1,329 results match your criteria lactobacillus brevis


Hypoglycemic and Hypolipidemic Activity of Fermented with YM 1301 in Diabetic C57BL/6 Mice.

J Med Food 2021 Jul;24(7):720-731

Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry, Ministry of Education, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Science, Shaanxi Normal University, Xi'an, Shaanxi, China.

(PS) has been used as herbal medicine to treat type 2 diabetes mellitus (T2DM). However, how lactic acid fermentation of PS influences glucose and lipid metabolism remains unclear. The current study was undertaken to evaluate the hypoglycemic and hypolipidemic effects of PS fermented with YM 1301 (YM 1301) in streptozotocin and high-fat diet-induced T2DM mice. Read More

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"More Guts Than Brains?"-The Role of Gut Microbiota in Idiopathic Intracranial Hypertension.

J Neuroophthalmol 2021 Jul 13. Epub 2021 Jul 13.

Department of Ophthalmology (EB, BT, AK), Hillel Yaffe Medical Center, Hadera, Israel; Institute of Gastroenterology and Hepatology (YK), Hillel Yaffe Medical Center, Hadera, Israel; Department of Cell Biology and Cancer Science (DK, SC, NG-K), Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Technion Integrated Cancer Center (TICC), Haifa, Israel; Sackler Faculty of Medicine (AK), Tel Aviv University, Tel Aviv, Israel; and Canadian Institute for Advanced Research (CIFAR) (NG-Z), Azrieli Global Scholar, MaRS Centre, Toronto, Canada.

Background: Idiopathic intracranial hypertension syndrome (IIH) is most common among obese women. Weight loss is an important factor in improving papilledema. Over the last decade, growing evidence has identified gut microbiota as a potential factor in the pathophysiology of obesity. Read More

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Study on relationship between bacterial diversity and quality of Huangjiu (Chinese Rice Wine) fermentation.

Food Sci Nutr 2021 Jul 4;9(7):3885-3892. Epub 2021 Jun 4.

Shaoxing Jianhu Brewing Co., Ltd Shaoxing China.

Huangjiu (Chinese rice wine) is brewed in an open environment, where bacteria play an important role during the fermentation process. In this study, bacterial community structure and composition changes in the fermented mash liquid of mechanized Huangjiu, well-fermented manual Huangjiu (wines of good qualities), and poorly fermented manual Huangjiu (wines of poor qualities: spoilage, high acidity, low alcohol content) in different fermentation stages from Guyuelongshan Shaoxing Huangjiu company were analyzed via metagenomic sequencing. And bacterial metabolic difference was analyzed via gene prediction of metabolic pathway enzymes. Read More

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The beneficial effects of FZU0713-fermented on lipid metabolism and intestinal microbiota in hyperlipidemic rats fed with a high-fat diet.

Food Funct 2021 Jul 7. Epub 2021 Jul 7.

College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, P. R. China.

This study aimed to investigate the beneficial effects of the oral administration of Lactobacillus brevis FZU0713-fermented Laminaria japonica (FLJ) on lipid metabolism and intestinal microbiota in hyperlipidemic rats fed with a high-fat diet (HFD). The results demonstrated that the oral administration of FLJ significantly inhibited obesity and improved the serum and hepatic biochemical parameters in HFD-fed rats. Histopathological results also indicated that FLJ intervention could significantly reduce the accumulation of lipid droplets in the liver induced by HFD feeding. Read More

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Massive Survey on Bacterial-Bacteriophages Biodiversity and Quality of Natural Whey Starter Cultures in Trentingrana Cheese Production.

Front Microbiol 2021 14;12:678012. Epub 2021 Jun 14.

Food Quality and Nutrition Department, Research and Innovation Centre, Fondazione Edmund Mach (FEM), San Michele all'Adige, Italy.

This study focused on the microbial and bacteriophages identification and characterization in cheese-production facilities that use natural whey starter (NWS) cultures for Trentingrana production. Bacterial and phage screening was carried out on cooked not acidified whey and NWS samples isolated from six dairy factories, for 4 consecutive days in four different months. By means of a combined approach, using plate counts, bacterial isolation, and metataxonomic analysis was found occurring as the dominant species in NWS cultures and as codominant in the cheese factories where the temperature of NWS production was mainly lower than 40°C, suggesting that the variability in the parameters of the NWS culture preparation could differently modulate the bacterial species in NWS cultures. Read More

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Priming with intranasal lactobacilli prevents Pseudomonas aeruginosa acute pneumonia in mice.

BMC Microbiol 2021 Jun 28;21(1):195. Epub 2021 Jun 28.

Univ Brest, Inserm, EFS, UMR 1078, GGB, Brest, France.

Background: Increasing resistance to antibiotics of Pseudomonas aeruginosa leads to therapeutic deadlock and alternative therapies are needed. We aimed to evaluate the effects of Lactobacillus clinical isolates in vivo, through intranasal administration on a murine model of Pseudomonas aeruginosa pneumonia.

Results: We screened in vitro 50 pulmonary clinical isolates of Lactobacillus for their ability to decrease the synthesis of two QS dependent-virulence factors (elastase and pyocyanin) produced by Pseudomonas aeruginosa strain PAO1. Read More

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Changes in physico-chemical characteristics and viable bacterial communities during fermentation of alfalfa silages inoculated with Lactobacillus plantarum.

World J Microbiol Biotechnol 2021 Jun 28;37(7):127. Epub 2021 Jun 28.

Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Zhaoaruda Road 306, Hohhot, 010018, People's Republic of China.

This study investigated the effect of inoculating Lactobacillus (L.) plantarum PS-8 in fermentation of alfalfa silages. We monitored the fermentation characteristics and bacterial population dynamics during the ensiling process. Read More

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Characterization of waste cell biomass derived glutamate decarboxylase for in vitro γ-aminobutyric acid production and value-addition.

Bioresour Technol 2021 Jun 17;337:125423. Epub 2021 Jun 17.

Department of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung City 81157, Taiwan.

Waste biomass of Lactobacillus brevis obtained from in vivo γ-aminobutyric acid (GABA) production was used for value-addition. This study aims to extract glutamate decarboxylase (GAD) and characterize it for in vitro GABA production. Extracted GAD showed an excellent activity for in vitro GABA production. Read More

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Optimization of gamma-aminobutyric acid production by PML1 in dairy sludge-based culture medium through response surface methodology.

Food Sci Nutr 2021 Jun 2;9(6):3317-3326. Epub 2021 May 2.

Department of Food Science and Technology Faculty of Agriculture Ferdowsi University of Mashhad Mashhad Iran.

Gamma-aminobutyric acid (GABA) is a pharmaceutical, bioactive amino acid that can produce by some species of Lactic Acid Bacteria (LAB). For the first time, we evaluated the production of GABA by PML1 in the medium that contain the contaminant food bio-product like dairy sludge and soybean meal. GABA production was analyzed by chromatography (TLC, HPLC) and the features of fermented extract which contains this amino acid were evaluated. Read More

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The Ability of Probiotic Lactobacillus Strains in Removal of Benzo[a]pyrene: a Response Surface Methodology Study.

Probiotics Antimicrob Proteins 2021 Jun 15. Epub 2021 Jun 15.

Department of Food Science and Technology, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

In this study, the ability of various lactic acid bacteria was assessed in removing benzo[a]pyrene (BaP) from contaminated phosphate buffer saline (PBS). Response surface methodology (RSM) was performed using Box-Behnken design to investigate the effect of four independent variables including pH (5-7), incubation time (1-24 h), cell density (10-10 cfu/mL), and initial BaP concentration (5-15 mg/kg) at three levels to evaluate in vitro removal of BaP as response. The results showed that all the tested strains were able to remove BaP from PBS and this reduction was entirely strain-specific. Read More

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Selection of lactic acid bacteria with promising probiotic aptitudes from fruit and ability to survive in different food matrices.

Braz J Microbiol 2021 Jun 14. Epub 2021 Jun 14.

Laboratório de Microbiologia de Alimentos, Departamento de Nutrição, Centro de Ciências da Saúde, Universidade Federal da Paraíba, Campus I, João Pessoa, Paraíba, Brazil.

Lactic acid bacteria (LAB) are among the most prevalent microorganisms forming the autochthonous microbiota of fruit. This study aimed to select LAB isolates with probiotic aptitudes from apple, banana, grape, and orange through evaluation of in vitro safety, technological, and functional-related properties. The ability of most promising selected isolates to survive in commercial apple and orange juice, meat stew, vegetable puree, and UHT milk during 28 days of refrigeration storage was evaluated. Read More

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Technological characterization of indigenous lactic acid bacteria from Moroccan camel milk for their potential use as starter or adjunct culture.

Folia Microbiol (Praha) 2021 Jun 10. Epub 2021 Jun 10.

RU Animal Production and Forage, Food Technology Laboratory, INRA, RCAR-Rabat, Institutes Rabat, 6570, 10101, Rabat, PB, Morocco.

This study aimed to isolate lactic acid bacteria (LABs) of technological interest from Moroccan camel milk and select starter or adjunct culture for dairy product manufacturing. The phenotypic and biochemical identification of 47 isolates revealed the existence of ten Lactococcus lactis, eleven Lactobacillus plantarum, three Lactobacillus brevis, two Lactobacillus paracasei, eleven Enterococcus spp., seven Lactococcus spp. Read More

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Genome analysis and optimization of γ-aminobutyric acid (GABA) production by lactic acid bacteria from plant materials.

J Gen Appl Microbiol 2021 Jun 5. Epub 2021 Jun 5.

Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University.

Gamma-aminobutyric acid (GABA) plays a key role as an inhibitory neurotransmitter in the mammalian sympathetic nervous system and has other health benefits. Molecular characterization, genome analysis, and optimization were investigated to improve GABA production of a selected strain of lactic acid bacteria. Eleven isolates from plant materials were screened for GABA productivity and were identified based on phenotypic and genotypic characteristics. Read More

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Effect of the Intake of a Traditional Mexican Beverage Fermented with Lactic Acid Bacteria on Academic Stress in Medical Students.

Nutrients 2021 May 5;13(5). Epub 2021 May 5.

Biological Science Department, Universidad Popular Autónoma del Estado de Puebla, Puebla 72410, Mexico.

Dysbiosis of the gut microbiota has been associated with different illnesses and emotional disorders such as stress. Traditional fermented foods that are rich in probiotics suggest modulation of dysbiosis, which protects against stress-induced disorders. The academic stress was evaluated in medical students using the SISCO Inventory of Academic Stress before and after ingestion of an aguamiel-based beverage fermented with , and (n = 27) and a control group (n = 18). Read More

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Selenium bio-enrichment of Mediterranean fruit juices through lactic acid fermentation.

Int J Food Microbiol 2021 May 24:109248. Epub 2021 May 24.

Department of Agricultural, Food and Forest Science, Università degli Studi di Palermo, Viale delle Scienze 4, 90128 Palermo, Italy. Electronic address:

This work was carried out to elaborate selenium (Se) bio-enriched fermented Mediterranean fruit juices. To this purpose, pomegranate and table red grape juices were added with sodium selenite (NaSeO) and fermented by Levilactobacillus brevis CRL 2051 and Fructobacillus tropaeoli CRL 2034 individually or combined. To better evaluate the effect of selenite addition and starter strain inoculums on the total bacterial community of the fruit juices, fermentation trials were performed with raw and pasteurized fruit juices. Read More

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Fermented date residue extract mix containing gamma-aminobutyric acid augments the immune function of mouse splenocytes.

Biosci Biotechnol Biochem 2021 Jun;85(7):1753-1758

Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, Japan.

An extract of date (fruit of a palm tree) residue plus food-grade glutamate, acetic acid, and yeast extract (date residue extract mix, DREM) has been successfully fermented with using Lactobacillus brevis JCM 1059T to produce gamma-aminobutyric acid (GABA). Here, mouse splenocytes were found to be viable when supplemented with DREM and fermented DREM containing GABA (fDREM). The addition of DREM and fDREM resulted in the secretion of tumor necrosis factor (TNF)-α from the splenocytes, fDREM being more effective than DREM. Read More

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Inhibitory effects of Lactobacillus brevis KU15153 against Streptococcus mutans KCTC 5316 causing dental caries.

Microb Pathog 2021 Aug 20;157:104938. Epub 2021 May 20.

Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, South Korea. Electronic address:

This study determined the inhibitory effect of Lactobacillus brevis KU15153 against cariogenic Streptococcus mutans KCTC 5316. Antimicrobial activity, auto-aggregation, cell surface hydrophobicity, exopolysaccharides (EPS) production, biofilm formation, and morphological changes were assessed in the presence of L. brevis KU15153. Read More

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Screening of Probiotic Lactic Acid Bacteria Isolated from Fermented Pak-Sian for Use as a Starter Culture.

Curr Microbiol 2021 Jul 21;78(7):2695-2707. Epub 2021 May 21.

Department of Food Technology and Nutrition, Faculty of Technology, Mahasarakham University, Khamriang Sub-District, Kantarawichai District, 44150, Maha Sarakham, Thailand.

The objective of this research was to evaluate the probiotic properties of lactic acid bacteria (LAB) isolated from fermented Pak-Sian, a traditional Thai food in the northeastern region of Thailand (Kalasin, Sakon Nakhon, Maha Sarakham, and Khon Kaen Provinces). A total of 61 LAB isolates isolated from selective MRS agar were screened by SDS-PAGE and identified by 16S rDNA analysis. Seventeen bacterial strains were found consisting of Pediococcus pentosaceus (6 strains) Lactiplantibacillus plantarum (5 strains), Levilactobacillus brevis (1 strain), Lactobacillus fermentum (3 strains), and Weissella cibaria (2 strains). Read More

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Screening for probiotic characters in lactobacilli isolated from chickens revealed the intra-species diversity of .

Anim Nutr 2021 Mar 28;7(1):119-126. Epub 2020 Dec 28.

Department of Microbiology, Pasteur Institute of Iran, Tehran, Iran.

Considering the importance of the poultry industry and the increasing interest in alternative growth promoters, probiotics are considered as a potential candidate for use in the poultry industry. In this study, species were isolated from 21 rectal swabs of 11 healthy 6-day-old and 10 healthy 21-day-old chickens and their fecal and feed samples. The isolates were characterized and their probiotic characteristics, including resistance to gastric acid and bile salts, biofilm formation and adherence to epithelium or mucus, amylase and protease activity and production of inhibitory compounds, were assessed. Read More

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Effect of Lactic Acid Bacteria Strains on the Growth and Aflatoxin Production Potential of , and Their Ability to Bind Aflatoxin B, Ochratoxin A, and Zearalenone .

Front Microbiol 2021 22;12:655386. Epub 2021 Apr 22.

Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, Brazil.

The increased consumption of plant-based foods has intensified the concern related to mycotoxin intoxication. This study aimed to investigate the effect of selected lactic acid bacteria (LAB) strains on the growth of NRRL 2999 and its production of aflatoxin (AF). The ability of the heat-killed (100°C for 1 h) LAB strains to bind aflatoxin M (AFM) in milk and aflatoxin B (AFB), ochratoxin A (OTA), and zearalenone (ZEN) in potassium phosphate buffer (PPB) was also evaluated . Read More

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Potential biomarkers of infertility associated with microbiome imbalances.

Am J Reprod Immunol 2021 May 6:e13438. Epub 2021 May 6.

Microgenesis Co, Detroit, MI, USA.

Problem: The aim of this study was to investigate the possible relationship between vaginal/rectal microbiome disbalances and miRNA expression with infertility.

Method Of Study: Observational, exploratory, preliminary study. A total of 287 multiple IVF failure infertile patients were recruited. Read More

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Diet, obesity, and the gut microbiome as determinants modulating metabolic outcomes in a non-human primate model.

Microbiome 2021 05 5;9(1):100. Epub 2021 May 5.

Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA.

Background: The objective of this study was to increase understanding of the complex interactions between diet, obesity, and the gut microbiome of adult female non-human primates (NHPs). Subjects consumed either a Western (n=15) or Mediterranean (n=14) diet designed to represent human dietary patterns for 31 months. Body composition was determined using CT, fecal samples were collected, and shotgun metagenomic sequencing was performed. Read More

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Effect of lactic acid fermentation of watermelon juice on its sensory acceptability and volatile compounds.

Food Chem 2021 Oct 19;358:129809. Epub 2021 Apr 19.

Research Unit VEG-i-TEC, Department of Food Technology, Safety and Health, Ghent University Campus Kortrijk, Graaf Karel de Goedelaan 5, 8500 Kortrijk, Belgium. Electronic address:

Fermentation increases food shelf-life but is characterized by changes that affect product's perception. Watermelon juice was fermented with Lactobacillus plantarum (WJ-LP), L. rhamnosus (WJ-LR), L. Read More

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October 2021

Probiotic-Derived Polyphosphate Accelerates Intestinal Epithelia Wound Healing through Inducing Platelet-Derived Mediators.

Mediators Inflamm 2021 29;2021:5582943. Epub 2021 Mar 29.

Division of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.

Inflammatory bowel disease (IBD), such as ulcerative colitis (UC) and Crohn's disease (CD), is an intractable intestinal inflammation associated with the disruption of the intestinal mucosa. We previously demonstrated that -derived long-chain polyphosphate (poly P) improved the intestinal barrier function by the upregulation of cell adhesion and relieved intestinal inflammation, thereby exerting a curing effect on colitis , , and in an investigator-initiated clinical study of UC. However, how poly P improves mucosal defects induced by intestinal inflammation has not been elucidated. Read More

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The lactic acid bacteria and yeast community of home-made sauerkraut from three provinces in Southwest China.

Arch Microbiol 2021 Aug 7;203(6):3171-3182. Epub 2021 Apr 7.

State Key Laboratory of Food Science and Technology, No. 235 Nanjing East Road, Nanchang, 330047, Jiangxi, People's Republic of China.

The aim of this study was to investigate the lactic acid bacteria (LAB) and yeast community from home-made sauerkraut collected from Southwest China through culture-dependent and culture-independent technology. Forty-eight samples of home-made sauerkraut were collected from households at three different locations in Southwest China. The pH, total acidity and salt contents among these fermented vegetables were 3. Read More

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Identification of Dairy Fungal Contamination and Reduction of Aflatoxin M1 Amount by Three Acid and Bile Resistant Probiotic Bacteria.

Arch Razi Inst 2021 Mar 1;76(1):119-126. Epub 2021 Mar 1.

Department of Food Microbiology, Faculty of Veterinary Specialized Science, Science and Research Branch, Tehran Central Branch, Islamic Azad University, Tehran, Iran.

Aflatoxins (AFs) released by fungi are observed in the cow’s milk even after pasteurization. Aflatoxin M1 (AFM1) has particularly an incredible clinical significance, as a critical carcinogenic agent for humans. Several strategies have been implemented for lowering the AFM1 amount, such as the employment of probiotics, particularly lactobacilli or lactic acid bacteria (LAB). Read More

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Fermented Gamma Aminobutyric Acid Improves Sleep Behaviors in Fruit Flies and Rodent Models.

Int J Mol Sci 2021 Mar 29;22(7). Epub 2021 Mar 29.

Department of Food Nutrition, Sangmyung University, Seoul 03016, Korea.

The aim of this study was to investigate the effect of -fermented γ-aminobutyric acid (LB-GABA) on sleep behaviors in invertebrate and vertebrate models. In , LB-GABA-treated group showed an 8-9%-longer sleep duration than normal group did. LB-GABA-treated group also showed a 46. Read More

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Effect of Different Fermentation Condition on Estimated Glycemic Index, In Vitro Starch Digestibility, and Textural and Sensory Properties of Sourdough Bread.

Foods 2021 Mar 1;10(3). Epub 2021 Mar 1.

Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul 34210, Turkey.

This study aimed to evaluate the influence of sourdough fermentation on the estimated glycemic index (eGI), in vitro starch digestibility, and textural and sensory properties of eight experimentally prepared sourdough breads. Wheat and whole wheat flour bread samples were produced under different fermentation conditions (25 °C and 30 °C) and fermentation methods (type-1 and type-2). In type-1 fermentation, sourdough was obtained via spontaneous fermentation. Read More

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Effects of Inoculants Producing Antifungal and Carboxylesterase Activities on Corn Silage and Its Shelf Life against Mold Contamination at Feed-Out Phase.

Microorganisms 2021 Mar 8;9(3). Epub 2021 Mar 8.

Division of Applied Life Science (BK21Four, Institute of Agriculture & Life Science), Gyeongsang National University, Jinju 52828, Korea.

The present study aimed to investigate effects of dual-purpose inoculants (antifungal and carboxylesterase activities) not only on corn silage quality, but also its shelf life against mold contamination at feed-out phase. Corn forage was ensiled for 252 d with different inoculants of the following: control (CON), 5M2 (5M), 6M1 (6M), and mixture of 5M and 6M at 1:1 ratio (MIX). After ensiling, corn silage was contaminated with . Read More

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Comparative profiling of lactic acid bacteria isolates in optimized and spontaneous fermentation of cowpea leaves.

Food Sci Nutr 2021 Mar 23;9(3):1651-1664. Epub 2021 Jan 23.

Department of Food Science, Nutrition and Technology University of Nairobi Nairobi Kenya.

In as much as spontaneous fermentation of cowpea leaves enhances product diversification, the process is rather slow with poor product quality. Limited work has been undertaken to provide input toward standardization of the process and enhancing of product quality. The current study sought to evaluate the in-process fermentative bacteria profile changes due to the effect of optimization of fermentation process of cowpea leaves. Read More

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