Viruses 2021 04 20;13(4). Epub 2021 Apr 20.
Department of Microbiology and Immunology, Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, Future University in Egypt, Cairo 11835, Egypt.
Complications of hepatitis C virus (HCV) chronic infection cause ~400,000 deaths worldwide annually. One complication, liver fibrosis, is influenced by host genetic factors. Genes influencing fibrosis include immune, metabolic, oxidative stress, and viral entry genes, such as interleukin 10 (), microsomal triglyceride-transfer protein (), superoxide dismutase-2 (), and apolipoprotein E ()-encoding genes, respectively. Read More