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Cervical lymph node tuberculosis and TNF, IL8, IL10, IL12B and IFNG polymorphisms.

New Microbiol 2021 Jan 14;44(1):24-32. Epub 2021 Jan 14.

Departamento de Biología Molecular e Histocompatibilidad, Hospital General "Dr. Manuel Gea González", Calzada de Tlalpan 4800, Col. Sección XVI, CP 14080, Ciudad de México, México.

Cervical lymph node tuberculosis (LNTB) is the most common manifestation of extrapulmonary tuberculosis, resulting from the interaction of environmental and genetic factors. The immune response against TB is regulated by several cytokines, which have single nucleotide polymorphisms (SNPs), leading to different levels of expression. The aim of this study was to evaluate the association of LNTB with the TNF, IL8, IL10, IL12B and IFNG gene polymorphisms in Mexican patients. Read More

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January 2021
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