380 results match your criteria kbs

Comparative analysis of ketone body metabolism in BALB/c mice infected with Trypanosoma evansi and Toxoplasma gondii.

Res Vet Sci 2021 Dec 20;143:134-141. Epub 2021 Dec 20.

Key Laboratory of Livestock Infectious Diseases, Ministry of Education, China; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China. Electronic address:

KBs (ketone bodies), i.e., acetoacetate, acetone, and (R)-3-Hydroxybutanoate, constitute the intermediate products of the incomplete oxidative degradation of fatty acids. Read More

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December 2021

Biomedical relation extraction via knowledge-enhanced reading comprehension.

BMC Bioinformatics 2022 Jan 6;23(1):20. Epub 2022 Jan 6.

Intelligent Computing Research Center, Harbin Institute of Technology (Shenzhen), Shenzhen, China.

Background: In biomedical research, chemical and disease relation extraction from unstructured biomedical literature is an essential task. Effective context understanding and knowledge integration are two main research problems in this task. Most work of relation extraction focuses on classification for entity mention pairs. Read More

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January 2022

How COVID-19 affects the use of evidence informed policymaking among iranian health policymakers and managers.

Arch Public Health 2022 Jan 5;80(1):16. Epub 2022 Jan 5.

Menzies Centre for Health Policy and Economics, Sydney School of Public Health, University of Sydney, Sydney, Australia.

Background: The COVID-19 pandemic increased the need for new valid scientific evidence to support urgent clinical and policy decision making; as well as improved processes for the rapid synthesis, uptake and application of that evidence. Evidence informed policymaking (EIPM) can be considered as a way to access and use the results of evidence in practice. This study aimed to determine what effects COVID-19 had on the way Iranian health managers and policymakers use evidence in their decisions. Read More

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January 2022

The roles, activities and impacts of middle managers who function as knowledge brokers to improve care delivery and outcomes in healthcare organizations: a critical interpretive synthesis.

BMC Health Serv Res 2022 Jan 2;22(1):11. Epub 2022 Jan 2.

University Health Network, 13EN-228, 200 Elizabeth Street, Toronto, Ontario, M5G 2C4, Canada.

Background: Middle Managers (MMs) are thought to play a pivotal role as knowledge brokers (KBs) in healthcare organizations. However, the role of MMs who function as KBs (MM KBs) in health care is under-studied. Research is needed that contributes to our understanding of how MMs broker knowledge in health care and what factors influence their KB efforts. Read More

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January 2022

A Cost Modelling System for Recycling Carbon Fiber-Reinforced Composites.

Polymers (Basel) 2021 Dec 1;13(23). Epub 2021 Dec 1.

Design, Manufacturing and Production Engineering Section, Department of Mechanical and Production Engineering, Aarhus University, 8000 Aarhus, Denmark.

Cost-effective and environmentally responsible ways of carbon fiber-reinforced composite (CFRP) recycling are increasingly important, owing to the rapidly increasing use of these materials in many industries such as the aerospace, automotive and energy sectors. Product designers need to consider the costs associated with manufacturing and the end-of-life stage of such materials to make informed decisions. They also need to understand the current methods of composite recycling and disposal and their impact on the end-of-life costs. Read More

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December 2021

Novel UBE3A pathogenic variant in a large Georgian family produces non-convulsive status epilepticus responsive to ketogenic diet.

Seizure 2022 Jan 24;94:70-73. Epub 2021 Nov 24.

AdPueriVitam, Antony, France.

Purpose: To report the effect of the ketogenic diet (KD) on non-convulsive status epilepticus (NCSE) due to Angelman syndrome (AS) in two members of a large Georgian family affected by a novel frameshift variant in the UBE3A gene (NM_000462.3).

Methods: We evaluated two members of this family who were affected with clinical and EEG features of AS. Read More

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January 2022

Endothelial Heme Dynamics Drive Cancer Cell Metabolism by Shaping the Tumor Microenvironment.

Biomedicines 2021 Oct 28;9(11). Epub 2021 Oct 28.

Molecular Biotechnology Center (MBC), Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.

The crosstalk among cancer cells (CCs) and stromal cells within the tumor microenvironment (TME) has a prominent role in cancer progression. The significance of endothelial cells (ECs) in this scenario relies on multiple vascular functions. By forming new blood vessels, ECs support tumor growth. Read More

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October 2021

Interference of ketone bodies on laboratory creatinine measurement in children with DKA: a call for change in testing practices.

Pediatr Nephrol 2021 Nov 10. Epub 2021 Nov 10.

Dept of Pathology and Laboratory Medicine, BC Children's & Women's Hospital, University of British Columbia, 4480 Oak Street, Room 2J9, Vancouver, BC, V6H 3N1, Canada.

Background: The presence of ketone bodies (KBs) can interfere with creatinine (Cr) measurement in both enzymatic and Jaffe methods. Since a high proportion of children hospitalized for diabetic ketoacidosis (DKA) develop acute kidney injury (AKI), here we investigate whether KB interferences affect the accuracy of pediatric Cr measurement.

Methods: Residual patient plasma samples were pooled to make three Cr levels (~ 50, 100, and 250 μM). Read More

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November 2021

Knowledge-Based Reasoning Network for Relation Detection.

IEEE Trans Neural Netw Learn Syst 2021 Nov 9;PP. Epub 2021 Nov 9.

With the rapid growth of large-scale knowledge bases (KBs), knowledge base question answering (KBQA) has attracted increasing attention recently. Relation detection plays an important role in the KBQA system, which finds a compatible answer by analyzing the semantics of questions and querying and reasoning with multiple KB triples. Significant progress has been made by deep neural networks. Read More

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November 2021

Is there a relationship between the ketogenic diet and sleep disorders?

Int J Food Sci Nutr 2021 Oct 26:1-11. Epub 2021 Oct 26.

Centro Italiano per la cura e il Benessere del paziente con Obesità (C.I.B.O), Department of Clinical Medicine and Surgery, Endocrinology Unit, University Medical School of Naples, Naples, Italy.

Sleep disorders are very often underestimated and, consequently, not treated with due priority. Common sleep disorders include insomnia disorders, sleep-related breathing disorders, central disorders of hypersomnolence, circadian rhythm sleep-wake disorders, sleep-related movement disorders, parasomnias, and other sleep disorders. The ketogenic diet (KD) is rich in fat, low in carbohydrates (CHO), and adequate in protein. Read More

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October 2021

[Coefficient of biomechanical stress in assessment of the degree of intraocular pressure compensation].

Vestn Oftalmol 2021 ;137(5. Vyp. 2):255-261

Research Institute of Eye Diseases, Moscow, Russia.

Intraocular pressure is the one modifiable factor, which correct assessment and normalization initiates the treatment of glaucoma. The accuracy of its measurement by traditional methods depends on biomechanical properties of the fibrous tunic of the eye, which in modern clinical practice are most successfully studied by the method of bidirectional applanation of the cornea using the Ocular Response Analyzer (ORA). Mathematical integration of the parameters it measures makes it possible to calculate the coefficient of biomechanical stress (K) that characterizes changes in the fibrous tunic of the eye induced by intraocular pressure, and serves as a criterion for intraocular pressure compensation. Read More

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October 2021

Evaluation of Anticaries Efficacy of Various Fluoride Varnishes on Artificial Enamel Lesion: An Study.

J Contemp Dent Pract 2021 Jul 1;22(7):774-777. Epub 2021 Jul 1.

Department of Public Health Dentistry, Mar Baselios Dental College, Kothamangalam, Kerala, India.

Aim: Aim of the current study was to assess the anticariogenic effectiveness of different fluoride varnishes on artificially induced enamel lesions employing scanning electron microscope.

Materials And Methods: Eighty healthy, normal premolars without dental caries that were extracted in course of orthodontic therapy with all the surfaces intact were included in this study. A window, 4 × 4 mm, was made discernible on the buccal surface of each sample tooth. Read More

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Profiling knowledge brokers in the rehabilitation sector across Canada: A descriptive study.

J Eval Clin Pract 2021 Oct 6. Epub 2021 Oct 6.

McGill University, School of Physical and Occupational Therapy, The Centre for Interdisciplinary Research in Rehabilitation of Greater Montréal (CRIR), Montreal, Québec, Canada.

Rationale: Knowledge brokers (KBs) can help promote the uptake of the latest research evidence into clinical practice. Little is known about who they are, the types of roles they perform, and the training they receive. Establishing a portrait of Canadian KBs working in the rehabilitation sector may inform health care organizations and knowledge translation specialists on how best to advance KBs practices. Read More

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October 2021

Association of Circulating Ketone Bodies With Functional Outcomes After ST-Segment Elevation Myocardial Infarction.

J Am Coll Cardiol 2021 10;78(14):1421-1432

Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

Background: Circulating ketone bodies (KBs) are increased in patients with heart failure (HF), corresponding with increased cardiac KB metabolism and HF severity. However, the role of circulating KBs in ischemia/reperfusion remains unknown.

Objectives: This study sought to investigate longitudinal changes of KBs and their associations with functional outcomes in patients presenting with ST-segment elevation myocardial infarction (STEMI). Read More

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October 2021

Continual Knowledge Infusion into Pre-trained Biomedical Language Models.

Bioinformatics 2021 Sep 23. Epub 2021 Sep 23.

Department of Computer Science, University of Virginia, Charlottesville, VA, 22903, USA.

Motivation: Biomedical language models produce meaningful concept representations that are useful for a variety of biomedical natural language processing (bioNLP) applications such as named entity recognition, relationship extraction, and question answering. Recent research trends have shown that the contextualized language models (e.g. Read More

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September 2021

Kluver-Bucy Syndrome: A Rare Complication of Herpes Simplex Encephalitis.

Eur J Case Rep Intern Med 2021 22;8(7):002725. Epub 2021 Jul 22.

Unidade Local Saúde Alto Minho, Hospital Conde de Bertiandos, Ponte de Lima, Portugal.

Kluver-Bucy syndrome (KBS) is a characterized by a group of cognitive dysfunctions that include hypersexuality, placidity, hyperorality, memory deficits and hypermetamorphosis. This syndrome is often seen in pathological states that destroy the temporal lobes, normally bilaterally. Herpes simplex encephalitis (HSE) is one of the causes of KBS, as the herpes virus can cause dysfunction/destruction of the temporal lobes. Read More

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Identification and Characterization of s Mutations Associated With Early Blooming in Sweet Cherry, and Validation of DNA-Based Markers for Selection.

Front Plant Sci 2021 8;12:621491. Epub 2021 Jul 8.

Unidad de Hortofruticultura, Centro de Investigación y Tecnología Agroalimentaria de Aragón, Zaragoza, Spain.

Dormancy release and bloom time of sweet cherry cultivars depend on the environment and the genotype. The knowledge of these traits is essential for cultivar adaptation to different growing areas, and to ensure fruit set in the current climate change scenario. In this work, the major sweet cherry bloom time QTL (327 Kbs; Chromosome 1) was scanned for candidate genes in the Regina cv genome. Read More

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Successful Combination Therapy of Trazodone and Fluvoxamine for Pica in Alzheimer's Disease: A Case Report.

Front Psychiatry 2021 1;12:704847. Epub 2021 Jul 1.

Department of Psychiatry, Nihon University School of Medicine, Tokyo, Japan.

Pica in Alzheimer's disease (AD) makes it difficult for caregivers to provide care. However, few effective medications have been reported for pica in AD. We report a case of AD with pica that was successfully improved by trazodone and fluvoxamine. Read More

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Ketogenic diets, physical activity, and body composition: A review.

Br J Nutr 2021 Jul 12:1-68. Epub 2021 Jul 12.

Department of Biomedical Sciences, University of Padua, Padua, Italy.

Obesity remains a serious relevant public health concern throughout the world despite related countermeasures being well understood (i.e., mainly physical activity and an adjusted diet). Read More

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Influence of Foliar Silicic Acid Application on Soybean ( L.) Varieties Grown across Two Distinct Rainfall Years.

Plants (Basel) 2021 Jun 8;10(6). Epub 2021 Jun 8.

Department of Soil Science and Agricultural Chemistry, University of Agricultural Sciences, Bangalore, Karnataka 560 065, India.

The foliar nutrition of silicic acid is considered to be a novel approach in enhancing the performance of many crops worldwide. The present study aimed to assess if the foliar application of silicon (Si) could influence the performance of soybean varieties with distinct crop duration, MAUS-2 (long duration) and KBS-23 (short duration). Field experiments were conducted in two consecutive years (2016 and 2017) of varied rainfall with foliar application of silicic acid @ 2 and 4 mL L for three and two sprays each. Read More

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A Novel Lightweight Deep Learning-Based Histopathological Image Classification Model for IoMT.

Neural Process Lett 2021 Jun 8:1-24. Epub 2021 Jun 8.

Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology, School of Mathematics and Big Data, Foshan University, Foshan, 528000 China.

The unavailability of appropriate mechanisms for timely detection of diseases and successive treatment causes the death of a large number of people around the globe. The timely diagnosis of grave diseases like different forms of cancer and other life-threatening diseases can save a valuable life or at least extend the life span of an afflicted individual. The advancement of the Internet of Medical Things (IoMT) enabled healthcare technologies can provide effective medical facilities to the population and contribute greatly towards the recuperation of patients. Read More

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Regulatory and Technical Constraints: An Overview of the Technical Possibilities and Regulatory Limitations of Vehicle Telematic Data.

Sensors (Basel) 2021 May 18;21(10). Epub 2021 May 18.

Kemmy Business School (KBS), University of Limerick, V94 T9PX Limerick, Ireland.

A telematics device is a vehicle instrument that comes preinstalled by the vehicle manufacturer or can be added later. The device records information about driving behavior, including speed, acceleration, and turning force. When connected to vehicle computers, the device can also provide additional information regarding the mechanical usage and condition of the vehicle. Read More

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The Value of Ketone Bodies in the Evaluation of Kidney Function in Patients with Type 2 Diabetes Mellitus.

J Diabetes Res 2021 10;2021:5596125. Epub 2021 Apr 10.

Department of Endocrinology, The First Affiliated Hospital of Fujian Medical University, 20 Cha Zhong Road, Fuzhou, Fujian 350005, China.

Objectives: Recent studies have shown that the slightly elevated circulating levels of ketone bodies (KBs) played a significant role in the treatment of various diseases. This study is aimed at investigating the association between different levels of KBs and kidney function in patients with type 2 diabetes mellitus (T2DM).

Methods: A retrospective study of 955 patients with T2DM (426 women and 529 men) admitted to our hospital from December 2017 to September 2019 was conducted. Read More

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December 2021

Nationwide Environmental Scan of Knowledge Brokers Training.

J Contin Educ Health Prof 2021 May 6. Epub 2021 May 6.

Dr. Gaid: McGill University, School of Physical and Occupational Therapy, and The Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal (CRIR), Montreal, Quebec, Canada. Dr. Mate: Postdoctoral Fellow, Centre for Outcomes Research and Evaluation, McGill University Health Centre Research Institute, and the Centre for Interdisciplinary Research in Rehabilitation of Greater Montréal (CRIR), Montreal, Quebec, Canada. Dr. Ahmed: Associate Professor, McGill University, School of Physical and Occupational Therapy, and the Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal (CRIR), Montreal, Quebec, Canada. Dr. Thomas: Associate Professor, McGill University, School of Physical and Occupational Therapy, and the Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal (CRIR), Montreal, Quebec, Canada. Dr. Bussières: Professor Titulaire, Département chiropratique, Université du Québec à Trois-Rivières, Assistant Professor, McGill University, School of physical and occupational therapy, and the Centre for Interdisciplinary Research in Rehabilitation of Greater Montréal (CRIR), Montreal, Quebec, Canada.

Introduction: Knowledge brokers (KBs) can promote the uptake of best practice guidelines in rehabilitation. Although many institutions offer training opportunities to health care professionals who wish to undertake KBs roles, the characteristics and content of those educational training opportunities (ETOs) are currently unknown. This study aimed to describe the ETOs available to rehabilitation professionals in Canada and determine whether the ETOs meet the competencies expected of the KBs roles. Read More

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Impurity-driven transitions in frustrated quantum Ising rings.

Phys Rev E 2021 Mar;103(3-1):032129

College of Physics and Key Laboratory of High Energy Density Physics and Technology of Ministry of Education, Sichuan University, 610064 Chengdu, People's Republic of China.

We study the quantum phase transition driven by a point impurity in a chain seamed with ring frustration. With strong coupling and light impurity, the system is in a topological extended-kink (TEK) phase, which exhibits gapless excitations in the bulk. With strong coupling and heavy impurity, the system is in a gapped kink bound state (KBS) phase. Read More

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Amorphous to Crystal Phase Change Memory Effect with Two-Fold Bandgap Difference in Semiconducting KBiSe.

J Am Chem Soc 2021 Apr 15;143(16):6221-6228. Epub 2021 Apr 15.

Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.

Chalcogenide-based phase change memory (PCM) is a key enabling technology for optical data storage and electrical nonvolatile memory. Here, we report a new phase change chalcogenide consisting of a 3D network of ionic (K···Se) and covalent bonds (Bi-Se), KBiSe (KBS). Thin films of amorphous KBS deposited by DC sputtering are structurally and chemically homogeneous and exhibit a surface roughness of 5 nm. Read More

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New hominin remains and revised context from the earliest Homo erectus locality in East Turkana, Kenya.

Nat Commun 2021 04 13;12(1):1939. Epub 2021 Apr 13.

Paleomagnetic Laboratory 'Fort Hoofddijk', Utrecht University, Utrecht, Netherlands.

The KNM-ER 2598 occipital is among the oldest fossils attributed to Homo erectus but questions have been raised about whether it may derive from a younger horizon. Here we report on efforts to relocate the KNM-ER 2598 locality and investigate its paleontological and geological context. Although located in a different East Turkana collection area (Area 13) than initially reported, the locality is stratigraphically positioned below the KBS Tuff and the outcrops show no evidence of deflation of a younger unit, supporting an age of >1. Read More

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MAternal Mental Health in the WORKplace ([email protected]): A Protocol for Promoting Perinatal Maternal Mental Health and Wellbeing.

Int J Environ Res Public Health 2021 03 4;18(5). Epub 2021 Mar 4.

Instituto de Saúde Ambiental, Faculdade de Medicina da Universidade de Lisboa, 1649-028 Lisboa, Portugal.

Women are exposed to increased burden of mental disorders during the perinatal period: 13-19% experience postpartum depression. Perinatal psychological suffering affects early mother-child relationship, impacting child's emotional and cognitive development. Return-to-work brings additional vulnerability given the required balance between parenting and job demands. Read More

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A multicenter trial of current trends in the diagnosis and management of high-grade pancreatic injuries.

J Trauma Acute Care Surg 2021 05;90(5):776-786

From the Scripps Memorial Hospital La Jolla (WLB, FZZ, MC, KBS), La Jolla, CA; Maine Medical Center (BM), Portland, ME; Memorial Hermann Hospital (MM), Houston, TX; University of Oklahoma (JL), Oklahoma City, OK; Ryder Trauma Center (SB), Miami, FL; University of California-San Diego (JW), San Diego, CA; San Francisco General Hospital (RC, LK), San Francisco, CA; University of Calgary (CCGB), Calgary, Alberta, Canada; University of California-Irvine (JN), Irvine, CA; North Memorial Health Hospital (MW), Robbinsdale, MN; University of California-Davis (GJJ), Sacramento, CA; Grady Memorial Hospital (SRT), Atlanta, GA; Hadassah- Hebrew University Medical Center (MB), Jerusalem, Israel; Grant Medical Center (CS), Columbus, OH; Ernest E. Moore Shock Trauma Center at Denver Health (EEM), Denver, CO.

Background: Outcomes following pancreatic trauma have not improved significantly over the past two decades. A 2013 Western Trauma Association algorithm highlighted emerging data that might improve the diagnosis and management of high-grade pancreatic injuries (HGPIs; grades III-V). We hypothesized that the use of magnetic resonance cholangiopancreatography, pancreatic duct stenting, operative drainage versus resection, and nonoperative management of HGPIs increased over time. Read More

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Kidney Biopsy in Type 2 Diabetes: A Multicenter Cross-Sectional Study.

Am J Nephrol 2021 29;52(2):131-140. Epub 2021 Mar 29.

Université de Paris, Paris, France.

Introduction: Kidney biopsies (KBs) are performed in patients with type 2 diabetes (T2D) to diagnose non-diabetic or hypertensive kidney disease (NDHKD) potentially requiring specific management compared to diabetic and or hypertensive nephropathy (absence of NDHKD). Indications for KB are based on the presence of atypical features compared to the typical course of diabetic nephropathy. In this study, we assessed the association of different patterns of atypical features, or KB indications, with NDHKD. Read More

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November 2021