16,831 results match your criteria long-term hemorrhage


CT findings and the prognostic value of the Koret CT score in cats with traumatic brain injury.

J Feline Med Surg 2021 Apr 13:1098612X211005306. Epub 2021 Apr 13.

Department of Neurology and Neurosurgery, Koret School of Veterinary Medicine Teaching Hospital, Hebrew University of Jerusalem, Rehovot, Israel.

Objectives: The aims of this study were to evaluate associations between abnormal head CT findings and outcome, and to examine the prognostic value of the Koret CT score (KCTS) in cats sustaining acute traumatic brain injury (TBI).

Methods: The medical records of cats hospitalised with TBI that underwent head CT scans within 72 h of admission were retrospectively reviewed. CT scans were evaluated independently by a radiologist and a neurologist who were blinded to the outcome. Read More

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Association of Dose of Intracranial Hypertension with Outcome in Subarachnoid Hemorrhage.

Neurocrit Care 2021 Apr 12. Epub 2021 Apr 12.

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Background: In patients with aneurysmal subarachnoid hemorrhage (aSAH) the burden of intracranial pressure (ICP) and its contribution to outcomes remains unclear. In this multicenter study, the independent association between intensity and duration, or "dose," of episodes of intracranial hypertension and 12-month neurological outcomes was investigated.

Methods: This was a retrospective analysis of multicenter prospectively collected data of 98 adult patients with aSAH amendable to treatment. Read More

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Associations of behaviors, biological phenotypes and cardiovascular health with risks of stroke and stroke subtypes: A prospective cohort study.

EClinicalMedicine 2021 Mar 18;33:100791. Epub 2021 Mar 18.

School of Public Health, Tianjin Medical University, Tianjin, China.

Background: Although many cardiovascular risk factors for stroke have been reported before, it has not been investigated comprehensively for all major stroke types in large datasets. This study aimed to evaluate the associations of healthy behaviors, biological phenotypes and cardiovascular health (CVH) with long-term risks of strokes events, overall and stroke subtypes (ischemic stroke [IS], intracerebral hemorrhage [ICH], subarachnoid hemorrhage [SAH], and unspecified stroke).

Methods: Between 2006 and 2010, a total of 354,976 participants (age 40-70 years) in the UK Biobank free of stroke and coronary heart disease were examined and thereafter followed up to 2020. Read More

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Potential Neurologic Manifestations of COVID-19.

Neurol Clin Pract 2021 Apr;11(2):e135-e146

Department of Neurology (ASN, KTF, JZW, KTT, AKB, WSV, MSVE), Vagelos College of Physicians and Surgeons, Columbia University and the New York Presbyterian Hospital; Department of Epidemiology (AKB, MSVE), Mailman School of Public Health, Columbia University, New York, NY; Division of Cardiovascular Sciences (CJS), Lydia Becker Institute of Immunology and Inflammation, University of Manchester; and Manchester Centre for Clinical Neurosciences (CJS), Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, United Kingdom.

Purpose Of Review: Neurologic complications are increasingly recognized in the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This coronavirus is related to severe acute respiratory syndrome coronavirus (SARS-CoV) and other human coronavirus-related illnesses that are associated with neurologic symptoms. Read More

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Mesenchymal Stem Cells Transplantation in Intracerebral Hemorrhage: Application and Challenges.

Front Cell Neurosci 2021 24;15:653367. Epub 2021 Mar 24.

Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, China.

Intracerebral hemorrhage (ICH) is one of the leading causes of death and long-term disability worldwide. Mesenchymal stem cell (MSC) therapies have demonstrated improved outcomes for treating ICH-induced neuronal defects, and the neural network reconstruction and neurological function recovery were enhanced in rodent ICH models through the mechanisms of neurogenesis, angiogenesis, anti-inflammation, and anti-apoptosis. However, many key issues associated with the survival, differentiation, and safety of grafted MSCs after ICH remain to be resolved, which hinder the clinical translation of MSC therapy. Read More

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Long-Term Outcome After Decompressive Craniectomy in a Developing Country.

Acta Neurochir Suppl 2021 ;131:87-90

B.R.A.I.N., Division of Neurology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Background: Decompressive craniectomy (DC) may reduce mortality but might increase the number of survivors in a vegetative state. In this study, we assessed the long-term functional outcome of patients undergoing DC in a middle-income country.

Methods: This was a prospective observational study of patients undergoing DC at a single tertiary hospital in southern Brazil between January 2015 and December 2018. Read More

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January 2021

Wrist-hand extension function recovery in spastic hemiplegia patient by botulinum toxin injection plus surface electromyography biofeedback therapy: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25252

Department of Rehabilitation Medicine, People's Hospital of Longhua, Shenzhen, Affiliated Hospital of Guangdong Medical University.

Rationale: Wrist-hand extension function rehabilitation is a vital and difficult part of hand function recovery in spastic stroke patients. Although botulinum toxin type A (BoNTA) injection plus post injection therapy was applied to the wrist-hand rehabilitation in previous reports, conclusion was inconsistent in promoting function. For this phenomenon, proper selection of patients for BoNTA injection and correct choice of post-injection intervention could be the crucial factors for the function recovery. Read More

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Neurological outcome, mental fatigue and occurrence of aneurysms more than 15 years after aneurysmal subarachnoid haemorrhage.

World Neurosurg 2021 Apr 5. Epub 2021 Apr 5.

Institute of neurosciences and Physiology, Sahlgrenska Academy, Gothenburg University, Sweden; Department of Neurosurgery, Sahlgrenska University Hospital, Gothenburg, Sweden.

Objectives: Long-term data on neurological and radiological outcome after aneurysmal subarachnoid haemorrhage (aSAH) is scarce. The aims of this study were to report neurological and radiological outcome more than 15 years after aSAH.

Patients And Methods: Patients from Western Sweden with aSAH randomized to endovascular (EVT) or microsurgical treatment (MST) from 1997 to 2001 were included. Read More

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Low vs standardized dose anticoagulation regimens for extracorporeal membrane oxygenation: A meta-analysis.

PLoS One 2021 8;16(4):e0249854. Epub 2021 Apr 8.

Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fujian, China.

Background: To compare the safety and efficacy of low-dose anticoagulation (LA) with that of standardized dose anticoagulation (SA) for patients supported with extracorporeal membrane oxygenation (ECMO).

Methods: PubMed, MEDLINE, the Cochrane Library, and Web of Science were screened for original articles. Screening was performed using predefined search terms to identify cohort studies reporting the comparison of LA with SA in patients supported with ECMO from Nov 1990 to Jun 2020. Read More

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Association of inotrope use with neurodevelopmental outcomes in infants <29 weeks gestation: a retrospective cohort study.

J Matern Fetal Neonatal Med 2021 Apr 7:1-9. Epub 2021 Apr 7.

Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Toronto, Canada.

Objective: The primary objective was to compare neurodevelopmental (ND) outcomes at 18-24 months in preterm infants <29 weeks gestational age (GA) who received versus those who did not receive inotropes in the first week of life. The secondary objective was to assess ND outcomes according to the duration of inotropic support in the first week of life (≤3 or >3 days).

Study Design: Retrospective population-based cohort study of preterm infants <29 weeks GA admitted to participating neonatal intensive care units (NICUs) of the Canadian Neonatal Network (CNN) from January 2010 to September 2011 with follow-up data available at 18-24 months. Read More

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Intracerebral haemorrhage following spine surgery: a word of caution on the use of suction drains.

Br J Neurosurg 2021 Apr 6:1-4. Epub 2021 Apr 6.

Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore, Singapore.

Intracranial haemorrhage (ICH) is a rare but devastating complication post spinal surgery. We present three cases of post spine surgery ICH that were associated with high drain outputs postoperatively. The first patient underwent C1-C6 instrumented fusion and C4-C6 decompression. Read More

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Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery.

PLoS One 2021 5;16(4):e0249591. Epub 2021 Apr 5.

University of Louisville School of Medicine, Louisville, Kentucky, United States of America.

Traumatic spinal cord injury (SCI) is a devastating neurological condition that involves both primary and secondary tissue loss. Various cytotoxic events including hypoxia, hemorrhage and blood lysis, bioenergetic failure, oxidative stress, endoplasmic reticulum (ER) stress, and neuroinflammation contribute to secondary injury. The HIF prolyl hydroxylase domain (PHD/EGLN) family of proteins are iron-dependent, oxygen-sensing enzymes that regulate the stability of hypoxia inducible factor-1α (HIF-1α) and also mediate oxidative stress caused by free iron liberated from the lysis of blood. Read More

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Anticoagulants Used in Cardiac Catheterization of Patients With Chronic Lymphocytic Leukemia: A Case Report and Overview.

Cureus 2021 Mar 1;13(3):e13633. Epub 2021 Mar 1.

Internal Medicine, Jersey Shore University Medical Center, Neptune, USA.

Percutaneous coronary intervention (PCI) is one of the most frequently performed invasive therapeutic procedures and plays a key role in the long-term survival of patients with ischemic heart disease. Over 965,000 angioplasties are performed annually in the United States alone. While the technique and equipment have undergone significant revisions and improvement, the medical community will still benefit from more data and guidance on the optimal selection of mandatory peri-operation anticoagulation in specific, high-risk populations. Read More

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Prognostic Value of Various Hemostasis Parameters and Neurophysiological Examinations in Spontaneous Intracerebral Hemorrhage: The IRONHEART Study Protocol.

Front Neurol 2021 17;12:615177. Epub 2021 Mar 17.

Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Stroke is one of the leading causes of death in all developed countries. In Hungary, more than 10,000 patients die annually due to cerebrovascular diseases according to the WHO Mortality Database. Of these patients, 10-15 % suffer non-traumatic intracerebral hemorrhage (ICH). Read More

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CLINICAL FEATURES OF GASTROINTESTINAL ULCERATIVE BLEEDING IN ELDERLY PATIENTS COMPLICATED BY CARDIO-VASCULAR PATHOLOGY.

Wiad Lek 2021 ;74(2):202-206

MEDICAL ACADEMY OF THE HEALTH MINISTRY OF UKRAINE, DNIPRO, UKRAINE.

Objective: The aim: To determine clinical and endoscopical features of gastroduodenal hemorrhages in elderly patients with concomitant cardio-vascular pathology in a way by studying, main indicators of the immune system for drawing up further tactics.

Patients And Methods: Material and methods: The study included 609 patients with ulcerative gastroduodenal bleeding, complicated by cardio-vascular system pathology in 2017-2019 years. The observed patients were distributed into the groups: I - patients, who received treatment according to the standard system of cardiovascular pathology treatment (n=541), II - "double" therapy (n=68). Read More

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Circulating AQP4 Levels in Patients with Cerebral Amyloid Angiopathy-Associated Intracerebral Hemorrhage.

J Clin Med 2021 Mar 2;10(5). Epub 2021 Mar 2.

Neurovascular Research Laboratory, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.

Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage (ICH) in elderly patients. Growing evidence suggests a potential role of aquaporin 4 (AQP4) in amyloid-beta-associated diseases, including CAA pathology. Our aim was to investigate the circulating levels of AQP4 in a cohort of patients who had suffered a lobar ICH with a clinical diagnosis of CAA. Read More

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