643 results match your criteria lead avr

Lead aVR predicts early revascularization but not long-term events in patients referred for stress electrocardiography.

PLoS One 2021 8;16(4):e0249779. Epub 2021 Apr 8.

Division of Cardiovascular Medicine, Department of Medicine, The Cardiovascular Imaging Center, University of Virginia Health System, Charlottesville, VA, United States of America.

Background: Exercise stress electrocardiography (ExECG) is recommended as a first-line tool to assess ischemia, but standard ST-analysis has limited diagnostic accuracy. ST elevation in lead aVR has been associated with left main and LAD disease in the population undergoing coronary angiography but has not been studied in the general population undergoing stress testing for the initial evaluation of CAD without coronary angiography. We sought to determine the predictive value of lead aVR elevation for ischemia, early revascularization, and subsequent cardiac events in consecutive patients undergoing ExECG. Read More

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Rapid-deployment aortic valve replacement in high-risk patients: A case-control study.

J Cardiovasc Thorac Res 2021 30;13(1):23-27. Epub 2021 Jan 30.

Department of Cardiovascular, University Hospital of Clermont-Ferrand, France.

Aortic valve stenosis is the most frequent cardiac valve pathology in the western world. In high-risk patients, conventional aortic valve replacement (C-AVR) carries high rates of morbidity and mortality. In the last few years, rapid-deployment valves (RDV) have been developed to reduce the surgical risks. Read More

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January 2021

T-wave peak-end interval and ratio of T-wave peak-end and QT intervals: novel arrhythmogenic and survival markers for dogs with myxomatous mitral valve disease.

J Vet Cardiol 2021 Feb 27;35:25-41. Epub 2021 Feb 27.

Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, PR, 80035-050, Brazil.

Introduction/objectives: In the past few years, novel markers such as the interval between the peak and the end of T-wave (Tpte) and Tpte/QT ratio have been shown to have high sensitivity for ventricular arrhythmias and mortality. We analyzed these and other parameters of ventricular repolarization, such as QT interval, QT interval corrected for heart rate (QTc), and QT dispersion (QTd) in dogs with myxomatous mitral valve disease (MMVD). Additionally, we investigated their relationship with the progression of the disease, echocardiographic parameters, and ventricular arrhythmias and assessed their prognostic value with development of clinical signs or mortality as the final outcome. Read More

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February 2021

Natural history and outcomes of non-replaced aortic sinuses in patients with bicuspid aortic valves.

Ann Thorac Surg 2021 Mar 31. Epub 2021 Mar 31.

Department of Cardiovascular Surgery, Mayo Clinic, Rochester.

Background: Enlargement of the sinus of Valsalva (SOV) is common in patients with bicuspid aortic valves (BAV), and management at the time of aortic valve replacement (AVR) and concomitant ascending aorta replacement/repair is controversial.

Methods: Between January 2000 and July 2017, 400 patients with BAV underwent AVR and concomitant ascending aorta repair (79%, graft replacement; 21%, aortoplasty). To assess the impact of the initial SOV dimension on future dilatation and outcomes, patients were stratified into two groups: SOV<40mm (n=209) and SOV≥40mm (n=191). Read More

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Small Immunomodulatory Molecules as Potential Therapeutics in Experimental Murine Models of Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS).

Int J Mol Sci 2021 Mar 4;22(5). Epub 2021 Mar 4.

Division of Neonatology, Department of Pediatrics, Drexel University, Philadelphia, PA 19197, USA.

Background: Acute lung injury (ALI) or its most advanced form, acute respiratory distress syndrome (ARDS) is a severe inflammatory pulmonary process triggered by a variety of insults including sepsis, viral or bacterial pneumonia, and mechanical ventilator-induced trauma. Currently, there are no effective therapies available for ARDS. We have recently reported that a novel small molecule AVR-25 derived from chitin molecule (a long-chain polymer of N-acetylglucosamine) showed anti-inflammatory effects in the lungs. Read More

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Aortic Root Enlargement in patients with small aortic annulus undergoing double valve replacement. Is it justified? A retrospective Comparative cohort study.

Heart Surg Forum 2021 01 13;24(1). Epub 2021 Jan 13.

Department of Cardiothoracic Surgery, Cairo University, Cairo, Egypt.

Background: Small Aortic Annulus (AA) is big issue during Aortic Valve Replacement (AVR) necessitating replacement of an undersized prosthetic valve especially with Double Valve Replacement (DVR). Despite that small aortic valve prostheses can lead to Prosthesis-Patient Mismatch (PPM), there remains reluctance to perform aortic root enlargement (ARE) procedures fearing from morbidity and mortality.

Objective: To evaluate clinical and echocardiographic outcomes in patients with small aortic annulus undergoing double valve replacement. Read More

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January 2021

[Swedish ECG presentation is logical and easily understood].

Lakartidningen 2021 02 4;118. Epub 2021 Feb 4.

kardiolog, Svenska Kardiologföreningen.

During four decades, the ECG limb lead display has differed between Sweden and the rest of the world. In the classical, or international, display, the limb leads are presented in two groups in non-contiguous order: I, II, III, and aVR, aVL, aVF. When ECG recording and presentation was standardized in Sweden, a joint decision between several medical specialty associations was made to use the so-called Cabrera presentation, in which limb leads are presented in contiguous order: aVL, I, -aVR, II, aVF and III. Read More

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February 2021

Ventricular Tachycardia with ST Elevation in Lead aVR Associated with Normal Coronary Arteries: A Case Report and Review of Literature.

Am J Med Case Rep 2021 14;9(3):201-205. Epub 2021 Jan 14.

Department of Internal Medicine, State University of New York, Downstate Health Sciences University, Brooklyn, NY 11203, U.S.A.

As per the 2013 guidelines of ACCF/AHA (American College of Cardiology Foundation/American Heart Association), ST Elevation (STE) in lead augmented vector right (aVR), along with ST depression in multiple leads, is associated with critical stenosis of left main coronary artery (LMCA), left anterior descending artery (LAD) or a triple vessel disease (TVD). Early identification of ST-Elevation Myocardial Infarction (STEMI) is important as timely reperfusion with intervention can save myocardium and improve survival. We present a case of a 70 years old female, with cardiovascular risk factors, who presented to the emergency department with chest pain decompensating with ventricular tachycardia. Read More

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January 2021

Mitral Regurgitation in Patients With Coexisting Chronic Aortic Regurgitation: An Evidence-Based Narrative Review.

J Cardiothorac Vasc Anesth 2021 Jan 8. Epub 2021 Jan 8.

Wayne State University School of Medicine, St. Joseph Mercy Oakland Medical Office Building, Pontiac, MI.

Chronic aortic regurgitation (AR) frequently leads to significant downstream changes to the left ventricle and pulmonary vasculature; these structural and physiologic changes result in lower- than expected patient survival. Progressive, uncorrected AR can lead to left ventricle dilation and subsequent mitral valve leaflet tethering, as well as mitral annular dilation, resulting in secondary mitral regurgitation (MR) in up to 45% of patients. Surgical aortic valve replacement (AVR) improves secondary MR in most patients, but survival is significantly lower in those patients who do not show improvement in MR after AVR. Read More

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January 2021

Extrinsic compression of the left main coronary artery: A rare cause of cardiogenic shock.

Radiol Case Rep 2021 Mar 14;16(3):714-717. Epub 2021 Jan 14.

Department of Cardiology, National Hospital Organization Nagoya Medical Center, 4-1-1, Sannomaru, Naka-ku Nagoya-shi, Aichi 460-0001, Japan.

A left main coronary artery (LMCA) stenosis due to extrinsic compression by mediastinal tumor is a rare finding. In this case reports, we present a 63-year-old woman, who was transferred to the emergency department with chief complains of persistent chest and back pain. An electrocardiogram revealed diffuse ST-segment depression (elevation in lead aVR). Read More

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The Reconstruction of a 12-Lead Electrocardiogram from a Reduced Lead Set Using a Focus Time-Delay Neural Network.

Acta Cardiol Sin 2021 Jan;37(1):47-57

Biomedical Engineering Research Group, Department of Mechanical and Mechatronic Engineering, Stellenbosch University, South Africa.

Background: The 12-lead electrocardiogram (ECG) is the gold-standard ECG method used by cardiologists. However, accurate electrode placement is difficult and time consuming, and can lead to incorrect interpretation.

Objectives: The objective of this study was to accurately reconstruct a full 12-lead ECG from a reduced lead set. Read More

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January 2021

A Systematic Approach to Evaluate Patients Presenting With ST-Segment Elevation in Lead aVR: A Case Series.

Cureus 2020 Nov 30;12(11):e11800. Epub 2020 Nov 30.

Cardiology, New York Presbyterian Queens, New York, USA.

ST-segment elevation (STE) in the lead aVR indicates global ischemia of the myocardium and is often associated with obstructive coronary artery disease (CAD). We report a serial of cases presenting with STE in aVR and diffuse ST depressions in more than six other leads as a common feature, but of different etiologies, i.e. Read More

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November 2020

Creating 12-lead electrocardiogram waveforms using a three-lead bedside monitor to ensure appropriate monitoring.

J Arrhythm 2020 Dec 5;36(6):1107-1108. Epub 2020 Oct 5.

Division of Cardiology, Department of Internal Medicine St. Marianna University School of Medicine Kawasaki Kanagawa Japan.

How do you place the three electrodes to create waveforms for leads I, II, III, aVR, aVL, aVF, and V1-V6? Read More

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December 2020

Association between P wave polarity in atrial premature complexes and cardiovascular events in a community-dwelling population.

BMJ Open 2020 11 4;10(11):e033553. Epub 2020 Nov 4.

Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.

Objective: To examine the association between polarity of atrial premature complexes (APCs) and stroke.

Design: A prospective study.

Setting And Participants: A total of 11 092 participants in the Jichi Medical School cohort study were included after excluding patients with atrial fibrillation. Read More

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November 2020

Conduction disorders after aortic valve replacement with rapid-deployment bioprostheses: early occurrence and one-year evolution.

Ann Cardiothorac Surg 2020 Sep;9(5):396-407

Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.

Background: Rapid-deployment bioprostheses represent one of the newest aortic valve substitutes introduced into clinical practice. The aim of this retrospective single-center study was to evaluate the occurrence of conduction disorders (CDs) after rapid-deployment aortic valve implantation at discharge and at 1-year follow-up, and to identify risk factors for CDs and permanent pacemaker implantation (PPI).

Methods: All patients who reached 1-year follow-up after isolated or combined aortic valve replacement (AVR) with rapid-deployment bioprostheses (Intuity Elite, Edwards Lifesciences, Irvine, CA) at our institution were included in this study. Read More

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September 2020

Avoiding misdiagnosis of arrhythmogenic cardiomyopathy by a simple look at lead aVR.

Stefan Peters

Europace 2021 Apr;23(4):651

Head of Cardiological Department, Internal Medicine, Hospital of Wernigerode, Ilsenburger Str. 15, 38855 Wernigerode, Germany.

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Host Plant Strategies to Combat Against Viruses Effector Proteins.

Curr Genomics 2020 Sep;21(6):401-410

1Department of Biotechnology, Vigyan Bhawan - Block B, New Campus, Mohanlal Sukhadia University, Udaipur, Rajasthan - 313001, India; 2Department of Biotechnology, Deen Dayal Upadhyay Gorakhpur University, Gorakhpur, Uttar Pradesh - 273009, India.

Viruses are obligate parasites that exist in an inactive state until they enter the host body. Upon entry, viruses become active and start replicating by using the host cell machinery. All plant viruses can augment their transmission, thus powering their detrimental effects on the host plant. Read More

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September 2020

Prognostic implications of ST-segment elevation in lead aVR in patients with acute coronary syndrome: A meta-analysis.

Ann Noninvasive Electrocardiol 2021 01 15;26(1):e12811. Epub 2020 Oct 15.

Department of Cardiology, Gansu Provincial Hospital, Lanzhou, China.

Background: ST-segment elevation (STE) in lead aVR is a useful tool in recognizing patients with left main or left anterior descending coronary obstruction during acute coronary syndrome (ACS). The prognostic implication of STE in lead aVR on outcomes has not been established.

Methods: We performed a systematic search for clinical studies about STE in lead aVR in four databases including PubMed, EMBASE, Cochrane Library, and Web of Science. Read More

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January 2021

A new method to determine the QRS axis-QRS axis determination.

Clin Cardiol 2020 Dec 6;43(12):1534-1538. Epub 2020 Oct 6.

Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, PR China.

Background: The development of a perfect method for determining the mean QRS axis (ÂQRS) is still lacking.

Hypothesis: We proposed a new simple method, whether this method is accurate is unknown.

Methods: The axis perpendicular to the mean QRS axis (P-ÂQRS) divides six limb leads into two groups. Read More

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December 2020

A Ghost in Coronary Artery - Coronary Artery Embolism After Discontinuation of Rivaroxaban in a Patient With Atrial Fibrillation: Case Report and Review of Literature.

Cureus 2020 Aug 27;12(8):e10082. Epub 2020 Aug 27.

Cardiovascular Disease, Lower Bucks Hospital, Bristol, USA.

Coronary artery embolism (CAE) is a rare clinical entity that can cause acute myocardial infarction (AMI). The exact prevalence of coronary artery embolism is unknown. CAE was found to be associated with conditions that can lead to thrombo-embolism, including infective endocarditis, atrial fibrillation, mitral valve disease, valve surgery. Read More

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Effects of upright T-wave in lead aVR on left ventricular volume and function derived from ECG-gated SPECT in patients with advanced chronic kidney disease.

Ann Nucl Med 2021 Jan 27;35(1):1-7. Epub 2020 Sep 27.

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3, Kasumi-cho, Minami-ku, Hiroshima, 734-8551, Japan.

Background: Numerous studies have shown the association between chronic kidney disease (CKD) and adverse cardiac events. We investigated whether or not the upright T-wave in lead aVR (TaVR) could predict left ventricular (LV) volume and function derived from ECG-gated SPECT in patients with advanced CKD.

Methods: Two hundred and sixty-one patients with advanced CKD [estimated glomerular filtration rate (eGFR) < 45 ml/min/1. Read More

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January 2021

Hypo-attenuated leaflet thickening and reduced leaflet motion after the implantation of the Perceval S sutureless bioprosthesis.

J Artif Organs 2020 Sep 21. Epub 2020 Sep 21.

Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.

Hypo-attenuated leaflet thickening (HALT) is gaining attention as a relatively common issue after surgical or transcatheter aortic valve replacement (AVR). However, only a few reports have described HALT in sutureless bioprosthesis, which has emerged as a promising tool with excellent hemodynamics and enhanced implantability. We herein report a 75-year-old woman who underwent quintuple coronary artery bypass grafting and sutureless AVR with a Perceval S bioprosthesis (LivaNova PLC, London, UK). Read More

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September 2020

Wide QRS Complex Tachycardia With a Dominant R-Wave in Lead aVR-Is It Ventricular Tachycardia?

JAMA Intern Med 2020 Sep 21. Epub 2020 Sep 21.

The first affiliated hospital of Hunan normal university, Hunan Provincial People's Hospital, Changsha City, Hunan Province, Changsha, China.

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September 2020

Long-term outcome of pre-specified ECG patterns in acute coronary syndrome.

J Electrocardiol 2020 Sep - Oct;62:178-183. Epub 2020 Aug 8.

Faculty of Medicine and Health Technology, Tampere University, Finland; Heart Center, Department of Cardiology, Tampere University Hospital, Finland.

Background: Long-term outcome of real-life acute coronary syndrome (ACS) patients with selected ECG patterns is not well known.

Purpose: To survey the 10-year outcome of pre-specified ECG patterns in ACS patients admitted to a university hospital.

Methods: A total of 1184 consecutive acute coronary syndrome patients in 2002-2003 were included and followed up for 10 years. Read More

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Is isolated ST segment elevation in Lead aVR associated with high grade coronary artery disease?

J Electrocardiol 2020 Sep - Oct;62:170-177. Epub 2020 Sep 8.

Department of Medicine, Division of Cardiovascular Disease and Hypertension, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States. Electronic address:

Background: The diagnostic accuracy of lead aVR ST-segment elevation for left main or triple vessel disease (LM/3VD) has not been universally accepted. In the present analysis we sought to evaluate the diagnostic accuracy of STEaVR in patients presenting with an acute coronary syndrome (ACS).

Methods: Pooled sensitivity, specificity, positive, and negative likelihood ratios were calculated using a random effects model (DerSimonian-Laird Method) for computing summary estimates and receiver operator curve (ROC) analysis for evaluating overall diagnostic accuracy. Read More

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September 2020

Low rate of life-threatening events and limitations in predicting invasive and noninvasive markers of symptoms in a cohort of type 1 Brugada syndrome patients: Data and insights from the GenBra registry.

J Cardiovasc Electrophysiol 2020 11 5;31(11):2920-2928. Epub 2020 Oct 5.

Instituto do Coração (InCor), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

Background: Brugada syndrome (BrS) has diagnostic challenges and controversial risk assessment. We aimed to investigate invasive and noninvasive parameters in symptomatic and asymptomatic patients from a Brazilian cohort of type-1 BrS.

Methods: Patients with spontaneous and drug-induced type-1 BrS were classified into two groups, asymptomatic (n = 116, 84. Read More

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November 2020

Protected Percutaneous Coronary Intervention (PCI) of Cabrol Type Anastomosis of Saphenous Vein Graft (SVG) to the Left Main Coronary Artery (LMCA).

Cureus 2020 Jun 25;12(6):e8829. Epub 2020 Jun 25.

Cardiology, Maimonides Medical Center, Brooklyn, USA.

The use of percutaneous left ventricular assist devices (VAD) may minimize the risk of hemodynamic compromise during such high-risk percutaneous coronary intervention (PCI) and allow complete revascularization, thus improving outcomes. A good understanding of cardiac hemodynamics is essential in making informed decisions during such cases. A 61-year-old male with an extensive surgical cardiac history including a modified Cabrol type anastomosis with saphenous vein (SVG) conduits to two coronary arteries presented to our hospital with severe substernal chest discomfort and was noted to have diffuse ST depressions along with subtle ST elevations in lead aVR suggestive of diffuse sub-endocardial ischemia. Read More

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Routine Placement of Temporary Epicardial Pacing Leads Is Not Required After Minimally Invasive Aortic Valve Replacement.

Innovations (Phila) 2020 Jul/Aug;15(4):355-360. Epub 2020 Jul 23.

6923 Division of Cardiac Surgery, University of Rochester Medical Center, NY, USA.

Objective: Our objective is to identify the incidence of urgent transvenous (TV) pacing wire placement following minimally invasive aortic valve replacement (mini-AVR).

Methods: This is a single-center, retrospective, observational study including 359 individuals who underwent isolated mini-AVR through right anterior mini-thoracotomy between January 2015 and September 2019. Patients were grouped according to avoidance or insertion of epicardial pacing wires, and further subdivided based on the requirement for postoperative emergent temporary TV pacing or permanent pacemaker (PPM) placement during the index admission. Read More

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Effector Repertoire of : In Search of Possible Virulence Factors Responsible for Its Host Specificity.

Front Genet 2020 9;11:579. Epub 2020 Jun 9.

Laboratorio de Micología y Fitopatología, Facultad de Ingeniería, Universidad de los Andes, Colombia, Bogota.

is an oomycete plant pathogen closely related to It infects tree tomato () in northern South America, but is, under natural conditions, unable to infect potatoes or tomatoes, the main hosts of its sister species . We characterized, and compared the effector repertoires of and other species. To this end, we used approaches to predict and describe the repertoire of secreted proteins in species and determine unique and core effectors. Read More

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