874,545 results match your criteria knowledge


One year of COVID-19 pandemic: what we Radiologists have learned about imaging.

Rofo 2021 Oct 14. Epub 2021 Oct 14.

Radiology and Interventional Therapy, Vivantes-Klinikum Neukölln, Berlin, Germany.

Background:  Since its outbreak in December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has infected more than 151 million people worldwide. More than 3.1 million have died from Coronavirus Disease 2019 (COVID-19), the illness caused by SARS-CoV-2. Read More

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October 2021

Genetic and Epigenetic Control of Puberty.

Sex Dev 2021 Oct 14:1-10. Epub 2021 Oct 14.

Institute of Human Genetics, Faculty of Medicine, Pontificia Universidad Javeriana, Bogotá, Colombia.

Puberty is a complex transitional phase in which reproductive capacity is achieved. There is a very wide variation in the age range of the onset of puberty, which follows a familial, ethnic, and sex pattern. The hypothalamic-pituitary-gonadal axis and several genetic, environmental, and nutritional factors play an important role in the onset of and throughout puberty. Read More

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October 2021

Greenspace programmes for mental health: A survey study to test what works, for whom, and in what circumstances.

Health Place 2021 Oct 11;72:102669. Epub 2021 Oct 11.

Salvation Army Centre for Addiction Services and Research, Faculty of Social Sciences, University of Stirling, Stirling, FK9 4LA, Scotland, UK. Electronic address:

The health benefits of greenspace are widely acknowledged. Greenspace programmes, defined as health programmes undertaken in outside green areas such as parks, gardens, hills, and forests, are becoming more commonplace. However, there is still limited understanding of the mechanisms by which greenspace programmes are effective. Read More

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October 2021

Nation-wide hierarchical and spatially-explicit framework to characterize seagrass meadows in New-Caledonia, and its potential application to the Indo-Pacific.

Mar Pollut Bull 2021 Oct 11;173(Pt A):113036. Epub 2021 Oct 11.

UMR-9220 ENTROPIE (Institut de Recherche pour le Développement, Université de la Réunion, Ifremer, CNRS, Université de la Nouvelle-Calédonie), 101, promenade Roger-Laroque Anse Vata, BP A5, 98848 Noumea, New Caledonia.

Despite their ecological role and multiple contributions to human societies, the distribution of Indo-Pacific seagrasses remains poorly known in many places. Herein, we outline a hierarchical spatially-explicit assessment framework to derive nation-wide synoptic knowledge of the distribution of seagrass species and communities. We applied the framework to New Caledonia (southwest Pacific Ocean) and its 36,200 km of reefs and lagoons. Read More

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October 2021

An improved method for galactosyl oligosaccharide characterization.

J Chromatogr B Analyt Technol Biomed Life Sci 2021 Oct 4;1184:122967. Epub 2021 Oct 4.

Thermo Fisher Scientific, 1214 Oakmead Parkway, Sunnyvale, CA 94085, USA.

Due to beneficial effects of galactosyl oligosaccharides (GOS) on digestive and immune health, their characterization has become increasingly important. This is especially so as GOS are synthesized enzymatically and contain oligosaccharides of different sizes and linkages. High performance anion exchange chromatography with pulsed amperometric detection (HPAE-PAD) is widely used for GOS characterization. Read More

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October 2021

Changes in 6DOF knee kinematics during gait with decreasing gait speed.

Gait Posture 2021 Oct 8;91:52-58. Epub 2021 Oct 8.

Department of Orthopaedics, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong, China; School of Medicine, South China University of Technology, Guangzhou, 510006, China. Electronic address:

Background: Gait speed is recognized to correlate to knee kinematic alterations. Clinically, patients with knee diseases tend to walk slowly compared to healthy controls. Hence, gait speed may serve as a confounding factor in the kinematic characteristics of patients during gait compared to healthy controls. Read More

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October 2021

Unmet need in the management of chronic obstructive pulmonary disease in the Middle East and Africa region: An expert panel consensus.

Respir Med 2021 Oct 5;189:106641. Epub 2021 Oct 5.

Division of Pulmonology and UCT Lung Institute, Department of Medicine, University of Cape Town & Groote Schuur Hospital, Cape Town, South Africa.

Chronic obstructive pulmonary disease (COPD) has a significant impact on healthcare systems and health-related quality of life. Increased prevalence of smoking is an important factor contributing to high burden of COPD in the Middle East and Africa (MEA). Several other factors including sedentary lifestyle, urbanization, second-hand smoke, air pollution, and occupational exposure are also responsible for the upsurge of COPD in the MEA. Read More

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October 2021

Environmental hexavalent chromium exposure induces gut microbial dysbiosis in chickens.

Ecotoxicol Environ Saf 2021 Oct 11;227:112871. Epub 2021 Oct 11.

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:

Hexavalent chromium [Cr (VI)] is a hazardous heavy metal that pollutes soil, water and crops. Moreover, its prolonged exposure can harm the gastrointestinal system, liver and respiratory tract in different species, but knowledge regarding Cr (VI) influence on gut microbiota in chickens remains scarce. Therefore, this study was performed to investigate the impact of Cr (VI) on gut microbiota in chickens. Read More

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October 2021

Curium(III) speciation in the presence of microbial cell wall components.

Ecotoxicol Environ Saf 2021 Oct 12;227:112887. Epub 2021 Oct 12.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Resource Ecology, Bautzner Landstraße 400, 01328 Dresden, Germany.

Trivalent actinides such as Cm(III) are able to strongly interact with microbes and especially with bacterial cell walls. However, detailed knowledge of the influence of different cell wall components is somewhat lacking. For this investigation, we studied the formation of aqueous Cm(III) complexes with cell wall components (e. Read More

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October 2021

Development and evaluation of a telehealth-based simulation to improve breastfeeding education and skills among nursing students.

Nurse Educ Pract 2021 Oct 2;57:103226. Epub 2021 Oct 2.

Palm Beach Atlantic University, 901 S Flagler Dr, West Palm Beach, FL 33401, USA. Electronic address:

Aim: The aim of this study was to evaluate undergraduate nursing students' perceptions of using telehealth-based simulations for practicing their breastfeeding education skills.

Background: Telehealth can help bridge the gap between the high need for healthcare services and the limited access to these services, such as breastfeeding mothers in rural settings. However current literature suggests that there is lack of telehealth education among healthcare providers, as well as, a shortage of adequately trained nurses on breastfeeding, making it difficult to provide new mothers with the support they need to successfully breastfeed. Read More

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October 2021

Healthcare inequities among adults with developmental disability: An integrative review with implications for nursing education.

Nurse Educ Pract 2021 Oct 2;57:103225. Epub 2021 Oct 2.

M. Louise Fitzpatrick College of Nursing, Villanova University, Villanova, PA 19085, USA. Electronic address:

Aim: This integrative review synthesized research on the healthcare inequities experienced by adults with developmental disability in the United States and discussed implications for nursing education.

Background: Individuals with developmental disability are living longer with chronic comorbidities and experience healthcare inequities.

Method: Application of inclusion criteria to database and ancestry searches resulted in 26 articles that were assessed for quality and analyzed thematically. Read More

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October 2021

How does geriatric nursing education program change the knowledge, attitude and working intention among undergraduate nursing students? A systematic literature review.

Nurse Educ Today 2021 Sep 30;108:105161. Epub 2021 Sep 30.

School of Nursing, Faculty of Science, Medicine and Health, University of Wollongong, Northfields Ave, Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute (IHMRI), Northfields Ave, Wollongong, NSW 2522, Australia. Electronic address:

Objective: This review aimed to examine the changes of knowledge, attitude and working intention in nursing students after an undergraduate geriatric nursing education.

Design: A systematic review of the literature.

Data Sources: Five databases which included CINAHL, MEDLINE, PubMed, Scopus and Web of Science were searched for this literature review from January 2010 to October 2020. Read More

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September 2021

Biofilm with highly heterogeneous interior structure for pollutant removal: Cell distribution and manipulated mass transport.

Bioresour Technol 2021 Sep 8;343:125913. Epub 2021 Sep 8.

Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan; Department of Mechanical Engineering, City University of Hong Kong, Kowloon Tang, Hong Kong, China; College of Engineering, Tunghai University, Taichung 40704, Taiwan. Electronic address:

Biofilm wastewater treatment had been applied in practice. Conventionally the biofilm was modeled as a uniform structure to simplify the analysis. This study for the first time established a three-dimensional biofilm model with distributions separating living cells, Extracellular polymeric substances (EPS) and pores, based on which the local fluid flow velocity and pollutant diffusion and reaction fluxes inside the biofilm were numerically evaluated. Read More

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September 2021

Toward better drug discovery with knowledge graph.

Curr Opin Struct Biol 2021 Oct 11;72:114-126. Epub 2021 Oct 11.

Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education, School of Computer Science and Technology, Anhui University, Hefei, 230601, China.

Drug discovery is the process of new drug identification. This process is driven by the increasing data from existing chemical libraries and data banks. The knowledge graph is introduced to the domain of drug discovery for imposing an explicit structure to integrate heterogeneous biomedical data. Read More

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October 2021

Optimizing purification of the peripheral membrane protein FAM92A1 fused to a modified spidroin tag.

Protein Expr Purif 2021 Oct 11;189:105992. Epub 2021 Oct 11.

Department of Biomedical Engineering and Health Systems, Royal Technical Institute (KTH), Hälsovägen 11C, 141 2 Huddinge, Sweden. Electronic address:

Cryo-electron microscopy has revolutionized structural biology. In particular structures of proteins at the membrane interface have been a major contribution of cryoEM. Yet, visualization and characterization of peripheral membrane proteins remains challenging; mostly because there is no unified purification strategy for these proteins. Read More

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October 2021

Availability, use, and consumption practices of ready-to-use therapeutic foods prescribed to children with uncomplicated severe acute malnutrition aged 6-59 months during outpatient treatment in Burkina Faso.

Appetite 2021 Oct 11:105751. Epub 2021 Oct 11.

Expertise and Advocacy Department, Action contre la Faim, Paris, France.

Ready-to-use-therapeutic-foods (RUTF) was designed for the nutritional management of children with uncomplicated severe acute malnutrition (SAM) treated as outpatients. However, to our knowledge, no study has evaluated the availability, use and consumption of RUTF within the beneficiary household in programs and in the context of a reduction in the dose of RUTF. This study, assessed the effect of a reduction in RUTF dose on the availability, use, consumption, and perceptions of caregivers on RUTF prescribed to 516 children treated for SAM, aged 6-59 months in Burkina Faso. Read More

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October 2021

Towards reduced meat consumption: A systematic literature review of intervention effectiveness, 2001-2019.

Appetite 2021 Oct 11:105739. Epub 2021 Oct 11.

University of Natural Resources and Life Sciences, Institute of Marketing & Innovation, Feistmantelstrasse 4, 1180, Vienna, Austria. Electronic address:

A reduction of meat consumption and shift to plant-based diets, especially in industrialized countries, is acknowledged as crucial for reaching climate targets, addressing public health problems, and protecting animal welfare. While scholarly research distilled drivers of meat consumption and barriers to its reduction, insights into the effectiveness of measures to initiate such a profound change in consumer behaviour are relatively scarce. This paper presents a systematic literature review on consumption-side interventions in the context of meat consumption across scholarly disciplines. Read More

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October 2021

Theta band transcranial alternating current stimulation enhances arithmetic learning: A systematic comparison of different direct and alternating current stimulations.

Neuroscience 2021 Oct 11. Epub 2021 Oct 11.

Section of Educational Neuroscience, Institute of Psychology, University of Graz, Graz, Austria; BioTechMed Graz, Graz, Austria.

Over the last decades, interest in transcranial electrical stimulation (tES) has grown, as it might allow for causal investigations of the associations between cortical activity and cognition as well as to directly influence cognitive performance. The main objectives of the present work were to assess whether tES can enhance the acquisition and application of arithmetic abilities, and whether it enables a better assessment of underlying neurophysiological processes. To this end, the present, double-blind, sham-controlled study assessed the effects of six active stimulations (three tES protocols: anodal transcranial direct current stimulation (tDCS), alpha band transcranial alternating current stimulation (tACS), and theta band tACS; targeting the left dorsolateral prefrontal cortex or the left posterior parietal cortex) on the acquisition of an arithmetic procedure, arithmetic facts, and event-related synchronization/desynchronization (ERS/ERD) patterns. Read More

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October 2021

Antigen improves binding of IgGs to FcγRs in SPR analysis.

Authors:
Wei Wang Qing Chen

Anal Biochem 2021 Oct 12:114411. Epub 2021 Oct 12.

Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Dr., Thousand Oaks, CA, 91320, USA. Electronic address:

FcγR binding characterization is one of the critical attributes during the development of therapeutic antibodies. Here, we report a novel assay format to characterize IgG-FcγR interaction in the presence of antigen using Surface plasmon resonance (SPR). The new assay format was developed by creating stable antigen/antibody immunocomplexes on a sensor chip surface before injection of FcγRs. Read More

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October 2021

Genome-wide association study identifies multiple genetic loci for skin color in Korean women.

J Invest Dermatol 2021 Oct 11. Epub 2021 Oct 11.

Department of Core Technology, R&D Center, LG Household & Healthcare (LG H&H), Seoul 07795, Republic of Korea. Electronic address:

Human skin color is largely determined by genetic factors. Recent genome-wide association studies (GWAS) have reported several genetic variants associated with skin color, mostly in European and African populations. In this study, we performed GWAS in 17,019 Korean women to identify genetic variants associated with facial skin color, quantitatively measured as CIELAB color index. Read More

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October 2021

Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis.

J Am Med Dir Assoc 2021 Oct 11. Epub 2021 Oct 11.

Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

Objectives: High prevalence of delirium superimposed on dementia (DSD) was previously reported, with associated negative impact on hospitalized older adults. However, data were conflicting, and no meta-analysis has been conducted. Although dementia is the leading risk factor for delirium, risk factors for DSD have not been adequately studied. Read More

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October 2021

Horizon Scanning: Teaching Genomics and Personalized Medicine in the Digital Age.

OMICS 2021 Oct 13. Epub 2021 Oct 13.

The Golden Helix Foundation, London, United Kingdom.

Digital transformation is currently impacting not only health care but also education curricula for medicine and life sciences. The COVID-19 pandemic has accelerated the deployment of digital technologies such as the Internet of Things and artificial intelligence in diverse fields of biomedicine. Genomics and related fields of inquiry such as pharmacogenomics and personalized medicine have been making important progress over the past decades. Read More

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October 2021

Use and perception of complementary and alternative medicine among Iranian psychologists.

J Complement Integr Med 2021 Oct 14. Epub 2021 Oct 14.

Department of Health Education and Health Promotion, School of Health, Social Development and Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.

Objectives: The seeking and use of Complementary and Alternative Medicine (CAM) modalities by people to treat mental disorders has increased and it is necessary for psychologists to have the necessary information in this field. This study aims to evaluate the use and perception of CAM by Iranian psychologists.

Methods: This cross-sectional study was conducted on 100 psychologists selected by the census in 2019. Read More

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October 2021

Imaging flow cytometry reveals a subset of TdT negative T-ALL blasts with very low forward scatter on conventional flow cytometry.

Cytometry B Clin Cytom 2021 Oct 14. Epub 2021 Oct 14.

Department of Hematology, Aarhus University Hospital, Aarhus, Denmark.

Background: Studies in T-cell acute lymphoblastic leukemia (T-ALL) have shown that leukemic blast populations may display immunophenotypic heterogeneity. In the clinical setting, evaluation of measurable residual disease during treatment and follow-up is highly dependent on knowledge of the diversity of blast subsets. Here, we set out to evaluate whether variation in expression of the blast marker, TdT, in T-ALL blasts could correspond to differences in morphometric features. Read More

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October 2021

A Food Safety Education Needs Assessment for Small-Scale Produce Growers Interested in Value-Added Food Production.

J Food Prot 2021 Oct 14. Epub 2021 Oct 14.

Purdue University Assistant Professor Food Science 745 Agriculture Mall Dr. UNITED STATES West Lafayette In 47907 +15305742267.

Production of value-added foods is of growing interest to small-scale produce growers. However, previous studies reported that they lack sufficient food safety awareness and have limited knowledge of applicable food safety regulations. Targeted food safety education can help to address these challenges. Read More

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October 2021

Longitudinal trends in physician preferences for referrals to same-sex surgeons: a population-based study.

Br J Surg 2021 Oct 14. Epub 2021 Oct 14.

Institute of Health Policy, Management, and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

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October 2021

Knowledge, attitude and practice of hepatitis B infection prevention among nursing students in the Upper West Region of Ghana: A cross-sectional study.

PLoS One 2021 14;16(10):e0258757. Epub 2021 Oct 14.

Department of Health Services, Policy, Planning, Management and Economics, School of Public Health, University for Development Studies, Tamale, Northern Region, Ghana.

Introduction: Hepatitis B infection remains a public health threat associated with undesirable statistics of morbidity and mortality. Good knowledge, attitude and practice (KAP) of hepatitis B infection (HBI) prevention are essential for HBI control. However, there is limited evidence concerning the KAP of HBI prevention among nursing students, who are significantly exposed to HBI. Read More

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October 2021

General practice pharmacists in Australia: A systematic review.

PLoS One 2021 14;16(10):e0258674. Epub 2021 Oct 14.

Faculty of Health, Discipline of Pharmacy, University of Canberra, Bruce, Australian Capital Territory, Australia.

Background: The inclusion of pharmacists into general practices in Australia has expanded in recent years. This systematic review aimed to synthesise the literature of qualitative and quantitative studies, and identify the knowledge gaps, related to pharmacists working in general practice in Australia.

Methods: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Read More

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October 2021

Factors associated with nutritional status, knowledge and attitudes among tuberculosis patients receiving treatment in Ghana: A cross-sectional study in the Tema Metropolis.

PLoS One 2021 14;16(10):e0258033. Epub 2021 Oct 14.

Department of Population and Behavioural Sciences, School of Public Health (Hohoe Campus), University of Health and Allied Sciences, Ho, Ghana.

Background: Nutritional deficiencies are generally associated with increased risk and severity of tuberculosis. This study investigated the nutritional status, knowledge, and attitudes of tuberculosis (TB) patients receiving treatment in the Tema Metropolis.

Method: A cross-sectional design was used to collect data on the nutritional knowledge, attitude, and status of TB patients. Read More

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October 2021