neurosci Bull 2021 Mar 31. Epub 2021 Mar 31.

Shenzhen Key Laboratory of Neuropsychiatric Modulation and Collaborative Innovation Center for Brain Science, Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Center for Excellence in Brain Science and Intelligence Technology, the Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.

Key requirements of successful animal behavior research in the laboratory are robustness, objectivity, and high throughput, which apply to both the recording and analysis of behavior. Many automatic methods of monitoring animal behavior meet these requirements. However, they usually depend on high-performing hardware and sophisticated software, which may be expensive. Read More

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Slow Resting State Fluctuations Enhance Neuronal and Behavioral Responses to Looming Sounds.

Brain Topogr 2021 Mar 25. Epub 2021 Mar 25.

Royal's Institute of Mental Health Research, University of Ottawa, 1145 Carling Avenue, Ottawa, ON, K1Z 7K4, Canada.

We investigate both experimentally and using a computational model how the power of the electroencephalogram (EEG) recorded in human subjects tracks the presentation of sounds with acoustic intensities that increase exponentially (looming) or remain constant (flat). We focus on the link between this EEG tracking response, behavioral reaction times and the time scale of fluctuations in the resting state, which show considerable inter-subject variability. Looming sounds are shown to generally elicit a sustained power increase in the alpha and beta frequency bands. Read More

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Effects of cognitive load and type of object on the visual looming bias.

Atten Percept Psychophys 2021 May 9;83(4):1508-1517. Epub 2021 Mar 9.

Department of Psychology, University of Kansas, Lawrence, KS, USA.

According to the behavioral urgency hypothesis, organisms have evolved various mechanisms that facilitate their survival by focusing attention and resources on approaching danger. One example of such mechanisms is the looming bias-the tendency for an individual to judge an approaching object's distance as being closer or time-to-collision as being sooner than receding or stationary objects. To date, most research on the looming bias has explored the ways in which human factors and object characteristics influence the strength and direction of the bias. Read More

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What is the Effect of Stimulus Complexity on Attention to Repeating and Changing Information in Autism?

J Autism Dev Disord 2021 Mar 19. Epub 2021 Mar 19.

Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Institute of Mental Health, Innovation Park, Triumph Road, Nottingham, NG7 2TU, United Kingdom.

Slower habituation to repeating stimuli characterises Autism, but it is not known whether this is driven by difficulties with information processing or an attentional bias towards sameness. We conducted eye-tracking and presented looming geometrical shapes, clocks with moving arms and smiling faces, as two separate streams of stimuli (one repeating and one changing), to 7-15 years old children and adolescents (n = 103) with Autism, ADHD or co-occurring Autism+ADHD, and neurotypical children (Study-1); and to neurotypical children (n = 64) with varying levels of autistic traits (Study-2). Across both studies, autistic features were associated with longer looks to the repeating stimulus, and shorter looks to the changing stimulus, but only for more complex stimuli, indicating greater difficulty in processing complex or unpredictable information. Read More

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COVID-19: Is herd immunity the only option for fragile Yemen?

Int J Infect Dis 2021 Mar 15;106:79-82. Epub 2021 Mar 15.

School of Social Sciences, Main Campus, University Sains Malaysia, Penang, Malaysia.

The first case of COVID-19 in Yemen was confirmed on 10 April 2020. Having faced with a six-year long conflict that has destroyed half of its healthcare facilities and displaced millions, predictions of infections and mortality in Yemen suggested a looming healthcare catastrophe. Difficulty in implementing coordinated lockdowns and preventive measures due to the daily labor working nature of the majority of the population, provided the perfect breeding ground for the SARS-CoV-2 virus. Read More

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Assessment of aquifer vulnerability using a developed "GODL" method (modified GOD model) in a schist belt environ, Southwestern Nigeria.

Environ Monit Assess 2021 Mar 17;193(4):199. Epub 2021 Mar 17.

Department of Applied Geophysics, Federal University of Technology, Akure, Nigeria.

Developing a predictive decision model for assessing the vulnerability of hidden groundwater reservoir formation to contamination risk via unavoidable anthropogenic activities is a key to managing water resources looming security crisis globally. This study explored multiple and robust methodologies including GIS, analytical hierarchy process (AHP)-based data mining, statistical and geophysical techniques for developing a novel "GODL" vulnerability method: a modified GOD model to ameliorate these challenges. The input for the modeling was based on the 65 located depth sounding geophysical data occupied in a schist belt environ, Southwestern Nigeria. Read More

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Microglial trogocytosis and the complement system regulate axonal pruning in vivo.

Elife 2021 03 16;10. Epub 2021 Mar 16.

Department of Neurology & Neurosurgery, Montreal Neurological Institute-Hospital, McGill University, Montreal, Canada.

Partial phagocytosis-called trogocytosis-of axons by microglia has been documented in ex vivo preparations but has not been directly observed in vivo. The mechanisms that modulate microglial trogocytosis of axons and its function in neural circuit development remain poorly understood. Here, we directly observe axon trogocytosis by microglia in vivo in the developing retinotectal circuit. Read More

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Fearful faces modulate spatial processing in peripersonal space: An ERP study.

Neuropsychologia 2021 Jun 17;156:107827. Epub 2021 Mar 17.

Centro studi e ricerche in Neuroscienze Cognitive, Dipartimento di Psicologia, Alma Mater Studiorum - Università di Bologna, Campus di Cesena, 47521, Cesena, Italy.

Peripersonal space (PPS) represents the region of space surrounding the body. A pivotal function of PPS is to coordinate defensive responses to threat. We have previously shown that a centrally-presented, looming fearful face, signalling a potential threat in one's surroundings, modulates spatial processing by promoting a redirection of sensory resources away from the face towards the periphery, where the threat may be expected - but only when the face is presented in near, rather than far space. Read More

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E-cigarettes: A novel therapy or a looming catastrophe.

Ann Thorac Med 2021 Jan-Mar;16(1):73-80. Epub 2021 Jan 14.

Department of Pulmonary/Critical Care and Sleep Medicine, Virginia Tech Carilion School of Medicine, Roanoke, VA, USA.

Electronic cigarettes (e-cigarettes) were originally developed in 2003 as healthier alternatives to conventional tobacco cigarettes. Their popularity has since significantly increased and both users and nonusers are exposed to their aerosol and product constituents. Although some evidence suggests that e-cigarette use may facilitate smoking cessation, definitive data are lacking and e-cigarettes are not approved by the Food and Drug Administration as a cessation aid. Read More

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January 2021

Stable and Novel Quantitative Trait Loci (QTL) Confer Narrow Root Cone Angle in an Aerobic Rice (Oryza sativa L.) Production System.

Rice (N Y) 2021 Mar 7;14(1):28. Epub 2021 Mar 7.

The University of Queensland, School of Agriculture and Food Sciences, Brisbane, QLD, 4072, Australia.

Background: Aerobic rice production (AP) may be a solution to the looming water crisis by utilising less water compared to traditional flooded culture. As such, development of genotypes with narrow root cone angle (RCA) is considered a key AP adaptation trait as it could lead to deeper rooting and ensure water uptake at depth. Quantitative trait loci (QTL) and genes associated with rooting angle have been identified in rice, but usually in conventional transplanted systems or in upland and drought conditions. Read More

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Rapid Methods for Antimicrobial Resistance Diagnostics.

Antibiotics (Basel) 2021 Feb 20;10(2). Epub 2021 Feb 20.

Department of Food Hygiene and Technology, University of León, 24071 León, Spain.

Antimicrobial resistance (AMR) is one of the most challenging threats in public health; thus, there is a growing demand for methods and technologies that enable rapid antimicrobial susceptibility testing (AST). The conventional methods and technologies addressing AMR diagnostics and AST employed in clinical microbiology are tedious, with high turnaround times (TAT), and are usually expensive. As a result, empirical antimicrobial therapies are prescribed leading to AMR spread, which in turn causes higher mortality rates and increased healthcare costs. Read More

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February 2021

Addressing Kentucky's Physician Shortage While Securing a Network for a Research-Intensive, Referral Academic Medical Center: Where Public Policy Meets Effective Clinical Strategic Planning.

Acad Med 2021 03;96(3):375-380

M. Karpf is advisor to the president and professor of internal medicine, University of Kentucky, Lexington, Kentucky.

A critical shortage of physicians is looming in the United States. The situation in Kentucky is especially dire, especially in rural areas. Class size constraints have resulted in the University of Kentucky College of Medicine (UK COM) unable to admit over 100 qualified Kentuckians each year. Read More

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Visual-looming Shadow Task with Calcium Activity Monitoring to Assess Defensive Behaviors in Mice.

Bio Protoc 2020 Nov 20;10(22):e3826. Epub 2020 Nov 20.

Hotchkiss Brain Institute & Department of Physiology & Pharmacology, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.

There has been a clear movement in recent years towards the adoption of more naturalistic experimental regimes for the study of behavior and its underlying neural architecture. Here we provide a protocol that allows experimenters working with mice, to mimic a looming and advancing predatory threat from the sky. This approach is easy to implement and can be combined with sophisticated neural recordings that allow access to real-time activity during behavior. Read More

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November 2020

Nursing Professionals' Stress Level During COVID-19: A Looming Workforce Issue.

J Nurse Pract 2021 Feb 23. Epub 2021 Feb 23.

Assistant Professor, FNP Coordinator, Brenau University, Gainesville, GA.

Objectives: The purpose of this study was to assess the impact of COVID-19 on perceived stress experienced by nurse practitioners/nurses and their desire to remain employed as healthcare providers.

Methods: Cross-sectional survey of 40 questions was administered between May and September 2020 to a convenience sample of 433 nurse practitioners and nurses in Missouri and Georgia through a Qualtrics link provided via their professional organization list-serv.

Results: Anxiety-related symptoms and perceived helplessness were correlated with PPE concerns and management approachability. Read More

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February 2021