Mol Nutr Food Res 2021 Jun 15:e2100417. Epub 2021 Jun 15.
Y. Yuan, X. Chen, Y. Sun, Y. Fan, L. Zheng, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Scope: DNA methylation contributes to obesity, but the role of the DNA demethylase ten-eleven translocation protein 1 (Tet1) in obesity remains unclear. Vitamin C is a cofactor for the Tet family of proteins, but whether vitamin C can be used to treat obesity via Tet1 awaits clarification.
Methods And Results: Tet1 and Tet1 mice were fed a high fat diet (HFD). Read More