798,163 results match your criteria life support


Assessment of Central Sensitization in Breast Cancer Survivors: Convergent Validity and Use of the Central Sensitization Inventory (CSI) and Its Short-Form as a Clustering Tool.

Clin Pract 2021 Sep 7;11(3):607-618. Epub 2021 Sep 7.

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy, Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, 1050 Brussel, Belgium.

The Central Sensitization Inventory (CSI) measurement properties in patients having nonspecific, noncancer pain are well-established. However, studies examining the reliability and validity of either the CSI or the Central Sensitization Inventory short-form version (CSI-9) in breast cancer survivors (BCS) are scarce. The purpose was to evaluate convergent validity and internal consistency of the CSI and CSI-9. Read More

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September 2021

Arteriovenous Fistula Flow Dysfunction Surveillance: Early Detection Using Pulse Radar Sensor and Machine Learning Classification.

Biosensors (Basel) 2021 Aug 26;11(9). Epub 2021 Aug 26.

Department of Medical Imaging and Radiological Science, I-Shou University, Kaohsiung City 82445, Taiwan.

Vascular Access (VA) is often referred to as the "Achilles heel" for a Hemodialysis (HD)-dependent patient. Both the patent and sufficient VA provide adequacy for performing dialysis and reducing dialysis-related complications, while on the contrary, insufficient VA is the main reason for recurrent hospitalizations, high morbidity, and high mortality in HD patients. A non-invasive Vascular Wall Motion (VWM) monitoring system, made up of a pulse radar sensor and Support Vector Machine (SVM) classification algorithm, has been developed to detect access flow dysfunction in Arteriovenous Fistula (AVF). Read More

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Mediterranean diet and cognitive function: From methodology to mechanisms of action.

Free Radic Biol Med 2021 Sep 22. Epub 2021 Sep 22.

Charles Perkins Center, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, NSW, Australia; Department of Clinical and Experimental Sciences, Brescia University School of Medicine, Brescia, Italy.

The traditional Mediterranean diet (MedDiet), rich in minimally processed plant foods and fish, has been widely recognized to be one of the healthiest diets. Data from multiple randomized clinical trials have demonstrated its powerful effect against oxidative stress, inflammation and the development and progression of cardiovascular disease, type 2 diabetes, and other metabolic conditions that play a crucial role in the pathogenesis of neurodegenerative diseases. The protecting effects of the MedDiet against cognitive decline have been investigated in several observational and experimental studies. Read More

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September 2021

Vicariance and Dispersal Events Inferred from Mitochondrial Genomes and Nuclear Genes (18S, 28S) Shaped Global Cryptocercus Distributions.

Mol Phylogenet Evol 2021 Sep 22:107318. Epub 2021 Sep 22.

College of Plant Protection, Southwest University, Beibei, Chongqing 400716, P. R. China. Electronic address:

Cryptocercus Scudder, a genus of wingless, subsocial cockroaches, has low vagility but exhibits a disjunct distribution in eastern and western North America, and in China, South Korea and the Russian Far East. This distribution provides an ideal model for testing hypotheses of vicariance through plate tectonics or other natural barriers versus transoceanic dispersal or across other natural barriers. We sequenced 45 Cryptocercus mitochondrial genomes to resolve phylogenetic relationships among members of the genus worldwide. Read More

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September 2021

Bridge to Sapien: Mechanical Circulatory Support as a Bridge to Transcatheter Mitral Intervention.

Ann Thorac Surg 2021 Sep 22. Epub 2021 Sep 22.

Division of Cardiothoracic Surgery, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY.

Veno-arterial membrane oxygenation (VA-ECMO) can be used as a rescue therapy for patients in refractory cardiogenic shock. While there is experience as a bridge-to-transplant and bridge-to-ventricular assist device in the heart failure population, there are not reports of its use as a bridge to definitive valvular intervention. Here we present a case of VA-ECMO as a bridge to transcatheter mitral valve-in-valve (TMVIV) with a Sapien aortic prosthesis (Edwards Life Sciences, Irvine, CA). Read More

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September 2021

The arbitrium system controls prophage induction.

Curr Biol 2021 Sep 22. Epub 2021 Sep 22.

Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow G12 8TA, UK; MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London SW7 2AZ, UK. Electronic address:

Some Bacillus-infecting bacteriophages use a peptide-based communication system, termed arbitrium, to coordinate the lysis-lysogeny decision. In this system, the phage produces AimP peptide during the lytic cycle. Once internalized by the host cell, AimP binds to the transcription factor AimR, reducing aimX expression and promoting lysogeny. Read More

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September 2021

Functional Social Support and Perceived Stress of Nurses Working in Secular and Religious Hospitals.

J Natl Black Nurses Assoc 2021 Sep;32(1):35-40

Tree of Life Sowright Enterprise, LLC, P.O. BOX 2283, Apopka, FL 32704

Nurses experience high levels of stress. In this study, functional social support and perceived stress of nurses working in secular and religious hospitals were examined. The social support model, the job demands-resources theory, and the transactional model of stress guided this study. Read More

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September 2021

Covid-19, Pregnancy, and Vaccinations.

J Natl Black Nurses Assoc 2021 Sep;32(1):1-9

Florida International University, Miami, FL.

Pregnancy in the presence of COVID-19 increases the risk for illness severity. Data suggest that pregnant women with COVID-19 are more likely to be hospitalized, to be admitted to the intensive care unit, and to require life support. Vaccination is currently considered the most effective preventive intervention against COVID-19 in the United States. Read More

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September 2021

Xerostomia: an immunotherapy-related adverse effect in cancer patients.

Support Care Cancer 2021 Sep 25. Epub 2021 Sep 25.

University of Washington Medicine/Seattle Cancer Care Alliance, Seattle, WA, USA.

Purpose: Xerostomia is an underrecognized adverse effect of immunotherapy (IO) that can significantly impact patients' quality of life by leading to poor nutritional status, dental caries, and oral candidiasis. The purpose of this case series was to describe the onset, severity, clinical course, and management of IO-induced xerostomia.

Methods: This was a retrospective case series conducted at an outpatient cancer center. Read More

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September 2021

A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy.

Support Care Cancer 2021 Sep 25. Epub 2021 Sep 25.

Division of Hematology-Oncology, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, 5150 Center Ave, Suite 564, Pittsburgh, PA, 15232, USA.

Purpose: Central venous catheters (CVCs) are widely used in acute myeloid leukemia (AML) patients. Complications associated with CVCs are frequently encountered and contribute to morbidity and mortality. Prospective studies investigating and comparing complications of different types of CVCs in AML patients and their effects on the quality of life are limited. Read More

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September 2021

Social context factors and refugee children's emotional health.

Soc Psychiatry Psychiatr Epidemiol 2021 Sep 25. Epub 2021 Sep 25.

Human Early Learning Partnership, School of Population and Public Health, University of British Columbia, Vancouver, Canada.

Background: Refugee children face numerous challenges associated with pre-migration trauma and post-migration adaptation. Much research pertaining to refugee children's well-being focuses on psychiatric symptoms. Relatively few studies have examined how social context factors-such as perceptions of peer belonging, and support from adults at home and at school-contribute to the emotional health of refugee children. Read More

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September 2021

Long-term diet quality and its change in relation to late-life subjective cognitive decline.

Am J Clin Nutr 2021 Sep 25. Epub 2021 Sep 25.

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Background: Evidence regarding the role of diet quality, especially its change, in subjective cognitive decline (SCD) is scarce.

Objectives: To examine associations of long-term diet qualities, including Alternate Mediterranean Diet (AMED), Dietary Approaches to Stop Hypertension (DASH), and Alternate Healthy Eating Index 2010 (AHEI-2010) with SCD in the Nurses' Health Study.

Methods: We followed 49,493 female registered nurses averaged 48 years from 1984 to 2014. Read More

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September 2021

Comparison of 12 and 24-hours shift impacts on ICU nursing care, efficiency, safety, and work-life quality.

Int Nurs Rev 2021 Sep 25. Epub 2021 Sep 25.

Visiting Professor, Editor in Chief, International Nursing Review, Faculty of Nursing Chiang Mai, Chiang Mai University, Bangkok, Thailand.

Background: Nursing care quality is a central concern of health policy, and nurses' shift schedules affect the quality of care and their work-life status internationally. A lack of reliable information on the differences between 24- and 12-h shifts on care quality, nursing care quality, patient safety, and adverse and missed events warranted investigation in Cambodia.

Aim: We aimed to examine the impacts of 12-h shifts compared with 24-h shifts. Read More

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September 2021

Incidence and disability-adjusted life years of maternal disorders at the global, regional, and national levels from 2007 to 2017: A systematic analysis for the Global Burden of Disease Study 2017.

Int J Gynaecol Obstet 2021 Sep 24. Epub 2021 Sep 24.

School of Medicine, Ningbo University, Ningbo, Zhejiang, China.

Objective: To report the global burden of maternal disorders and their main subcategories in 195 countries and territories between 2007 and 2017.

Methods: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 estimated maternal disease burden at global, regional, and country levels. Maternal disorders were disaggregated into 10 categories, and estimated incidence and disability-adjusted life years (DALYs) of maternal disorders were reported separately. Read More

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September 2021

Effectiveness of mobile health-based self-management interventions in breast cancer patients: a meta-analysis.

Support Care Cancer 2021 Sep 24. Epub 2021 Sep 24.

School of Nursing, Sun Yat-Sen University, No.74 Zhong Shan Second Road, Guangzhou, 510078, China.

Purpose: To determine the effectiveness of mobile health-based self-management interventions on medical/behavioral, role, and emotional management in breast cancer patients.

Methods: The Embase, MEDLINE, SINOMED, the Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), WanFang, and Weipu (VIP) databases were extensively searched from inception to November 30, 2020, to identify eligible clinical trials. Outcomes included medical/behavioral management (self-management behavior, functional exercise compliance, self-efficacy, complications, and symptoms), role management (role functioning), and emotional management (anxiety and depression), social support, and health-related quality of life. Read More

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September 2021

Effects of β-glucan, probiotics, and synbiotics on obesity-associated colitis and hepatic manifestations in C57BL/6J mice.

Eur J Nutr 2021 Sep 24. Epub 2021 Sep 24.

Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju, 63241, Republic of Korea.

Purpose: Probiotics and prebiotics are commonly used to improve the gut microbiota. Since prebiotics can support the growth of probiotics, co-administration of these is called synbiotics. It has been demonstrated that obesity-induced gut dysbiosis can worsen inflammatory bowel disease symptoms. Read More

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September 2021

A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.

Cell Res 2021 Sep 24. Epub 2021 Sep 24.

State Key Laboratory of Membrane Biology, Beijing, China.

Under stress, the endomembrane system undergoes reorganization to support autophagosome biogenesis, which is a central step in autophagy. How the endomembrane system remodels has been poorly understood. Here we identify a new type of membrane contact formed between the ER-Golgi intermediate compartment (ERGIC) and the ER-exit site (ERES) in the ER-Golgi system, which is essential for promoting autophagosome biogenesis induced by different stress stimuli. Read More

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September 2021

Nuclear preservation in the cartilage of the Jehol dinosaur Caudipteryx.

Commun Biol 2021 Sep 24;4(1):1125. Epub 2021 Sep 24.

Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, 142 Xizhimenwai dajie, Beijing, 100044, China.

Previous findings on dinosaur cartilage material from the Late Cretaceous of Montana suggested that cartilage is a vertebrate tissue with unique characteristics that favor nuclear preservation. Here, we analyze additional dinosaur cartilage in Caudipteryx (STM4-3) from the Early Cretaceous Jehol biota of Northeast China. The cartilage fragment is highly diagenetically altered when observed in ground-sections but shows exquisite preservation after demineralization. Read More

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September 2021

Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells.

Sci Rep 2021 Sep 24;11(1):19051. Epub 2021 Sep 24.

Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.

Head and neck cancer (HNC) has frequently an aggressive course for the development of resistance to standard chemotherapy. Thus, the use of innovative therapeutic drugs is being assessed. Bortezomib is a proteasome inhibitor with anticancer effects. Read More

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September 2021

Metaplastic reinforcement of long-term potentiation in hippocampal area CA2 by cholinergic receptor activation.

J Neurosci 2021 Sep 24. Epub 2021 Sep 24.

Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117 597

Hippocampal CA2, an inconspicuously positioned area between the well-studied CA1 and CA3 subfields, has captured research interest in recent years due to its role in social memory formation. However, the role of cholinergic inputs to the CA2 area for the regulation of synaptic plasticity remains to be fully understood. We show that cholinergic receptor activation with the non-selective cholinergic agonist, carbachol (CCh), triggers a protein synthesis-dependent and NMDAR-independent long-term synaptic depression (CCh-LTD) at entorhinal cortical (EC)-CA2 and Schaffer collateral (SC)-CA2 synapses in the hippocampus of adult male Wistar rats. Read More

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September 2021

Barriers and facilitators of type 1 diabetes self-care in adolescents and young adults.

J Pediatr Nurs 2021 Sep 21. Epub 2021 Sep 21.

Department of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, Monza, Italy. Electronic address:

Purpose: This study explores the disease experience of adolescents and young adults with T1DM focusing on the barriers and facilitators that characterise their disease self-care. Self-care requires complex decision making and cooperation between patients, their families, the healthcare team, and the social support system. Personal and social factors affect self-care, and specific challenges impact adolescents and young adults, putting them at a higher risk of poor glycaemic control and more severe complications. Read More

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September 2021

Cellulose nanofibril/carbon nanotube composite foam-stabilized paraffin phase change material for thermal energy storage and conversion.

Carbohydr Polym 2021 Dec 20;273:118585. Epub 2021 Aug 20.

Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea; Laboratory of Natural Materials Technology, Åbo Akademi University, Turku 20500, Finland. Electronic address:

The leakage and low thermal conductivity of paraffin phase change material (PCM) must be addressed to achieve a more efficient energy storage process. In this study, cellulose nanofibril (CNF) foams were prepared as the porous support of paraffin to prevent its leakage, and multiwalled carbon nanotubes (CNTs) were incorporated in the foams to improve heat transfer performance. Treatment of CNF with methyltrimethoxysilane improved compatibility between the foams and paraffin. Read More

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December 2021

Associations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer's disease plasma biomarkers: a 7T MRI study.

Alzheimers Res Ther 2021 Sep 24;13(1):159. Epub 2021 Sep 24.

Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Alzheimer Centre Limburg, Maastricht University, UNS40 box 34, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.

Background: The brainstem locus coeruleus (LC) constitutes the intersection of the initial pathophysiological processes of Alzheimer's disease (AD) and sleep-wake dysregulation in the preclinical stages of the disease. However, the interplay between in vivo assessment of LC degeneration and AD-related sleep alterations remains unknown. Here, we sought to investigate whether MRI-assessed LC structural integrity relates to subjective sleep-wake measures in the context of AD plasma biomarkers, in cognitively unimpaired older individuals. Read More

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September 2021

Society, family, and individual characteristics as double-edged swords in the social reintegration of Iranian female survivors from unintentional severe burns: a qualitative study of enablers and barriers.

BMC Womens Health 2021 Sep 24;21(1):339. Epub 2021 Sep 24.

Patient Safety Research Centre, Urmia University of Medical Sciences, Urmia, Iran.

Background: Reintegrating to society is a significant challenge during burn survivors' rehabilitation.

Aim: This study aims to describe what Iranian female survivors from unintentional severe burns experience as enablers and barriers of social reintegration (SR).

Methods: Fourteen adult female burn survivors whose burns were unintentional participated in this qualitative study. Read More

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September 2021

Genome-wide analysis of HSP70 gene superfamily in Pyropia yezoensis (Bangiales, Rhodophyta): identification, characterization and expression profiles in response to dehydration stress.

BMC Plant Biol 2021 Sep 24;21(1):435. Epub 2021 Sep 24.

Key Laboratory of Utilization and Conservation of Tropical Marine Bioresource (Hainan Tropical Ocean University), Ministry of Education, Sanya, 572022, China.

Background: Heat shock proteins (HSPs) perform a fundamental role in protecting plants against abiotic stresses. Individual family members have been analyzed in previous studies, but there has not yet been a comprehensive analysis of the HSP70 gene family in Pyropia yezoensis.

Results: We investigated 15 putative HSP70 genes in Py. Read More

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September 2021

miR-24 and its target gene Prdx6 regulate viability and senescence of myogenic progenitors during aging.

Aging Cell 2021 Sep 24:e13475. Epub 2021 Sep 24.

Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.

Satellite cell-dependent skeletal muscle regeneration declines during aging. Disruptions within the satellite cells and their niche, together with alterations in the myofibrillar environment, contribute to age-related dysfunction and defective muscle regeneration. In this study, we demonstrated an age-related decline in satellite cell viability and myogenic potential and an increase in ROS and cellular senescence. Read More

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September 2021

Reduced-dose intravenous thrombolysis for acute intermediate high-risk pulmonary embolism: Rationale and design of the PEITHO-3 trial.

Thromb Haemost 2021 Sep 24. Epub 2021 Sep 24.

Hopital Europeen Georges Pompidou, Paris, France.

Intermediate high-risk pulmonary embolism (PE) is characterised by right ventricular (RV) dysfunction and elevated circulating cardiac troponin levels despite apparent haemodynamic stability at presentation. In these patients, full-dose systemic thrombolysis reduced the risk of haemodynamic decompensation or death but increased the risk of life-threatening bleeding. Reduced-dose thrombolysis may be capable of improving safety while maintaining reperfusion efficacy. Read More

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September 2021

Factors associated with Work-Life Balance and Productivity before and during Work from Home.

J Occup Environ Med 2021 Sep 23. Epub 2021 Sep 23.

Technology Transfer and Business Development Office, University of the Philippines Manila (Tejero), College of Nursing, University of the Philippines Manila (Tejero), Industrial and Systems Engineering, Gokongwei College of Engineering, De La Salle University, Manila, Philippines (Seva), Department of Environmental and Occupational Health, College of Public Health, University of the Philippines Manila (Fadrilan-Camacho).

Objectives: Considering the prevailing work from home (WFH) arrangement globally due to COVID-19, this paper aims to compare job-related and psychosocial factors before and during WFH setup; and to determine the relationship of these factors to work-life balance (WLB) and productivity.

Methods: A total 503 employees from 46 institutions answered the online questionnaire, 318 of whom met the inclusion criteria. Paired t-test and structural equation modeling (SEM) with multi-group analysis were used for the statistical analyses. Read More

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September 2021

Is Foot Drop an Underreported Sequela of Extracorporeal Membrane Oxygenation?

ASAIO J 2021 Sep 20. Epub 2021 Sep 20.

From the Center for Advanced Heart Failure, Memorial Hermann Hospital-Texas Medical Center, Houston, Texas Department of Advanced Cardiopulmonary Therapies and Transplantation, University of Texas Health Science Center at Houston, Houston, Texas Rehabilitation Services, Memorial Hermann Hospital-Texas Medical Center, Houston, Texas.

Foot drop in the absence of limb ischemia is a chronic complication in peripheral venoarterial extracorporeal membrane oxygenation (V-A ECMO) survivors; however, there is little published regarding the incidence and functional outcomes of this condition. Common peroneal nerve is the most common cause of foot drop, a condition that leads to significant debility and requires extensive physical therapy and rehabilitation, thereby affecting the patient's quality of life. We completed a retrospective review of 153 patients who received femoral cannulation for V-A ECMO support for greater than 1 hour. Read More

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September 2021

Factors Correlated With Fear of Cancer Recurrence in Cancer Survivors: A Meta-analysis.

Cancer Nurs 2021 Sep 23. Epub 2021 Sep 23.

Author Affiliations: School of Nursing, China Medical University (Drs Zhang and Li); School of Nursing, Liaoning University of Traditional Chinese Medicine (Dr Sun); and Department of Gynecology, Cancer Hospital of China Medical University (Dr Qin), Shenyang; School of Nursing, Norman Bethune Health Science Center of Jilin University (Ms Liu), Changchun; and Department of Neurosurgery, The First Hospital of China Medical University Shenyang (Dr Jiang).

Background: Fear of cancer recurrence (FCR) is one of the most common and aversive psychological phenomena among cancer survivors. Understanding the independent and potentially modifiable risk factors that contribute toward FCR seen in cancer survivors would inform future interventional trials aimed at reducing this risk.

Objective: The aim of this study was to provide an evidence synthesis of factors correlated with FCR to inform the development of preventive interventions. Read More

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September 2021