Neuroimage 2021 Sep 10;244:118566. Epub 2021 Sep 10.
Translational Neurocircuitry Group, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931, Cologne, Germany; Cluster of Excellence in Cellular Stress Responses in Aging Associated Diseases (CECAD), University of Cologne, 50931, Cologne, Germany.
Our increasing knowledge about gut-brain interaction is revolutionising the understanding of the links between digestion, mood, health, and even decision making in our everyday lives. In support of this interaction, the vagus nerve is a crucial pathway transmitting diverse gut-derived signals to the brain to monitor of metabolic status, digestive processes, or immune control to adapt behavioural and autonomic responses. Hence, neuromodulation methods targeting the vagus nerve are currently explored as a treatment option in a number of clinical disorders, including diabetes, chronic pain, and depression. Read More