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Long-term Follow Up of Ileal Ureteral Replacement for Complex Ureteral Strictures: Single Institution Study.

Urology 2021 Jul 23. Epub 2021 Jul 23.

Department of Surgery, Division of Urology, University of Colorado School of Medicine, Aurora, CO. Electronic address:

Objective: To report our 16 year experience with ileal ureter interposition for complex ureteral stricture. Ureteral reconstruction continues to evolve to include less invasive techniques to successfully manage ureteral stricture. However, long, complex, obliterative and especially radiated ureteral strictures are not amenable to less invasive techniques and may require Ileal ureter interposition. Read More

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Pricing through health apps generated data-Digital dividend as a game changer: Discrete choice experiment.

PLoS One 2021 26;16(7):e0254786. Epub 2021 Jul 26.

WHU -Otto Beisheim School of Management, Chair of Digital Marketing, Vallendar, GER.

Objectives: The objective of this paper is to study under which circumstances wearable and health app users would accept a compensation payment, namely a digital dividend, to share their self-tracked health data.

Methods: We conducted a discrete choice experiment alternative, a separated adaptive dual response. We chose this approach to reduce extreme response behavior, considering the emotionally-charged topic of health data sales, and to measure willingness to accept. Read More

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Implantation of one, two or multiple MitraClips for transcatheter mitral valve repair: insights from a 1824-patient multicenter study.

Panminerva Med 2021 Jul 26. Epub 2021 Jul 26.

Division of Cardiology, Centro Alte Specialità e Trapianti (CAST), Azienda Ospedaliero-Universitaria Policlinico-Vittorio Emanuele, University of Catania, Catania, Italy.

Background: Transcatheter mitral valve repair (TMVR) with the MitraClip device is an established treatment for mitral regurgitation (MR). More than one MitraClip may be implanted if a single one does not reduce MR adequately. We aimed at appraising the outlook of patients undergoing implantation of one, two or multiple MitraClips for TMVR. Read More

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Contemporary management of benign uretero-enteric strictures after cystectomy: a systematic review.

Minerva Urol Nephrol 2021 Jul 26. Epub 2021 Jul 26.

Urology Department, Sant'Andrea Hospital, Università degli Studi di Roma La Sapienza, Rome, Italy.

Introduction: Uretero-enteric stricture (UES) is a common post-operative complication after radical cystectomy with urinary diversion. The aim of this systematic review is to discuss the contemporary management of benign UES after cystectomy and to compare the different surgical approaches.

Evidence Acquisition: A systematic review was performed from January 2000 through January 2021. Read More

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Twenty-four hour ex-vivo normothermic machine perfusion in rat livers.

Technology (Singap World Sci) 2020 Mar-Jun;8(1-2):27-36. Epub 2020 Nov 5.

Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Ex-vivo liver perfusion (EVLP) is an ideal platform to study liver disease, therapeutic interventions, and pharmacokinetic properties of drugs without any patient risk. Rat livers are an ideal model for EVLP due to less organ quality variability, ease of hepatectomy, well-defined molecular pathways, and relatively low costs compared to large animal or human perfusions. However, the major limitation with rat liver normothermic machine perfusion (NMP) is maintaining physiologic liver function on an ex-vivo machine perfusion system. Read More

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November 2020

Grief in Response to Uncertainty Distress Among Veterinary Students During the Early Stages of the COVID-19 Pandemic.

Front Vet Sci 2021 8;8:662198. Epub 2021 Jul 8.

College of Veterinary Medicine, Lincoln Memorial University, Harrogate, TN, United States.

The abrupt and life-altering shifts brought on by the COVID-19 pandemic have stimulated research in fields ranging from social sciences to virology. This study explored perceptions and experiences of COVID-19's impact on students at Lincoln Memorial University-College of Veterinary Medicine (LMU-CVM) and considered how to respond to these. Semistructured interviews were conducted with 20 students from LMU-CVM. Read More

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Measuring for Success: Evaluating Leadership Training Programs for Sustainable Impact.

Ann Glob Health 2021 12;87(1):63. Epub 2021 Jul 12.

Emerita, University of Washington.

Background: In an era of global health security challenges such as the COVID-19 pandemic, there is greater need for strong leadership. Over the past decades, significant investments have been made in global health leadership development programs by governments and philanthropic organizations to address this need. Evaluating the societal impact of these programs remains challenging, despite consensus on the importance of public health leadership. Read More

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Experiential Learning and Mentorship in Global Health Leadership Programs: Capturing Lessons from Across the Globe.

Ann Glob Health 2021 12;87(1):61. Epub 2021 Jul 12.

Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.

Objectives: The changing global landscape of disease and public health crises, such as the current COVID-19 pandemic, call for a new generation of global health leaders. As global health leadership programs evolve, many have incorporated experiential learning and mentoring (ELM) components into their structure. However, there has been incomplete consideration on how ELM activities are deployed, what challenges they face and how programs adapt to meet those challenges. Read More

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The clinical study of CBCT imaging technology in the restoration of upper anterior teeth of the elderly.

Am J Transl Res 2021 15;13(6):7022-7028. Epub 2021 Jun 15.

Geriatric Department, Second Hospital Baoding City Baoding, China.

Objective: To evaluate and analyze the clinical effect of CBCT imaging technology on the restoration of upper anterior teeth of the elderly.

Methods: 36 elderly patients with upper anterior teeth loss in our hospital from January 2018 to January 2020 were selected for implant restoration. Patients were equally randomized into a curved tomographic restoration group (TR group) and a CBCT restoration group (CR group). Read More

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A Review of Telemedicine Interventions for Weight Loss.

Curr Cardiovasc Risk Rep 2021 15;15(9):17. Epub 2021 Jul 15.

Department of Family Medicine and Community Health, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 USA.

Purpose Of Review: Telemedicine has become popular as an alternative for in-person weight loss treatment during the COVID-19 pandemic. This review focuses on weight loss interventions utilizing real-time telemedicine.

Recent Findings: Telemedicine interventions are usually run as a weekly counseling and educational session or as a complement to a primarily Web-based intervention. Read More

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Applying Attention-Based Models for Detecting Cognitive Processes and Mental Health Conditions.

Cognit Comput 2021 Jul 17:1-18. Epub 2021 Jul 17.

Idiap Research Institute, Rue Marconi 19, 1920, Martigny, Switzerland.

According to the psychological literature, implicit motives allow for the characterization of behavior, subsequent success, and long-term development. Contrary to personality traits, implicit motives are often deemed to be rather stable personality characteristics. Normally, implicit motives are obtained by Operant Motives, unconscious intrinsic desires measured by the Operant Motive Test (OMT). Read More

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Soft-tissue reconstruction in lower-leg fracture-related infections: An orthoplastic outcome and risk factor analysis.

Injury 2021 Jul 16. Epub 2021 Jul 16.

Center for Musculoskeletal Infections, University Hospital Basel, Spitalstrasse 21, Basel CH-4031 Switzerland; Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Basel, Switzerland.

Introduction Fracture-related infection (FRI) is a severe post-traumatic complication which is occasionally accompanied by a deficient or even avital soft-tissue envelope. In these cases, a thoroughly planned orthoplastic approach is imperative as a vital and intact soft-tissue envelope is mandatory to achieve fracture union and infection eradication. The aim of this study was, to analyse if soft-tissue reconstruction (STR) without complications is associated with a better long-term outcome compared to FRI patients with STR complications. Read More

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[The effect of endoscopic dacryocystorhinostomy on different lacrimal duct obstruction].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Aug;35(8):677-682

Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Key Laboratory of Otolaryngology Head and Neck Surgery(Capital Medical University),Ministry of Education,Beijing,100730,China.

To observe the effect of endoscopic dacryocystorhinostomy on different lacrimal duct obstruction. Eighty eyes with the lacrimal passage obstruction were collected, and treated with endoscopic dacryocystorhinostomy. Meanwhile, the abnormal structures of the nasal cavity were corrected and the pathological changes of the nasal cavity and sinuses were treated. Read More

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Pediatric brain tumors: the era of molecular diagnostics, targeted and immune-based therapeutics, and a focus on long term neurologic sequelae.

Curr Probl Cancer 2021 Jul 16:100777. Epub 2021 Jul 16.

Ann and Robert H. Lurie Children's Hospital of Chicago. Division of Hematology/Oncology/Stem Cell Transplantation/Neuro-Oncology. Chicago, Illinois.

Pediatric brain tumors are the second most common malignancy of childhood after acute leukemia and the number one cause of cancer-related mortality. Over the past decade, advanced molecular diagnostics have led to the discovery of new molecularly-defined tumor types with prognostic and therapeutic implications. Methylation profiles, whole genome sequencing, and transcriptomics have defined subgroups and revealed heterogeneity within commonly defined tumor entities. Read More

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Multinucleated Giant Cells Induced by a Silk Fibroin Construct Express Proinflammatory Agents: An Immunohistological Study.

Materials (Basel) 2021 Jul 19;14(14). Epub 2021 Jul 19.

Department for Oral, Cranio-Maxillofacial and Facial Plastic Surgery, FORM (Frankfurt Orofacial Regenerative Medicine) Lab, University Hospital Frankfurt Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

Multinucleated giant cells (MNGCs) are frequently observed in the implantation areas of different biomaterials. The main aim of the present study was to analyze the long-term polarization pattern of the pro- and anti-inflammatory phenotypes of macrophages and MNGCs for 180 days to better understand their role in the success or failure of biomaterials. For this purpose, silk fibroin (SF) was implanted in a subcutaneous implantation model of Wistar rats as a model for biomaterial-induced MNGCs. Read More

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A Framework for Long-Term Vibration-Based Monitoring of Bridges.

Sensors (Basel) 2021 Jul 11;21(14). Epub 2021 Jul 11.

Department of Civil Engineering and Energy Technology, Oslo Metropolitan University, Pilestredet 35, 0166 Oslo, Norway.

A new framework for long-term monitoring of bridges is proposed in order to negate (i) the impact of measurement uncertainties on damage detection in vibration-based structural health monitoring and (ii) the low sensitivity of damage indicators to low levels of damage. The framework is developed using three vibration-based damage indicators that have an intuitive physical correlation with damage: modal curvature, modal strain energy and modal flexibility. The article first quantifies the efficacy of these damage indicators when based on two observations, one from the undamaged state and one from the monitored state, in detecting and locating damage for different damage levels that are simulated on an 84-m long railway bridge. Read More

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Long-Term Outcome with New Generation Prostheses in Patients Undergoing Transcatheter Aortic Valve Replacement.

J Clin Med 2021 Jul 14;10(14). Epub 2021 Jul 14.

Department of Cardiology, Cardiology I, University Medical Center Mainz, Johannes Gutenberg University, Langenbeckstr. 1, 55131 Mainz, Germany.

The aim of this study was to compare patients with transcatheter aortic valve replacement (TAVR) receiving new generation prostheses SAPIEN 3 (S3, Edwards Lifesc.) and Evolut R (ER, Medtronic Inc.) in terms of periprocedural and long-term outcome. Read More

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Digital Implant Planning and Surgical Guides: Tools for Clinical Success.

Compend Contin Educ Dent 2021 Jul-Aug;42(7):400-401

Department of Preventive and Restorative Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania.

Digital technologies have fundamentally changed treatment planning, surgical placement, and restoration of dental implants, improving clinical success while saving valuable chairtime. Intraoral scanners (IOS), cone-beam computed tomography (CBCT), 3D implant planning software, and CAD/CAM systems that fabricate surgical guides and provisional and definitive restorations have become standard tools for precise implant placement and ideal restoration design, which are essential for optimal and long-term esthetic and functional success. This article summarizes clinical guidelines for integration of digital technologies in implant dentistry. Read More

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Long-Term Esthetic Complications Associated With Anterior Implant-Supported Restorations.

Compend Contin Educ Dent 2021 Jul-Aug;42(7):358-363; quiz 364

Clinical Professor in Periodontology, Department of Periodontology, Hadassah Medical Center, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Having demonstrated high average survival rates, osseointegrated endosseous dental implants are considered a predictable solution for the replacement of missing teeth. Most studies and case reports have concentrated on the success and/or failure of dental implant-supported restorations in the posterior regions of the mouth, while fewer reports have investigated the performance of such treatments in the esthetic segment. Today, it is recognized that in addition to implant survival, other parameters of implant dentistry are considerations when evaluating success or failure in the esthetic zone. Read More

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Narrative review of male urethral sling for post-prostatectomy stress incontinence: sling type, patient selection, and clinical applications.

Transl Androl Urol 2021 Jun;10(6):2682-2694

Department of Urology, Mayo Clinic, Rochester, MN, USA.

Male stress urinary incontinence (SUI) following prostate treatment is a devastating complaint for many patients. While the artificial urinary sphincter is the gold standard treatment for male SUI, the urethral sling is also popular due to ease of placement, lack of mechanical complexity, and absence of manual dexterity requirement. A literature review was performed of male urethral sling articles spanning the last zz20 years using the PubMed search engine. Read More

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Legacies of Environmental Injustice on Neighborhood Violence, Poverty and Active Living in an African American Community.

Ethn Dis 2021 15;31(3):425-432. Epub 2021 Jul 15.

Department of Public Health Education, University of North Carolina at Greensboro, NC.

Features of the built environment such as parks and open spaces contribute to increased physical activity in populations, while living in neighborhoods with high poverty, racial/ethnic segregation, presence of neighborhood problems, and violence has been associated with less active living. Our present study examined the factors that may facilitate or hinder the long-term success of built environment interventions aimed at promoting physical activity in communities with a legacy of environmental injustice. The data for this study came from a larger assessment of the impact of a new local park in Newark, NJ. Read More

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Treatment of Kyphosis Arising Secondary to Laminectomy and Irradiation in the Pediatric Population.

Orthopedics 2021 Jul-Aug;44(4):e563-e569. Epub 2021 Jul 1.

The effects of radiation therapy and laminectomy on the growing spine have been well documented. Due to compromised bone quality after irradiation, spinal fusion has a high failure rate. The aim of this study was to evaluate treatment of post-laminectomy and post-irradiation kyphosis in children using a vascularized rib graft (VRG) to augment anterior spinal fusion and posterior spinal fusion. Read More

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Newborn Screening in the Diagnosis of Primary Immunodeficiency.

Lisa J Kobrynski

Clin Rev Allergy Immunol 2021 Jul 22. Epub 2021 Jul 22.

Pediatrics Institute, Emory University and Children's Healthcare of Atlanta, Atlanta, GA, USA.

Newborn screening for severe combined immune deficiency (SCID) is the first inborn error of immunity (IEI) to be detected through population screening. It also represents the first newborn screening test to utilize molecular testing on DNA from newborn dried blood spots. Newborn screening for SCID has provided opportunities to measure the population prevalence of this disorder and evaluate the effect of early interventions on the overall outcomes in affected infants. Read More

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Renal artery embolization for spontaneous hemorrhage in patients with acquired cystic kidney disease: A 20-year single-center experience.

Pak J Med Sci 2021 Jul-Aug;37(4):1111-1117

Hee Ho Chu, MD. Department of Radiology and Research Institute of Radiology, Asan Medical Center, Seoul, Korea.

Objectives: To evaluate the safety and effectiveness of transcatheter arterial embolization for controlling spontaneous hemorrhage in patients with acquired cystic kidney disease (ACKD).

Methods: This retrospective study included 18 patients with ACKD (M:F=13:5; mean age, 56 years) who underwent renal artery embolization to control spontaneous hemorrhage between January 2001 and September 2020. The underlying etiology and clinical presentations were reviewed and previous computed tomography (CT) findings were analyzed. Read More

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December 2020

Endodontic retreatment and bioceramics: A case report.

J Biol Regul Homeost Agents 2021 May-Jun;35(3 Suppl. 1):147-153

Department of Social Dentistry and Gnathological Rehabilitation, National Institute for Health, Migration and Poverty (NIHMP), Rome, Italy.

The success rate in endodontic retreatment can be significantly boosted by using materials that guarantee both intimate adhesion to the canal walls and long-term stability. Bioceramic cements used in root filling show interesting properties including extraordinary sealing capacities, antimicrobial activity that stimulates periapical healing and the continuous production of hydroxyopathitis for a long time. This case report deals with the application of bioceramic cement in endodontic retreatment. Read More

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Early Revision after Artificial Urinary Sphincter Implantation Does Not Impair the Long-Term Treatment Success.

Urol Int 2021 Jul 21:1-8. Epub 2021 Jul 21.

Department of Urology, University of Regensburg, Caritas St. Josef Medical Centre, Regensburg, Germany,

Introduction: After implantation of an artificial urinary sphincter (AUS) due to stress urinary incontinence, in some cases revision procedures may be necessary. This is mostly due to device infection or cuff erosion in the long term. The aim of this study was to evaluate the impact of early revision procedures (prior to or immediately after AUS activation) on the long-term outcome. Read More

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Current practice in Transvenous Lead Extraction in Latin-America: Latin-American Heart Rhythm Association Survey.

J Cardiovasc Electrophysiol 2021 Jul 20. Epub 2021 Jul 20.

Sanatorio de La Trinidad de San Isidro, Buenos Aires, Argentina.

Background: Transvenous lead extraction (TLE) is standard of care for the management of patients with cardiac implantable electronic device infection or lead related complications. Currently, objective data on TLE in Latin America is lacking.

Objective: To describe the current practice standards in Latin American centers performing TLE. Read More

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Short vs. regular length implants to rehabilitate partially edentulous mandible: a 2-year prospective split-mouth clinical study.

J Oral Implantol 2021 Jul 20. Epub 2021 Jul 20.

Tufts University.

Many studies have evaluated short implants (SIs); however, it is still unclear whether SIs are reliable and can be used to simplify surgical and prosthetic protocols with successful clinical outcomes. The aim of this non-random, conveniently sampled, prospective, split-mouth study was to compare the clinical outcomes when short (SI) (≤8 mm) or regular-length implants (RIs) (>10 mm) were used in the posterior mandible two years after the delivery of splinted reconstructions. Each participant (N=10) received four implants in the posterior mandible; two SIs were placed on one side, and two RIs were placed contra-laterally. Read More

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Oncological Children and Well-Being: Occupational Performance and HRQOL Change after Fine Motor Skills Stimulation Activities.

Pediatr Rep 2021 Jul 5;13(3):383-400. Epub 2021 Jul 5.

Province College for Health-Care Professions Claudiana, 39100 Bozen, Italy.

Cancer children experience long periods of hospitalization, which are associated with limited performance in several developmental domains and participation restrictions in age appropriate occupations. Fine motor abilities represent building blocks in performing daily life skills and have been found to be closely connected with later academic success. Moreover, medical and psychological sequelae for cancer inpatients may result in diminished daily activities functioning, poor perceived health related quality of life (HRQOL), and increase the likelihood of long-term impairments. Read More

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Quality of life of patients with 3D-printed arm prostheses in a rural area of Sierra Leone.

Heliyon 2021 Jul 2;7(7):e07447. Epub 2021 Jul 2.

Department of Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.

Introduction: In Sierra Leone, access to prostheses is limited due to absence of practical knowledge, materials, trained staff, and high cost. This paper investigates the impact of a 3D printed prosthesis on the health-related quality of life (HRQoL) in prosthesis recipients.

Methods: Patients with upper extremity amputations were included in this case study from December 2018 until July 2019. Read More

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