13,421 results match your criteria lobe lesions

Xylological Variant of Reverse Fregoli Syndrome, Delusions of Being a Tree.

CNS Spectr 2021 Apr;26(2):145

Smell and Taste Treatment and Research Foundation, Chicago, IL, USA.

Introduction: The delusion of being a living animate non-animal object has not heretofore been reported.

Methods: A 21-year-old right-handed cisgender female, two months prior to presentation, noted stiffness and difficulty with ambulation. One-month prior to admission, she experienced recurrent depression with myriad vegetative and nonvegetative symptoms of depression. Read More

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Pre-stroke cognitive impairment is associated with vascular imaging pathology: a prospective observational study.

BMC Geriatr 2021 Jun 14;21(1):362. Epub 2021 Jun 14.

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Background: Chronic brain pathology and pre-stroke cognitive impairment (PCI) is predictive of post-stroke dementia. The aim of the current study was to measure pre-stroke neurodegenerative and vascular disease burden found on brain MRI and to assess the association between pre-stroke imaging pathology and PCI, whilst also looking for potential sex differences.

Methods: This prospective brain MRI cohort is part of the multicentre Norwegian cognitive impairment after stroke (Nor-COAST) study. Read More

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Exploration of spatial distribution of brain metastasis from small cell lung cancer and identification of metastatic risk level of brain regions: a multicenter, retrospective study.

Cancer Imaging 2021 Jun 13;21(1):41. Epub 2021 Jun 13.

Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 88 Keling Road, Suzhou New District, Suzhou, 215163, Jiangsu, China.

Objectives: This study aimed to explore the spatial distribution of brain metastases (BMs) from small cell lung cancer (SCLC) a homogenous sample, and to identify the metastatic risk levels in brain regions.

Methods: T1-enhanced magnetic resonance imaging (MRI) from SCLC patients were retrospectively reviewed from three medical institutions in China. All images were registered to the standard brain template provided by the Montreal Neurological Institute (MNI) 152 database, followed by transformation of the location of all BMs to the space of standard brain. Read More

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Recording cortico-cortical evoked potentials of the human arcuate fasciculus under general anaesthesia.

Clin Neurophysiol 2021 May 1. Epub 2021 May 1.

Section of Neurosurgery, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address:

Objective: We examined the feasibility of using cortico-cortical evoked potentials (CCEPs) to monitor the major cortical white matter tract involved in language, the arcuate fasciculus (AF), during surgery under general anaesthesia.

Methods: We prospectively recruited nine patients undergoing surgery for lesions in the left peri-sylvian cortex, for whom awake surgery was not indicated. High angular resolution diffusion imaging (HARDI) tractography was used to localise frontal and temporal AF terminations, which guided intraoperative cortical strip placement. Read More

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Symptomatic eating epilepsy: two novel pediatric patients and review of literature.

Ital J Pediatr 2021 Jun 12;47(1):137. Epub 2021 Jun 12.

Pediatric Neurology and Muscular Disease Unit, IRCCS Istituto Giannina Gaslini", Genoa, Italy.

Eating epilepsy (EE) is a form of reflex epilepsy in which seizures are triggered by eating. It is a rare condition but a high prevalence has been reported in Sri Lanka. In EE, the ictal semiology includes focal seizures with or without secondary generalization or generalized seizures. Read More

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Clinical correlates of white matter lesions in Parkinson's disease using automated multi-modal segmentation measures.

J Neurol Sci 2021 Jun 1;427:117518. Epub 2021 Jun 1.

Singapore General Hospital, Singapore; Duke-NUS Medical School, Singapore. Electronic address:

Background: Age-related white matter lesions (WML) are common, impact neuronal connectivity, and affect motor function and cognition. In addition to pathological nigrostriatal losses, WML are also common co-morbidities in Parkinson's disease (PD) that affect postural stability and gait. Automated brain volume measures are increasingly incorporated into the clinical reporting workflow to facilitate precision in medicine. Read More

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The memory for words: Armand Trousseau on aphasia.

Richard Leblanc

J Hist Neurosci 2021 Jun 11:1-19. Epub 2021 Jun 11.

Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

Of all the nineteenth-century physicians whose names still resonate today, Armand Trousseau is perhaps the one most familiar, for his description of carpal spasm as a sign of hypocalcemia (Trousseau's sign) and his description of the hypercoagulable state associated with cancer (Trousseau's syndrome). In the last three years of his life, Trousseau turned his attention to aphasia, which he included in his 1864 and 1865 lectures given at Hôtel-Dieu Hospital in Paris and which he discussed in an address to the Imperial Academy of Medicine in 1865. Trousseau preceded Wernicke in describing aphasia as a symptom complex, in which he included Broca's aphemia, receptive aphasia, the inability to read with and without the inability to write (alexia with and without agraphia), the inability to name common objects (amnesic aphasia or anomia) and to recognize numbers (acalculia), and the inability to draw. Read More

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18F-THK5351 PET Can Identify Core Lesions in Different Amyotrophic Lateral Sclerosis Phenotypes.

Clin Nucl Med 2021 Jun 10. Epub 2021 Jun 10.

From the Department of Neurology, Tokyo Metropolitan Geriatric Hospital Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology Department of Diagnostic Radiology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.

Abstract: Two patients with different amyotrophic lateral sclerosis (ALS) phenotypes underwent 18F-THK5351 PET to visualize lesions undergoing astrogliosis by measuring monoamine oxidase B activity. Patient 1 was a 57-year-old man with flail leg syndrome. Elevated uptake was observed inside the motor cortex, corresponding to the leg area in a cortical homunculus. Read More

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Living with global amnesia: self-established compensation strategies of a patient with severe memory impairment - a narrative report.

Neurocase 2021 Jun 11:1-10. Epub 2021 Jun 11.

LMU Klinikum der Universität München, Neurologische Klinik und Poliklinik, Munich, Bayern, Germany.

We report the case of C.H., a 48-year-old patient with global amnesia caused by herpes simplex encephalitis at the age of 20 and subsequent extensive bilateral temporal lobe lesions. Read More

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Postoperatively determined high-risk histopathologic features in papillary thyroid carcinoma initially eligible for thyroid lobectomy: a game changer.

Endocrine 2021 Jun 10. Epub 2021 Jun 10.

Department of Surgical, Medical, Pathology, and Critical Care, The University of Pisa, Pisa, 56124, Italy.

Purpose: Recent clinical practice guidelines consider thyroid lobectomy a viable alternative for low-risk papillary thyroid carcinoma PTC measuring 1-4 cm in size. We aimed to assess the likelihood of finding postoperatively determined high-risk histopathologic features that would lead to the recommendation of completion thyroidectomy.

Methods: A retrospective review of patients who underwent total thyroidectomy for PTC measuring 1-4 cm in size between Jan 2012 and Jan 2018 was conducted. Read More

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Neuroimaging in pediatric temporal lobe epilepsy: Does neuroimaging accurately predict pathology and surgical outcome?

Epilepsy Res 2021 Jun 4;175:106680. Epub 2021 Jun 4.

Division of Pediatric Neurology, University of Alberta, Edmonton, Alberta, Canada; Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada.

Temporal lobe epilepsy (TLE) in children is considered different from that in adults. As such, characterizing the structural lesions present in pediatric patients with TLE and their association with long-term seizure control is important. Here, we aimed to assess the concordance between preoperative imaging and postoperative histopathological diagnoses and their associations with seizure outcomes in pediatric patients with TLE undergoing temporal lobe surgery. Read More

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Neural bases of color-specific semantic loss: Two cases of object-color knowledge impairment.

Cortex 2021 May 13;141:211-223. Epub 2021 May 13.

Department of Clinical Neuroscience, Yamagata University Graduate School of Medicine, Yamagata city, Yamagata, Japan; Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai city, Miyagi, Japan.

Human color processing includes perception, naming, and knowledge of colors. These facets are dissociable from each other and appear to have discrete neuronal bases. Here, we present two cases with loss of object color knowledge but spared color perception and knowledge of object other than color. Read More

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Durable Response to Immunotherapy With Antiangiogenic Drug in Large-Cell Lung Carcinoma With Multiple Fulminant Postoperative Metastases: A Case Report.

Front Oncol 2021 20;11:633446. Epub 2021 May 20.

Department of Thoracic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Immunotherapy alone or chemo-immunotherapy has recently been recommended for treating advanced lung carcinoma in patients without driver mutations. However, the efficacy of immunotherapy and molecular mechanism in large-cell lung cancer (LCLC) remains unclear. Here, we reported a rare case of multiple fulminant postoperative body and mouth metastases in LCLC treating with combination immunotherapy. Read More

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[A Case of Cerebral Tuberculoma].

No Shinkei Geka 2021 May;49(3):683-688

Department of Neurosurgery, Tokyo Medical and Dental University.

Cerebral tuberculoma is a rare and serious form of tuberculosis. Despite advancements in imaging and laboratory diagnostics, it is challenging to diagnose cerebral tuberculoma due to its insidious nature and nonspecific findings. A 56-year-old woman was referred to our hospital for headaches. Read More

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Wiad Lek 2021 ;74(5):1274-1276


Objective: The aim: To pay attention of clinicians to possible lesions of the central nervous system (encephalitis) in patients with COVID-19.

Patients And Methods: Case presentation: A 44-year-old woman was admitted to our clinic because of 2-month-history of mild fever, bilateral lower lobe pneumonia, respiratory failure, generalized weakness, and some neurologic symptoms. SARS-CoV-2 RNA was detected in nasopharyngeal swab. Read More

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Central Nervous System Involvement in Adult-Onset Hemophagocytic Lymphohistiocytosis.

Cureus 2021 May 1;13(5):e14792. Epub 2021 May 1.

Internal Medicine, Newark Beth Israel Medical Center, Newark, USA.

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease marked by high cytokine levels, uncontrolled lymphocyte, and macrophage proliferation. It is generally a systemic disorder with varying degrees of central nervous system (CNS) involvement, with the vast majority of cases affecting children. We report a case of CNS-HLH in a 51-year-old male who initially presented with fevers, night sweats, fatigue, bilateral arthralgia, and altered mental status. Read More

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Multiple nodular opacities only involving the right middle pulmonary lobe: Unusual manifestation of tuberculosis.

Clin Case Rep 2021 May 1;9(5):e04086. Epub 2021 Apr 1.

Department of Respiratory Medicine Koseiren Takaoka Hospital Takaoka Japan.

Bronchoscopy should be actively performed to differentiate pulmonary tuberculosis in patients with lesions in the middle lobe, which are unaccompanied by bronchiectasis or present without obvious lesions in other lobes. Read More

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Pediatric fibrolamellar hepatocellular carcinoma: case report and review of the literature.

Acta Chir Belg 2021 Jun 5;121(3):204-210. Epub 2019 Sep 5.

Department of Hepatobiliairy Surgery, Antwerp University Hospital, Antwerp, Belgium.

Background: A 13-year-old boy presented with acute abdominal pain in the right upper quadrant without previous trauma. Abdominal ultrasound (US) revealed a mass in the right liver lobe with free intraperitoneal fluid, suggestive for hemoperitoneum. Magnetic resonance imaging confirmed a subcapsular lesion (5. Read More

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A unique case of progressive hemifacial microsomia or Parry-Romberg syndrome associated with limb and brain anomalies with normal neurological findings: A review of the literature.

Eur J Med Genet 2021 May 31:104234. Epub 2021 May 31.

Division of Genetics and Metabolism, Department of Pediatrics, University of California, Irvine School of Medicine, Orange, CA. Electronic address:

In this report, we describe an unusual case of progressive hemifacial atrophy or Parry-Romberg syndrome in a 10-year-old girl with progressive hemifacial microsomia and limb anomalies who had brain magnetic resonance imaging (MRI) findings of white matter hyper-intensities. Patients typically present with neurological manifestations such as epilepsy, facial pain, and migraines and ophthalmological symptoms in conjunction with white matter lesions. The patient demonstrated normal cognition and psychomotor development despite the presence of white matter lesions in her frontal lobe that is commonly associated with neurological symptoms. Read More

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Magnetic resonance imaging-guided microwave ablation for lung tumor: a case report.

Quant Imaging Med Surg 2021 Jun;11(6):2780-2784

Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, China.

Thoracoscopic surgery is considered to be the best treatment option for pulmonary lesions. However, for patients with clinical stage IIIA, surgery is not always feasible, due to a lack of sufficient lung function. Microwave ablation (MWA) is an appropriate, minimally invasive treatment option for these patients. Read More

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Structural brain assessment of temporal lobe epilepsy based on voxel-based and surface-based morphological features.

Neurol Neurochir Pol 2021 Jun 2. Epub 2021 Jun 2.

Department of Neurosurgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Aim Of The Study: This study aimed to assess the cerebral voxel-based and surface-based morphological abnormalities of patients with temporal lobe epilepsy (TLE).

Materials And Methods: A total of 100 healthy adults and 73 patients with TLE were enrolled in this study, and their 3D T1-weighted MRI data were collected. Voxel-based morphology (VBM) and surface-based morphology (SBM) tools were used to compare the morphological differences between healthy adults and patients with TLE. Read More

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Forced Gazing: A Stimulus-bound Behavior.

Cogn Behav Neurol 2021 Jun 2;34(2):140-149. Epub 2021 Jun 2.

Department of Neuropsychiatry, Ashikaga Red Cross Hospital, Tochigi, Japan.

We studied four patients with acquired brain injury who were compelled to gaze at a moving object or the face of an individual who came into their sight, especially the person's eyes. The patients continued to gaze at the object or person until it disappeared from their sight. This behavior, referred to as forced gazing, is related to visual groping (part of the instinctive grasp reaction), and, together with a similar sign of visual grasping, constitutes a spectrum of visual stimulus-bound behaviors. Read More

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fMRI Retinotopic Mapping in Patients with Brain Tumors and Space-Occupying Brain Lesions in the Area of the Occipital Lobe.

Cancers (Basel) 2021 May 18;13(10). Epub 2021 May 18.

Department of Neurosurgery, University Hospital Regensburg, 93053 Regensburg, Germany.

Functional magnetic resonance imaging (fMRI) is a valuable tool in the clinical routine of neurosurgery when planning surgical interventions and assessing the risk of postoperative functional deficits. Here, we examined how the presence of a brain tumor or lesion in the area of the occipital lobe affects the results of fMRI retinotopic mapping. fMRI data were evaluated on a retrospectively selected sample of 12 patients with occipital brain tumors, 7 patients with brain lesions and 19 control subjects. Read More

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Lesion-Function Analysis from Multimodal Imaging and Normative Brain Atlases for Prediction of Cognitive Deficits in Glioma Patients.

Cancers (Basel) 2021 May 14;13(10). Epub 2021 May 14.

Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, 52428 Juelich, Germany.

Cognitive deficits are common in glioma patients following multimodality therapy, but the relative impact of different types and locations of treatment-related brain damage and recurrent tumors on cognition is not well understood. In 121 WHO Grade III/IV glioma patients, structural MRI, -(2-[18F]fluoroethyl)-L-tyrosine FET-PET, and neuropsychological testing were performed at a median interval of 14 months (range, 1-214 months) after therapy initiation. Resection cavities, T1-enhancing lesions, T2/FLAIR hyperintensities, and FET-PET positive tumor sites were semi-automatically segmented and elastically registered to a normative, resting state (RS) fMRI-based functional cortical network atlas and to the JHU atlas of white matter (WM) tracts, and their influence on cognitive test scores relative to a cohort of matched healthy subjects was assessed. Read More

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Hemostatic and Tissue Regeneration Performance of Novel Electrospun Chitosan-Based Materials.

Biomedicines 2021 May 21;9(6). Epub 2021 May 21.

Medical Institute, Sumy State University, 40007 Sumy, Ukraine.

The application of chitosan (Ch) as a promising biopolymer with hemostatic properties and high biocompatibility is limited due to its prolonged degradation time, which, in turn, slows the repair process. In the present research, we aimed to develop new technologies to reduce the biodegradation time of Ch-based materials for hemostatic application. This study was undertaken to assess the biocompatibility and hemostatic and tissue-regeneration performance of Ch-PEO-copolymer prepared by electrospinning technique. Read More

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CT Findings of Pulmonary Metastases from Primary Cardiac Angiosarcoma.

Curr Med Imaging 2021 May 21. Epub 2021 May 21.

Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Background: Primary cardiac angiosarcoma is a rare malignancy with high predilection to involve surrounding structures such as pulmonary metastases. We analysed the chest computed tomography (CT) imaging features of patients diagnosed with primary cardiac angiosarcoma with pulmonary metastases in this study.

Methods: This study retrospectively reviewed 12 patients with confirmed primary cardiac angiosarcoma, out of which eight (all men) with pulmonary metastasis were included in the analysis. Read More

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[Sleeve Lobectomy for Right Middle Lobe and S6 Segment Lung Cancer:Report of a Case].

Kyobu Geka 2021 Jun;74(6):469-471

Department of Thoracic Surgery, Osaka City University, Osaka, Japan.

A 76-year-old man showed an abnormal chest shadow at the follow-up of treated gastric cancer. Chest computed tomography revealed mass lesions in the right middle and left upper lobes, and bronchoscopy revealed a nodular lesion at the entrance of the right B6. The right middle lobe and B6 lesions were diagnosed as lung cancer, and sleeve resection for the right middle lobe and S6 segment was performed. Read More

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Virtual bronchoscopic navigation non-virtual bronchoscopic navigation assisted bronchoscopy for the diagnosis of peripheral pulmonary lesions: a systematic review and meta-analysis.

Ther Adv Respir Dis 2021 Jan-Dec;15:17534666211017048

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, No 1 Youyi Road, Yuzhong, Chongqing 400016, China.

Background: Image-guided bronchoscopy techniques such as virtual bronchoscopic navigation (VBN) has emerged as a means of assisting in the biopsy of peripheral pulmonary lesions. However, the role of VBN-assisted (VBNA) bronchoscopy in the diagnosing of peripheral pulmonary lesions (PPLs) has not been well established. This meta-analysis investigated the diagnostic yield of VBN-assisted non-VBN-assisted (NVBNA) bronchoscopy for PPLs. Read More

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Metastatic neuroendocrine tumor with metastases to the right liver in a patient with absent left portal vein.

J Surg Case Rep 2021 May 27;2021(5):rjab207. Epub 2021 May 27.

Department of Surgery, University of Hawai'i John A. Burns School of Medicine, Honolulu, HI, USA.

The patient is a 50-year-old female that underwent routine screening colonoscopy during which she was found to have a neuroendocrine tumor in the right colon. The patient underwent computed tomography and magnetic resonance imaging scans that demonstrated metastatic disease in segments 5 and 7 of the liver. Notably, the patient was found to have an absent left portal vein. Read More

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Isolated bladder metastasis from lung adenocarcinoma: a case report.

J Surg Case Rep 2021 May 27;2021(5):rjab195. Epub 2021 May 27.

Department of Urology, Charles Nicolle Hospital, Tunis, Tunisia.

Cancers of extra bladder origin represent between 2 and 12% of bladder neoplasms and are most often secondary to contiguous bladder invasion. Metastasis from distant organs is exceptional, especially from pulmonary adenocarcinoma with <10 cases identified over the last 20 years. We report here a new case of a 55-year-old patient with a recently diagnosed pulmonary adenocarcinoma referred to the urology department for macroscopic hematuria. Read More

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