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Trauma Case Rep 2021 Jun 11;33:100455. Epub 2021 Mar 11.

Orthopaedic and Trauma Unit, Hospital "Maggiore della Carità", Novara, Italy.

Bilateral posterior dislocation of the glenohumeral joint is an uncommon event, that can be missed at the initial presentation. We report the case of a 76-year old woman, who suffered a traumatic bilateral posterior dislocation, that was diagnosed three months later. She underwent surgical treatment on both shoulders in a single stage. Read More

J Neurol Sci 2021 Apr 3;425:117435. Epub 2021 Apr 3.

Department of Neurology, University of Florida College of Medicine, Gainesville, FL, USA. Electronic address:

Diffusion weighted imaging (DWI) is a widely used imaging technique to evaluate patients with stroke. It can detect brain ischemia within minutes of stroke onset. However, DWI has few potential pitfalls that should be recognized during interpretation. Read More

Cureus 2021 Mar 4;13(3):e13691. Epub 2021 Mar 4.

Division of Hematology/Oncology, University of California, Irvine School of Medicine, Irvine, USA.

Although non-small-cell lung cancer occasionally presents as cavitary lesions, it is rare for small-cell lung cancer (SCLC) to present or progress in such a manner. If a cavitary lesion is seen in the setting of small-cell lung carcinoma, infectious etiologies must be excluded first. We present the case of a 43-year-old man with refractory SCLC that progressed despite two lines of therapy, and who was ultimately found to have recurrent adenopathy and numerous widespread cavitary lung nodules. Read More

J Pak Med Assoc 2021 02;71(2(A)):553-555

Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

First described in 1934, eccrine spiradenoma (ES) is a rare, benign adnexal tumour arising from eccrine sweat glands. It commonly presents as a slow-growing nodule on the upper trunk, and head and neck region, mostly in the age bracket of 15-35 years, with no gender preference. While no established guidelines exist for optimal management of malignant ES, some therapies have been studied. Read More

J Urol 2021 Apr 5:101097JU0000000000001766. Epub 2021 Apr 5.

USC Institute of Urology and Catherine & Joseph Aresty, Department of Urology, Center for Image-Guided and Focal Therapy for Prostate Cancer, University of Southern California, Los Angeles, California.

Purpose: To evaluate the prostate cancer (PCa) and clinically significant PCa (CSPCa) detection on systematic (SB), target biopsy (TB) alone and combined SB and TB in men with Prostate Imaging Reporting and Data System (PIRADS)-5 lesion.

Material And Methods: From a prospectively maintained prostate biopsy (PBx) database, we identified consecutive patients with PIRADS 5 lesion on multiparametric magnetic resonance imaging (mpMRI). The patients underwent mpMRI followed by transrectal TB of PIRADS 5 lesion and 12-core SB. Read More

J Wrist Surg 2021 Apr 27;10(2):164-168. Epub 2020 Aug 27.

Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.

 Fracture-dislocations of all four ulnar (second to fifth) carpometacarpal (CMC) joints are rare hand injuries and frequently overlooked or missed. These injuries can be treated conservatively when closed reduction is successfully achieved, though they are sometimes irreducible and unstable.  We report the case of a 17-year-old boy involved in a vehicular accident. Read More

Rev Med Suisse 2021 Mar;17(732):630-634

Unité de dermatochirurgie, Service de dermatologie et vénéréologie, Département des spécialités de médecine, HUG, 1211 Genève 14.

Cutaneous tumours can be ill-delineated and subclinical tumour can be missed when using the usual methods of pathology processing because only less than 1 % of the margin is examined. Micrographic surgery was developed to allow for examination of 100 % of the margin. It reduces the recurrence rate and spares healthy tissue thus reducing lesion size and facilitating reconstruction. Read More

J Nucl Med 2021 Mar 31. Epub 2021 Mar 31.

Lund university and Skåne University Hospital, Lund, Sweden.

Prostate-specific membrane antigen (PSMA) radiopharmaceuticals used with positron emission tomography/computed tomography (PET-CT) are a promising tool for managing patients with prostate cancer. This study aimed to determine the accuracy of F-PSMA-1007 PET-CT for detecting tumors in the prostate gland using radical prostatectomy (RP) specimens as a reference method and to determine whether a correlation exists between F-PSMA-1007 uptake and the International Society of Urological Pathology (ISUP) grade and prostate specific antigen (PSA) levels at diagnosis. Thirty-nine patients referred for F-PSMA-1007 PET-CT for initial staging and who underwent RP within four months were retrospectively included. Read More

Anticancer Res 2021 Mar;41(3):1451-1458

Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.

Aim: To compare the diagnostic value of liver perfusion computed tomography (PCT) and biphasic contrast-enhanced CT (bpCECT) for detection and characterization of hepatocellular carcinoma (HCC), and to identify potential causes for inter-modal discrepancies.

Patients And Methods: In this retrospective study, 162 cases with a total of 325 HCC-typical lesions were evaluated using both PCT and bpCECT (mean time between examinations=15 days, range=0-13 days). HCC diagnosis was performed by multi-modality imaging including lesion growth at follow-up. Read More

Cureus 2021 Feb 23;13(2):e13502. Epub 2021 Feb 23.

Cardiology, St. John's Episcopal Hospital, New York, USA.

Imaging technology has diminished the reliance on cardiac auscultation as a definitive diagnostic tool. However, it retains relevance in its immediacy, minimal preparation, and power source independence. We present a case of clinically detected continuous murmur raising specific diagnostic possibilities not accounted for advanced imaging. Read More

J Neurosci Nurs 2021 Mar 29. Epub 2021 Mar 29.

Questions or comments about this article may be directed to Loretta J. Sutherly, MS BSN RN-BC SCRN NVRN CCRC, at L.J.S. is Stroke Program Manager, Emory University Hospital, Atlanta, GA. Jessica Wasserman, BSN RN SCRN, is Nurse Stroke Navigator, Grady Memorial Hospital, Atlanta, GA. Diogo C. Haussen, MD, is Associate Professor of Neurology, Emory University Hospital/Grady Memorial Hospital, Atlanta, GA.

Abstract: BACKGROUND: Carotid artery web may cause ischemic stroke and affects a vulnerable population of mostly younger patients. Multiple treatment options and lack of diagnostic consensus can cause confusion and reduce the likelihood to follow the recommended follow-up care. METHODS: We reviewed relevant literature using the following keywords: carotid web, CW, risk factors, stroke, treatments, education, incidence, prevalence, diagnostics, and nursing care. Read More

Urol Ann 2020 Oct-Dec;12(4):341-346. Epub 2020 Oct 15.

Department of Urology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

Purpose: The purpose of the study is to assess the quality of transurethral resection of bladder tumors (TURBTs) performed by "senior" and "junior" urologists in terms of detrusor muscle (DM) presence at the initial resection and presence of missed and residual tumors at second-look TURBT.

Patients And Methods: An analytic prospective cohort study included 171 patients with stage T1 and Ta bladder cancer who had undergone an initial TURBT. Patients were divided into two groups according to surgeon experience. Read More

EJNMMI Phys 2021 Mar 25;8(1):32. Epub 2021 Mar 25.

Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Background: [F]-fluorodeoxyglucose (FDG) positron emission tomography with computed tomography (PET-CT) is a well-established modality in the work-up of patients with suspected or confirmed diagnosis of lung cancer. Recent research efforts have focused on extracting theragnostic and textural information from manually indicated lung lesions. Both semi-automatic and fully automatic use of artificial intelligence (AI) to localise and classify FDG-avid foci has been demonstrated. Read More

Med Phys 2021 Mar 24. Epub 2021 Mar 24.

Department of Radiology, Stanford University School of Medicine, Stanford, CA, 94305.

Purpose: While multi-parametric Magnetic Resonance Imaging (MRI) shows great promise in assisting with prostate cancer diagnosis and localization, subtle differences in appearance between cancer and normal tissue lead to many false positive and false negative interpretations by radiologists. We sought to automatically detect aggressive cancer (Gleason pattern ≥ 4) and indolent cancer (Gleason pattern 3) on a per-pixel basis on MRI to facilitate the targeting of aggressive cancer during biopsy.

Methods: We created the Stanford Prostate Cancer Network (SPCNet), a convolutional neural network model, trained to distinguish between aggressive cancer, indolent cancer, and normal tissue on MRI. Read More

Arch Ital Urol Androl 2021 Mar 22;93(1):88-91. Epub 2021 Mar 22.

Azienda Ospedaliera Ospedali Riuniti Marche Nord, Division of Urology, Pesaro.

Aim: The upgrading or staging in men with prostate cancer (PCA) undergoing active surveillance (AS), defined as Gleason score (GS) ≥ 3+4 or more than 2 area with cancer, was investigated in our experience using the software-based fusion biopsy (FB).

Methods: We selected from our database, composed of 620 biopsies, only men on AS according to criteria of John Hopkins Protocol (T1c, < 3 positive cores, GS = 3+3 = 6). Monitoring consisted of PSA measurement every 3 months, a clinical examination every 6 months, confirmatory FB within 6 months and then annual FB in all men. Read More

Niger J Clin Pract 2021 Mar;24(3):446-451

Department of Preventive Dentistry,, Gynaeconology and Perinatology, Obafemi Awolowo University Teaching Hospital, Ile Ife, Nigeria.

Choricarcinoma co-existing with pregnancy is rare often misdiagnosed with great potential for hemorrhagic complications and death. We present a case of a 34-year-old woman diagnosed with choriocarcinoma in her 3 pregnancy with vaginal and pulmonary metastasis. Her first episode of vaginal bleeding was in the third trimester which was misdiagnosed. Read More

Cochrane Database Syst Rev 2021 03 15;3:CD014545. Epub 2021 Mar 15.

Division of Dentistry, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

Background: The detection and diagnosis of caries at the earliest opportunity is fundamental to the preservation of tooth tissue and maintenance of oral health. Radiographs have traditionally been used to supplement the conventional visual-tactile clinical examination. Accurate, timely detection and diagnosis of early signs of disease could afford patients the opportunity of less invasive treatment with less destruction of tooth tissue, reduce the need for treatment with aerosol-generating procedures, and potentially result in a reduced cost of care to the patient and to healthcare services. Read More

J Orthop Case Rep 2020 Nov;10(8):88-92

Department of Orthopaedic Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Introduction: Chronic posterior dislocation is a very rare injury. Various methods have been described for its treatment. This report describes a rare case of post-traumatic chronic posterior dislocation of the shoulder. Read More

J Orthop Case Rep 2020 Nov;10(8):84-87

Department of Orthopaedic Surgery, Michigan State University, East Lansing, MI 48824, USA.

Introduction: The following report describes a rare case of giant cell tumor (GCT) of the bone that presented in the distal phalanx of the thumb. GCT of the bone is a relatively rare, and typically benign condition that presents most frequently in the metaphysis of long bones in women age 30-50 years old. There are only three other instances in the literature describing GCT of the bone presenting in the distal phalanx of the thumb. Read More

Asian J Neurosurg 2020 Oct-Dec;15(4):1037-1040. Epub 2020 Oct 19.

Department of Pathology and Lab Medicine, AIIMS, Bhubaneswar, Odisha, India.

Osteoid osteoma (OO) affecting the spine is one of the common causes of painful scoliosis in the growing age group. The involvement is usually in the posterior elements involving the lumbar and cervical spine. We report a case of OO affecting the body of the thoracic vertebral body. Read More

Eur J Radiol 2021 Mar 4;138:109624. Epub 2021 Mar 4.

Department of Ultrasound, Peking University Third Hospital, Beijing 10091, China.

Purpose: To determine whether adding an artificial intelligence (AI) system to breast ultrasound (US) can reduce unnecessary biopsies.

Methods: Conventional US and AI analyses were prospectively performed on 173 suspicious breast lesions before US-guided core needle biopsy or vacuum-assisted excision. Conventional US images were retrospectively reviewed according to the BI-RADS 2013 lexicon and categories. Read More

Endoscopy 2021 Mar 5. Epub 2021 Mar 5.

North Tees and Hartlepool NHS Foundation Trust, Gastroenterology, Stockton on Tees, United Kingdom of Great Britain and Northern Ireland.

Background & Aims: Colorectal cancer (CRC) diagnosed following a cancer-negative colonoscopy is termed Post-Colonoscopy CRC (PCCRC). The World Endoscopy Organisation (WEO) recommends review of individual PCCRC cases, including categorisation into interval/non-interval CRCs, and root cause analysis to determine most plausible explanation. We aimed to test the usability, reproducibility, and outcomes of the WEO algorithms. Read More

Asia Pac J Sports Med Arthrosc Rehabil Technol 2021 Apr 13;24:23-28. Epub 2021 Feb 13.

Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikatacho, Kitaku, Okayama, 700-8558, Japan.

Background: Medial meniscus (MM) tears are associated with both acute and chronic anterior cruciate ligament (ACL) insufficiency and can lead to degenerative changes in the knee. ACL reconstruction (ACLR) combined with the meniscal repair was reported to result in decreased anterior knee joint laxity with evidence of improved patient-reported outcomes in the long term. However, a subtle tear of the MM posterior segment, also known as a ramp lesion, is difficult to detect on conventional magnetic resonance imaging (MRI) and is frequently missed in ACL-deficient knees. Read More

Arthrosc Tech 2021 Feb 16;10(2):e551-e554. Epub 2021 Jan 16.

Centre Orthopédique Santy, Lyon.

The associated lesion of the posterior oblique ligament (POL) in the setting of anterior cruciate ligament rupture is quite frequent due to the same rotational mechanism. The diagnosis of POL lesions is challenging, and physical examination is delicate; moreover, they can be easily missed on magnetic resonance imaging. Once recognized, POL lesions must be repaired to restore posteromedial corner kinematics. Read More

J Healthc Eng 2021 22;2021:6667046. Epub 2021 Feb 22.

Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Orthopedics Department, Hangzhou 310006, Zhejiang, China.

Arthroscopy is the gold standard for diagnosing ACL injuries. It is a dual clinical technique for examination and treatment, which can effectively target the injury site for repair and treatment and can also accurately identify the lesion site and determine the degree of ligament injury through visual and three-dimensional observation of ligament injuries that are difficult to detect on imaging. However, this technique is invasive, so the clinic still needs to improve the related auxiliary imaging examination. Read More

J UOEH 2021 ;43(1):75-80

The Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.

A 13-year-old boy was admitted to our hospital because of bloody stools. Although a Meckel's diverticulum (MD) was suspected, capsule endoscopy (CE) revealed no remarkable findings. Seven months later, he was admitted again because of rebleeding. Read More

JPRAS Open 2021 Jun 22;28:29-32. Epub 2021 Jan 22.

Mersey Regional Plastic Surgery and Burns Service, Whiston Hospital, Liverpool, UK.

Case Report: A 76-year-old Caucasian woman with a history of previous BCCs excised from the head and legs was referred from the dermatology team with a biopsy proven superficial BCC to the left palm. The patient had presented to the dermatology team with the same lesion 7 years prior to the definitive diagnosis. The lesion was described as 27 × 15 mm scaly, poorly-defined, plaque-like lesion to the central palm. Read More

Adv Med Sci 2021 Feb 25;66(1):170-175. Epub 2021 Feb 25.

Endoterapia, H-T. Centrum Medyczne, Tychy, Poland; Department of Gastroenterology and Hepatology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

Purpose: Heterotopic gastric mucosa in the upper esophagus (cervical inlet patches - CIP) may be easily missed during esophagogastroduodenoscopy (EGD) due to low awareness of this usually, but not invariably, benign lesion. Narrow-band imaging (NBI) emphasizes contrast between normal esophageal mucosa and CIP. The purpose of this study was to investigate how NBI use and enhanced attention of operator during inspection of upper esophagus impacts cervical inlet patch detection rate (CIPDR). Read More

Clin Exp Dermatol 2021 Feb 27. Epub 2021 Feb 27.

Department of Dermatology, South Infirmary Victoria University Hospital, Cork, Ireland.

Full skin examination (FSE) may improve the detection of malignant melanoma (MM). The objective of this study was to assess the safety of targeted lesion examination (TLE) compared with FSE in our Pigmented Lesion Clinic (PLC). Patients attending the PLC were randomized in a 2 : 1 ratio to FSE (intervention) or TLE (standard care). Read More

J Med Virol 2021 Feb 25. Epub 2021 Feb 25.

Department of Obstetrics and Gynecology, Kanazawa Medical University, Uchinada, Japan.

The Aptima human papillomavirus (HPV) test (APTIMA) detects E6-E7 mRNA in abnormal cells in the uterine cervix. To investigate the accuracy of APTIMA for cervical cancer screening in Japan, 423 subjects, mostly referrals with abnormal cytology or being followed up for cervical intraepithelial neoplasia (CIN)1, were screened using two HPV tests, hybrid capture 2 (HC2) and APTIMA, and by the Pap test. Colposcopy was conducted in all subjects with a positive result in either test type. Read More