5,478 results match your criteria latency surveillance

Association of Depressive Symptoms with Sleep Disturbance: A Co-twin Control Study.

Ann Behav Med 2021 May 15. Epub 2021 May 15.

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

Background: Few studies have comprehensively evaluated the association of depression with sleep disturbance using a controlled twin study design.

Purpose: To cross-sectionally evaluate the association of depression with both objective and subjective sleep disturbance.

Methods: We studied 246 members of the Vietnam Era Twin Registry. Read More

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Untargeted metabolomics of newborn dried blood spots reveals sex-specific associations with pediatric acute myeloid leukemia.

Leuk Res 2021 Apr 24;106:106585. Epub 2021 Apr 24.

Center for Integrative Research on Childhood Leukemia and the Environment, University of California, Berkeley, CA, 94720, USA; Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, 94720, USA.

The etiology of pediatric acute myeloid leukemia (AML) is largely unknown, but evidence for mutations in utero and long latency periods suggests that environmental factors play a role. Therefore, we used untargeted metabolomics of archived newborn dried blood spots (DBS) to investigate neonatal exposures as potential causal risk factors for AML. Untargeted metabolomics profiling was performed on DBS punches from 48 pediatric patients with AML and 46 healthy controls as part of the California Childhood Leukemia Study (CCLS). Read More

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Incidence, characteristics and risk factors for drug-induced liver injury in hospitalized patients: A matched case-control study.

Br J Clin Pharmacol 2021 May 4. Epub 2021 May 4.

Pharmacy Department, Medical Security Center, Chinese People's Liberation Army General Hospital, Beijing, China.

Aims: The diagnosis of drug-induced liver injury (DILI) is relatively complex and involves a wide variety of drugs. The purpose of this study was to use algorithms to quickly screen DILI patients, determine its incidence and identify risk factors.

Methods: The Adverse Drug Events Active Surveillance and Assessment System-2 was used to extract the data of patients hospitalized in 2019 according to the set standards and the Roussel Uclaf Causality Assessment Method was used to evaluate patients who met the standards. Read More

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Factors Influencing Sleep Quality among Female Staff Nurses during the Early COVID-19 Pandemic in the United States.

Int J Environ Res Public Health 2021 Apr 30;18(9). Epub 2021 Apr 30.

School of Nursing, University of Virginia, 225 Jeanette Lancaster Way, Charlottesville, VA 22903, USA.

This study aimed to assess the overall level of sleep quality among female staff nurses in the United States during the early COVID-19 pandemic. It also aimed to examine factors associated with sleep quality and its seven subcomponents: subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbance, use of sleeping medications, and daytime dysfunction. A descriptive, correlational, and cross-sectional study design was used. Read More

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Quantitative standardization of resident mouse behavior for studies of aggression and social defeat.

Neuropsychopharmacology 2021 May 3. Epub 2021 May 3.

Neuroscience Program, Michigan State University, East Lansing, MI, USA.

Territorial reactive aggression in mice is used to study the biology of aggression-related behavior and is also a critical component of procedures used to study mood disorders, such as chronic social defeat stress. However, quantifying mouse aggression in a systematic, representative, and easily adoptable way that allows direct comparison between cohorts within or between studies remains a challenge. Here, we propose a structural equation modeling approach to quantify aggression observed during the resident-intruder procedure. Read More

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History of Weight Cycling Is Prospectively Associated With Shorter and Poorer-Quality Sleep and Higher Sleep Apnea Risk in Diverse US Women.

J Cardiovasc Nurs 2021 Apr 30. Epub 2021 Apr 30.

Vivian Cao, MS Graduate Student, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, New York. Nour Makarem, PhD Assistant Professor of Epidemiology, Mailman School of Public Health, Department of Epidemiology, Columbia University Irving Medical Center, New York, New York. Moorea Maguire, MS Graduate Student, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, New York. Ivan Samayoa, MS Graduate Student, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, New York. Huaqing Xi, MS Graduate Student, Department of Biostatistics, Columbia University Irving Medical Center, New York, New York. Citina Liang, MA Graduate Student, Department of Statistics, Graduate School of Arts and Science, Columbia University, New York, New York. Brooke Aggarwal, EdD, MS, FAHA Assistant Professor of Medical Sciences, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, and Department of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, New York.

Background: Poor sleep and history of weight cycling (HWC) are associated with worse cardiovascular health, yet limited research has evaluated the association between HWC and poor sleep patterns.

Methods: The American Heart Association Go Red for Women Strategically Focused Research Network cohort at Columbia University (n = 506; mean age, 37 ± 15.7 years; 61% racial/ethnic minority) was used to evaluate the cross-sectional associations of HWC and sleep at baseline and the prospective associations of HWC from baseline with sleep at the 1-year visit. Read More

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The relationship among primary anatomic subsite and risk and distribution of second malignant neoplasms in patients with stage I/II diffuse large B-cell lymphoma: An analysis of the surveillance, epidemiology, and end results database.

Transl Oncol 2021 Apr 28;14(7):101106. Epub 2021 Apr 28.

Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Collaborative Innovation Center of Hematology, Huazhong University of Science and Technology, Wuhan, China.

Background: Recent studies have reported that diffuse large B-cell lymphoma (DLBCL) involving different primary extranodal sites have distinct clinicopathological characteristics and prognosis. However, the risk of secondary malignant neoplasms (SMNs) in DLBCL survivors with different primary extranodal sites are unknown.

Methods: A total of 40,714 patients diagnosed with stage I/II DLBCL were included from the Surveillance, Epidemiology, and End Results (SEER) database from 1983 to 2015. Read More

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Autonomous Marine Robot Based on AI Recognition for Permanent Surveillance in Marine Protected Areas.

Sensors (Basel) 2021 Apr 10;21(8). Epub 2021 Apr 10.

Laboratory of Information and Communication Technologies (LabTIC), National School of Applied Sciences, Abdelmalek Essaadi University, ENSA of Tangier, Route Ziaten, Tangier BP 1818, Morocco.

The world's oceans are one of the most valuable sources of biodiversity and resources on the planet, although there are areas where the marine ecosystem is threatened by human activities. Marine protected areas (MPAs) are distinctive spaces protected by law due to their unique characteristics, such as being the habitat of endangered marine species. Even with this protection, there are still illegal activities such as poaching or anchoring that threaten the survival of different marine species. Read More

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Corticosteroids for COVID-19 Therapy: Potential Implications on Tuberculosis.

Int J Mol Sci 2021 Apr 6;22(7). Epub 2021 Apr 6.

Public Health Research Institute at New Jersey Medical School, Rutgers University, 225 Warren Street, Newark, NJ 08854, USA.

On 11 March 2020, the World Health Organization announced the Corona Virus Disease-2019 (COVID-19) as a global pandemic, which originated in China. At the host level, COVID-19, caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), affects the respiratory system, with the clinical symptoms ranging from mild to severe or critical illness that often requires hospitalization and oxygen support. There is no specific therapy for COVID-19, as is the case for any common viral disease except drugs to reduce the viral load and alleviate the inflammatory symptoms. Read More

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[The dynamics of sleep quality in patients with chronic insomnia during the complex spa treatment with the inclusion of transcranial magnetic therapy].

Vopr Kurortol Fizioter Lech Fiz Kult 2021 ;98(2):10-16

Altai State Medical University, Barnaul, Russia.

Dissatisfaction with night sleep occurs in 45% of the population. Chronic insomnia is one of the most common sleep disorders. The incidence of insomnia is estimated at 9-15%. Read More

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Risk and survival of second primary malignancies following diagnosis of gastric mucosa-associated lymphoid tissue lymphomas: A population-based study.

Curr Probl Cancer 2021 Apr 2:100735. Epub 2021 Apr 2.

Department of Gastroenterology, The First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou, 215006, Jiangsu, China. Electronic address:

Whether gastric mucosa-associated lymphoid tissue lymphoma (GML) is associated with a higher risk of second primary malignancy (SPM) remains controversial. This study aimed to evaluate the detailed risk of SPM and its prognosis in patients with GML based on a large population-based cohort. The Surveillance, Epidemiology, and End Results database was searched to identify patients who were diagnosed with GML during 2000-2014. Read More

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A case of delayed cyst formation post brain AVM stereotactic radiosurgery for arteriovenous malformation: Case report.

J Clin Neurosci 2021 May 4;87:17-19. Epub 2021 Mar 4.

Royal Brisbane and Women Hospital, Queensland, Australia. Electronic address:

Arteriovenous malformations (AVMs) are a rare cause of cerebrovascular abnormality with incidence of about 1 in 100,000 people per year and point prevalence of about 0.2%. AVMs are associated with serious complications such as intracranial haemorrhage (2-4% a year, 16% and 29% at 10 and 20 years after diagnosis), seizures (10-30%), focal neurologic deficits, and headaches. Read More

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Causes of Death After Colorectal Cancer Diagnosis: A Population-Based Study.

Front Oncol 2021 30;11:647179. Epub 2021 Mar 30.

Department of Medical Oncology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

Non-cancer causes of death in patients with colorectal cancer (CRC) have not received much attention until now. The purpose of the current study is to investigate the non-cancer causes of death in patients with CRC at different periods of latency. Eligible patients with CRC were included from the Surveillance, Epidemiology, and End Results (SEER) database, and standardized mortality ratios (SMRs) were calculated using the SEER*Stat software 8. Read More

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Excessive Daytime Sleepiness: A Clinical Review.

Mayo Clin Proc 2021 05 9;96(5):1288-1301. Epub 2021 Apr 9.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN; Center for Sleep Medicine, Mayo Clinic, Rochester, MN. Electronic address:

Excessive daytime sleepiness (EDS) is a highly prevalent condition that is associated with significant morbidity. The causes of EDS are varied, and include inadequate sleep, sleep disordered breathing, circadian rhythm sleep-wake disorders, and central disorders of hypersomnolence (narcolepsy, idiopathic hypersomnia, and Kleine-Levin syndrome). Additionally, EDS could represent a symptom of an underlying medical or psychiatric disorder. Read More

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Invasive Mucinous Adenocarcinomas With Spatially Separate Lung Lesions: Analysis of Clonal Relationship by Comparative Molecular Profiling.

J Thorac Oncol 2021 Apr 8. Epub 2021 Apr 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address:

Introduction: Pulmonary invasive mucinous adenocarcinomas (IMAs) often present with spatially separate lung lesions. Clonal relationship between such lesions, particularly those involving contralateral lobes, is not well established. Here, we used comparative genomic profiling to address this question. Read More

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Am J Obstet Gynecol MFM 2021 Apr 6:100371. Epub 2021 Apr 6.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH.

Background: A proposed benefit of cervical length (CL) assessment after 24 weeks' gestation in women with a prior history of preterm birth (PTB) is to aid in the timing of antenatal corticosteroids (ACS) in otherwise asymptomatic women.

Objective: We sought to investigate whether use of an ultrasonographic short CL as an indication for ACS in asymptomatic women results in optimal exposure when compared to women receiving ACS for preterm labor symptoms.

Study Design: Retrospective cohort study of all women with a prior spontaneous preterm birth and a singleton gestation who underwent serial CL assessment at a large academic tertiary medical center from 2011-2016. Read More

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Effects of High-Fructose Diet . Teklad Diet in the MNU-Induced Rat Mammary Cancer Model: Altered Tumorigenesis, Metabolomics and Tumor RNA Expression.

J Obes Chronic Dis 2021 11;5(1):67-78. Epub 2021 Jan 11.

Chemopreventive Agent Development Research Group, Division of Cancer Prevention, Rockville, MD.

Epidemiology, clinical and experimental animal studies suggest high fructose diets are detrimental to metabolic status and may contribute to tumor development. This due to increased obesity and metabolic syndrome, known risk factors for many types of cancer. We compared tumor development in N-methyl-N-nitrosourea (MNU)-treated rats fed either a high (60%)-fructose diet (HFD) or a standard diet (SD). Read More

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January 2021

Mucosal Kaposi's sarcoma in HIV-negative patients: a large case series from a single, tertiary referral center in Italy.

Int J Dermatol 2021 Apr 8. Epub 2021 Apr 8.

Dermatology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Background: Mucosal involvement in HIV-negative Kaposi's sarcoma (KS) is uncommon but has potentially serious repercussions on patient care. Evidence regarding its epidemiology and optimal management is limited. Invasive endoscopic staging at diagnosis and periodically during follow-up is currently recommended by major guidelines. Read More

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The role of EBV in hematolymphoid proliferations: Emerging concepts relevant to diagnosis and treatment.

Histopathology 2021 Apr 7. Epub 2021 Apr 7.

Robert J. Tomsich Pathology and Laboratory Medicine Institute, Department of Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA.

Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus with >90% of the adult population worldwide harboring latent infection. A small subset of those infected develop EBV-associated neoplasms including a range of lymphoproliferative disorders (LPD). The diagnostic distinction of these entities appears increasingly relevant as our understanding of EBV-host interactions and mechanisms of EBV-driven lymphomagenesis improves. Read More

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Second primary malignancies after ocular adnexal lymphoma diagnosis.

BMC Ophthalmol 2021 Apr 7;21(1):162. Epub 2021 Apr 7.

Baylor College of Medicine, Department of Ophthalmology-Cullen Eye Institute, 1977 Butler Boulevard, Houston, TX, 77030, USA.

Background: Although studies have investigated the risk of second primary malignancies (SPMs) associated with lymphoma of various sites, limited studies have investigated this risk in patients with lymphoma originating within the ocular adnexa. We conducted a retrospective study to assess incidence of secondary malignancies in patients with a prior diagnosis of ocular adnexal lymphoma (OAL) and to determine latency periods and age-groups at increased risk for SPM occurrence.

Methods: Retrospective analysis was performed on data obtained from Surveillance, Epidemiology, and End Results (SEER) 9 database. Read More

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Thresholds for carcinogens.

Chem Biol Interact 2021 May 3;341:109464. Epub 2021 Apr 3.

7 West Melrose Avenue, Baltimore, MD 21210, USA. Electronic address:

Current regulatory cancer risk assessment principles and practices assume a linear dose-response relationship-the linear no-threshold (LNT) model-that theoretically estimates cancer risks occurring following low doses of carcinogens by linearly extrapolating downward from experimentally determined risks at high doses. The two-year rodent bioassays serve as experimental vehicles to determine the high-dose cancer risks in animals and then to predict, by extrapolation, the number of carcinogen-induced tumors (tumor incidence) that will arise during the lifespans of humans who are exposed to environmental carcinogens at doses typically orders of magnitude below those applied in the rodent assays. An integrated toxicological analysis is conducted herein to reconsider an alternative and once-promising approach, tumor latency, for estimating carcinogen-induced cancer risks at low doses. Read More

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Short sleep duration and physical and psychological health outcomes among adult survivors of childhood cancer.

Pediatr Blood Cancer 2021 Apr 6:e28988. Epub 2021 Apr 6.

Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee.

Background: To examine associations between phenotypes of short sleep duration and clinically assessed health conditions in long-term survivors of childhood cancer.

Methods: Survivors recruited from the St. Jude Lifetime Cohort (n = 911; 52% female; mean age 34 years; 26 years postdiagnosis) completed behavioral health surveys and underwent comprehensive physical examinations. Read More

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Self-Reported Shorter Than Desired Ejaculation Latency and Related Distress-Prevalence and Clinical Correlates: Results From the European Male Ageing Study.

J Sex Med 2021 Apr 2. Epub 2021 Apr 2.

Endocrinology Unit, Mario Serio" Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy. Electronic address:

Background: Few data have looked at the occurrence and clinical correlates of self-reported shorter than desired ejaculation latency (rapid ejaculation, RE) and its related distress in the general population.

Aim: To determine the prevalence and clinical correlates of self-reported RE and RE- related distress in middle age and older European men.

Methods: Subjects were recruited from population samples of men aged 40-79 years across 8 European centers. Read More

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The effect of group cognitive behavioural therapy for insomnia in postmenopausal women.

J Sleep Res 2021 Apr 5:e13345. Epub 2021 Apr 5.

Faculty of Public Health, Department of Statistics and Epidemiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

The menopausal period is associated with several complications in women. One of these complications is sleep disorders including insomnia disorder that can affect all aspects of personal life. The present study aimed to evaluate the effectiveness of cognitive behavioural therapy for insomnia (CBT-I) on insomnia severity and sleep quality among postmenopausal women. Read More

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HARP: Hierarchical Attention Oriented Region-Based Processing for High-Performance Computation in Vision Sensor.

Sensors (Basel) 2021 Mar 4;21(5). Epub 2021 Mar 4.

Electrical and Computer Engineering Department, University of Florida, Gainesville, FL 32603, USA.

Cameras are widely adopted for high image quality with the rapid advancement of complementary metal-oxide-semiconductor (CMOS) image sensors while offloading vision applications' computation to the cloud. It raises concern for time-critical applications such as autonomous driving, surveillance, and defense systems since moving pixels from the sensor's focal plane are expensive. This paper presents a hardware architecture for smart cameras that understands the salient regions from an image frame and then performs high-level inference computation for sensor-level information creation instead of transporting raw pixels. Read More

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The Evolving Landscape of the Molecular Epidemiology of Malignant Pleural Mesothelioma.

J Clin Med 2021 Mar 3;10(5). Epub 2021 Mar 3.

Department of Medical Sciences and Infective Diseases, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation, University of Pavia Medical School, 27100 Pavia, Italy.

Malignant pleural mesothelioma (MPM) is a rare and aggressive malignancy that most commonly affects the pleural lining of the lungs. It has a strong association with exposure to biopersistent fibers, mainly asbestos (80% of cases) and-in specific geographic regions-erionite, zeolites, ophiolites, and fluoro-edenite. Individuals with a chronic exposure to asbestos generally have a long latency with no or few symptoms. Read More

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Towards an Efficient CNN Inference Architecture Enabling In-Sensor Processing.

Sensors (Basel) 2021 Mar 10;21(6). Epub 2021 Mar 10.

Electrical and Computer Engineering Department, University of Florida, Gainesville, FL 32603, USA.

The astounding development of optical sensing imaging technology, coupled with the impressive improvements in machine learning algorithms, has increased our ability to understand and extract information from scenic events. In most cases, Convolution neural networks (CNNs) are largely adopted to infer knowledge due to their surprising success in automation, surveillance, and many other application domains. However, the convolution operations' overwhelming computation demand has somewhat limited their use in remote sensing edge devices. Read More

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Sleep and Awakening Quality during COVID-19 Confinement: Complexity and Relevance for Health and Behavior.

Int J Environ Res Public Health 2021 03 28;18(7). Epub 2021 Mar 28.

Instituto de Saúde Ambiental (ISAMB), Faculdade de Medicina, Universidade de Lisboa, 1649-026 Lisbon, Portugal.

Objective: The aim of this study was to evaluate sleep and awakening quality (SQ and AQ) during COVID-19 in a large and diversified population in order to identify significant associations and risks in terms of demography, health and health-related behaviors, sleep variables, mental health, and attitudes.

Methods/results: Online surveys were used for data collection, received from 5479 individuals from the general population, sleep disorder patients, and COVID-involved (medical doctors (MDs) and nurses) and COVID-affected professionals (teachers, psychologists, and dentists). SQ and AQ were worse in adults, females, and high-education subjects. Read More

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Risk of Second Primary Malignancies among Patients with Early Gastric Cancer Exposed to Recurrent Computed Tomography Scans.

Cancers (Basel) 2021 Mar 7;13(5). Epub 2021 Mar 7.

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.

Although computed tomography (CT) scans are very useful for identification or surveillance of malignancy, they are also associated with the risk of cancer caused by ionizing radiation. We investigated the risk of second primary malignancies (SPMs) after frequent abdominopelvic CT scans in a cohort of Korean patients with early gastric cancer (EGC). We performed a cohort study of 11,072 patients who underwent resection for EGC at Samsung Medical Center and validated the results using data from 7908 patients in a Korean National Health Insurance Service cohort. Read More

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Sleep quality and insomnia during the COVID-19 lockdown among the Saudi public: A cross-sectional study.

Saudi Med J 2021 Apr;42(4):384-390

From the Department of Pediatrics (Alharbi), Pediatric Sleep Disorders Center, Prince Sultan Military City, Ministry of Defense; from the Department of Neurosciences (Alshahrani), King Abdullah bin Abdulaziz University Hospital, Princess Nourah bint Abdulrahman University; from the Department of Pediatrics (Alsaadi), from the National Plan for Science and Technology (BaHammam), College of Medicine & King Khalid University Hospital; from the University Sleep Disorders Center (BaHammam), Department of Medicine, College of Medicine, King Saud University; from the Department of Medicine (AL-Jahdali), Sleep Disorder Center, King Saud Bin Abdulaziz for Health Sciences, Riyadh; and from the Sleep Medicine and Research Center (Wali), King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia.

Objectives: To measure the Saudi population's sleep quality during the lockdown of COVID-19.

Methods: An internet-based questionnaire that was performed during the lockdown of the COVID-19 pandemic among the Saudi population over 2 weeks from April 1 to April 15, 2020. We used the instant messaging application WhatsApp and Twitter to reach the targeted population. Read More

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