21,395 results match your criteria long segment

Lengthening After Nonvascularized Fibula Grafting for Large Postinfective Bone Defect: A Case Report with Long Follow-up.

JBJS Case Connect 2021 Apr 14;11(2). Epub 2021 Apr 14.

Department of Pediatric Orthopaedics, Bai Jerbai Wadia Hospital for Children, Mumbai, India.

Case: We describe a case of lengthening of the tibial regenerate after nonvascularized fibula grafting, for postinfective tibial gap nonunion in a child. A large tibial defect secondary to osteomyelitis in a 10-month-old boy was reconstructed using a 5-cm fibula autograft. Concomitant distal tibial physeal arrest led to progressive shortening. Read More

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Dynamically crosslinked polydimethylsiloxane-based polyurethanes with contact-killing antimicrobial properties as implantable alloplasts for urological reconstruction.

Acta Biomater 2021 May 9. Epub 2021 May 9.

Materials Research Centre, Indian Institute of Science, Bangalore-560012, India; Center for Biosystems Science and Engineering, Indian Institute of Science, Bangalore-560012, India. Electronic address:

A large population of patients is reported to suffer from urinary bladder-associated irreversible physiological disorders, rationalizing a continuous surge for structural and functional substitutes of urinary tissues, including ureters, bladder-wall, and urethra. The current gold standard for bladder reconstruction, an autologous gastrointestinal graft, is proven not to be an ideal substitute in the clinic. While addressing this unmet clinical need, a unique set of antimicrobial polydimethyl siloxane-modified polyurethanes (TPU/PDMS) is designed and assessed for its potential application as a urological implant. Read More

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Laparoscopic ileal ureteral replacement to preserve the natural anti-reflux system: An initial case report.

IJU Case Rep 2021 May 16;4(3):132-135. Epub 2021 Feb 16.

Department of Urology Oita University Faculty of Medicine Yufu Oita Japan.

Introduction: Ileal ureteral replacement is one of the treatment options for long ureteral strictures. Most ileal ureteral replacements anastomose the distal side of the ileal segment directly to the bladder. We have reported here an initial case of laparoscopic ileal ureteral replacement for preserving the natural anti-reflux system. Read More

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Idiopathic myelitis presenting as Brown-Séquard syndrome: two case reports and a review of the literature.

Xi Peng Liang Wang

J Med Case Rep 2021 May 12;15(1):233. Epub 2021 May 12.

Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Background: Brown-Séquard syndrome often occurs in spinal cord injury, and few myelitis patients present with Brown-Séquard syndrome.

Case Presentation: A 33-year-old Han man was admitted with neck pain plus numbness in the right limbs for 2 days and weakness in the left limbs for 1 day. Examination was significant for left limbs with grade 4 muscle power, positive left Babinski sign, diminished vibration sensation in the left limbs and decreased pain below the right clavicle dermatome. Read More

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Characteristics and recurrence of pterygium in Saudi Arabia: a single center study with a long follow-up.

BMC Ophthalmol 2021 May 11;21(1):207. Epub 2021 May 11.

Department of Ophthalmology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Background: This study described the clinical features of patients with pterygium and analyzed the recurrence rate of conjunctival autografting alone, conjunctival autografting combined with intraoperative mitomycin C, and amniotic membrane grafting.

Methods: A retrospective cohort study of primary pterygium was conducted between January 2017 and February 2020. Factors associated with pterygium severity and recurrence were analyzed by univariate analysis and logistic regression models. Read More

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Posterior Polyethylene Tethers Reduce Occurrence of Proximal Junctional Kyphosis After Multilevel Spinal Instrumentation for Adult Spinal Deformity: A Retrospective Analysis.

Neurosurgery 2021 May 10. Epub 2021 May 10.

Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia, USA.

Background: Proximal junctional kyphosis (PJK) is a common postoperative complication after adult spinal deformity (ASD) surgery and may manifest with neurological decline, worsening spinal deformity, and spinal instability, which warrant reoperation. Rates of PJK may be as high as 69.4% after ASD surgery. Read More

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The genome sequence of hairy root Rhizobium rhizogenes strain LBA9402: Bioinformatics analysis suggests the presence of a new opine system in the agropine Ri plasmid.

Microbiologyopen 2021 Mar;10(2):e1180

Institute of Biology, Leiden University, Leiden, The Netherlands.

We report here the complete genome sequence of the Rhizobium rhizogenes (formerly Agrobacterium rhizogenes) strain LBA9402 (NCPPB1855rifR), a pathogenic strain causing hairy root disease. To assemble a complete genome, we obtained short reads from Illumina sequencing and long reads from Oxford Nanopore Technology sequencing. The genome consists of a 3,958,212 bp chromosome, a 2,005,144 bp chromid (secondary chromosome) and a 252,168 bp Ri plasmid (pRi1855), respectively. Read More

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Early detection of change patterns in COVID-19 incidence and the implementation of public health policies: A multi-national study.

Public Health Pract (Oxf) 2021 Nov 10;2:100064. Epub 2020 Dec 10.

Division of Biostatistics and Data Science, Department of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, USA.

Objectives: The COVID-19 pandemic caused by the novel SARS-CoV-2 coronavirus has drastically altered the global realities. Harnessing national scale data from the COVID-19 pandemic may better inform policy makers in decision making surrounding the reopening of society. We examined country-level, daily-confirmed, COVID-19 case data from the World Health Organization (WHO) to better understand the comparative dynamics associated with the ongoing global pandemic at a national scale. Read More

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November 2021

Investigation of a method for long-term preservation of the vascular allograft.

Vascular 2021 May 9:17085381211012945. Epub 2021 May 9.

Medical School, The University of Western Australia, Crawley, WA, Australia.

Background/objective: During multiple organ procurement, blood vessels are routinely retrieved and stored in University of Wisconsin solution and then discarded after two weeks, if not used at organ transplantation owing to lack of a method for long-term preservation. Therefore, the aim of this study is to investigate a method for long-term preservation of vascular allografts in ethanol.

Methods: Aorta and vena cava allografts were retrieved and stored in 75% ethanol solution for 12 months at 4°C. Read More

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Pancreaticoduodenectomy for hepatic portal lymph node metastasis after hepatic resection for hepatocellular carcinoma: A clinical case report.

Int J Surg Case Rep 2021 Apr 27;82:105921. Epub 2021 Apr 27.

Center for Pathology and Cytology, Bach Mai Hospital, Viet Nam.

Introduction: In 2018, Hepatocellular carcinoma (HCC) was predicted to be the sixth most commonly diagnosed cancer. Extra-hepatic metastasis due to HCC is a poor prognostic factor, depending on the stage of the disease.

Presentation Of Case: We report a case of a 52-years old male who had undergone Segment 5 (S5) hepatectomy for HCC of 4. Read More

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ADIPOR1 deficiency-induced suppression of retinal ELOVL2 and docosahexaenoic acid levels during photoreceptor degeneration and visual loss.

Cell Death Dis 2021 May 7;12(5):458. Epub 2021 May 7.

Laboratory of Retinal Cell Biology, Tokyo, Japan.

Lipid metabolism-related gene mutations can cause retinitis pigmentosa, a currently untreatable blinding disease resulting from progressive neurodegeneration of the retina. Here, we demonstrated the influence of adiponectin receptor 1 (ADIPOR1) deficiency in retinal neurodegeneration using Adipor1 knockout (KO) mice. Adipor1 mRNA was observed to be expressed in photoreceptors, predominately within the photoreceptor inner segment (PIS), and increased after birth during the development of the photoreceptor outer segments (POSs) where photons are received by the visual pigment, rhodopsin. Read More

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Predictors of no-reflow phenomenon following percutaneous coronary intervention for ST-segment elevation myocardial infarction.

Ann Cardiol Angeiol (Paris) 2021 May 4. Epub 2021 May 4.

ABVIMS and Dr RML Hospital, New Delhi, India. Electronic address:

Objectives: No reflow during percutaneous coronary intervention (PCI) is a complex issue with serious outcomes. Multiple studies have studied predictors of no-reflow during primary PCI, but data on patients with the late presentation is sparse, which constitutes the majority of patients in peripheral centers. This study aimed to determine predictors of no-reflow during PCI in patients with ST-segment elevation myocardial infarction (STEMI) in 7 days. Read More

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[Intestinal and appendicular ureteral substitution].

Urologiia 2021 May(2):14-20

Department of Urology of FGBOU VO North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia.

Aim: To present the technical features and results of intestinal and appendicular ureteral replacement.

Material And Methods: From 1998 to 2020, a total of 196 patients aged 18 to 77 years (mean age 49.5 +/- 1. Read More

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Short-Term Anterior Segment Changes After Nd-YAG Laser Posterior Capsulotomy in Pseudophakic Eyes with Fuchs' Endothelial Dystrophy.

Clin Ophthalmol 2021 30;15:1819-1825. Epub 2021 Apr 30.

Department of Ophthalmology, Faculty of Medicine, Benha University, Benha, Egypt.

Purpose: To describe the changes in the central corneal thickness (CCT), endothelial cell count (ECC), intraocular lens (IOL) position, and refractive error 1 and 3 months after Nd-YAG laser posterior capsulotomy (YAG-PC) for posterior capsular opacification (PCO) in pseudophakic eyes with Fuchs' endothelial cell dystrophy (FECD).

Design: Prospective case-control.

Participants: Fifty pseudophakic eyes of 50 patients with visually significant PCO (25 with healthy corneas, and 25 with FECD grade 1 and 2). Read More

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Long-Term Prognostic Outcomes and Implication of Oral Anticoagulants in Patients with New-Onset Atrial Fibrillation following ST-Segment Elevation Myocardial Infarction.

Am Heart J 2021 May 3. Epub 2021 May 3.

Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Background: New-onset atrial fibrillation (NEW-AF) following ST-segment elevation myocardial infarction (STEMI) is a common complication, but the long-term mortality and morbidity remains unknown the true prognostic impact of NEW-AF is unknown. Additionally, the optimal treatment of NEW-AF among patients with STEMI is warranted.

Methods: A large cohort of consecutive patients with STEMI treated with percutaneous coronary intervention were identified using the Eastern Danish Heart Registry from 1999-2016. Read More

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A Case of Implantable Collamer Lens (ICL) with Reverse Orientation for 10 Years.

Case Rep Ophthalmol Med 2021 14;2021:6641475. Epub 2021 Apr 14.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Background: Implantable collamer lens (ICL) might rarely cause complications that warrant explantation. Here, we presented a case of inverted ICL that has undergone explantation after a 10-year duration. . Read More

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Diabetic Retinopathy Detection Using Local Extrema Quantized Haralick Features with Long Short-Term Memory Network.

Int J Biomed Imaging 2021 14;2021:6618666. Epub 2021 Apr 14.

Department of Computer Engineering, Tishk International University, Erbil, KRD, Iraq.

Diabetic retinopathy is one of the leading diseases affecting eyes. Lack of early detection and treatment can lead to total blindness of the diseased eyes. Recently, numerous researchers have attempted producing automatic diabetic retinopathy detection techniques to supplement diagnosis and early treatment of diabetic retinopathy symptoms. Read More

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Descending Thoracic Aorta Stenosis Treated by Percutaneous Transluminal Angioplasty and Stenting with Coaxial Sheath Introduction Technique in a Small Child.

Int Med Case Rep J 2021 28;14:265-270. Epub 2021 Apr 28.

Department of Emergency and Interventional Cardiology, Hue Central Hospital, Hue City, Vietnam.

A 10-year-old girl (23 kg) having a medical history of uncontrolled hypertension was presented to our hospital because of acute left heart failure. Transthoracic echocardiography showed stenosis of descending thoracic aorta with a maximum trans-stenotic pressure gradient of 50 mmHg and severe left ventricular systolic dysfunction with an ejection fraction of 20%. She was diagnosed with Takayasu arteritis with a long severe stenosis of segment III of the thoracic aorta. Read More

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Non-operative management of biliary complications after Liver Transplantation in pediatric patients: A 30-year experience.

Pediatr Transplant 2021 May 5:e14028. Epub 2021 May 5.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.

Background: To evaluate the efficacy of percutaneous and endoscopic therapeutic interventions for biliary strictures and leaks following LT in children.

Methods: Retrospective analysis of 49 consecutive pediatric liver transplant recipients (27 girls, 22 boys, mean age at transplant 3.9 years) treated at our institution from 1989 to 2019 for biliary leak and/or biliary stricture was performed. Read More

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Tracheal In Vitro Reconstruction Using a Decellularized Bio-Scaffold in Combination with a Rotating Bioreactor.

Methods Mol Biol 2021 May 6. Epub 2021 May 6.

Laboratory of Biomedical Embryology, Department of Health, Animal Science and Food Safety and Center for Stem Cell Research, Università degli Studi di Milano, Milan, Italy.

Long-segment airway stenosis as well as their neoplastic transformation is life-threatening and still currently represent unsolved clinical problems. Indeed, despite several attempts, definitive surgical procedures are not presently available, and a suitable tracheal reconstruction or replacement remains an urgent clinical need. A possible innovative strategic solution to restore upper airway function may be represented by the creation of a bioprosthetic trachea, obtained through the combination of tissue engineering and regenerative medicine. Read More

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Pseudarthrosis in adult spine deformity surgery: risk factors and treatment options.

Eur Spine J 2021 May 5. Epub 2021 May 5.

Bordeaux University Hospital, Department of Spinal Surgery Unit 1, C.H.U Tripode Pellegrin, Université de Bordeaux, Place Amélie Raba Léon, 33076, Bordeaux, France.

Purpose: Highlight risk factors for pseudarthrosis in long-segment spinal fusions, collect the approaches carried to address this complication.

Methods: Patients with ASD and fusion of ≥ 4 levels with minimum follow-up (FU) of ≥ 2 years were included. Full-body X-rays were done preoperatively, < 3 months and ≥ 2 years. Read More

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Longitudinal phenotypic study of late-onset retinal degeneration due to a founder variant c.562C>A p.(Pro188Thr) in the gene.

Ophthalmic Genet 2021 May 5:1-12. Epub 2021 May 5.

Department of Ophthalmology, Ghent University Hospital, Ghent, Belgium.

: Late-onset retinal degeneration (L-ORD) is a rare autosomal dominant retinal dystrophy related to gene variants.: Twenty-six patients (21-81 years) with L-ORD due to c.562C>A p. Read More

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Pathological axis fracture secondary to a solitary bone plasmacytoma: Two cases and a literature review.

Surg Neurol Int 2021 14;12:165. Epub 2021 Apr 14.

Spine unit, Department of Orthopedic and Traumatology, Clínica Alemana, Santiago, Chile.

Background: Solitay bone plasmocytoma (SBP) account for just 5-10% of all plasma cell neoplasms. They are infrequent in the cervical spine, especially involving the C0-C2 segment. In this article we conducted a literature review and present the diagnosis, management and long term course of two patients with SBP of C2 causing cervical instability. Read More

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Efficacy of montelukast in preventing seasonal recurrence of vernal keratoconjunctivitis in children.

Eye (Lond) 2021 May 4. Epub 2021 May 4.

Cornea and Anterior Segment Services, MTC Campus, LV Prasad Eye Institute, Bhubaneswar, India.

Background: Vernal keratoconjunctivitis is a chronic, seasonally exacerbated, allergic inflammation of the eye. The study aims to evaluate the efficacy and safety of oral montelukast in treating vernal keratoconjunctivitis in pediatric patients.

Methods: This is a 26-week, prospective, randomized, open-label study. Read More

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Bacterial Outer Membrane Proteins Are Targeted to the Bam Complex by Two Parallel Mechanisms.

mBio 2021 05 4;12(3). Epub 2021 May 4.

Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA

Membrane proteins that are integrated into the outer membrane of Gram-negative bacteria typically contain a unique "β barrel" structure that serves as a membrane spanning segment. A conserved "β signal" motif is located at the C terminus of the β barrel of many outer membrane proteins (OMPs), but the function of this sequence is unclear. We found that mutations in the β signal slightly delayed the assembly of three model OMPs by reducing their affinity for the arrel ssembly achinery (Bam) complex, a heterooligomer that catalyzes β barrel insertion, and led to the degradation of a fraction of the protein in the periplasm. Read More

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Metal-On-Metal versus Metal-On-Plastic Artificial Discs in Two-Level Anterior Cervical Disc Replacement: A Meta-Analysis with Follow-Up of 5 Years or More.

Spine J 2021 Apr 30. Epub 2021 Apr 30.

St. Joseph's University Medical Center, Department of Orthopaedic Surgery, 703 Main Street, Paterson, NJ 07503. Electronic address:

Background Context: Although highlighted in joint arthroplasty studies, long-term outcomes between differing biomaterial composites, such as metal-on-metal (MoM) and metal-on-plastic (MoP) in anterior cervical disc replacement (ACDR) have not been thoroughly investigated.

Purpose: The purpose of this study was to evaluate the patient-reported clinical outcomes, overall reoperation rates, complications, and rates of ASD of MoM versus MoP artificial discs in two-level ACDR for the treatment of cervical DDD.

Study Design/setting: Meta-analysis and systematic review PATIENT SAMPLE: 980 patients (442 MoM, 538 MoP) across 7 studies OUTCOME MEASURES: Patient reported clinical outcomes (NDI, VAS-n, VAS-a), overall reoperation rates, complications and rates of ASD METHODS: A systematic search strategy of three electronic databases (PubMed, CINAHL Plus, and SCOPUS) was conducted utilizing terms related to two-level ACDR. Read More

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Factors associated with temporary pacing insertion in patients with inferior ST-segment elevation myocardial infarction.

PLoS One 2021 3;16(5):e0251124. Epub 2021 May 3.

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Shimotsuke, Japan.

Background: High-degree atrioventricular block (HAVB) is a prognostic factor for survival in patients with inferior ST-segment elevation myocardial infarction (STEMI). However, there is little information about factors associated with temporary pacing (TP). The aim of this study was to find factors associated with TP in patients with inferior STEMI. Read More

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Automated Analysis of Alignment in Long-Leg Radiographs by Using a Fully Automated Support System Based on Artificial Intelligence.

Radiol Artif Intell 2021 Mar 23;3(2):e200198. Epub 2020 Dec 23.

Department of Diagnostic and Interventional Radiology, University Hospital Düsseldorf, Düsseldorf, Germany (J.S., D.B.A., S.N.); Institute of Computer Vision and Imaging, RWTH University Aachen, Pauwelsstrasse 30, 52072 Aachen, Germany (J.S., D.M.); Department of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany (D.T., M.P., F.M., C.K., S.N.); and Faculty of Mathematics and Natural Sciences, Institute of Informatics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany (S.C.).

Purpose: To develop and validate a deep learning-based method for automatic quantitative analysis of lower-extremity alignment.

Materials And Methods: In this retrospective study, bilateral long-leg radiographs (LLRs) from 255 patients that were obtained between January and September of 2018 were included. For training data ( = 109), a U-Net convolutional neural network was trained to segment the femur and tibia versus manual segmentation. Read More

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Quantifying the Spatiotemporal Influence of Acute Myocardial Ischemia on Volumetric Conduction Speeds.

Comput Cardiol (2010) 2020 Sep 10;47. Epub 2021 Feb 10.

Scientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.

Acute myocardial ischemia compromises the ordered electrical activation of the heart, however, because of sampling limitations, volumetric changes in activation have not been measured. We used a large-animal experimental model and high-resolution volumetric mapping to study the effects of ischemia on conduction speeds (CS) throughout the myocardium. We estimated CS and electrocardiographic changes (ST segments) and evaluated the spatial and temporal correlations between them across 11 controlled episodes. Read More

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September 2020

Longitudinal changes on liver proton density fat fraction differ between liver segments.

Quant Imaging Med Surg 2021 May;11(5):1701-1709

Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.

Background: To study the spatial heterogeneity of liver fat fraction changes during a long-term lifestyle intervention study using magnetic resonance imaging (MRI).

Methods: Thirty-two subjects underwent two MRI-scans in a span of one year. A chemical shift encoding-based water-fat separation method was applied to measure liver proton density fat fraction (PDFF) maps. Read More

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