Epilepsy Res 2021 Mar 18;171:106562. Epub 2021 Jan 18.
Krembil Research Institute, University Health Network, Toronto, ON, Canada; Division of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Background: Mesial temporal sclerosis (MTS) is the most common cause of temporal lobe epilepsy (TLE). While MTS is associated with a high cure rate after temporal lobectomy (TL), postoperative neurocognitive deficits are common, and a subset of patients may continue to have refractory seizures.
Objective: To use magnetic resonance (MR) volumetry to identify features of the mesial temporal lobe in patients with MTS that correlate with seizure and neurocognitive outcome after temporal lobectomy. Read More