Cell Death Dis 2014 Mar 6;5:e1106. Epub 2014 Mar 6.
1] Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan  Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan  Infectious Disease and Signaling Research Center, National Cheng Kung University, Tainan, Taiwan  Institute for Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
The chromosomal passenger complex (CPC) plays a pivotal role in controlling accurate chromosome segregation and cytokinesis during cell division. Aurora-B, one of the chromosomal passenger proteins, is important for the mitotic spindle assembly checkpoint (SAC). Previous reports noted that Aurora-C is predominantly expressed in male germ cells and has the same subcellular localization as Aurora-B. Read More