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The Evaluation of the Containment Efficacy of Semi-Rigid Isolators for Housing Cages of Laboratory Animals Infected With BSL-3 Agents.

ILAR J 2021 Jun 23. Epub 2021 Jun 23.

Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Research animals models infected with Biosafety Level-3 (BSL-3) agents need to be housed in specialized biocontainment caging. Most of these specialized cages have input and exhaust that is high efficiency particulate air filtered and sealed to prevent escape of the BSL-3 agent. An alternative to the use of the above BSL-3 biocontainment caging is the use of a flexible film or modified semi-rigid plastic film isolator that has its own high efficiency particulate air-filtered input and exhaust and is sealed with respect to the animal room environment, thus preventing BSL-3 agent escape. Read More

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First report of root rot of Polygonatum odoratum caused by Fusarium acuminatum in China.

Plant Dis 2021 Jun 23. Epub 2021 Jun 23.

Liaoning Research Institute of Cash Crops, Liaoyang, Liaoning, China.

Polygonatum odoratum (Mill.) Druce is used in traditional Chinese medicine and also consumed as a vegetable. In July of 2020, a root rot was observed on P. Read More

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A novel strain-specific neutralizing epitope on glycoprotein H of Human Cytomegalovirus.

J Virol 2021 Jun 23:JVI0065721. Epub 2021 Jun 23.

Friedrich-Alexander Universität Erlangen-Nürnberg, Institut für klinische und molekulare Virologie, Erlangen, Germany.

Human cytomegalovirus (HCMV) is a ubiquitous pathogen that causes severe clinical disease in immunosuppressed patients and congenitally infected newborn infants. Viral envelope glycoproteins represent attractive targets for vaccination or passive immunotherapy. To extend the knowledge of mechanisms of virus neutralization, monoclonal antibodies (MAbs) were generated following immunization of mice with HCMV virions. Read More

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MINERALIZATION OF TEETH ENAMEL AFTER ERUPTION.

Wiad Lek 2021 ;74(6):1297-1301

POLTAVA STATE MEDICAL UNIVERSITY, POLTAVA, UKRAINE.

Objective: The aim: The paper was aimed at the study of the processes of mineralization of the enamel of the permanent tooth after its eruption.

Patients And Methods: Materials and methods: To study the structure of the enamel of permanent teeth has been carried out using light and electron microscopy. The study of the process of the development of the primordia of the permanent teeth involved 10 culled puppies of 30-40 days of age. Read More

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January 2021

Movement patterns of temperate wrasses (Labridae) within a small Marine Protected Area.

J Fish Biol 2021 Jun 22. Epub 2021 Jun 22.

Ecosystem Acoustics Group, Institute of Marine Research, Austevoll Research Station, Storebø, Norway.

The movement patterns of three commercially important wrasse (Labridae) species inside a small marine protected area (~ 0.15 km ) on the west coast of Norway were analysed over a period of 21 months. The mean distance between capture and recapture locations varied between 10-187 meters and was species and season specific. Read More

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Economic valuation of ecosystem services: application of a choice experiment approach on mount Guna services, North West of Ethiopia.

Heliyon 2021 Jun 31;7(6):e07164. Epub 2021 May 31.

School of Economics, University of Gondar, Gondar, Ethiopia.

Guna Mountain is the highest point with an elevation of 4,113 m above sea level and located in South Gondar Zone. It is surrounded by Estie, Lay Gayint, Begemidir Guna, and Farta Woredas and served as a source of livelihood for the nearby communities. However, the area of Mount Guna has been still unprotected because of a lack of suitable conservation measures and weak control of inappropriate practices. Read More

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Cross-sectional study on intestinal parasite infections in different ecological zones of the Department of La Paz, Bolivia.

One Health 2021 Dec 27;13:100271. Epub 2021 May 27.

Dipartimento di Sanità Pubblica e Malattie Infettive, Università di Roma Sapienza, Roma, Italy.

We performed a cross-sectional parasitological survey to assess the prevalence of protozoa and helminth infection among 275 school-age children (SAC) living in rural and peri-urban areas located in different ecological zones of the Department of La Paz, Bolivia. Public health activities for the control of STH, based on the biannual administration of mebendazole to preschool and school children are implemented at national level since 1986. We found an overall prevalence of 82. Read More

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December 2021

Uretero-arterial fistula: Six new cases and systematic review of the literature.

Prog Urol 2021 Jun 19. Epub 2021 Jun 19.

Urology department, University Hospital Caen, Caen, France. Electronic address:

Aim: Secondary uretero-arterial fistulas (SUAF) are uncommon, underrated and threatening for any patient. Gross hematuria is a clinical symptom of this pathology for patients with history of pelvic radiotherapy, complex pelvic surgery or long-term ureteral stenting. The purpose of this work is to assess risk factors, diagnosis and treatment of SUAF. Read More

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Effects of GnRH and hCG administration during early luteal phase on estrous cycle length, expression of estrus and fertility in lactating dairy cows.

Theriogenology 2021 Jun 16;173:23-31. Epub 2021 Jun 16.

Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Wisconsin, 53706, USA. Electronic address:

Our objective was to determine the effects of a single treatment of human chorionic gonadotropin (hCG) or GnRH from d 5 to 7 of the estrous cycle on cycle length, expression of estrus and fertility in lactating dairy cows. Lactating Holstein cows (n = 354) located in Farm 1 and lactating Jersey cows located in Farm 2 (n = 210) detected in estrus by an Automated Activity Monitor (AAM) system from 27 to 50 days in milk (DIM) were randomly assigned to receive one of three treatments from d 5 to 7 of the estrous cycle: control (untreated; CON; Holstein, n = 111; Jersey, n = 66), GnRH (86 μg gonadorelin acetate im; Holstein, n = 116; Jersey, n = 75), or hCG (3,300 IU im; Holstein, n = 127; Jersey, n = 69). Ovaries were scanned with ultrasound in a random subgroup of cows (Holstein/Farm 1, n = 147; Jersey/Farm 2, n = 94) on the day of treatment and 3 or 4 d later to determine ovulation. Read More

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Fluorinated Poly-oxalate Electrolytes Stabilizing both Anode and Cathode Interfaces for All-Solid-State Li/NMC811 Batteries.

Angew Chem Int Ed Engl 2021 Jun 22. Epub 2021 Jun 22.

Beijing University of Chemical Technology, Department of chemical engineering, CHINA.

The relatively narrow electrochemical steady window and low ionic conductivity are two critical challenges for Li+ conducting solid-polymer-electrolytes(SPE). Here, a family of poly-oxalate(POE) structures were prepared as SPE; among them, the odd-carbon-diols composed POEs show higher ionic conductivity than even-carbon-diols composed POEs, and the propanediol-composed POE(C5-POE) owns the highest Li+ conductivity. The HOMO (Highest Occupied Molecular Orbital) electrons of POE were found located on the terminal units. Read More

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Taxonomic and functional homogenization of farmland birds along an urbanization gradient in a tropical megacity.

Glob Chang Biol 2021 Jun 22. Epub 2021 Jun 22.

Institute of Agricultural Sciences in the Tropics, Department of Ecology of Tropical Agricultural Systems, University of Hohenheim, 70599, Stuttgart, Germany.

Urbanization is a major driver of land use change and biodiversity decline. While most of the ongoing and future urbanization hot spots are located in the Global South, the impact of urban expansion on agricultural biodiversity and associated functions and services in these regions has widely been neglected. Additionally, most studies assess biodiversity responses at local scale (α-diversity), however, ecosystem functioning is strongly determined by compositional and functional turnover of communities (β-diversity) at regional scales. Read More

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3D-Positioning of Nanoparticles in High-Curvature Block Copolymer Domains.

Angew Chem Int Ed Engl 2021 Jun 22. Epub 2021 Jun 22.

Jülich Centre for Neutron Science (JCNS-1/IBI-8), Forschungszentrum Jülich, 52425, Jülich, Germany.

The defined assembly of nanoparticles in polymer matrices is an important precondition for next-generation functional materials. Here we demonstrate that a defined three-dimensional nanoparticle assembly within the unit cells can be realized by directly linking the nanoparticles to block copolymers. We show that for a range of nearly symmetric to unsymmetric block copolymers there are only two formed structures, a hexagonal lattice of P6/mmm-symmetry, where the nanoparticles are located in 1D-arrays within the cylindrical domains, and a cubic lattice of Im3m-symmetry, where the nanoparticles are located in the octahedral voids of a BCC-lattice, corresponding to the structure of ferrite steel. Read More

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Genetic variation in catechol-O-methyltransferase is associated with individual differences in conditioned pain modulation in healthy subjects.

J Gene Med 2021 Jun 22:e3374. Epub 2021 Jun 22.

Department of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ, USA.

Background: Genetic variation in the catechol-O-methyltransferase (COMT) gene is associated with sensitivity to both acute experimental pain and chronic pain conditions. Four single nucleotide polymorphisms (SNPs) have traditionally been used to infer three common haplotypes designated as low, average and high pain sensitivity (LPS, APS and HPS) and are reported to affect both COMT enzymatic activity and pain sensitivity. One mechanism that may partly explain individual differences in sensitivity to pain is Conditioned Pain Modulation (CPM). Read More

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YAP1-TFE3 Gene Fusion Variant in Clear Cell Stromal Tumor of Lung: Report of Two Cases in Support of a Distinct Entity.

Histopathology 2021 Jun 22. Epub 2021 Jun 22.

Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Ohio, USA.

Aims: Clear cell (hemangioblastoma-like) stromal tumor of the lung is a newly described, rare pulmonary neoplasm. Recurrent YAP1-TFE3 gene fusions have recently been reported in three cases. We describe two additional cases and confirm the characteristic YAP1-TFE3 gene fusion. Read More

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First Report of Sea buckthorn Stem Wilt Caused by Fusarium sporotrichioides in Gansu, China.

Plant Dis 2021 Jun 22. Epub 2021 Jun 22.

Shenyang Agricultural University, 98428, College of Plant Protection, Shenyang, China;

Sea buckthorn (Hippophae rhamnoides) is an important deciduous shrub for fruit and ecological restoration in arid and semi-arid regions of China. Twelve Chinese and Russian cultivars (cv. Shenqiuhong, eshi01, . Read More

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First report of damping off disease caused by Fusarium oxysporum on Pinus pinea in Jordan.

Plant Dis 2021 Jun 22. Epub 2021 Jun 22.

The University of Jordan, Plant Protection, Queen Rania St, Amman, Jordan, 11942;

Forests of Jordan are located in the northern and southern parts of the country with 60% and 40%, respectively. Natural forests constitute about 75% in the northern part and 25% in the southern part. There are many types of forest trees in Jordan including pines (Pinus spp. Read More

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Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema.

Clin Exp Allergy 2021 Jun 22. Epub 2021 Jun 22.

Université de Paris, UMRS 1124, INSERM, Paris, France.

Background: Numerous genes have been associated with the three most common allergic diseases (asthma, allergic rhinitis or eczema) but these genes explain only a part of the heritability. In the vast majority of genetic studies, complex phenotypes such as co-morbidity of two of these diseases, have not been considered. This may partly explain missing heritability. Read More

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Promoting Equity, Diversity and Social Justice Through Faculty-Led Transformative Projects.

Innov High Educ 2021 Jun 17:1-22. Epub 2021 Jun 17.

Counseling Psychology, Department of Educational Studies, College of Education, Purdue University, West Lafayette, IN USA.

We present a transformative professional development project with a focus on equity, diversity and social justice (EDSJ) to raise cultural awareness among faculty, increase agency, and promote positive change through transformative projects. Twenty-three faculty members from nine different colleges located at a Research I university were provided with critical cultural awareness workshops and then supported to develop transformative projects related to EDSJ. Based on focus group interviews and pre-post surveys, we identified four themes and five categories: two outcome-related ( and and two operational themes ( and We conclude that faculty-centered and transformative professional development projects could significantly benefit all those interested in establishing a culturally inclusive, positive and responsive climate. Read More

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Tsunami detection by GPS-derived ionospheric total electron content.

Sci Rep 2021 Jun 21;11(1):12978. Epub 2021 Jun 21.

National Research Center for Integrated Natural Disaster Management, Santiago, Chile.

To unravel the relationship between earthquake and tsunami using ionospheric total electron content (TEC) changes, we analyzed two Chilean tsunamigenic subduction earthquakes: the 2014 Pisagua M 8.1 and the 2015 Illapel M 8.3. Read More

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Miniaturized tri-notched wideband bandpass filter with ultrawide upper stopband suppression.

Sci Rep 2021 Jun 21;11(1):13004. Epub 2021 Jun 21.

Department of Communication Engineering, Xi'an Shiyou University, Xi'an, 710065, People's Republic of China.

Stepped impedance resonator (SIR) and its derivative resonators are widely used in the design of microwave filters. However, many spurious modes will be introduced into the stopband, resulting in lower upper stopband suppression and performance degradation. Based on the principle of slit line, a method to enhance the upper stopband suppression is proposed and verified by a miniaturized tri-notched wideband bandpass filter based on stub loaded ring resonator (SLRR) and shorted-stub loaded SIR (SSLSIR). Read More

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Sero-molecular epidemiology of hepatitis E virus in pigs and human contacts in Ghana.

One Health Outlook 2021 Jun 22;3(1):13. Epub 2021 Jun 22.

Institute of Virology, Charite, Berlin, Germany.

Background: Hepatitis E virus (HEV) is among the leading causes of viral hepatitis in most developing countries. Zoonotic acquisition of HEV genotype 3 from swine has come into focus more recently. Available studies on HEV in Ghana and other countries in the region do not provide enough information towards understanding the epidemiology of HEV in human and animal populations. Read More

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Modularity and granularity across the language network-A primary progressive aphasia perspective.

Cortex 2021 May 24;141:482-496. Epub 2021 May 24.

Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; Northwestern University Feinberg School of Medicine, Department of Psychiatry and Behavioral Sciences, Chicago, IL, USA.

Tests of grammar, repetition and semantics were administered to 62 prospectively enrolled right-handed participants with primary progressive aphasia (PPA). Structural brain images were obtained at the time of testing. Regression analyses uncovered 3 clearly delineated non-overlapping left hemisphere clusters where cortical thinning (atrophy) was significantly correlated with impaired performance. Read More

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Stress distribution and displacement of three different types of micro-implant assisted rapid maxillary expansion (MARME): a three-dimensional finite element study.

Prog Orthod 2021 Jun 21;22(1):20. Epub 2021 Jun 21.

Technology Research Center, University of Mogi das Cruzes, Dr. Cândido Xavier de Almeida Souza Avenue, 200, Mogi das Cruzes, 08780-91, São Paulo, Brazil.

Background/objective: Until 2010, adults underwent surgical treatment for maxillary expansion; however, with the advent of micro-implant-assisted rapid maxillary expansion (MARME), the availability of less invasive treatment options has increased. Nevertheless, individuals with severe transverse maxillary deficiency do not benefit from this therapy. This has aroused interest in creating a new device that allows the benefit of maxillary expansion for these individuals. Read More

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Structural variability and dynamics in the ectodomain of an ancestral-type classical cadherin revealed by AFM imaging.

J Cell Sci 2021 Jun 21. Epub 2021 Jun 21.

Laboratory of Evolutionary Cell and Developmental Biology, JT Biohistory Research Hall, 1-1 Murasaki-cho, Takatsuki, Osaka, 569-1125, Japan.

Type III cadherin represents the ancestral form of classical cadherin in bilaterian metazoans. Drosophila possesses type III and type IVa cadherins, known as DN- and DE-cadherins, respectively. Mature DN- and DE-cadherins have 15 and 7 extracellular cadherin domain (EC) repeats, respectively, with DN-cadherin EC6-11 homologous to DE-cadherin EC1-6. Read More

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Frequencies and Variations of Magnaporthe oryzae Avirulence Genes in Hunan Province, China.

Plant Dis 2021 Jun 21. Epub 2021 Jun 21.

Hunan Hybrid Rice Research Center, State Key Laboratory of Hybrid Rice, No.736, Yuanda 2 Road, Furong district, Changsa, Hunan, China, 410125;

Rice blast caused by Magnaporthe oryzae poses significant threaten to rice production. For breeding and deploying resistant rice varieties, it is essential to understand the frequencies and genetic variations of avirulence (AVR) genes in the pathogen populations. In this study, 444 isolates were collected from Hunan Province, China in 2012, 2015, and 2016, and their pathogenicity was evaluated by testing them on monogenic rice lines carrying resistance (R) genes Pita, Pizt, Pikm, Pib, or Pi9. Read More

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Construction of an evacuee placement model for tsunami shelters considering physical distancing to prevent COVID-19 infection.

Prog Disaster Sci 2021 Oct 16;11:100183. Epub 2021 Jun 16.

Susaki Regional Welfare and Health Center, Kochi, Japan.

Earthquakes and tsunamis are expected to occur within the next 30 years along Japan's Nankai Trough. Existing disaster prevention plans and calculated evacuation capacities in the coastal areas that would be affected do not account for physical distancing in the context of COVID-19. Therefore, we developed a tsunami evacuation placement model incorporating physical distance guidelines for infection control and living space per person into calculations of evacuation center accommodation capacities in Aki City, Kochi Prefecture. Read More

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October 2021

No evidence for genetic sex determination in .

R Soc Open Sci 2021 Jun 16;8(6):202292. Epub 2021 Jun 16.

Department of Environmental Sciences, Zoology, University of Basel, 4051, Basel, Switzerland.

Mechanisms of sex determination (SD) differ widely across the tree of life. In genotypic sex determination (GSD), genetic elements determine whether individuals are male or female, while in environmental sex determination (ESD), external cues control the sex of the offspring. In cyclical parthenogens, females produce mostly asexual daughters, but environmental stimuli such as crowding, temperature or photoperiod may cause them to produce sons. Read More

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The contribution of cooking appliances and residential traffic proximity to aerosol personal exposure.

J Environ Health Sci Eng 2021 Jun 22;19(1):307-318. Epub 2021 Jan 22.

School of Geography, Earth and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT UK.

Purpose: Indoor and outdoor factors affect personal exposure to air pollutants. Type of cooking appliance (i.e. Read More

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Association of Polymorphisms in T-Cell Activation Costimulatory/Inhibitory Signal Genes With Allograft Kidney Rejection Risk.

Front Immunol 2021 2;12:650979. Epub 2021 Jun 2.

Nephrology Department Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, IdISSC, Madrid, Spain.

The genes , and conform the costimulatory (CD28-CD86) or inhibitory (CTLA-4-CD86) signal in T-cell activation. T-cell immune response has a critical role in allograft rejection, and single nucleotide polymorphisms (SNPs) located in these genes have been widely analyzed with controversial results. We analyzed a group of SNPs located in the three genes: : rs3116496; : rs1129055; and : rs231775 and rs3087243 in a cohort of 632 consecutively recruited kidney transplanted subjects. Read More

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Classification of Schizophrenia by Combination of Brain Effective and Functional Connectivity.

Front Neurosci 2021 3;15:651439. Epub 2021 Jun 3.

School of Medical Engineering, Xinxiang Medical University, Xinxiang, China.

At present, lots of studies have tried to apply machine learning to different electroencephalography (EEG) measures for diagnosing schizophrenia (SZ) patients. However, most EEG measures previously used are either a univariate measure or a single type of brain connectivity, which may not fully capture the abnormal brain changes of SZ patients. In this paper, event-related potentials were collected from 45 SZ patients and 30 healthy controls (HCs) during a learning task, and then a combination of partial directed coherence (PDC) effective and phase lag index (PLI) functional connectivity were used as features to train a support vector machine classifier with leave-one-out cross-validation for classification of SZ from HCs. Read More

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