987 results match your criteria lonicera sanghuangporus

Two new chemical constituents from .

Nat Prod Res 2021 May 7:1-7. Epub 2021 May 7.

Jiangsu Kanion Pharmaceutical Co. Ltd, and State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Jiangsu, Lianyungang, China.

Two new chemical constituents, japopenoid D (), and japopenoid E (), were isolated and identified from the flower buds of Thunb. The structures of these compounds were elucidated based on spectroscopic analysis (HR-ESI-MS, NMR), and the absolute configurations of and were determined by comparison of their electronic circular dichroism (ECD) spectra with literature and theoretical calculation. The anti-inflammatory activities of the isolates were evaluated by measuring their inhibitory effects on PGE and IL-6 production in LPS stimulated RAW 264. Read More

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Dietary Supplementation With Chlorogenic Acid Derived From Improves Meat Quality and Muscle Fiber Characteristics of Finishing Pigs via Enhancement of Antioxidant Capacity.

Front Physiol 2021 20;12:650084. Epub 2021 Apr 20.

Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, School of Life Sciences, Hunan Normal University, Changsha, China.

Chlorogenic acid (CGA), one of the most abundant polyphenol compounds in nature, is regarded as a potential feed additive to promote animal health and enhance the meat products' quality via its various biological properties. The current study aims: (1) to determine whether dietary CGA supplementation improves meat quality and muscle fiber characteristics, and (2) to ascertain whether the corresponding improvement is associated with enhancing the antioxidant capacity of the finishing pigs. Thirty-two (Large × White × Landrace) finishing pigs with an average initial body weight of 71. Read More

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Phloem-Feeding Herbivores Affect Floral Development and Reproduction in the Etruscan Honeysuckle ( Santi).

Plants (Basel) 2021 Apr 20;10(4). Epub 2021 Apr 20.

Department of Plant Biology and Soil Sciences, Campus Lagoas-Marcosende, University of Vigo, 36310 Vigo, Spain.

Floral development depends on multifactor processes related to genetic, physiological, and ecological pathways. Plants respond to herbivores by activating mechanisms aimed at tolerating, compensating, or avoiding loss of biomass and nutrients, and thereby survive in a complex landscape of interactions. Thus, plants need to overcome trade-offs between development, growth, and reproduction vs. Read More

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sp. nov., a novel ascomycetous yeast species associated with the Georgian honeysuckle ( M. Bieb.).

Int J Syst Evol Microbiol 2021 Apr;71(4)

Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Brunswick, 38124, Germany.

During an investigation of the yeast communities associated with wild fruit shrubs in Dagestan (Caucasus, Russia), four fermenting ascospore-producing yeast strains were isolated from leaves of the Georgian honeysuckle ( M. Bieb.) and from soil underneath this plant. Read More

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Potential Role of Gut Microbiota in Traditional Chinese Medicine against COVID-19.

Am J Chin Med 2021 9;49(4):785-803. Epub 2021 Apr 9.

Key Laboratory of Shaanxi Administration of Traditional Chinese, Medicine for TCM Compatibility, State Key Laboratory of Research and Development of Characteristic, Qin Medicine Resources (Cultivation), Shaanxi Collaborative Innovation Center of Chinese Medicinal, Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, P. R. China.

The coronavirus disease 2019 (COVID-19) spreads and rages around the world and threatens human life. It is disappointing that there are no specific drugs until now. The combination of traditional Chinese medicine (TCM) and western medication seems to be the current more effective treatment strategy for COVID-19 patients in China. Read More

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Chlorogenic Acid Inhibits Human Glioma U373 Cell Progression via Regulating the SRC/MAPKs Signal Pathway: Based on Network Pharmacology Analysis.

Drug Des Devel Ther 2021 30;15:1369-1383. Epub 2021 Mar 30.

Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.

Introduction: Chlorogenic acid (CGA) is a type of polyphenolic substance that is widely extracted from many traditional Chinese medicines (eg, Thunb, Oliver) and exhibits a wide range of anti-tumor effects. However, the potential molecular mechanisms of CGA in glioma U373 cells remain unclear.

Methods: Network pharmacology analysis was used to explore the potential therapeutic targets of CGA in glioma. Read More

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Bioactive Compounds, Antioxidant, and Antibacterial Properties of Berries: Evaluation of 11 Cultivars.

Plants (Basel) 2021 Mar 25;10(4). Epub 2021 Mar 25.

Botanical Garden, Vytautas Magnus University, LT-46324 Kaunas, Lithuania.

The aim of the study was to evaluate 11 cultivars of blue honeysuckle ( L.) for bioactive compounds, antioxidant capacity, and the antibacterial activity of berries. Total phenolic contents (TPCs) and total anthocyanin contents (TACs) were established by using ethanolic extracts. Read More

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The complete chloroplast genome of Hsu et S. C. Cheng and its phylogenetic analysis.

Mitochondrial DNA B Resour 2021 Mar 15;6(3):842-843. Epub 2021 Mar 15.

School of Life Science, Guizhou Normal University, Guiyang, China.

Hsu et S. C. Cheng is widely used as an edible and medicinal food in China and also displays excellent pharmacological activities. Read More

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Cloning and expression of gene in two varieties.

J Genet 2021 ;100

College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, People's Republic of China.

is an important regulator for flowering in plants and critical in controlling the morphogenesis of flower organs. The fulllength cDNAs of in conventional Lonicera macranthoides () and the mutant '' cultivar () were obtained using rapid amplification of cDNA ends and the expression vectors for were constructed to investigate the roles of in the cultivar. (GenBank: MK419948) and (GenBank: MK419948) were isolated from the conventional variety and '' cultivar respectively. Read More

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January 2021

Multi-marker scans coupled to high-resolution mass spectrometry strategy for global profiling combined with structure recognition of unknown trace chlorogenic acids in Lonicera Flos.

Talanta 2021 May 22;226:122134. Epub 2021 Jan 22.

Institute of Food Safety, Chinese Academy of Inspection & Quarantine, Beijing, 100176, China. Electronic address:

Deep investigation, profiling of chemical diversity of constituent compounds and discovery of novel structures is a great challenge. A novel comprehensive and effective approach to mine trace unknown compounds combined with structure recognition in complex matrix is developed, in order to profiling potential Chlorogenic acids (CGAs) in Lonicera Flos (LFs): using multiple neutral loss/precursor ion (NL/PI) markers scans combined with high resolution mass spectrometry (HRMS). The workflow included (i) Fragmentation rules deduced by Q-orbitrap and selection of multiple NL/PI markers. Read More

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Honeysuckle Aqueous Extracts Induced Suppress EV71 Replication and Pathogenesis In Vitro and In Vivo and Is Predicted to Inhibit SARS-CoV-2.

Viruses 2021 02 16;13(2). Epub 2021 Feb 16.

Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.

Honeysuckle ( Thunb) is a traditional Chinese medicine (TCM) with an antipathogenic activity. MicroRNAs (miRNAs) are small non-coding RNA molecules that are ubiquitously expressed in cells. Endogenous miRNA may function as an innate response to block pathogen invasion. Read More

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February 2021

The complete chloroplast genome of Miq (Caprifoliaceae: Dipsacales) from Guangxi, China.

Mitochondrial DNA B Resour 2021 Feb 9;6(2):450-451. Epub 2021 Feb 9.

School of Life Science, Guizhou Normal University, Guiyang, China.

Miq, which is widely distribute in south China, is an important Chinese plant used in traditional medicine. Here we report the first complete chloroplast (cp) genome sequence of this species. The circular cp genome is 154,581 bp in size, including a large single-copy (LSC) region of 88,379 bp and a small single-copy (SSC) region of 18,646 bp, which were separated by two inverted repeat (IR) regions (IRA and B, 23,778 bp each). Read More

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February 2021

A Network Pharmacology Study on the Molecular Mechanisms of FDY003 for Breast Cancer Treatment.

Evid Based Complement Alternat Med 2021 6;2021:3919143. Epub 2021 Feb 6.

The Fore, 87 Ogeum-ro, Songpa-gu, Seoul 05542, Republic of Korea.

Herbal medicines have drawn considerable attention with regard to their potential applications in breast cancer (BC) treatment, a frequently diagnosed malignant disease, considering their anticancer efficacy with relatively less adverse effects. However, their mechanisms of systemic action have not been understood comprehensively. Based on network pharmacology approaches, we attempted to unveil the mechanisms of FDY003, an herbal drug comprised of Thunberg, Thunberg, and , against BC at a systemic level. Read More

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February 2021

Integrated metabolic profiling and transcriptome analysis of pigment accumulation in Lonicera japonica flower petals during colour-transition.

BMC Plant Biol 2021 Feb 17;21(1):98. Epub 2021 Feb 17.

Key Laboratory of Horticulture Science for Southern Mountains Regions of Ministry of Education; College of Horticulture and Landscape Architecture, Southwest University, Chongqing, 400715, China.

Background: Plants have remarkable diversity in petal colour through the biosynthesis and accumulation of various pigments. To better understand the mechanisms regulating petal pigmentation in Lonicera japonica, we used multiple approaches to investigate the changes in carotenoids, anthocyanins, endogenous hormones and gene expression dynamics during petal colour transitions, i.e. Read More

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February 2021

Variations in morphology, physiology, and multiple bioactive constituents of Lonicerae Japonicae Flos under salt stress.

Sci Rep 2021 Feb 16;11(1):3939. Epub 2021 Feb 16.

College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.

Lonicerae Japonicae Flos (LJF) is an important traditional Chinese medicine for the treatment of various ailments and plays a vital role in improving global human health. However, as unable to escape from adversity, the quality of sessile organisms is dramatically affected by salt stress. To systematically explore the quality formation of LJF in morphology, physiology, and bioactive constituents' response to multiple levels of salt stress, UFLC-QTRAP-MS/MS and multivariate statistical analysis were performed. Read More

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February 2021

Toxicity as prime selection criterion among SARS-active herbal medications.

Phytomedicine 2021 May 28;85:153476. Epub 2021 Jan 28.

Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, 55128, Mainz, Germany.

We present here a new selection criterion for prioritizing research on efficacious drugs for the fight against COVID-19: the relative toxicity versus safety of herbal medications, which were effective against SARS in the 2002/2003 epidemic. We rank these medicines according to their toxicity versus safety as basis for preferential rapid research on their potential in the treatment of COVID-19. The data demonstrate that from toxicological information nothing speaks against immediate investigation on, followed by rapid implementation of Lonicera japonica, Morus alba, Forsythia suspensa, and Codonopsis spec. Read More

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Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos.

Chin J Nat Med 2021 Jan;19(1):70-80

NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine, Shanghai Institute for Food and Drug Control, Shanghai 201203, China. Electronic address:

Pesticides' overuse and misuse have been reported to induce ingredient variations in herbal medicine, which is now gaining attention in the medicinal field as a form of alternative medicine. To date, available studies on pesticide-induced ingredient variations of herbal medicine are limited only on a few compounds and remain most others unexamined. In this study, a plant metabolomics-based strategy was performed to systematically explore the effects of two frequently used insecticides on the comprehensive constituents of Lonicerae Japonicae Flos (LJF), the flower buds of Lonicera japonica Thunb. Read More

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January 2021

[Research on remote sensing recognition of wild planted Lonicera japonica based on deep convolutional neural network].

Zhongguo Zhong Yao Za Zhi 2020 Dec;45(23):5658-5662

State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700, China.

Identification of Chinese medicinal materials is a fundamental part and an important premise of the modern Chinese medicinal materials industry. As for the traditional Chinese medicinal materials that imitate wild cultivation, due to their scattered, irregular, and fine-grained planting characteristics, the fine classification using traditional classification methods is not accurate. Therefore, a deep convolution neural network model is used for imitating wild planting. Read More

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December 2020

Protective Role of a New Polysaccharide Extracted from in Mice with Ulcerative Colitis Induced by Dextran Sulphate Sodium.

Biomed Res Int 2021 2;2021:8878633. Epub 2021 Jan 2.

Geneis Beijing Co., Ltd., Beijing 100102, China.

is a traditional Chinese herbal medicine for treating intestinal inflammation. The extraction method of polysaccharide (LJP) has been developed previously by our research group. In this study, a Fourier transform infrared spectrometer (FT-IR) was used to perform a qualitative analysis of LJP and a precolumn derivatization high-performance liquid chromatography (HPLC) ((Palo Alto, CA, USA) method was used to explore the monosaccharide composition of LJP. Read More

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January 2021

Dissecting the novel mechanism of reduning injection in treating Coronavirus Disease 2019 (COVID-19) based on network pharmacology and experimental verification.

J Ethnopharmacol 2021 Jun 22;273:113871. Epub 2021 Jan 22.

State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang, Jiangsu, 222001, China; The Key Laboratory for the New Technique Research of TCM Extraction and Purification, Lianyungang, Jiangsu, 222047, China. Electronic address:

Ethnopharmacological Relevance: Reduning injection (RDNI) is a patented Traditional Chinese medicine that contains three Chinese herbal medicines, respectively are the dry aboveground part of Artemisia annua L., the flower of Lonicera japonica Thunb., and the fruit Gardenia jasminoides J. Read More

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Glycosides of Caulis Lonicerae inhibits the inflammatory proliferation of IL-1β-mediated fibroblast-like synovial cells cocultured with lymphocytes.

Phytother Res 2021 Jan 23. Epub 2021 Jan 23.

Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.

Caulis Lonicerae, the dried stem of Lonicera japonica, has been confirmed to have antiinflammatory and antioxidant therapeutic effects. In the present study, we aimed to evaluate the functional mechanism of glycosides extracted from Caulis Lonicerae on the inflammatory proliferation of interleukin-1 beta (IL-1β)-mediated fibroblast-like synoviocytes (FLSs) from rats. Rat FLSs (RSC-364) co-cultured with lymphocytes induced by IL-1β were used as a cell model. Read More

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January 2021

Phenolic Profiles, Antioxidant Activity and Phenotypic Characterization of L. Berries, Cultivated in Lithuania.

Antioxidants (Basel) 2021 Jan 15;10(1). Epub 2021 Jan 15.

Lithuanian Research Centre for Agriculture and Forestry, Institute of Horticulture, Kauno str. 30, Babtai, LT-54333 Kaunas, Lithuania.

L. is an early fruit-bearing plant that originates from harsh environments. Raw materials contain a body of different phenolic origin compounds that determine the multidirectional antioxidant and pharmacological activities. Read More

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January 2021

Characteristic of the complete chloroplast genome of , an important ornamental plant endemic to China.

Mitochondrial DNA B Resour 2020 Aug 14;5(3):3170-3171. Epub 2020 Aug 14.

College of Plant Protection, Henan Agricultural University, Zhengzhou, China.

is an important ornamental plant in China. Due to the lack of efficient molecular markers, although recent studies supported that was phylogenetically closely related to , , , and , relationships among these taxa remained uncertain. To examine the phylogenetic position of within Caprifoliaceae, we characterized the complete chloroplast (cp) genome of . Read More

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Reduning injection and its effective constituent luteoloside protect against sepsis partly via inhibition of HMGB1/TLR4/NF-κB/MAPKs signaling pathways.

J Ethnopharmacol 2021 Apr 7;270:113783. Epub 2021 Jan 7.

Pharmaceutical Informatics Institute, College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. Electronic address:

Ethnopharmacological Relevance: Reduning injection (RDN), a popular traditional Chinese medicine, formulated by three herbs (i.e., Artemisia carvifolia Buch. Read More

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First records of powdery mildew fungi (Erysiphales) on medicinal plants in Taiwan.

Bot Stud 2021 Jan 6;62(1). Epub 2021 Jan 6.

School of Forestry & Resource Conservation, National Taiwan University, Taipei, Taiwan.

Background: Production of medicinal plants in Taiwan is not only hampered by international market competition, but also lack of knowledge of their pathogens, such as powdery mildew fungi (Erysiphales, Ascomycota). Records of these fungi in Taiwan originate from few researchers for the last one hundred years and are still incomplete. Since powdery mildews in tropical/subtropical environments rarely develop the sexual stages with morphologically diagnostic characteristics, internal transcribed spacer sequences (ITS) of the ribosomal RNA genes obtained from the asexual stages have become important modern tools for species identification. Read More

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January 2021

Chemical Composition of a Novel Distillate from Fermented Mixture of Nine Anti-Inflammatory Herbs and Its UVB-Protective Efficacy in Mouse Dorsal Skin via Attenuating Collagen Disruption and Inflammation.

Molecules 2020 Dec 29;26(1). Epub 2020 Dec 29.

Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.

Since ancient times, various herbs have been used in Asia, including Korea, China, and Japan, for wound healing and antiaging of the skin. In this study, we manufactured and chemically analyzed a novel distillate obtained from a fermented mixture of nine anti-inflammatory herbs (, , , , , , ., , and ). Read More

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December 2020

The complete chloroplast genome of the (Caprifoliaceae), an ornamental plant.

Mitochondrial DNA B Resour 2020 Jan 14;5(1):560-561. Epub 2020 Jan 14.

Xi'an International University, Xi'an, People's Republic of China.

, is scattered in west and northeast China as well as adjacent Korea, Japan and the Soviet union. Here, we assembled and characterized the complete chloroplast (cp) genome of using Illumina sequencing data for the first time. The complete cp genome was 155,337 bp in length, consisting of a pair of inverted repeats of 23,718 bp, a large single-copy region of 89,221 bp and a small single-copy region of 18,680 bp. Read More

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January 2020

Characterization of the complete chloroplast genome of (Caprifoliaceae), a long history herb species plant from China.

Jiang Luo

Mitochondrial DNA B Resour 2019 Nov 12;4(2):3936-3937. Epub 2019 Nov 12.

Jiangxi Province Hospital of Integrated Chinese and Western Medicine, Nanchang, P. R. China.

is a common ornamental and medicinal plant in North America and East Asia. In this study, the complete chloroplast genome of was presented and annotated. The chloroplast genome of is 155,078 bp in length, which has a large single-copy (LSC) region of 88,859 bp, a small single-copy region (SSC) of 18,647 bp, and a pair of inverted-repeat (IRs) regions of 23,786 bp in each one. Read More

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November 2019

Complementary Chinese Herbal Medicine Therapy Improves Survival in Patients With Pemphigus: A Retrospective Study From a Taiwan-Based Registry.

Front Pharmacol 2020 9;11:594486. Epub 2020 Dec 9.

School of Chinese Medicine, China Medical University, Taichung, Taiwan.

Pemphigus is a life-threatening and skin-specific inflammatory autoimmune disease, characterized by intraepidermal blistering between the mucous membranes and skin. Chinese herbal medicine (CHM) has been used as an adjunct therapy for treating many diseases, including pemphigus. However, there are still limited studies in effects of CHM treatment in pemphigus, especially in Taiwan. Read More

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December 2020

[Study on anti-inflammatory mechanism of Lonicera fulvotometosa on acute lung injury model in rats].

Zhongguo Zhong Yao Za Zhi 2020 Oct;45(20):4978-4983

School of Pharmacy, Guizhou University of Traditional Chinese Medicine Guiyang 550025, China National & Local Joint Engineering Research Center for the Exploitation and Utilization Technology of Medicine and Food Dual-use Resources in the Southwest of China Guiyang 550025, China.

To study the effect of Lonicera fulvotometosa(LFH) on expression of genes related to inflammatory pathways in the lung tissue of rats with acute lung injury(ALI) induced by lipopolysaccharide(LPS), explore the lung-protective effects and inflammatory mechanisms of L. fulvotometosa water extract, and provide experimental and theoretical basis for the clinical application of LFH. Forty SD rats were randomly divided into 4 groups: normal group, model group(LPS, 5 mg·kg~(-1)), LFH group(7. Read More

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October 2020