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Regression of taxane-related cystoid macular edema after topical dorzolamide treatment: two case reports.

J Med Case Rep 2021 Jul 21;15(1):355. Epub 2021 Jul 21.

Department of Ophthalmology, Asahikawa Medical University, 2-1-1-1 Midorigaoka Higashi, Asahikawa, Hokkaido, Japan.

Background: Cystoid macular edema is a rare, vision-threatening side effect of the taxane family of anticancer agents. There is no established treatment or standard treatment protocol for taxane-related cystoid macular edema. Here, we report two cases of taxane-related cystoid macular edema that were treated with topical dorzolamide. Read More

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Orbital nodular fasciitis in the pediatric population: a case report and review of the literature.

Orbit 2021 Jul 20:1-6. Epub 2021 Jul 20.

Department of Ophthalmology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

A 10-month-old female presented with a rapidly growing, painless mass in the right upper eyelid. Due to suspected malignancy, she underwent an urgent biopsy. Histopathological and immunohistochemical analyses revealed nodular fasciitis. Read More

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Metachronous common iliac lymph node metastasis after rectosigmoid colon cancer resection: A case report.

Int J Surg Case Rep 2021 Jul 15;85:106203. Epub 2021 Jul 15.

Department of Surgery, Division of Gastroenterological, General and Transplant Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan. Electronic address:

Introduction And Importance: Metastases to common iliac lymph nodes from cancer of the rectosigmoid are extremely rare. We report a patient with a right common iliac lymph node metastasis after rectosigmoid cancer resection.

Case Presentation: The patient is a 57-year-old woman diagnosed with rectosigmoid cancer (Stage IIIc) who underwent laparoscopic resection followed by 8 courses of adjuvant chemotherapy with capecitabine. Read More

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External Validation of the IOTA Classification in Women with Ovarian Masses Suspected to Be Endometrioma.

J Clin Med 2021 Jul 1;10(13). Epub 2021 Jul 1.

Endometriosis Center of Excellence, Department of Obstetrics and Gynecology, Sheba Medical Center, Ramat-Gan 5262000, Israel.

The study aimed to perform external validation of the International Ovarian Tumor Analysis (IOTA) classification of adnexal masses as benign or malignant in women with suspected endometrioma. A retrospective study including women referred to an endometriosis tertiary referral center for dedicated transvaginal ultrasound (TVUS). Adnexal masses were evaluated using the IOTA classification simple descriptors, simple rules and expert opinion. Read More

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Multimodal approach in the pre-surgical evaluation of focal epilepsy surgery candidates: how far are we from a non-invasive ESI-based "sourcectomy"?

Epileptic Disord 2021 Jul 16. Epub 2021 Jul 16.

Unit of Child Neuropsychiatry, Department of Medical and Surgical Neuroscience and Rehabilitation, IRCCS Istituto Giannina Gaslini, Genoa, Italy, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.

The management of drug-resistant patients with focal epilepsy is often challenging. Surgery is recognised as a useful and effective treatment option. The identification of the epileptogenic zone relies on the integration of clinical, neurophysiological, and neuroimaging findings. Read More

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F-fluorodeoxyglucose positron emission tomography-based prediction for splenectomy in patients with suspected splenic lymphoma.

Ann Transl Med 2021 Jun;9(12):1009

Department of Hematology, Huadong Hospital, Fudan University, Shanghai, China.

Background: Diagnostic splenectomy is often performed on patients with suspected splenic lymphoma. However, unnecessary splenectomy entails more harm than benefit for patients. Therefore, a preliminary screening method for patients with suspected splenic lymphoma that has high sensitivity and specificity is urgently needed. Read More

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Lung Biopsy in Coronavirus-19 Pneumonia: A Case Report and Review of Literature.

J Coll Physicians Surg Pak 2021 07;31(7):117-119

Department of Hepatobiliary Surgery, Shifa International Hospital, Islamabad, Pakistan.

Pneumonia is one of the major manifestations of infection by the novel coronavirus (COVID-19) virus. CT scans are used as first line investigation in suspected cases. Biopsies are almost never done. Read More

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Evaluation of Laryngeal Vascular Changes with Image1 S Enhancement System In Reference To The European Laryngological Society Guideline.

Clin Otolaryngol 2021 Jul 16. Epub 2021 Jul 16.

Department of Otorhinolaryngology, Head and Neck Surgery, Ankara University School of Medicine, Ankara, Turkey.

Objectives: To assess the feasibility of using Image1 S™ endoscopic enhancement system for discrimination of the vascular patterns in laryngeal lesions.

Design: Forty patients presenting with benign, dysplastic and malignant laryngeal lesions were examined with Image1 S system. The vascular patterns were classified by a group of authors according to the European Laryngological Society (ELS) guideline, as perpendicular or longitudinal, in all lesions. Read More

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Adopting MR-guided stereotactic laser ablations for epileptic lesions: initial clinical experience and lessons learned.

Acta Neurochir (Wien) 2021 Jul 16. Epub 2021 Jul 16.

Functional Neurosurgery Unit, Department of Neurosurgery, Tel-Aviv Medical Center, Tel-Aviv, Israel.

Objective: MR-guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique for ablating brain lesions under real-time MRI feedback and control of the ablation process. The Medtronic Visualase system was recently approved for use in Europe and Israel. We report our initial technical experience using the system in the first 16 cases in which the system was used to ablate focal epileptogenic lesions. Read More

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Mixed Pial-Dural Arteriovenous Malformation in the Anterior Cranial Fossa Mimicking Dural Arteriovenous Fistula.

Asian J Neurosurg 2021 Apr-Jun;16(2):418-422. Epub 2021 May 28.

Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Mixed pial-dural arteriovenous malformation (MpdAVM) and dural arteriovenous fistula (dAVF) are rare entities in the anterior cranial fossa (ACF). As dural-pial vascular anastomosis can exist near the cribriform plate, MpdAVM with a small nidus, which cannot be apparently identified, can be logically indistinguishable from dAVF in ACF. A 71-year-old man was referred for evaluation of possible intracranial vascular malformation. Read More

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Traumatic Osteonecrosis of the Distal Ulna.

J Hand Surg Am 2021 Jul 12. Epub 2021 Jul 12.

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA.

A 46-year-old male was referred to our clinic for persistent ulnar-sided wrist pain 9 weeks after sustaining a traumatic injury while playing volleyball. The patient unsuccessfully underwent nonoperative management for a suspected injury to the triangular fibrocartilage complex. After magnetic resonance imaging revealed a lesion of the distal ulna, he was treated with diagnostic wrist arthroscopy and Bowers hemiresection. Read More

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When hiccups mean something more than just a nuisance: A rare presentation of pyogenic liver abscess.

JGH Open 2021 Jul 22;5(7):837-838. Epub 2021 Jun 22.

Department of Gastroenterology and Hepatology Medical College of Georgia at Augusta University Augusta Georgia USA.

Pyogenic liver abscess (PLA) is an uncommon yet potentially fatal disease. The disease most commonly arises from biliary infection but may also result from hematogenous seeding and portal spread secondary to bowel contamination, direct seeding, or penetrating trauma. The diagnosis is suspected when there is a hepatic lesion on imaging. Read More

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Traumatic Pseudoaneurysm Arising From Proximal Facial Artery: A Case Report and Literature Review.

Ear Nose Throat J 2021 Jul 14:1455613211033110. Epub 2021 Jul 14.

Department of Otorhinolaryngology, Habib Bourguiba Hospital, Sfax, Tunisia.

Pseudoaneurysms of facial artery usually arise from the distal part of the vessel. Only 4 cases were described in the literature involving the proximal part of facial artery. We present a case of a traumatic pseudoaneurysm involving the proximal part of facial artery. Read More

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Suture granuloma mimicking local recurrence of colon cancer after open right hemicolectomy: a case report.

Surg Case Rep 2021 Jul 14;7(1):164. Epub 2021 Jul 14.

Division of Colorectal Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.

Background: Foreign body granuloma is a rare surgery-related complication that can masquerade as cancer recurrence during postoperative surveillance. It may therefore deceive clinicians and lead to unnecessary interventions. The case presented herein demonstrates how a foreign body granuloma can be misleading in preoperative radiological studies and why this condition should not be ignored in differential diagnoses during surveillance of patients with previous history of abdominal surgery of any kind. Read More

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Arthroscopic Management of Giant Cell Tumor of the Calcaneus.

Foot Ankle Spec 2021 Jul 14:19386400211029120. Epub 2021 Jul 14.

Department of Orthopaedic and Traumatology, Sanglah Hospital; Faculty of Medicine, University of Udayana, Bali, Indonesia.

Giant cell tumor of the calcaneal bone is a very rare entity and generally seen in the 30 to 40 years age group. We report a case of a 17-year-old male with giant cell tumor of the calcaneus, presented with left heel pain without another obvious physical abnormality. Radiographs showed a lobulated, well-defined, lytic lesion of the calcaneus with narrow transitional zone without periosteal reaction, no extraosseal spread, and no lung metastases. Read More

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Juxtaglomerular cell tumor diagnosed preoperatively by renal tumor biopsy.

IJU Case Rep 2021 Jul 7;4(4):207-209. Epub 2021 Apr 7.

Department of Urology Kyoto Prefectural University of Medicine Kyoto-City Kyoto Japan.

Introduction: Diagnosis of small renal tumor from imaging analysis is limited. We report a case of juxtaglomerular cell tumor diagnosed preoperatively by renal tumor biopsy.

Case Presentation: A 17-year-old male was urgently hospitalized for acute-onset congestive heart failure. Read More

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FractalCovNet architecture for COVID-19 Chest X-ray image Classification and CT-scan image Segmentation.

Biocybern Biomed Eng 2021 Jul-Sep;41(3):1025-1038. Epub 2021 Jul 8.

Department of Information Technology, Rajalakshmi Engineering College, Chennai, India.

Precise and fast diagnosis of COVID-19 cases play a vital role in early stage of medical treatment and prevention. Automatic detection of COVID-19 cases using the chest X-ray images and chest CT-scan images will be helpful to reduce the impact of this pandemic on the human society. We have developed a novel FractalCovNet architecture using Fractal blocks and U-Net for segmentation of chest CT-scan images to localize the lesion region. Read More

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Severe Chemosis: Initial Misdiagnosis of an Emergent Complication of Acute Rhinosinusitis.

J Emerg Med 2021 Jul 10. Epub 2021 Jul 10.

Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Korea.

Background: Orbital findings such as cellulitis, ophthalmoplegia, and proptosis are possible complications of sinusitis. Acute sinusitis can also cause a conjunctival cyst-like lesion induced by severe chemosis; however, it is an uncommon complication.

Case Report: We report the case of a 53-year-old man who presented to our facility's emergency department. Read More

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[Plasm trimethylamine-N-oxide level and association with lesion severity in coronary heart disease patients with type 2 diabetes mellitus].

Zhonghua Xin Xue Guan Bing Za Zhi 2021 Jul 24;49(7):680-686. Epub 2021 Jul 24.

Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.

To investigate the association between trimethylamine-N-oxide (TMAO) and the degree of coronary atherosclerosis in coronary heart diseases (CHD) patients with type 2 diabetes mellitus. Consecutive patients, who underwent coronary angiography due to suspected CHD in Beijing Hospital from November 2016 to January 2018, were screened in this cross-sectional study. According to blood glucose level, previous medical history and coronary angiography results, they were divided into CHD without type2 diabetes mellitus(CHD-nDM) group and CHD with type2 diabetes mellitus(CHD-DM) group. Read More

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Optimizing diagnostic and staging pathways for suspected lung cancer: a decision analysis.

Chest 2021 Jul 10. Epub 2021 Jul 10.

Professor, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

Background: The optimal diagnostic and staging strategy for patients with suspected lung cancer is not known.

Research Question: What diagnostic and staging strategies are most cost-effective for lung cancer?

Study Design And Methods: A decision model was developed using a hypothetical patient with a high probability of lung cancer. Sixteen unique permutations of bronchoscopy with fluoroscopy, radial endobronchial ultrasound (rEBUS), electromagnetic navigation, convex EBUS (cEBUS) with or without rapid-onsite evaluation (ROSE), computed tomography guided biopsy (CTBx) and surgery were evaluated. Read More

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A Case of Spontaneous Regression and Recurrence of Primary Vitreoretinal Lymphoma.

Ocul Immunol Inflamm 2021 Jul 13:1-4. Epub 2021 Jul 13.

Department of Ophthalmology, Institute of Vision Research, Severance Eye Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

: To report a case of primary vitreoretinal lymphoma (PVRL) showing recurrence after spontaneous regression, diagnosed with the aid of next-generation sequencing (NGS).: Retrospective case report.: A 61-year-old immunocompetent Korean woman presented with subretinal lesions suspected of PVRL, which resolved spontaneously in 2 months. Read More

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[Pancreatic adenocarcinoma:a case containing a cyst enclosing a dilated tubular gland duct].

Nihon Shokakibyo Gakkai Zasshi 2021 ;118(7):679-685

Department of Gastroenterology, Shinshu University School of Medicine.

This case report describes a 73-year-old woman with pancreatic adenocarcinoma who had undergone a colectomy for colorectal cancer in 1995 and a right mastectomy and axillary dissection for breast cancer in 2013. In January 2019, a tumor, approximately 20mm in diameter, was detected in the pancreatic body. It contained a cyst noted to have delayed perfusion towards the center on abdominal computed tomography. Read More

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Successful surgical and medical treatment of a severe, acute epidural bleed in a young dog due to steroid responsive meningitis-arteritis.

Acta Vet Scand 2021 Jul 10;63(1):27. Epub 2021 Jul 10.

Small Animal Clinic-Neurosurgery, Neuroradiology and Clinical Neurology, Justus Liebig University-Giessen, Frankfurterstrasse 114, 35392, Giessen, Germany.

Background: Steroid responsive meningitis-arteritis (SRMA) is an immune-mediated disease of the leptomeninges and its associated blood vessels, typically responsive to corticosteroids. Clinically relevant haemorrhage is a rare finding in such patients and for this reason surgical decompression of the spinal cord is normally not considered. The diagnosis of SRMA is supported by serum C-reactive protein (CRP) increase, cerebrospinal fluid (CSF) examination, including cytology (polymorphonuclear pleocytosis in the acute form), nucleated cell-, red blood cell- and protein count, as well as by evaluating CSF and serum IgA concentrations. Read More

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Toward optical spectroscopy-guided lung biopsy: Demonstration of tissue-type classification.

J Biophotonics 2021 Jul 10:e202100132. Epub 2021 Jul 10.

Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.

The diagnostic yield of standard tissue-sampling modalities of suspected lung cancers, whether by bronchoscopy or interventional radiology, can be nonoptimal, varying with the size and location of lesions. What is needed is an insitu sensor, integrated in the biopsy tool, to objectively distinguish among tissue types in real time, not to replace biopsy with an optical diagnostic, but to verify that the sampling tool is properly located within the target lesion. We investigated the feasibility of elastic scattering spectroscopy (ESS), coupled with machine learning, to distinguish lung lesions from the various nearby tissue types, in a study with freshly-excised lung tissues from surgical resections. Read More

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Evaluation of Ultrafast Wave-Controlled Aliasing in Parallel Imaging 3D-FLAIR in the Visualization and Volumetric Estimation of Cerebral White Matter Lesions.

AJNR Am J Neuroradiol 2021 Jul 8. Epub 2021 Jul 8.

Department of (C.N., A.L.M.G.F., M.G.F.L., S.F.C., K.S., J.E.K., Q.T., Q.F, D.P., J.C., S.Y.H.), Massachusetts General Hospital, Boston, Massachusetts

Background And Purpose: Our aim was to evaluate an ultrafast 3D-FLAIR sequence using Wave-controlled aliasing in parallel imaging encoding (Wave-FLAIR) compared with standard 3D-FLAIR in the visualization and volumetric estimation of cerebral white matter lesions in a clinical setting.

Materials And Methods: Forty-two consecutive patients underwent 3T brain MR imaging, including standard 3D-FLAIR (acceleration factor = 2, scan time = 7 minutes 50 seconds) and resolution-matched ultrafast Wave-FLAIR sequences (acceleration factor = 6, scan time = 2 minutes 45 seconds for the 20-channel coil; acceleration factor = 9, scan time = 1 minute 50 seconds for the 32-channel coil) as part of clinical evaluation for demyelinating disease. Automated segmentation of cerebral white matter lesions was performed using the Lesion Segmentation Tool in SPM. Read More

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Isolated Musculocutaneous Nerve Injury in a Professional Baseball Player: A Case Report.

J Orthop Case Rep 2021 Mar;11(3):113-116

Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.

Introduction: Musculocutaneous nerve lesion in a throwing athlete is a rare condition. We report the case of a professional baseball pitcher with an isolated musculocutaneous nerve lesion that occurred during a pitching motion.

Case Presentation: The patient had radiating pain in the upper arm and weakness of elbow flexion. Read More

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Cerebral Venous Sinus Thrombosis Caused by Neuro-Behçet Disease Accidentally Detected by 68Ga-FAPI PET/CT.

Clin Nucl Med 2021 Jul 6. Epub 2021 Jul 6.

From the Department of Nuclear Medicine Fujian Provincial Key Laboratory of Precision Medicine for Cancer, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China.

Abstract: A 26-year-old man presented with recurrent oral ulcer, temporal headache, and blurred vision for 4 months. The giant cell arteritis was suspected, and 18F-FDG and 68Ga-FAPI PET/CT were done. There was no hypermetabolic lesion in 18F-FDG PET/CT. Read More

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Incidental diagnosis of nonfunctional bladder paraganglioma: a case report and literature review.

BMC Urol 2021 Jul 8;21(1):98. Epub 2021 Jul 8.

Department of Urology, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, China.

Background: Nonfunctional bladder paragangliomas is a rare urological disease. It may present clinical, radiology and pathological features similar to bladder cancer, Only scarce reports have been reported. Urologist must identify this generally benign neuroendocrine neoplasm to avoid misdiagnosis. Read More

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Correlation between FDG-PET uptake and survival in patients with primary brain tumors.

Am J Nucl Med Mol Imaging 2021 15;11(3):196-206. Epub 2021 Jun 15.

Center for Quantitative Cancer Imaging, Huntsman Cancer Institute, University of Utah Salt Lake, UT, USA.

This study evaluates F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) semi-quantitative analysis as biomarker of tumor aggressiveness and predictor of survival in patients with primary brain tumors. Semi-quantitative analyses (SUVmax, SUVmean) were derived from FDG PET images in 78 patients with suspected recurrence of primary brain tumors based on MRI. SUVmax and the ratio of lesion SUVmax to the SUVmean of contralateral white matter (SUVmax/WM) were measured. Read More

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Late presentation of extrauterine adenomyomas after laparoscopic morcellation at hysterectomy: a case report.

BMC Womens Health 2021 07 7;21(1):269. Epub 2021 Jul 7.

College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Healthcare City, Building 14, 505055, Dubai, United Arab Emirates.

Background: An adenomyoma is a well circumscribed form of adenomyosis and can be located within the myometrium, in the endometrium as a polyp, or extrauterine with the last being the rarest presentation amongst the three. With the ongoing advancement in gynecological surgery, the use of electromechanical morcellators have made the removal of large and dense specimens possible with minimally invasive techniques. However, it has also caused an increase in complications which were previously rare. Read More

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