89,430 results match your criteria latency

To start or stop an action depends on which movement we perform: An appraisal of the horse-race model.

Acta Psychol (Amst) 2021 May 12;217:103332. Epub 2021 May 12.

Centre de Recherche Cerveau et Cognition, Université Toulouse 3 Paul Sabatier, France.

In order to ponder how adaptive behavior and its underlying executive processes are, a central criterion in psychology is the extent to which experimental findings generalize across response types. The latency of two major acts of control, action initiation and inhibition, was evaluated using a stop-signal paradigm with two response types, involving either a finger key-press or a wrist pen-swipe response. In both conditions, 40 participants were instructed to respond quickly to a GO stimulus but to cancel their responses when a STOP signal was presented, which occurred randomly in 25% of the trials. Read More

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Using the perfusion index to predict changes in the depth of anesthesia in children compared with the A-line Autoregression Index: an observational study.

Braz J Anesthesiol 2021 May 12. Epub 2021 May 12.

Assiut University, Faculty of Medicine, Anesthesia and Intensive Care Department, Assiut, Egypt.

Background: We investigated the performance of the Perfusion Index (PI) derived from pulse oximetry waveform as a tool for assessment of anesthetic depth in comparison with A-line Autoregression Index (AAI) derived from analysis of Middle-Latency Auditory Evoked Potentials (MLAEP) waveform integrated by aepEXplus monitor in children receiving sevoflurane anesthesia for tonsillectomy.

Methods: Forty-one patients (4-12 years old) were included in this study. The PI and AAI were recorded simultaneously every minute during different stages of anesthesia delivery. Read More

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Investigation of therapeutic effect of Curcumin α and β Glucoside anomers against Alzheimer's disease by the nose to brain drug delivery.

Brain Res 2021 May 12:147517. Epub 2021 May 12.

Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran; Department of Pharmacology and toxicology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.

Alzheimer's disease (AD) is one of the greatest geriatric medicinal challenges of our century and is the main disease leading to dementia. Despite extensive scientific research advances, available disease-modifying treatment strategies remained limited; thus, increasing demand for new drugs. In recent years, medicinal plants attracted attention due to their potential role in dementia. Read More

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REM sleep latency as an independent risk for cardiovascular events in hemodialysis patients.

Physiol Rep 2021 May;9(9):e14837

Department of Nephrology, Shirasagi Hospital, Osaka, Japan.

Background: Clinical significance of objectively measured poor sleep quality (SQ) as a risk for cardiovascular disease (CVD) events is not well known in hemodialysis (HD) patients, independently of sleep-related breathing disorders (SRBDs) and sleep-related metabolic abnormality.

Methods: The present study investigated baseline levels of objective sleep architecture together with obstructive sleep apnea (OSA) and central sleep apnea (CSA) using polysomnography in 88 HD study participants (M/F, 56/32; age 68.4 ± 9. Read More

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Association of Depressive Symptoms with Sleep Disturbance: A Co-twin Control Study.

Ann Behav Med 2021 May 15. Epub 2021 May 15.

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

Background: Few studies have comprehensively evaluated the association of depression with sleep disturbance using a controlled twin study design.

Purpose: To cross-sectionally evaluate the association of depression with both objective and subjective sleep disturbance.

Methods: We studied 246 members of the Vietnam Era Twin Registry. Read More

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Circadian typology and implications for adolescent sleep health. Results from a large, cross-sectional, school-based study.

Sleep Med 2021 Apr 22;83:63-70. Epub 2021 Apr 22.

Norwegian Competence Center for Sleep Disorders, Haukeland University Hospital, Norway; Centre for Sleep Medicine, Haukeland University Hospital, Norway; Department of Global Public Health and Primary Care, University of Bergen, Norway.

Study Objectives: To investigate circadian typology in a large, representative sample of Norwegian adolescents, and its implications for sleep health.

Methods: The sample included 3920 1 year high school students aged 16-17 years. Respondents completed a web-based survey, including the short version of the Horne-Ostberg Morningness-Eveningness Questionnaire (rMEQ), the Munich Chronotype Questionnaire (MCTQ) and items on sleep-related behaviors (eg electronic media usage in bed, consumption of caffeinated beverages), sleep beliefs and daytime sleepiness. Read More

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Bedsharing in Early Childhood: Frequency, Partner Characteristics, and Relations to Sleep.

J Genet Psychol 2021 May 14:1-20. Epub 2021 May 14.

Department of Psychological & Brain Sciences, University of Massachusetts, Amherst, Massachusetts, USA.

Bedsharing (sharing a bed with others during sleep) in early childhood (3-5 years old) is common across Western and non-Western societies alike. Though prior work indicates that bedsharing may relate to impairments in child sleep quantity or quality, the majority of studies conducted in young children are limited to parent-child bedsharing and rely almost exclusively on caregiver reports to measure child sleep. Here, the authors endeavored to gain further insights into the diversity of bedsharing practices among children in the United States, including how different bedsharing partners (caregivers, siblings) might impact actigraphy-derived measures of children's sleep. Read More

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Efficacy and Safety of Penile Girth Enhancement Using Hyaluronic Acid Filler and the Clinical Impact on Ejaculation: A Multi-Center, Patient/Evaluator-Blinded, Randomized Active-Controlled Trial.

World J Mens Health 2021 May 7. Epub 2021 May 7.

Department of Urology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.

Purpose: We aimed to evaluate the efficacy and safety of penile girth enhancement (PGE) using hyaluronic acid (HA) filler with different physical properties from previous studies. Additionally, we evaluated the clinical impact on ejaculation after PGE.

Materials And Methods: This was a prospective, patient/evaluator-blinded, randomized, active-controlled, multicenter trial. Read More

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Dexterous manual movement facilitates information processing in the primary somatosensory cortex: A magnetoencephalographic study.

Eur J Neurosci 2021 May 13. Epub 2021 May 13.

Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan.

The interaction between the somatosensory and motor systems is important for control of movement in humans. Cortical activity related to somatosensory response and sensory perception is modulated by the influence of movement executing mechanisms. This phenomenon has been observed as inhibition in the short-latency components of somatosensory evoked potentials and magnetic fields (SEPs/SEFs). Read More

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Effect of Leaf Extract on Scopolamine-Induced Memory Deficits in Zebrafish: The Model of Alzheimer's Disease.

Adv Pharmacol Pharm Sci 2021 24;2021:6666726. Epub 2021 Apr 24.

Department of Pharmaceutical Care, School of Pharmaceutical Sciences, University of Phayao, Phayao 56000, Thailand.

(SA) is well known as a folk medicinal plant in Asian countries. The effect of SA extract on preventing memory impairment in zebrafish induced by scopolamine was investigated. Male zebrafish, , were divided into 6 groups including the control, scopolamine 200 M (SCO), scopolamine plus rivastigmine 1. Read More

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Proprieties of adhesive surface arrays to thyroid cartilage for recurrent laryngeal nerve monitoring.

Ann Transl Med 2021 Apr;9(8):690

Division of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, Changchun, China.

Background: To investigate the optimal placement and size of adhesive thyroid cartilage electrodes (ATCEs) placed on the thyroid cartilage in porcine models for evaluating recurrent laryngeal nerve function compared with the other 3 recording electrode types.

Methods: Four Meishan piglets were used for this study. The electromyogram (EMG) signal stability was detected by intraoperative nerve monitoring (IONM). Read More

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Assessment of HCMV-encoded microRNAs in plasma as potential biomarkers in pregnant women with adverse pregnancy outcomes.

Ann Transl Med 2021 Apr;9(8):638

State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, Nanjing, China.

Background: Human cytomegalovirus (HCMV) is the most frequent cause of congenital infections and can lead to adverse pregnancy outcomes (APOs). HCMV encodes multiple microRNAs (miRNAs) that have been reported to be partially related to host immune responses, cell cycle regulation, viral replication, and viral latency, and can be detected in human plasma. However, the relevance for HCMV-encoded miRNAs in maternal plasma as an indicator for APOs has never been evaluated. Read More

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Off-training physical activity and training responses as determinants of sleep quality in young soccer players.

Sci Rep 2021 May 13;11(1):10219. Epub 2021 May 13.

Research Center in Sports Sciences, Health Sciences and Human Development, CIDESD, CreativeLab Research Community, Vila Real, Portugal.

This study aimed to quantify and assess the relationship of young soccer players' off-training physical activity (PA) and training responses on sleep quality. Eleven adolescent soccer players (13 ± 0.5 years old) were monitored during weekdays for four consecutive weeks, throughout soccer practice days. Read More

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Inhibition of CCL7 derived from Mo-MDSCs prevents metastatic progression from latency in colorectal cancer.

Cell Death Dis 2021 May 13;12(5):484. Epub 2021 May 13.

Department of Pathology, Nanfang Hospital and Basic Medical College, Southern Medical University, Guangzhou, 510515,, Guangdong Province, People's Republic of China.

In colorectal cancer (CRC), overt metastases often appear after years of latency. But the signals that cause micro-metastatic cells to remain indolent, thereby enabling them to survive for extended periods of time, are unclear. Immunofluorescence and co-immunoprecipitation assays were used to explore the co-localization of CCL7 and CCR2. Read More

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Sleep Disorders in Parkinson Disease.

Sleep Med Clin 2021 Jun 15;16(2):323-334. Epub 2021 Apr 15.

Department of Neurology, Medical University of Innsbruck, Anichstr. 35, Innsbruck 6020, Austria. Electronic address:

Sleep disorders in Parkinson disease have attracted the attention of clinicians and researchers for decades. Recently, major advances in their clinical characterization, polysomnographic description, pathophysiologic understanding, and treatment took place. Parkinson disease encompasses the whole spectrum of sleep medicine: every category of sleep disorder can be observed in these patients. Read More

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The clinical effects of sleep restriction therapy for insomnia: A meta-analysis of randomised controlled trials.

Sleep Med Rev 2021 Apr 21;58:101493. Epub 2021 Apr 21.

Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, UK. Electronic address:

Sleep restriction therapy (SRT) is an established treatment for insomnia that has been used in clinical practise for over 30 y. It is commonly delivered as part of multicomponent cognitive-behavioural therapy (CBT-I) but has also been linked to beneficial effects as a standalone intervention. In order to quantify the efficacy of SRT we performed a comprehensive meta-analysis of randomised controlled trials (RCTs) comparing SRT to minimally active or non-active control groups. Read More

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Are extracapsular and intracapsular hip-fracture patients two distinct rehabilitation subpopulations?

Disabil Rehabil 2021 May 13:1-6. Epub 2021 May 13.

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Purpose: To assess whether intracapsular and extracapsular hip fracture patients in a post-acute rehabilitation setting differ in their background characteristics and whether fracture type affects rehabilitation outcome.

Methods: A retrospective cohort study.

Outcome Measures: Functional Independence Measure (FIM), motor FIM (mFIM), mFIM effectiveness, length of stay (LOS), and discharge destination. Read More

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EEG alterations during wake and sleep in mild cognitive impairment and Alzheimer's disease.

iScience 2021 Apr 1;24(4):102386. Epub 2021 Apr 1.

Department of Psychology, University of Rome "Sapienza", Via dei Marsi, 78, Rome 00185, Italy.

Patients with Alzheimer's disease (AD) undergo a slowing of waking electroencephalographic (EEG) rhythms since prodromal stages, which could be ascribed to poor sleep quality. We examined the relationship between wake and sleep alterations by assessing EEG activity during sleep and (pre-sleep/post-sleep) wakefulness in AD, mild cognitive impairment (MCI) and healthy controls. AD and MCI show high sleep latency and less slow-wave sleep. Read More

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Effects of extract on learning and memory ability, brain tissue morphology, and immune function of aging mice.

Open Life Sci 2021 23;16(1):399-407. Epub 2021 Apr 23.

Department of Pharmacy, Luohe Medical College, Luohe 462000, China.

In this study, we aimed to observe the effects of (LC) extract on learning and memory ability, brain tissue morphology, and immune function of aging mice. Kunming mice were selected and randomly divided into a control group, a positive control group, an aging group, and three dose groups. Three dose groups were administered 187. Read More

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Saccade Landing Point Prediction Based on Fine-Grained Learning Method.

IEEE Access 2021 1;9:52474-52484. Epub 2021 Apr 1.

Schepens Eye Research Institute, Massachusetts Eye and Ear, Boston, MA 02114, USA.

The landing point of a saccade defines the new fixation region, the new region of interest. We asked whether it was possible to predict the saccade landing point early in this very fast eye movement. This work proposes a new algorithm based on LSTM networks and a fine-grained loss function for saccade landing point prediction in real-world scenarios. Read More

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Acute Transverse Myelitis (ATM):Clinical Review of 43 Patients With COVID-19-Associated ATM and 3 Post-Vaccination ATM Serious Adverse Events With the ChAdOx1 nCoV-19 Vaccine (AZD1222).

Front Immunol 2021 26;12:653786. Epub 2021 Apr 26.

Neurosurgery Service, Complejo Hospitalario Metropolitano, CSS, Panama City, Panama.

Introduction: Although acute transverse myelitis (ATM) is a rare neurological condition (1.34-4.6 cases per million/year) COVID-19-associated ATM cases have occurred during the pandemic. Read More

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Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats.

Sci Rep 2021 May 12;11(1):10061. Epub 2021 May 12.

Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing, 100850, China.

Previous studies have shown that single-frequency microwave radiation can lead to cognitive decline in rats. However, few studies have focused on the combined effects of irradiation with different frequencies of microwaves. Our research aimed to investigate the effects of 1. Read More

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Selective BCL-X Antagonists Eliminate Infected Cells from a Primary Cell Model of HIV Latency but not from Reservoirs.

J Virol 2021 May 12. Epub 2021 May 12.

Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York NY, USA.

HIV persists, despite immune responses and antiretroviral therapy, in viral reservoirs that seed rebound viremia if therapy is interrupted. Previously, we showed that the BCL-2 protein contributes to HIV persistence by conferring a survival advantage to reservoir-harboring cells. Here, we demonstrate that many of the BCL-2 family members are overexpressed in HIV-infected CD4 T-cells, indicating increased tension between pro-apoptotic and pro-survival family members - and suggesting that inhibition of pro-survival members may disproportionately affect the survival of HIV-infected cells. Read More

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Technical assessment of the NDI Polaris Vega optical tracking system.

Radiat Oncol 2021 May 12;16(1):87. Epub 2021 May 12.

Center for Proton Therapy, Paul Scherrer Institute, Forschungsstrasse 111, 5232, Villigen, Switzerland.

The Polaris product line from Northern Digital Inc. is well known for accurate optical tracking measurements in research and medical environments. The Spectra position sensor, to date often found in image guided radiotherapy suites, has however reached its end-of-life, being replaced by the new Vega model. Read More

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Risk and outcome of subsequent malignancies after radioactive iodine treatment in differentiated thyroid cancer patients.

BMC Cancer 2021 May 13;21(1):543. Epub 2021 May 13.

Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: We identified differentiated thyroid cancer (DTC) survivors from SEER registries and performed Poisson regression to calculate the relative risks (RRs) of subsequent malignancies (SMs) by different sites associated with radioactive iodine (RAI) treatment, and the attributable risk proportion of RAI for developing different SMs.

Results: We identified 4628 of 104,026 DTC patients developing a SM after two years of their DTC diagnosis, with a medium follow-up time of 113 months. The adjusted RRs of developing SM associated with RAI varied from 0. Read More

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Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks.

PLoS One 2021 12;16(5):e0251363. Epub 2021 May 12.

Department of Speech, Language, and Hearing Sciences, University of Texas, Austin, Texas, United States of America.

Auditory brainstem responses (ABRs) and auditory middle-latency responses (AMLRs) to a click stimulus were measured in about 100 subjects. Of interest were the sex differences in those auditory evoked potentials (AEPs), the correlations between the various AEP measures, and the correlations between the AEP measures and measures of otoacoustic emissions (OAEs) and behavioral performance also measured on the same subjects. Also of interest was how the menstrual cycle affected the various AEP measures. Read More

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Neuroprotective Effect of Ultrasound Neuromodulation on Kainic Acid-Induced Epilepsy in mice.

IEEE Trans Ultrason Ferroelectr Freq Control 2021 May 12;PP. Epub 2021 May 12.

Preliminary evidence suggest that low intensity pulsed ultrasound (LIPUS) has neuroprotective effects on ischemic stroke, d epression and other conditions leading to neuronal cell death (e.g., Pa rkinson's disease). Read More

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Stereotactic Radiosurgery for Differentiated Thyroid Cancer Brain Metastases: An International, Multicenter Study.

Thyroid 2021 May 11. Epub 2021 May 11.

Department of Neurosurgery, University of Virginia, Charlottesville, Virginia, USA.

Brain metastases (BM) from differentiated thyroid cancer are rare. Stereotactic radiosurgery (SRS) is commonly used for the treatment of BMs; however, the experience with SRS for thyroid cancer BMs remains limited. The goal of this international, multi-centered study was to evaluate the efficacy and safety of SRS for thyroid cancer BMs. Read More

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Evaluation of the effect of shift working and sleep quality on semen parameters in men attending infertility clinic.

Andrologia 2021 May 12:e14116. Epub 2021 May 12.

Department of Urology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.

We aimed to evaluate the effect of shift work on semen parameters together with the effect of sleep quality in men attending infertility clinic. The participants were divided into two groups as follows: 104 shift worker men (Group 1) and 116 nonshift worker men (Group 2). Groups were compared in terms of semen parameters, Depression Anxiety Stress Scale-21 (DASS-21), and Pittsburg Sleep Quality Index (PSQI) scores. Read More

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Dietary n-3 PUFA Deficiency Increases Vulnerability to Scopolamine-Induced Cognitive Impairment in Male C57BL/6 Mice.

J Nutr 2021 May 12. Epub 2021 May 12.

College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong, China.

Background: DHA (22:6n-3), a long-chain n-3 PUFA, is essential for normal brain development and function. Our previous study demonstrated that DHA significantly improves scopolamine-induced dementia. However, there are no reports on the relation between n-3 PUFA deficiency and scopolamine-induced cognitive impairment. Read More

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