245 results match your criteria ksb

Vestibular performance in high-level soccer and ice hockey players: Sport-specific norm values and implications.

J Sci Med Sport 2021 Aug 13. Epub 2021 Aug 13.

Schulthess Klinik, Swiss Concussion Center, Switzerland; University Hospital Zurich, Clinical Neuroscience Center, Switzerland; University Hospital Zurich, Department of Neurology, Switzerland.

Objectives: Quantitative vestibular testing in athletes after sports-related concussion (SRC) has become more popular due to accompanying injuries of the peripheral-vestibular organs that require targeted treatment. Sports-specific normative values are currently not available. Taking into account potential adaptational mechanisms, we obtained sports-specific, age- and peak-head-velocity-corrected normative values of peripheral-vestibular function and postural-stability in football (soccer, FB) and ice-hockey (IH) players. Read More

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Successful salvage of recurrent leptomeningeal disease in large cell neuroendocrine lung cancer with stereotactic radiotherapy.

Strahlenther Onkol 2021 Aug 30. Epub 2021 Aug 30.

Radio-Onkologie-Zentrum KSA-KSB, Kantonsspital Aarau, Tellstrasse 25, 5001, Aarau, Switzerland.

A 70-year old male with stage I large cell neuroendocrine carcinoma (LCNEC) of the lung underwent resection of a metachronous 5 cm brain metastasis and received postoperative hypofractionated stereotactic radiotherapy (hfSRT). Five sequential nodular leptomeningeal metastases up to 5.3 cm in diameter were diagnosed on MRI within 10 months and were treated with SRT. Read More

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Consistency of 3D femoral torsion measurement from MRI compared to CT gold standard.

BMC Musculoskelet Disord 2021 Aug 28;22(1):739. Epub 2021 Aug 28.

Department of Orthopedics, Balgrist University Hospital, University of Zurich, Forchstrasse 340, 8008, Zurich, Switzerland.

Background: Several hip and knee pathologies are associated with aberrant femoral torsion. Diagnostic workup includes computed tomography (CT) and magnetic resonance imaging (MRI). For three-dimensional (3D) analysis of complex deformities it would be desirable to measure femoral torsion from MRI data to avoid ionizing radiation of CT in a young patient population. Read More

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Prediction of Myoelectric Biomarkers in Post-Stroke Gait.

Sensors (Basel) 2021 Aug 7;21(16). Epub 2021 Aug 7.

Center for Medical Convergence Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Korea.

Electromyography (EMG) is sensitive to neuromuscular changes resulting from ischemic stroke and is considered a potential predictive tool of post-stroke gait and rehabilitation management. This study aimed to evaluate the potential myoelectric biomarkers for the classification of stroke-impaired muscular activity of the stroke patient group and the muscular activity of the control healthy adult group. We also proposed an EMG-based gait monitoring system consisting of a portable EMG device, cloud-based data processing, data analytics, and a health advisor service. Read More

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Plate Fixation for Irreducible Proximal Humeral Fractures in Children and Adolescents-A Single-Center Case Series of Six Patients.

Children (Basel) 2021 Jul 26;8(8). Epub 2021 Jul 26.

Department of Orthopaedics and Traumatology, Kantonsspital Baden (KSB), Im Ergel 1, 5404 Baden, Switzerland.

Background: Recommended treatment for severely displaced proximal humeral fractures in children is the closed reduction and percutaneous fixation by K-wires or intramedullary nailing.

Methods: From January 2016 to January 2017 6, 21 children/adolescents (range 8 to 16 years) with proximal humeral fractures were treated surgically for severe displacement. In these six patients, several attempts of closed reduction were unsuccessful, and an open reduction was performed. Read More

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Risk Factors for Postoperative Urinary Retention After Endoscopic Hernia Repair: Age and Unilateral Operation make the Difference.

World J Surg 2021 Aug 23. Epub 2021 Aug 23.

Department of Surgery, Cantonal Hospital of Baden, Im Ergel 1, 5404, Baden, Switzerland.

Background: Postoperative urinary retention (POUR) is a common complication after inguinal hernia repair that may result in catheter-related infections or injuries, longer hospital stays, and thus, higher overall costs. Our aim was to assess the incidence of POUR after endoscopic total extraperitoneal (TEP) inguinal hernia repair and identify its risk factors.

Methods: We retrospectively analyzed all data that were included in a prospective Hernia Database for patients undergoing a TEP inguinal hernia repair at our institution between July 2012 and May 2018. Read More

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Quantitative Evaluation of Task-Induced Neurological Outcome after Stroke.

Brain Sci 2021 Jul 7;11(7). Epub 2021 Jul 7.

Center for Medical Convergence Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Korea.

Electroencephalography (EEG) can access ischemic stroke-derived cortical impairment and is believed to be a prospective predictive method for acute stroke prognostics, neurological outcome, and post-stroke rehabilitation management. This study aims to quantify EEG features to understand task-induced neurological declines due to stroke and evaluate the biomarkers to distinguish the ischemic stroke group and the healthy adult group. We investigated forty-eight stroke patients (average age 72. Read More

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Transfer of polyantimony units.

Chem Sci 2021 Jul 17;12(28):9726-9732. Epub 2021 Jun 17.

Institut für Anorganische Chemie, Universität Regensburg 93040 Regensburg Germany https://www.uni-regensburg.de/chemie-pharmazie/anorganische-chemie-scheer/.

Transfer reagents are useful tools in chemistry to access metastable compounds. The reaction of [Cp''ZrCl] with KSb(SiMe) leads to the formation of the novel polyantimony triple decker complex [(Cp''Zr)(μ,η-Sb)] (, Cp'' = 1,3-di-tertbutyl-cyclopentadienyl), containing a chair-like Sb ligand. Compound represents a valuable transfer reagent to form novel antimony ligand complexes. Read More

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DBP-GAPred: An intelligent method for prediction of DNA-binding proteins types by enhanced evolutionary profile features with ensemble learning.

J Bioinform Comput Biol 2021 Aug 21;19(4):2150018. Epub 2021 Jul 21.

Department of Computer Science, Abdul Wali Khan University Mardan, Pakistan.

DNA-binding proteins (DBPs) perform an influential role in diverse biological activities like DNA replication, slicing, repair, and transcription. Some DBPs are indispensable for understanding many types of human cancers (i.e. Read More

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NTCP Modeling of Late Effects for Head and Neck Cancer: A Systematic Review.

Int J Part Ther 2021 25;8(1):95-107. Epub 2021 Jun 25.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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Evaluating Factors Influencing Knowledge-Sharing Behavior of Students in Online Problem-Based Learning.

Front Psychol 2021 25;12:691755. Epub 2021 Jun 25.

Department of Industrial and Information Management, National Cheng Kung University, Tainan, Taiwan.

Adopting online problem-based learning (OPBL) to internship educational programs is an effective teaching method to stimulate self-directed and collaborative learning and knowledge-sharing behavior (KSB) of students. However, the OPBL collaboration experience is different from the traditional lecture-based learning experience for students. Integrating social identity theory and commitment-trust theory develops a formative research model that explains the KSB of students when using social media tools for the OPBL process. Read More

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[Spinal ozone therapy].

Radiologe 2021 Aug 9;61(8):736-741. Epub 2021 Jul 9.

Abteilung Neuroradiologie, Zentrum für Bildgebung, Kantonsspital Baden AG, Baden, Schweiz.

Clinical/methodological Problem: Technical advances in the field of spinal interventional neuroradiology allow the application of a wide range of targeted, minimally invasive treatment options including targeted spinal ozone therapy for back pain. This article provides an overview of the biochemical, molecular, immunologic, and pharmaceutical mechanisms and delivery techniques of targeted ozone therapy.

Standard Radiological Methods: Computed tomography (CT), conventional X‑ray (fluoroscopy). Read More

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Feasibility of Temperature Control by Electrical Impedance Tomography in Hyperthermia.

Cancers (Basel) 2021 Jun 30;13(13). Epub 2021 Jun 30.

Department of Information Technology and Electrical Engineering, Swiss Federal Institute of Technology (ETH), 8092 Zurich, Switzerland.

We present a simulation study investigating the feasibility of electrical impedance tomography (EIT) as a low cost, noninvasive technique for hyperthermia (HT) treatment monitoring and adaptation. Temperature rise in tissues leads to perfusion and tissue conductivity changes that can be reconstructed in 3D by EIT to noninvasively map temperature and perfusion. In this study, we developed reconstruction methods and investigated the achievable accuracy of EIT by simulating HT treatmentlike scenarios, using detailed anatomical models with heterogeneous conductivity distributions. Read More

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Deep Learning-Based Stroke Disease Prediction System Using Real-Time Bio Signals.

Sensors (Basel) 2021 Jun 22;21(13). Epub 2021 Jun 22.

Department of KSB Convergence Research, Electronics and Telecommunications Research Institute (ETRI), Daejeon 34129, Korea.

The emergence of an aging society is inevitable due to the continued increases in life expectancy and decreases in birth rate. These social changes require new smart healthcare services for use in daily life, and COVID-19 has also led to a contactless trend necessitating more non-face-to-face health services. Due to the improvements that have been achieved in healthcare technologies, an increasing number of studies have attempted to predict and analyze certain diseases in advance. Read More

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Can Dynamic Contrast-enhanced MRI Contribute to Improved Assessment of Rectosigmoid Involvement in Deep Infiltrating Endometriosis?

In Vivo 2021 Jul-Aug;35(4):2217-2226

Department of Radiology, Kantonsspital Baden, Baden, Switzerland.

Background/aim: To determine whether a prototypical compressed-sensing volume-interpolated breath-hold (csVIBE) provides diagnostic value in detecting rectosigmoid infiltration in deep infiltrating endometriosis (DIE).

Patients And Methods: csVIBE was employed in 151 women undergoing pelvic magnetic resonance imaging, of whom 43 had undergone surgery for suspected endometriosis. The accuracy of T2-weighted BLADE and BLADE/csVIBE, additional diagnostic value of csVIBE, and diagnostic confidence were rated by two readers. Read More

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Influence of potassium-solubilizing bacteria on the growth and radiocesium phyto-transfer of Brassica rapa L. var. perviridis grown in contaminated Fukushima soils.

J Environ Radioact 2021 Oct 17;237:106682. Epub 2021 Jun 17.

Institute of Agriculture, Tokyo University of Agriculture and Technology, Saiwaicho 3-5-8, Fuchu, Tokyo, 183-12 8509, Japan; The Faculty of Food and Agricultural Science, Fukushima University, Kanayagawa, Fukushima City, Fukushima, 960-1296, Japan.

The supply of K, being the chemical analog of Cs, affects the phytotransfer of radiocesium such as Cs from contaminated soils and its accumulation in plant tissues. Since K and Cs have high affinity to the same clay particle surfaces, the presence of potassium-solubilizing bacteria (KSB) could increase the availability of not only K in the rhizosphere but also of radiocesium. In this study, we obtained five KSB isolates with the highest solubilization capacities from soybean rhizosphere on modified Aleksandrov medium containing sericite as K source. Read More

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October 2021

Targeting Treatment Resistance in Head and Neck Squamous Cell Carcinoma - Proof of Concept for CT Radiomics-Based Identification of Resistant Sub-Volumes.

Front Oncol 2021 27;11:664304. Epub 2021 May 27.

Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Purpose: Radiomics has already been proposed as a prognostic biomarker in head and neck cancer (HNSCC). However, its predictive power in radiotherapy has not yet been studied. Here, we investigated a local radiomics approach to distinguish between tumor sub-volumes with different levels of radiosensitivity as a possible target for radiation dose intensification. Read More

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Focal unspecific bone uptake on [F]-PSMA-1007 PET: a multicenter retrospective evaluation of the distribution, frequency, and quantitative parameters of a potential pitfall in prostate cancer imaging.

Eur J Nucl Med Mol Imaging 2021 Jun 13. Epub 2021 Jun 13.

Department of Radiology and Nuclear Medicine, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.

Purpose: Improved logistics and availability led to a rapid increase in the use of [F]-PSMA-1007 for prostate cancer PET imaging. Initial data suggests increased uptake in benign lesions compared to [ Ga]-PSMA-11, and clinical observations found increased unspecific bone uptake (UBU). We therefore investigate the frequency and characteristics of UBU in [F]-PSMA-1007 PET. Read More

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ANOX: A robust computational model for predicting the antioxidant proteins based on multiple features.

Anal Biochem 2021 May 25:114257. Epub 2021 May 25.

College of Water Resources and Architectural Engineering, Northwest A&F University, Yangling, 712100, Shaanxi, China.

As an indispensable component of various living organisms, the antioxidant proteins have been studied for anti-aging and prevention of various diseases, such as altitude sickness, coronary heart disease, and even cancer. However, the traditional experimental methods for identifying the antioxidant proteins are very expensive and time-consuming. Thus, to address the challenge, a new predictor, named ANOX, was developed in this study. Read More

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Sequence Length of HIV-1 Subtype B Increases over Time: Analysis of a Cohort of Patients with Hemophilia over 30 Years.

Viruses 2021 04 30;13(5). Epub 2021 Apr 30.

HIV Databases, Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87544, USA.

We aimed to investigate whether the sequence length of HIV-1 increases over time. We performed a longitudinal analysis of full-length coding region sequences (FLs) during an HIV-1 outbreak among patients with hemophilia and local controls infected with the Korean subclade B of HIV-1 (KSB). Genes were amplified by overlapping RT-PCR or nested PCR and subjected to direct sequencing. Read More

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Reduced adrenal stress response in patients on PCSK9 inhibitor therapy.

Atherosclerosis 2021 05 31;325:63-68. Epub 2021 Mar 31.

Department of Internal Medicine, Cantonal Hospital Baden, Im Ergel 1, 5404, Baden, Switzerland; Laboratory for Platelet Research and of Endothelial Function, Center for Molecular Cardiology, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland. Electronic address:

Background And Aims: Treatment with proprotein convertase subtilisin-kexin type 9 inhibitors (PCSK9i), in addition to statin therapy, reduces LDL-cholesterol (LDL-c) in some patients to extremely low levels (i.e.< 20 mg/dl or < 0. Read More

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Isolation and screening of potassium solubilizing bacteria from saxicolous habitat and their impact on tomato growth in different soil types.

Arch Microbiol 2021 Aug 5;203(6):3147-3161. Epub 2021 Apr 5.

Root and Soil Biology Laboratory, Department of Botany, Bharathiar University, Coimbatore, Tamil Nadu, 641046, India.

Bacteria that solubilize nutrients in the soil are commonly used as bio-inoculants for promoting the growth of different crop species. However, the influence of potassium (K) solubilizing bacteria (KSB) originating from saxicolous habitat (rock-dwelling) on plant growth has not been frequently examined. In this study, we isolated KSB from saxicolous habitats and estimated their ability to produce plant growth hormone, organic acids, and siderophore that may facilitate plant growth. Read More

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Influences of potassium solubilizing bacteria and K-feldspar on enzyme activities and metabolic activities of the bacterial communities in kiwifruit planting soil.

J Gen Appl Microbiol 2021 Jul 31;67(3):106-113. Epub 2021 Mar 31.

Shaanxi Province Institute of Microbiology.

A pot experiment was conducted with kiwifruit planting soil to evaluate the impacts of potassium solubilizing bacteria (KSB) and K-feldspar on the soil nutrient levels, enzyme activities, and microecological environment. The effects were investigated of three inoculation treatments (T1: K-feldspar, T2: KSB, and T3: KSB with K-feldspar) and a non-inoculation treatment (CK) on the enzyme activities and the metabolic activities of the bacterial communities in kiwifruit rhizosphere soil. The results showed that the total nitrogen, available phosphorus, available potassium, and organic matter contents in T3 were 18. Read More

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Treatment planning facilitates clinical decision making for hyperthermia treatments.

Int J Hyperthermia 2021 01;38(1):532-551

Department of Radiation Oncology, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Treatment quality is important in clinical hyperthermia. Guideline-based treatment protocols are used to determine system settings and treatment strategies to ensure effective tumor heating and prevent unwanted treatment-limiting normal tissue hot spots. Realizing both these goals can prove challenging using generic guideline-based and operator-dependent treatment strategies. Read More

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January 2021

Does being exposed to an educational tool influence patient preferences? The influence of an educational tool on patient preferences assessed by a discrete choice experiment.

Patient Educ Couns 2021 Mar 10. Epub 2021 Mar 10.

Department of Public Health and Caring Sciences, Centre for Research Ethics & Bioethics, Uppsala University, Uppsala, Sweden. Electronic address:

Objectives: There is an increased interest in patient preferences informing the development and authorisation of medical products. A requirement for robust and meaningful results of such studies is that patients adequately understand the risks and benefits associated with treatments for which their preferences are elicited. This study aims to determine the influence of an educational tool, compared with traditional written information on patient preferences elicited in a discrete choice experiment (DCE). Read More

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Reduction of Sb(V) by coupled biotic-abiotic processes under sulfidogenic conditions.

Heliyon 2021 Feb 26;7(2):e06275. Epub 2021 Feb 26.

Biosciences Division, Argonne National Laboratory, Lemont, IL 60439-4843.

Increasing use and mining of antimony (Sb) has resulted in greater concern involving its fate and transport in the environment. Antimony(V) and (III) are the two most environmentally relevant oxidation states, but little is known about the redox transitions between the two in natural systems. To better understand the behavior of antimony in anoxic environments, the redox transformations of Sb(V) were studied in biotic and abiotic reactors. Read More

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February 2021

Quantification of thermal dose in moderate clinical hyperthermia with radiotherapy: a relook using temperature-time area under the curve (AUC).

Int J Hyperthermia 2021 ;38(1):296-307

Department of Radiation Oncology KSA-KSB, Kantonsspital Aarau, Aarau, Switzerland.

Background: Thermal dose in clinical hyperthermia reported as cumulative equivalent minutes (CEM) at 43 °C (CEM43) and its variants are based on direct thermal cytotoxicity assuming Arrhenius 'break' at 43 °C. An alternative method centered on the actual time-temperature plot during each hyperthermia session and its prognostic feasibility is explored.

Methods And Materials: Patients with bladder cancer treated with weekly deep hyperthermia followed by radiotherapy were evaluated. Read More

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The addition of deep hyperthermia to gemcitabine-based chemoradiation may achieve enhanced survival in unresectable locally advanced adenocarcinoma of the pancreas.

Clin Transl Radiat Oncol 2021 Mar 25;27:109-113. Epub 2021 Jan 25.

Centre for Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001 Aarau, Switzerland.

Introduction: Driven by the current unsatisfactory outcomes for patients with locally advanced pancreatic cancer (LAPC), a biologically intensified clinical protocol was developed to explore the feasibility and efficacy of FOLFORINOX chemotherapy followed by deep hyperthermia concomitant with chemoradiation and subsequent FOLFORINOX chemotherapy in patients with LAPC.

Methods: Nine patients with LAPC were treated according to the HEATPAC Phase II trial protocol which consists of 4 cycles of FOLFORINOX chemotherapy followed by gemcitabine-based chemoradiation to 56 Gy combined with weekly deep hyperthermia and then a further 8 cycles of FOLFORINOX chemotherapy.

Results: One grade three related toxicity was reported and two tumours became resectable. Read More

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[Spondylodiscitis and epidural abscesses].

Radiologe 2021 Mar 11;61(3):275-282. Epub 2021 Feb 11.

Abteilung Neuroradiologie, Zentrum für Bildgebung, Kantonsspital Baden AG, Im Ergel 1, 5404, Baden, Schweiz.

Clinical/methodological Problem: Spondylodiscitis is an inflammation of the intervertebral disc, which in adults is generally associated with spondylitis of the adjacent vertebrae. It often presents clinically with nonspecific symptoms such as back or neck pain. It may be caused by various pathogens, especially bacteria. Read More

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In Reply to Roussakow.

Int J Radiat Oncol Biol Phys 2021 02;109(2):642-644

Centre for Radiation Oncology KSA-KSB, Kantonsspital Aarau, Switzerland; Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.

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February 2021