7 results match your criteria loaa

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The alien octocoral is a biogenic substrate multiplier in artificial Brazilian shipwrecks.

Aquat Ecol 2021 Oct 8:1-18. Epub 2021 Oct 8.

Programa de Pós-Graduação em Biodiversidade-PPGBio, Universidade Federal Rural de Pernambuco, Recife, Pernambuco Brazil.

Despite the obvious negative effects caused by invasive species, some recent studies have shown that the impacts at local scale are diverse and not necessarily negative. Arborescent benthic organisms such as octocorals form three-dimensional structures capable of increasing the amount of substrate available and providing shelter for epibiont species. We investigated the role of the alien octocoral on the diversity of benthic communities in three shipwrecks on the north-eastern coast of Brazil. Read More

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October 2021

High-accuracy quantitative principle of a new compact digital PCR equipment: Lab On An Array.

Genomics Inform 2021 Sep 30;19(3):e34. Epub 2021 Sep 30.

Department of Bioconvergence Engineering, Dankook University, Yongin 16890, Korea.

Digital PCR (dPCR) is the third-generation PCR that enables real-time absolute quantification without reference materials. Recently, global diagnosis companies have developed new dPCR equipment. In line with the development, the Lab On An Array (LOAA) dPCR analyzer (Optolane) was launched last year. Read More

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September 2021

Diagnostic evaluation of qRT-PCR-based kit and dPCR-based kit for COVID-19.

Genes Genomics 2021 11 15;43(11):1277-1288. Epub 2021 Sep 15.

Department of Bio-Convergence Engineering, Dankook University, Jukjeon, 16890, Republic of Korea.

Background: Coronavirus disease of 2019 (COVID-19) is well known as a fatal disease, first discovered at Wuhan in China, ranging from mild to death, such as shortness of breath and fever. Early diagnosis of COVID-19 is a crucial point in preventing global prevalence.

Objective: We aimed to evaluate the diagnostic competency and efficiency with the Allplex™ 2019-nCoV Assay kit and the Dr. Read More

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November 2021

Comparative Analysis for Genetic Characterization in Korean Native Jeju Horse.

Animals (Basel) 2021 Jun 28;11(7). Epub 2021 Jun 28.

Center for Bio-Medical Engineering Core Facility, Dankook University, Cheonan 31116, Korea.

The Jeju horse is a native Korean species that has been breeding on Jeju Island since the 13th century. Their shape has a distinct appearance from the representative species, Thoroughbred. Here, we performed a comparison of the Jeju horse and Thoroughbred horse for the identification of genome-wide structure variation by using the next-generation sequencing (NGS) technique. Read More

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Comparison of two digital PCR methods for EGFR DNA and SARS-CoV-2 RNA quantification.

Clin Chim Acta 2021 Oct 16;521:9-18. Epub 2021 Jun 16.

Biomolecular Measurement Team, Korea Research Institute of Standards and Science, Daejeon, Republic of Korea. Electronic address:

Background: The COVID-19 pandemic caused by the severe acute SARS-CoV-2 virus has undeniably highlighted the importance of reliable nucleic acid quantification. Digital PCR (dPCR) is capable of the absolute quantification of nucleic acids.

Method: By using the droplet dPCR (QX200) and the digital real-time PCR (LOAA), the copy numbers were compared via multiple assays for three distinct targerts; EGFR DNA, SARS-CoV-2 and HIV-1 RNA. Read More

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October 2021

Lead optimization attrition analysis (LOAA): a novel and general methodology for medicinal chemistry.

Drug Discov Today 2015 Aug 24;20(8):978-87. Epub 2015 Mar 24.

Lead Generation Candidate Realization, Sanofi, 94400 Vitry sur Seine, France.

Herein, we report a novel and general method, lead optimization attrition analysis (LOAA), to benchmark two distinct small-molecule lead series using a relatively unbiased, simple technique and commercially available software. We illustrate this approach with data collected during lead optimization of two independent oncology programs as a case study. Easily generated graphics and attrition curves enabled us to calibrate progress and support go/no go decisions on each program. Read More

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Effect of dietary arachidonic acid on metabolism of deuterated linoleic acid by adult male subjects.

Lipids 1998 May;33(5):471-80

USDA, ARS, NCAUR, Food Quality and Safety Research, Peoria, Illinois 61604, USA.

The influence of dietary supplementation with 20:4n-6 on uptake and turnover of deuterium-labeled linoleic acid (18:2n-6[d2]) in human plasma lipids and the synthesis of desaturated and elongated n-6 fatty acids from 18:2n-6[d21 were investigated in six adult male subjects. The subjects were fed either a high-arachidonic acid (HIAA) diet containing 1.7 g/d or a low-AA (LOAA) diet containing 0. Read More

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