97,442 results match your criteria level knowledge

Refeeding syndrome occurs among older adults regardless of refeeding rates: A systematic review.

Nutr Res 2021 May 21;91:1-12. Epub 2021 May 21.

Department of Nursing and Health Promotion, Faculty of Health Sciences, Oslo Metropolitan University, Oslo 0130, Norway; Regional Advisory Unit for Palliative Care, Department of Oncology, Oslo University Hospital, Oslo 0424, Norway. Electronic address:

Refeeding syndrome is a life-threatening clinical disorder that can occur when treating malnutrition. The aim was to examine the current knowledge of refeeding syndrome in patients ≥ 65 + years with special focus on the incidence of hypophosphatemia (HP) in relation to refeeding rate (kcal/kg/day), number of days until the lowest level of phosphate occurs (day of nadir), refeeding rates and adverse events, and death. Specifically, we hypothesized that higher energy provision would cause a higher incidence of HP. Read More

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Healthcare professional's choice for surgical management of stress urinary incontinence in a U.K. tertiary hospital.

Eur J Obstet Gynecol Reprod Biol 2021 May 24;263:7-14. Epub 2021 May 24.

Department of Urogynaecology, King's College Hospital, London, UK.

Objective: In July 2018, NHS England, introduced a pause on vaginal mesh, including the mid-urethral sling (MUS) for treatment of stress urinary incontinence (SUI). NICE guidelines recommend MUS as one of the surgical options for SUI. The aim of our study was to investigate healthcare professionals choices for surgical treatment of SUI, if conservative measures failed. Read More

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Attitudes, beliefs and behaviors of religiosity, spirituality, and cultural competence in the medical profession: A cross-sectional survey study.

PLoS One 2021 15;16(6):e0252750. Epub 2021 Jun 15.

University of South Carolina School of Medicine Greenville, Greenville, South Carolina, United States of America.

Introduction: Religion and spirituality play important roles in the lives of many, including healthcare providers and their patients. The purpose of this study was to examine the relationships between religion, spirituality, and cultural competence of healthcare providers.

Methods: Physicians, residents, and medical students were recruited through social platforms to complete an electronically delivered survey, gathering data regarding demographics, cultural competency, religiosity, and spirituality. Read More

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Design of a Littrow-type diode laser with independent control of cavity length and grating rotation.

Opt Lett 2021 Jun;46(12):2840-2843

We present a novel, to the best of our knowledge, extended-cavity diode laser based on a modified Littrow configuration. The coarse wavelength adjustment via the rotation of a diffraction grating is decoupled from the fine tuning of the external cavity modes by positioning a piezo transducer behind the diode laser, making the laser robust against misalignment and hysteresis even with long external cavities. Two laser prototypes with external cavities of different lengths were tested with a 780 nm laser diode, and locked to an atomic reference. Read More

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Elke Bräuer-Krisch: Dedication, creativity and generosity: May 17, 1961- September 10, 2018.

Jean A Laissue

Int J Radiat Biol 2021 Jun 15:1-24. Epub 2021 Jun 15.

Institute of Pathology, University of Bern, Switzerland.

Purpose: This extraordinary woman worked her professional way from a radiation protection engineer to become the successful principal investigator of a prestigious international European project for a new radiation therapy (ERC Synergy grant, HORIZON 2020). The evaluation of the submitted proposal was very positive. The panel proposed that it be funded. Read More

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Involvement of Jordanian Head Nurses' in Health Policy Development: A Cross-Sectional Study.

Policy Polit Nurs Pract 2021 Aug;22(3):230-238

Community and Mental Health Nursing Department, Jordan University of Science and Technology, Irbid, Jordan.

Background: Despite the importance of involving nurses in health policy, nurse's involvement faces many challenges. Literature showed that there is a low level of nurses' and nurse leaders' involvement in health policy development.

Aim: The aims of this study were to examine (a) the level of Jordanian head nurses' involvement in health policy development and their perceived benefits and barriers; (b) the relationships between level of knowledge, competence, and interest in health policy and the level of involvement in health policy development; and (c) the relationship between the level of self-efficacy (efficacy expectation and outcome expectation) and the level of involvement in health policy development. Read More

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Satisfaction and stress levels of dentistry students relating to distance education.

Dent Med Probl 2021 Jun 15. Epub 2021 Jun 15.

Department of Pediatric Dentistry, Faculty of Dentistry, Nuh Naci Yazgan University, Kayseri, Turkey.

Background: It is not known whether the coronavirus disease 2019 (COVID-19) pandemic has affected dentistry education.

Objectives: This study aimed to determine the satisfaction and stress levels of dentistry students in Turkey regarding distance education during the COVID-19 pandemic, and to evaluate their opinions on this matter.

Material And Methods: This cross-sectional research study was conducted from October to November 2020 with the use of a web-based questionnaire consisting of 3 sections. Read More

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The converging path of protein SUMOylation in phytohormone signalling: highlights and new frontiers.

Plant Cell Rep 2021 Jun 15. Epub 2021 Jun 15.

National Agri-Food Biotechnology Institute (NABI), Sector-81 (Knowledge City), S.A.S. Nagar, Mohali, Punjab, 140306, India.

Key Message: The intersection of phytohormone signalling pathways with SUMOylation, a key post-translational modification, offers an additional layer of control to the phytohormone signalling for sophisticated regulation of plant development. Plants live in a constantly changing environment that are often challenging for the growth and development of plants. Phytohormones play a critical role in modulating molecular-level changes for enabling plants to resist climatic aberrations. Read More

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What Is the Risk of Intraoperative Cerebral Oxygen Desaturation in Patients Undergoing Shoulder Surgery in the Beach Chair Position?

Clin Orthop Relat Res 2021 06 15. Epub 2021 Jun 15.

Department of Anesthesiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Previous studies have shown that intraoperative cerebral desaturation in patients undergoing shoulder surgery in the beach chair position varies widely, from 0% to 80%. To our knowledge, the risk of intraoperative cerebral desaturation is not known after all identified intraoperative modifiable physiologic parameters that influence cerebral blood flow have been controlled for.

Questions/purposes: (1) What is the risk of intraoperative cerebral desaturation during shoulder surgery with the patient in the beach chair position when patients received combined general anesthesia and an interscalene block, and what other factors associated with intraoperative cerebral desaturation can be identified? (2) Is intraoperative cerebral desaturation associated with 24-hour cognitive decline? (3) What factors are associated with intraoperative hypotension?

Methods: Between April and December 2020, 51 patients underwent elective shoulder surgery in the beach chair position at one center. Read More

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A comparative study of the efficiency and safety of chemotherapy as a therapeutic method for recurrent or resistant gestational trophoblastic neoplasia: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2021 Jun;100(24):e26263

Department of Obstetrics and Gynecology, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.

Background: Gestational trophoblastic neoplasia (GTN) is an infrequent spectrum of placental malignant cases. Generally, single-agent or multiple-agent chemotherapy is used to treat the condition. The condition has a significant impact on women in the childbearing age, which makes post-chemo fertility and obstetrical results a significant contemplation. Read More

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Constructing High-Fidelity Phenotype Knowledge Graphs for Infectious Diseases With a Fine-Grained Semantic Information Model: Development and Usability Study.

J Med Internet Res 2021 Jun 15;23(6):e26892. Epub 2021 Jun 15.

Suzhou Institute of Systems Medicine, Suzhou, China.

Background: Phenotypes characterize the clinical manifestations of diseases and provide important information for diagnosis. Therefore, the construction of phenotype knowledge graphs for diseases is valuable to the development of artificial intelligence in medicine. However, phenotype knowledge graphs in current knowledge bases such as WikiData and DBpedia are coarse-grained knowledge graphs because they only consider the core concepts of phenotypes while neglecting the details (attributes) associated with these phenotypes. Read More

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Adherence to and patient's knowledge of self-management of subcutaneous biologic therapy in chronic inflammatory rheumatic diseases: results of a multicentre cross-sectional study.

Clin Exp Rheumatol 2021 May 28. Epub 2021 May 28.

Department of Rheumatology - Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, and INSERM (UMR1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France.

Objectives: Non-adherence to biologic therapy is an issue in chronic inflammatory rheumatic diseases (CIRDs) and might be related to poor patient knowledge of the risk of these therapies. Our aim here was to evaluate the level of patient adherence to and knowledge of self-care safety skills for biologic therapy.

Methods: This was a multicentre, cross-sectional study in which out-patients visited an office- or hospital-based rheumatologist. Read More

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Assessment of the Awareness Level of Radiation Protection Among Radiographers Working in the Medical Imaging Wards of the Hospitals in Zanjan, Iran.

Radiat Prot Dosimetry 2021 Jun 15. Epub 2021 Jun 15.

Department of Radiology Technology, School of Paramedical Sciences, Zanjan University of Medical Sciences, Zanjan, Iran.

X-ray usage in medical diagnosis could have hurtful effects for both patient and medical imaging wards' personnel as a result of failure to follow radiation protection (RP) principles (shielding, distance and time) by radiographers. This cross-sectional descriptive-analytical study was carried out by valid and reliable online questionnaire, which was completed by 103 radiographers. Data were analyzed by using descriptive statistics (mean, standard deviation and frequency) and analytical statistics (Pearson's correlation coefficient test, Student's independent t-test and analysis of variance test) in the Statistical Package for Social Sciences version 20 (sig: P < 0. Read More

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Impact of the model of long-term follow-up care on adherence to guideline-recommended surveillance among survivors of adolescent and young adult cancers.

Cancer Med 2021 Jun 15. Epub 2021 Jun 15.

University of Toronto, Institute of Medical Science, Toronto, Canada.

Purpose: Adolescent and young adult cancer survivors require lifelong healthcare to address the late effects of therapy. We examined the impact of different provider models of long-term follow-up (LTFU) care on adherence to recommended surveillance.

Methods: We conducted a retrospective cohort study using administrative health databases in Ontario, Canada. Read More

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Resting Heart Rate Mediates the Relationship between Parenting Style and Callous-Unemotional Traits in Chinese Children.

Res Child Adolesc Psychopathol 2021 Jun 14. Epub 2021 Jun 14.

Department of Psychology, Guangzhou University, Guangzhou, P. R. China.

Despite increasing knowledge of social and biological risk factors for callous-unemotional (CU) traits, relatively less is known about how these two sets of risk factors combine to affect these traits. The current longitudinal study investigated pathways from parenting style to CU traits via resting heart rate in a three-year project. Parents of 382 children completed the Parenting Styles and Dimensions Questionnaire at Time 1 (children Mean age = 9. Read More

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Neocortical circuits in pain and pain relief.

Nat Rev Neurosci 2021 Jun 14. Epub 2021 Jun 14.

Institute of Pharmacology, Heidelberg University, Heidelberg, Germany.

The sensory, associative and limbic neocortical structures play a critical role in shaping incoming noxious inputs to generate variable pain perceptions. Technological advances in tracing circuitry and interrogation of pathways and complex behaviours are now yielding critical knowledge of neocortical circuits, cellular contributions and causal relationships between pain perception and its abnormalities in chronic pain. Emerging insights into neocortical pain processing suggest the existence of neocortical causality and specificity for pain at the level of subdomains, circuits and cellular entities and the activity patterns they encode. Read More

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Integrating spatial analysis and questionnaire survey to better understand human-onager conflict in Southern Iran.

Sci Rep 2021 Jun 14;11(1):12423. Epub 2021 Jun 14.

USDA Forest Service Rocky Mountain Research Station, 2500 S. Pine Knoll, Flagstaff, AZ, USA.

Southern Iran is a conservation priority area for the endangered Persian onager (Equus hemionus onager), which is threatened by habitat fragmentation and conflict with local communities. To better understand factors that influence onager conservation, we administered a questionnaire in local communities to survey their ecological knowledge, personal experience related to onager, and attitudes toward traditional solutions for reducing crop damage by onager. In addition, we used resistant kernel and factorial least-cost path analyses to identify core areas and corridors for onager movement, and spatial randomization of vehicle collisions and crossing locations to test the predictive ability of resistant kernel and factorial least-cost path predictions of movement. Read More

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Effects of pill splitting training on drug physiochemical properties, compliance, and clinical outcomes in the elderly population: a randomised trial.

Hong Kong Med J 2021 Jun 11. Epub 2021 Jun 11.

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong.

Introduction: This study aimed to provide information about the clinical and physiochemical effects of pill splitting training in elderly cardiac patients in Hong Kong.

Methods: A parallel study design was adopted. Patients taking lisinopril, amlodipine, simvastatin, metformin, or perindopril who needed to split pills were recruited from the Prince of Wales Hospital. Read More

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Effectiveness of a Blended-Learning Intervention in Teachers' Vocal Health.

J Voice 2021 Jun 11. Epub 2021 Jun 11.

Federal University of Paraíba (UFPB), Department of Speech Therapy, João Pessoa (PB), Brazil. Electronic address:

Objective: To verify the effectiveness of a blended-learning voice assistance program for elementary school teachers.

Study Design: Nonrandomized and comparative interventional clinical trial.

Methods: A total of 59 teachers participated; 33 of the 59 teachers participated in face-to-face learning (control group-CG), and 26 of the 59 teachers participated in blended learning (experimental group-EG). Read More

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Incidence of metastasis to level V lymph nodes in clinically positive necks among Sri Lankan patients with oral squamous cell carcinoma.

Br J Oral Maxillofac Surg 2020 Sep 28. Epub 2020 Sep 28.

National Dental Hospital Colombo, Sri Lanka. Electronic address:

Oral squamous cell carcinoma (OSCC) remains the most common cancer among males in Sri Lanka. Metastasis to neck is a crucial prognostic factor. A modified radical/radical neck dissection including levels I -V, was performed in patients with OSCC who had a clinically positive neck (cN+). Read More

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September 2020

Deep ensemble multitask classification of emergency medical call incidents combining multimodal data improves emergency medical dispatch.

Artif Intell Med 2021 Jul 13;117:102088. Epub 2021 May 13.

Biomedical Data Science Laboratory (BDSLab), Instituto de Aplicaciones de las Tecnologías de la Información y de las Comunicaciones Avanzadas (ITACA), Universitat Politècnica de València (UPV), Camino de Vera s/n, 46022 Valencia, Spain.

The objective of this work was to develop a predictive model to aid non-clinical dispatchers to classify emergency medical call incidents by their life-threatening level (yes/no), admissible response delay (undelayable, minutes, hours, days) and emergency system jurisdiction (emergency system/primary care) in real time. We used a total of 1 244 624 independent incidents from the Valencian emergency medical dispatch service in Spain, compiled in retrospective from 2009 to 2012, including clinical features, demographics, circumstantial factors and free text dispatcher observations. Based on them, we designed and developed DeepEMC, a deep ensemble multitask model integrating four subnetworks: three specialized to context, clinical and text data, respectively, and another to ensemble the former. Read More

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Interpreting deep learning models for epileptic seizure detection on EEG signals.

Artif Intell Med 2021 Jul 1;117:102084. Epub 2021 May 1.

Embedded Systems Laboratory (ESL), EPFL, Lausanne, Switzerland.

While Deep Learning (DL) is often considered the state-of-the art for Artificial Intel-ligence-based medical decision support, it remains sparsely implemented in clinical practice and poorly trusted by clinicians due to insufficient interpretability of neural network models. We have approached this issue in the context of online detection of epileptic seizures by developing a DL model from EEG signals, and associating certain properties of the model behavior with the expert medical knowledge. This has conditioned the preparation of the input signals, the network architecture, and the post-processing of the output in line with the domain knowledge. Read More

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Public support for healthy supermarket initiatives focused on product placement: a multi-country cross-sectional analysis of the 2018 International Food Policy Study.

Int J Behav Nutr Phys Act 2021 Jun 14;18(1):78. Epub 2021 Jun 14.

Global Obesity Centre (GLOBE), Institute for Health Transformation, Deakin University, 221 Burwood Highway, Burwood VIC, Geelong, 3125, Australia.

Background: Food retail environments have an influential role in shaping purchasing behavior and could contribute to improving dietary patterns at a population level. However, little is known about the level of public support for different types of initiatives to encourage healthy food choices in supermarkets, and whether this varies across countries or context. The current study aimed to explore the level of support for three potential supermarket initiatives focused on product placement across five countries, and factors that may influence this support. Read More

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Which factors contribute to sexual well-being? A comparative study among 17 to 20 year old boys and girls in Belgium and Ecuador.

Cult Health Sex 2021 Jun 14:1-17. Epub 2021 Jun 14.

Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.

Despite recognition that sexual well-being is an important part of adolescent sexual and reproductive health, a clear description of adolescent sexual well-being does not yet exist. Through six in-depth interviews and four focus group discussions with 56 young people in two distinct contexts (Belgium and Ecuador), we used the social-ecological framework to identify factors influencing adolescent sexual well-being. According to respondents, the main factors that influence adolescent sexual well-being are not only situated at the individual (having knowledge and skills and being physically, sexually and mental mature and healthy) and interpersonal levels (positive attraction towards others and communication about sexuality), but at a broader societal level, including social acceptance of sex, gender and sexual diversity and its (legal) translation into comprehensive sexuality education and the ready availability of contraceptives. Read More

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Socioeconomic Status and Rurality Among Patients With Head and Neck Cancer.

Otolaryngol Head Neck Surg 2021 Jun 15:1945998211019278. Epub 2021 Jun 15.

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Southern Illinois University, Springfield, Illinois, USA.

Objective: Describe the relationship among rurality, socioeconomic status (SES), and patient/tumor characteristics in patients presenting with head and neck cancer.

Study Design: Retrospective single-institution study.

Setting: Academic tertiary-level medical center. Read More

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A complete picture of protein unfolding and refolding in surfactants.

Chem Sci 2019 Nov 22;11(3):699-712. Epub 2019 Nov 22.

Interdisciplinary Nanoscience Center (iNANO), Department of Chemistry, Aarhus University Gustav Wieds Vej 14 DK - 8000 Aarhus C Denmark

Interactions between proteins and surfactants are of relevance in many applications including food, washing powder formulations, and drug formulation. The anionic surfactant sodium dodecyl sulfate (SDS) is known to unfold globular proteins, while the non-ionic surfactant octaethyleneglycol monododecyl ether (CE) can be used to refold proteins from their SDS-denatured state. While unfolding have been studied in detail at the protein level, a complete picture of the interplay between protein and surfactant in these processes is lacking. Read More

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November 2019

Factors influencing nursing students' intention to accept COVID-19 vaccination: A pooled analysis of seven European countries.

Nurse Educ Today 2021 Jun 10;104:105010. Epub 2021 Jun 10.

Department of Nursing, School of Health Sciences, Hellenic Mediterranean University, Crete, Greece. Electronic address:

Background: Experiencing the third wave of COVID-19 pandemic, high vaccination coverage by a safe and effective vaccine globally would be a great achievement. Acceptance of vaccination by nursing students is an important issue as they play a decisive role as future professionals in educating patients, counselling, and guiding them to the right clinical decision.

Objectives: To explore the intention of nursing students to get vaccinated for SARS-CoV-2 infection and the factors acting either as motivators or as barriers towards vaccination. Read More

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Substitutes mimic the exposure behaviour of REACH regulated phthalates - A review of the German HBM system on the example of plasticizers.

Int J Hyg Environ Health 2021 Jun 11;236:113780. Epub 2021 Jun 11.

German Environment Agency (UBA), Berlin, Germany.

The population is constantly exposed to potentially harmful substances present in the environment, including inter alia food and drinking water, consumer products, and indoor air. Human biomonitoring (HBM) is a valuable tool to determine the integral, internal exposure of the general population, including vulnerable subgroups, to provide the basis for risk assessment and policy advice. The German HBM system comprises of five pillars: (1) the development of suitable analytical methods for new substances of concern, (2) cross-sectional population-representative German Environmental Surveys (GerES), (3) time trend analyses using archived samples from the Environmental Specimen Bank (ESB), (4) the derivation of health-based guidance values as a risk assessment tool, and (5) transfer of data into the European cooperation network HBM4EU. Read More

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Evaluation of knowledge, attitudes and practices of health services vocational schools' students with regard to COVID-19.

Gac Med Mex 2021 ;157(1):70-75

Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.

Introduction: The most critical intervention to control SARS-CoV-2 infection requires appropriate knowledge and attitude towards the virus.

Objective: To determine the level of knowledge, attitudes and practices of students of a health services' vocational school with regard to COVID-19.

Methods: Cross-sectional study carried out between May and June 2020 in a university of the Turkish region. Read More

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January 2021

General practitioners' knowledge about pregnancy complications associated with long-term cardiovascular risk.

Gac Med Mex 2021 ;157(1):47-51

Division of Endocrinology, Diabetes and Hypertension, Brigham & Women's Hospital, Harvard Medical School, Boston, United States.

Introduction: Cardiovascular disease (CVD) is the leading cause of mortality in women; preeclampsia (PE) and gestational diabetes mellitus (GDM) are associated with an increased risk of CVD.

Objective: To evaluate general practitioners (GP) knowledge about complicated pregnancies and their association with CVD.

Methods: An anonymous case-based electronic questionnaire designed to assess the level of understanding on the influence of a history of pregnancy complications on long-term cardiovascular risk and general knowledge about CVD risk was sent to GPs. Read More

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January 2021