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Development of endometrial cancer after long-term usage of the levonorgestrel-releasing intrauterine system.

BMJ Case Rep 2021 May 13;14(5). Epub 2021 May 13.

Pathology, Queen Elizabeth Hospital, London, London, UK.

A 52-year-old long-term user of the levonorgestrel-releasing intrauterine system (LNG-IUS) presented with vaginal bleeding. Endometrial biopsy was performed and revealed endometrioid adenocarcinoma. The patient had a laparoscopic hysterectomy and bilateral salpingo-oophorectomy. Read More

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Laparoendoscopic single-site simultaneous bilateral nephrectomy: first reported case series.

Cent European J Urol 2021 15;74(1):44-47. Epub 2021 Jan 15.

Clinic Institute of Nephrology and Urology (ICNU), Universidad de Barcelona, Barcelona, Spain.

Bilateral renal tumors in patients on dialysis are usually managed with bilateral nephrectomy. With traditional laparoscopy, this procedure requires the insertion of multiple trocars. Laparoendoscopic single-site surgery (LESS) uses a single umbilical incision to insert multiple instruments and is also employed for extraction of specimens. Read More

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January 2021

Effects of Transcutaneous Electrical Acupoint Stimulation on Postoperative Cognitive Decline in Elderly Patients: A Pilot Study.

Clin Interv Aging 2021 3;16:757-765. Epub 2021 May 3.

Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, People's Republic of China.

Background: Postoperative cognitive decline (POCD) in the old ages seriously delays the rapid recovery. Here, we aimed to investigate the effects of transcutaneous electrical acupoint stimulation (TEAS) against POCD in elderly patients undergoing laparoscopic radical colon cancer surgery, as well as the potential mechanism.

Methods: A prospective, single-center, parallel-group, randomized trial was designed. Read More

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Double Appendix: Implications for the Emergency Department.

J Emerg Med 2021 May 7. Epub 2021 May 7.

University of Maryland Baltimore Washington Medical Center, Glen Burnie, Maryland.

Background: A double appendix, also known as vermiform appendix duplex, is a rare anomaly in humans, with a reported incidence of 1 in 25,000. The rarity of vermiform appendix duplication makes it a noteworthy medical occurrence. Approximately 100 reported cases have been documented since the first observed case in 1892. Read More

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A novel nonsense mutation in ARMC5 causes primary bilateral macronodular adrenocortical hyperplasia.

BMC Med Genomics 2021 May 10;14(1):126. Epub 2021 May 10.

Branch of National Clinical Research Center for Metabolic Disease, Hubei, Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Background: Primary bilateral macronodular adrenocortical hyperplasia (PBMAH) is a rare form of adrenal Cushing's syndrome. The slowly progressing expansion of bilateral adrenal tissues usually persists for dozens of years, leading to delayed onset with severe conditions due to chronic mild hypercortisolism. About 20-50% cases were found to be caused by inactivating mutation of armadillo repeat-containing protein 5 (ARMC5) gene. Read More

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Live birth by cesarean section after rupture of uterine cornua in simultaneous corneal and intrauterine pregnancies.

J Obstet Gynaecol Res 2021 May 9. Epub 2021 May 9.

Department of Obstetrics and Gynecology, The Japanese Red Cross Maebashi Hospital, Maebashi, Japan.

A patient became pregnant by in vitro fertilization and embryo transfer (IVF-ET). She had a history of laparoscopic bilateral salpingectomy and enucleation of a left ovarian tumor due to bilateral hydrosalpinx and left endometriotic cyst in primary infertility. She noticed abdominal pain and visited the nearby general hospital by ambulance (gestational age 6 weeks and 1 day). Read More

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[Intestinal and appendicular ureteral substitution].

Urologiia 2021 May(2):14-20

Department of Urology of FGBOU VO North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia.

Aim: To present the technical features and results of intestinal and appendicular ureteral replacement.

Material And Methods: From 1998 to 2020, a total of 196 patients aged 18 to 77 years (mean age 49.5 +/- 1. Read More

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Comparison of Open Repair and Laparoscopic Percutaneous Internal Ring Suturing Method in Repairing Inguinal Hernia in Children.

Cureus 2021 Apr 2;13(4):e14262. Epub 2021 Apr 2.

Pediatric Surgery, Dr. Sami Ulus Health Research and Training Center, Ankara, TUR.

Introduction An inguinal indirect hernia is one of the most frequent surgical conditions in children. In this study the experience with laparoscopic percutaneous internal ring suturing (PIRS) and open inguinal hernia surgery and their relations evaluated. Methods All children over 90 days of age and without having prior inguinal region surgery with a diagnosis of indirect inguinal hernia underwent surgical repair with open or laparoscopic PIRS technique. Read More

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Genitalia Preserving Robotic Radical Cystectomy with Intracorporeal Studer Pouch Formation in the Female: Experience in 5 Cases.

Robot Surg 2021 28;8:1-7. Epub 2021 Apr 28.

Koç University, School of Medicine, Department of Urology, Istanbul, Turkey.

We present operative, postoperative, oncologic and functional outcomes of genital tract sparing robot-assisted laparoscopic radical cystectomy, bilateral extended pelvic lymph node (LN) dissection and intracorporeal Studer pouch construction on five female patients with bladder cancer. One of the cases had concomitant nephroureterectomy performed due to a non-functioning kidney. Median patient age, mean operation time, median estimated blood loss and mean duration of hospital stay were 59 (39-78), 462 ± 25, 400 (50-970), 8. Read More

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Sentinel Lymph Node Biopsy Is Feasible in Cervical Cancer Laparoscopic Surgery: A Single-Center Retrospective Cohort Study.

J Oncol 2021 16;2021:5510623. Epub 2021 Apr 16.

Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, China.

Methods: A total of 100 cervical cancer patients undergoing laparoscopic surgery with SLN biopsy were included. Indocyanine green, carbon nanoparticles (CNPs), and a combination of both were used during surgeries. Detection rates, sensitivity, negative predictive value (NPV) of SLN biopsy, and related factors were analyzed. Read More

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Conservative treatment for hypervascularised placental polyp with secondary haemoperitoneum: a case report.

Acta Biomed 2021 Apr 30;92(S1):e2021157. Epub 2021 Apr 30.

Department of Medicine and Surgery, Unit of Surgical Sciences, Obstetrics and Gynecology University of Parma.

Objective: We describe the first case to our knowledge of Hypervascularised placental polyp (HPP) presenting with acute pelvic pain and hemoperitoneum.

Case Report: A 33 years-old woman with a history of medical abortion three months earlier came to our attention complaining acute pelvic pain and vaginal bleeding. Transvaginal (TV) and transabdominal (TA) ultrasound (US) demonstrated a highly vascular intrauterine lesion and intra-abdominal free fluid consistent with a diagnosis of haemoperitoneum. Read More

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Iatrogenic ureterovaginal fistula after laparoscopic hysterectomy: a case report.

Prz Menopauzalny 2021 Apr 11;20(1):48-51. Epub 2021 Mar 11.

Urology Department, Regional Specialized Hospital in Nowa Sól, Poland.

Introduction: The highest risk of intraoperative ureteral trauma is associated with hysterectomy, performed most frequently in postmenopausal women. The overall incidence of ureteral injuries varies in different studies between 0.5% and 10%. Read More

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Ultrasound-guided quadratus lumborum block for surgical treatment of endometriosis: case report.

Braz J Anesthesiol 2021 Feb 6. Epub 2021 Feb 6.

Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Departamento de Anestesiologia, Campinas, SP, Brazil. Electronic address:

Quadratus lumborum block (QLB) is a technique that is not widely applied for gynecological surgery. Endometriosis affects 10% of the female population and chronic pelvic pain is one of the most prevalent symptoms. Laparoscopic surgery for removal of endometriosis may present a long intra-operative duration and this technique might improve postoperative pain control. Read More

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February 2021

Bilateral versus unilateral erector spinae plane block for postoperative analgesia in laparoscopic cholecystectomy: a randomized controlled study.

Braz J Anesthesiol 2021 Apr 28. Epub 2021 Apr 28.

Kocaeli University, School of Medicine, Department of Anesthesiology and Reanimation, Kocaeli, Turkey.

Introduction: Laparoscopic cholecystectomy (LC) is the common surgical intervention for benign biliary diseases. Postoperative pain after LC remains as an important problem, with two components: somatic and visceral. Trocar entry incisions lead to somatic pain, while peritoneal distension with diaphragm irritation leads to visceral pain. Read More

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Outcome of bilateral equid laparoscopic ovariectomies.

Vet Surg 2021 May 1. Epub 2021 May 1.

Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA.

Objective: To assess outcomes and behavior changes associated with bilateral laparoscopic ovariectomies.

Study Design: Retrospective study.

Sample Population: Fifty-one equids. Read More

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Learning Curve for Laparoscopic Repair of Pediatric Inguinal Hernia Using Percutaneous Internal Ring Suturing.

Children (Basel) 2021 Apr 11;8(4). Epub 2021 Apr 11.

Department of Pediatric Surgery, University Hospital of Split, 21000 Split, Croatia.

Background: Percutaneous internal ring suturing (PIRS) is a simple and popular technique for the treatment of inguinal hernia in children. The aim of this study was to analyze the learning curves during implementation of PIRS in our department.

Methods: A total of 318 pediatric patients underwent hernia repair using the PIRS technique by three pediatric surgeons with different levels of experience in laparoscopic surgery. Read More

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Minimally invasive laparoscopic technique for lymph node dissection in penile cancer: the Pelvic and Inguinal Single-site Approach: PISA technique.

Urology 2021 Apr 26. Epub 2021 Apr 26.

Servicio de Urología. Hospital General Universitario Gregorio Marañón, Madrid, Spain. Electronic address:

Background: Lymph node dissection(LND) remains the gold standard in the staging and treatment of locally advanced penile cancer(PC).

Objective: To describe our initial experience with a new minimally invasive inguinal and pelvic single-access laparoscopic approach,for performing LND in PC, first described in Urology by our group in 2015: the Pelvic and Inguinal Single Access(PISA) technique (Figure 1).

Material: Between 2015-2018, 10 consecutive patients with different PC stages and indication of inguinal LND (cN0 and ≥pT1G3 or cN1/cN2) were operated by means of the PISA technique (Table 1). Read More

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Hysterosalpingography in the assessment of proximal tubal pathology: a review of congenital and acquired abnormalities.

Br J Radiol 2021 Apr 29:20201386. Epub 2021 Apr 29.

Department of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, Academic Center for Education, Culture, and Research (ACECR), Tehran, Iran.

Tubal and peritoneal disease are the main causes of infertility. Tubal pathology can be either congenital malformation or acquired, proximal or distal, unilateral or bilateral and transient or permanent. Several imaging methods such as laparoscopy, fluoroscopy, saline infusion sonography, and hysterosalpingography (HSG) have been used in the assessment of tubal and peritoneal pathology. Read More

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Assessment of surgeon and hospital volume for robotic-assisted and laparoscopic benign hysterectomy in Sweden.

Acta Obstet Gynecol Scand 2021 Apr 24. Epub 2021 Apr 24.

Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.

Introduction: The study aims to analyze differences between robotic-assisted total laparoscopic hysterectomy (RATLH) and total laparoscopic hysterectomy (TLH) in benign indications, emphasizing surgeon and hospital volume.

Material And Methods: All women in Sweden undergoing a total hysterectomy on benign indications with or without a bilateral salpingo-oophorectomy from 1 January 2015 to 31 December 2017 (n=12 386) were identified from three national Swedish registers. Operative time, blood loss, conversion rate, complications, readmission, reoperation, length of hospital stays and time to daily life activity were evaluated by uni- and multivariable regression models in RATLH and TLH. Read More

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Laparoscopic management of a primary posterior cul-de-sac abdominal ectopic pregnancy.

Fertil Steril 2021 Apr 20. Epub 2021 Apr 20.

Department of Obstetrics and Gynecology, New York Presbyterian Hospital-Weill Cornell Medicine, New York, New York. Electronic address:

Objective: To report a case of laparoscopic management of a primary posterior cul-de-sac abdominal ectopic pregnancy (AEP).

Design: Video article.

Setting: Academic medical center. Read More

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Maximizing sentinel node detection in endometrial cancer with dual cervical and transcervical fundal indocyanine green injection: 5-year single-center prospective study.

Eur J Obstet Gynecol Reprod Biol 2021 Apr 15;261:59-64. Epub 2021 Apr 15.

Hospital Universitario Donostia, San Sebastián, Spain.

Objective: The aim of this study was to describe our latest results using dual cervical and fundal indocyanine green injection for detection of sentinel lymph node (SLN) in endometrial cancer.

Methods: A prospective observational study was conducted between 26 June 2014 and 31 December 2019 with 278 patients that underwent laparoscopic surgery for endometrial cancer at our institution. In all cases, we performed SLN biopsy with dual cervical and fundal indocyanine green injection. Read More

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Is chronic endometritis associated with tubal infertility? A prospective cohort study.

J Minim Invasive Gynecol 2021 Apr 20. Epub 2021 Apr 20.

Parryscope and Positive Steps Fertility, Madison, Mississippi; Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, Mississippi.

Study Objective: Chronic endometritis (CE) which often presents asymptomatically, is associated with recurrent pregnancy loss, recurrent implantation failure after in-vitro-fertilization, and endometriosis. Data connecting CE with Fallopian tubal occlusion are limited. The aim was to assess a potential association of CE defined by the presence of CD138 positive plasma cells in endometrial tissue samples with Fallopian tube patency and other factors for infertility including endometriosis, adenomyosis and hydrosalpinges. Read More

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Sentinel lymph node detection in endometrial cancer with indocyanine green: laparoscopic versus robotic approach.

Facts Views Vis Obgyn 2021 Mar 31;13(1):15-25. Epub 2021 Mar 31.

Fondazione Policlinico Universitario A. Gemelli, IRCCS, UOC Ginecologia Oncologica, Dipartimento per la salute della Donna e del Bambino e della Salute Pubblica, Largo Agostino Gemelli 8, 00168, Rome, Italy.

Background: The aims of the present study were to assess bilateral sentinel lymph node (SLN) mapping with laparoscopic versus robotic approach, to assess variables affecting bilateral detection rates and to assess survival difference in patients with no/unilateral, compared to bilateral SLN detection.

Methods: This is a retrospective, single-centre, observational cohort study, including patients with endometrial cancer FIGO stage IA-IVB, treated with minimally invasive primary surgery and undergoing indocyanine green (ICG) injection to detect SLN, between January 2015 and December 2019.

Results: Of the 549 included patients, 286 (52. Read More

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Use of a Novel Fluorescent Catheter to Locate the Ureters During Total Laparoscopic Hysterectomy.

J Minim Invasive Gynecol 2021 Apr 19. Epub 2021 Apr 19.

Department of Obstetrics and Gynecology, Medical Park Shonan, Fujisawa, Kanagawa, Japan.

Ureteral injury can occur during total laparoscopic hysterectomy (TLH). This report documents our experience in using the Near-infrared Ray Catheter (NIRC™), a newly developed fluorescent ureteral catheter made of material that contains a fluorescent dye, to improve visualization of the ureters. We have used the device in three patients between 40 and 50 years of age (mean, 46. Read More

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Hysterectomy and bilateral adnexectomy using transvaginal natural orifice transluminal endoscopic surgery: The role of multichannel abdominal PORT and vaginal support ring.

J Obstet Gynaecol Res 2021 Apr 21. Epub 2021 Apr 21.

Department of Gynecology & Obstetrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Background: Although transvaginal natural orifice transluminal endoscopic surgery (NOTES) is gaining importance, knowledge on transvaginal NOTES procedures in gynecologic practice is limited.

Objective: We aimed at evaluating the feasibility and safety of performing hysterectomy and bilateral adnexectomy (or bilateral salpingectomy) via transvaginal NOTES using a self-developed multichannel abdominal port and vaginal support ring.

Study Design: A prospective, single-center, cohort pilot study was conducted from May to December 2017 in patients with benign uterine diseases or endometrial atypical hyperplasia or cervical intraepithelial neoplasia (n = 30) scheduled for laparoscopic hysterectomy. Read More

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Laparoscopic Nephrectomy for Massive Kidneys in Polycystic Kidney Disease.

JSLS 2021 Jan-Mar;25(1)

UO Chirurgia Trapianti Renali, Azienda Ospedaliero-Universitaria Senese, Viale Bracci 14, 53100 Siena, Italy.

Background And Objectives: Laparoscopic nephrectomy is now considered a feasible surgical approach, even for large kidneys. In the case of massive kidneys, laparoscopy can be problematic, so that some authors suggest an open approach. However, previous studies have shown that hand-assisted laparoscopic nephrectomy (HALN) may represent a useful compromise. Read More

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Tricky diagnosis and robot-laparoscopic surgical approach of disseminated peritoneal leiomyomatosis.

J Minim Invasive Gynecol 2021 Apr 17. Epub 2021 Apr 17.

Hospital Israelita Albert Einstein, São Paulo, Brazil.

Objective: To show the challenging diagnosis and safe robotic surgical approach of a rare case of disseminated peritoneal leiomyomatosis (DPL).

Design: A clinical case shown by a sequential demonstration of investigation, diagnosis and surgical approach, with narrated video footage.

Setting: DPL is a rare disease, with just over 150 cases reported in literature. Read More

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Impact of ultrasound on inguinal hernia repair rates in Australia: a population-based analysis.

ANZ J Surg 2021 Apr 18. Epub 2021 Apr 18.

The School of Medicine Sydney, The University of Notre Dame, Sydney, New South Wales, Australia.

Background: Inguinal hernias are a common pathology that often requires surgical management. The use of groin ultrasound (GU) to investigate inguinal hernias is a growing area of concern as an inefficient use of healthcare resources. Our aim was to assess changes in the rates of GU and the impact on surgical practice. Read More

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[Acute perforated appendicitis with pre-surgical diagnosis and bilateral inguinal hernia in preterm infants].

Rev Chil Pediatr 2020 Dec 21;91(6):936-940. Epub 2020 Oct 21.

Clínica Las Condes, Santiago, Chile.

Introduction: Acute neonatal appendicitis is a rare pathology, with few reports in the last 30 years. Since its clinical presentation and imaging studies are non-specific, most cases are diagnosed during a surgical pro cedure.

Objective: To describe a neonatal case of acute perforated appendicitis associated with later appearance of inguinal hernia, with pre-surgical diagnosis and treated through laparoscopy. Read More

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December 2020

Resolution of hyperthyroidism and thyroid antibodies following struma ovarii resection: an uncommon entity.

BMJ Case Rep 2021 Apr 15;14(4). Epub 2021 Apr 15.

Division of Endocrinology, Department of Medicine, The George Washington University, Washington, DC, USA

We report a case of 34-year-old clinically asymptomatic woman who had been followed for 6 years for hyperthyroidism with thyroid stimulating hormone <0.006 uIU/mL, free T4 1.98 ng/mL, free T3 5. Read More

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