17,895 results match your criteria june 2020


Penetrating Keratoplasty - Indications in a tertiary care center in Nepal.

Nepal J Ophthalmol 2020 Jul;12(24):252-261

B. P. Koirala Centre for Ophthalmic Studies (BPKLCOS), Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.

Introduction: Penetrating keratoplasty has become one of the most commonly performed transplant procedures where full thickness diseased host corneal tissue is replaced with healthy donor corneal tissue. Aims of penetrating keratoplasty include improvement in visual acuity, removal of infectious load, alleviate pain or even to simply save the anatomy of the eye. Visual improvement and removal of infection is the prime objective of majority of corneal grafts. Read More

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Molecular diagnosis for the novel coronavirus SARS-CoV-2: lessons learnt from the Ghana experience.

Ghana Med J 2020 Dec;54(4 Suppl):77-85

Department of Virology, University of Ghana, Noguchi Memorial Institute for Medical Research, Legon, Ghana.

Background: A novel coronavirus, SARS-CoV-2 is currently causing a worldwide pandemic. The first cases of SARS-CoV-2 infection were recorded in Ghana on March 12, 2020. Since then, the country has been combatting countrywide community spread. Read More

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December 2020

COVID-19 autopsy reports from the Ga-East Municipal and the 37 Military Hospitals in Accra, Ghana.

Ghana Med J 2020 Dec;54(4 Suppl):52-61

Department of Pathology, School of Medical Sciences, University of Cape Coast and Cape Coast Teaching Hospital, Cape Coast, Ghana.

Introduction: Since the declaration of COVID-19 by the World Health Organisation (WHO) as a global pandemic on 11th March 2020, the number of deaths continue to increase worldwide. Reports on its pathologic manifestations have been published with very few from the Sub-Saharan African region. This article reports autopsies on COVID-19 patients from the Ga-East and the 37 Military Hospitals to provide pathological evidence for better understanding of COVID-19 in Ghana. Read More

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December 2020

Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana.

Ghana Med J 2020 Dec;54(4 Suppl):39-45

Department of Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Background: In high-income countries, mortality related to hospitalized patients with the Coronavirus disease 2019 (COVID-19) is approximately 4-5%. However, data on COVID-19 admissions from sub-Saharan Africa are scanty.

Objective: To describe the clinical profile and determinants of outcomes of patients with confirmed COVID-19 admitted at a hospital in Ghana. Read More

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December 2020

Epidemiology of COVID-19 outbreak in Ghana, 2020.

Ghana Med J 2020 Dec;54(4 Suppl):5-15

Department of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana.

Objective: Describe the epidemiology of COVID-19 cases detected in the first four months of the pandemic in Ghana by person, place and time to provide an understanding of the local epidemiology of the disease.

Methods: We conducted an exploratory descriptive study of all confirmed COVID-19 cases in Ghana from March 12 to June 30, 2020. Data was merged from the country's electronic databases, cleaned and summarized using medians, proportions and geospatial analysis. Read More

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December 2020

Cotrimoxazole for community-acquired urinary tract infections leads to more adverse effects than fluoroquinolones.

Infect Dis Now 2021 Jun 30;51(4):374-376. Epub 2020 Dec 30.

Infectiologie, centre hospitalier universitaire, route de Chauvel, 97139 Les Abymes, Guadeloupe, France; Faculté de médecine, université des Antilles, Fouillole, 97110 Pointe-à-Pitre, Guadeloupe, France. Electronic address:

Background: For several years, we applied an internal guideline for community-acquired urinary tract infections (cUTI), targeting the reduction of fluoroquinolone use (FQ) and thereby favouring cotrimoxazole (CTM) prescription. Our aim was to report adverse effects (AE) and outcome for patients presenting with cUTI and treated with these compounds.

Methods: This cohort study was based on the dashboard of our department, bringing together 28 parameters for all patients, including diagnosis, microbiological data, antibiotic therapy, AE, length of hospital stay (LHS) and outcome. Read More

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Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review.

Cochrane Database Syst Rev 2020 09 15;9:CD013574. Epub 2020 Sep 15.

Cochrane Austria, Department for Evidence-based Medicine and Evaluation, Danube University Krems, Krems, Austria.

Background: Coronavirus disease 2019 (COVID-19) is a rapidly emerging disease classified as a pandemic by the World Health Organization (WHO). To support the WHO with their recommendations on quarantine, we conducted a rapid review on the effectiveness of quarantine during severe coronavirus outbreaks.

Objectives: To assess the effects of quarantine (alone or in combination with other measures) of individuals who had contact with confirmed or suspected cases of COVID-19, who travelled from countries with a declared outbreak, or who live in regions with high disease transmission. Read More

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September 2020

Clinical Features and Outcomes of ICU Patients with COVID-19 Infection in Tehran, Iran: a Single-Centered Retrospective Cohort Study.

Tanaffos 2020 Dec;19(4):300-311

Clinical Tuberculosis and Epidemiology Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: The clinical characteristics of the novel coronavirus disease (COVID-19) were diverse and unspecific. Here, we identified the associated factors with surviving of COVID-19 ICU patients based on the clinical characteristics of patients admitted to one of the Corona Centre Hospitals of Iran.

Materials And Methods: This cohort study was performed retrospectively from February to June 2020 on 133 COVID-19 patients admitted to 4 intensive care units of Masih Daneshvari Hospital in Tehran, Iran. Read More

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December 2020

Obituary: Prof. Dr. med. Dr. phil. Horst Kächele, Ulm, a messenger of empirical research in psychoanalysis (born 18 February1944, died 28 June 2020).

Int J Psychoanal 2020 Dec;101(6):1264-1270

University Clinic of Psychosomatic Medicine and Psychotherapy, Section Forensic Psychotherapy, Ulm, Germany.

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December 2020

The 'wave sign' in hip arthroscopy: a systematic review of epidemiological factors, current diagnostic methods and treatment options.

J Hip Preserv Surg 2020 Aug 22;7(3):410-422. Epub 2020 Dec 22.

Department of Orthopaedic Surgery, Maroondah Hospital, Ringwood, Victoria, Australia.

This study aims to present a systematic review and synthesized evidence on the epidemiological factors, diagnostic methods and treatment options available for this phenomenon. A multi-database search (OVID Medline, EMBASE and PubMed) was performed according to PRISMA guidelines on 18 June 2019. All studies of any study design discussing on the epidemiological factors, diagnostic methods, classification systems and treatment options of the wave sign were included. Read More

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Is continuity of primary care declining in England? Practice-level longitudinal study from 2012 to 2017.

Br J Gen Pract 2020 Dec 14. Epub 2020 Dec 14.

Centre for Academic Primary Care, University of Bristol, Bristol.

Background: Continuity of care is a core principle of primary care related to improved patient outcomes and reduced healthcare costs. Evidence suggests continuity of care in England is declining.

Aim: To confirm reports of declining continuity of care, explore differences in decline according to practice characteristics, and examine associations between practice populations or appointment provision and changes in continuity of care. Read More

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December 2020

CT-scan Based Liver and Spleen Volume Measurement as a Prognostic Indicator for Patients with Cirrhosis.

Am J Med Sci 2020 Nov 2. Epub 2020 Nov 2.

Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, United States; Roudebush Veterans Administration Medical Center, Indianapolis, IN, United States; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, United States. Electronic address:

Background: Complications of patients with liver disease generally occurs as the consequence of advanced fibrosis and portal hypertension. Non-invasive tools to predict the complications may allow for better risk-stratification and medical management in patients with cirrhosis. The goals of this study were to determine the utility of CT-scan based liver and spleen volume measurement in association with complications and outcomes in patients with cirrhosis. Read More

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November 2020

Child health services during a COVID-19 outbreak in KwaZulu-Natal Province, South Africa.

S Afr Med J 2020 12 15;111(2):114-119. Epub 2020 Dec 15.

Health Systems Strengthening Unit, Health Systems Trust, Durban, South Africa.

Background: Current evidence indicates that children are relatively spared from direct COVID-19-related morbidity and mortality, but that the indirect effects of the pandemic pose significant risks to their health and wellbeing.

Objectives: To assess the impact of the local COVID-19 outbreak on routine child health services.

Methods: The District Health Information System data set for KwaZulu-Natal (KZN) provincial health services was accessed, and monthly child health-related data were extracted for the period January 2018 - June 2020. Read More

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December 2020

The effect of lockdown on intentional and nonintentional injury during the COVID-19 pandemic in Cape Town, South Africa: A preliminary report.

S Afr Med J 2020 12 14;111(2):110-113. Epub 2020 Dec 14.

Trauma Centre, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa; Trauma Advocacy Group, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.

Background: In response to the coronavirus pandemic, lockdown restrictions and a ban on alcohol sales were introduced in South Africa. Objectives. To investigate the impact of lockdown measures on the number of patients who visited a tertiary urban trauma centre. Read More

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December 2020

Artificial Intelligence for Classification of Soft-Tissue Masses at US.

Radiol Artif Intell 2021 Jan 2;3(1):e200125. Epub 2020 Dec 2.

Department of Radiology, Division of Musculoskeletal Radiology, NYU Langone Health, 301 E 17th St, 6th Floor, New York, NY, 10003 (B.W., C.B., R.S.A.); and Department of Musculoskeletal Imaging, Hôpital Lariboisière, Paris, France (L.P.).

Purpose: To train convolutional neural network (CNN) models to classify benign and malignant soft-tissue masses at US and to differentiate three commonly observed benign masses.

Materials And Methods: In this retrospective study, US images obtained between May 2010 and June 2019 from 419 patients (mean age, 52 years ± 18 [standard deviation]; 250 women) with histologic diagnosis confirmed at biopsy or surgical excision ( = 227) or masses that demonstrated imaging characteristics of lipoma, benign peripheral nerve sheath tumor, and vascular malformation ( = 192) were included. Images in patients with a histologic diagnosis ( = 227) were used to train and evaluate a CNN model to distinguish malignant and benign lesions. Read More

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January 2021

The State of Radiology AI: Considerations for Purchase Decisions and Current Market Offerings.

Radiol Artif Intell 2020 Nov 11;2(6):e200004. Epub 2020 Nov 11.

Department of Radiology, Medical College of Georgia at Augusta University, 1120 15th St, Augusta, GA 30912 (Y.T.); and Department of Radiology, Emory University, Atlanta, Ga (B.V., E.K., A.P., J.G., N.S., H.T.).

Purpose: To provide an overview of important factors to consider when purchasing radiology artificial intelligence (AI) software and current software offerings by type, subspecialty, and modality.

Materials And Methods: Important factors for consideration when purchasing AI software, including key decision makers, data ownership and privacy, cost structures, performance indicators, and potential return on investment are described. For the market overview, a list of radiology AI companies was aggregated from the Radiological Society of North America and the Society for Imaging Informatics in Medicine conferences (November 2016-June 2019), then narrowed to companies using deep learning for imaging analysis and diagnosis. Read More

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November 2020

F-FDG PET/CT Habitat Radiomics Predicts Outcome of Patients with Cervical Cancer Treated with Chemoradiotherapy.

Radiol Artif Intell 2020 Nov 4;2(6):e190218. Epub 2020 Nov 4.

Department of Cancer Physiology (W.M., Y.T., Y.B., R.J.G.) and Gynecologic Oncology (R.W.), H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr, Tampa, FL 33612; Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, China (Y.L., N.W.); Department of Computer Science and Engineering, University of South Florida, Tampa, Fla (L.O.H.); Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine, Beihang University, Beijing, China (J.T.); and CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, China (J.T.).

Purpose: To determine if quantitative features extracted from pretherapy fluorine 18 fluorodeoxyglucose (F-FDG) PET/CT estimate prognosis in patients with locally advanced cervical cancer treated with chemoradiotherapy.

Materials And Methods: In this retrospective study, PET/CT images and outcomes were curated from 154 patients with locally advanced cervical cancer, who underwent chemoradiotherapy from two institutions between March 2008 and June 2016, separated into independent training ( = 78; mean age, 51 years ± 13 [standard deviation]) and testing ( = 76; mean age, 50 years ± 10) cohorts. Radiomic features were extracted from PET, CT, and habitat (subregions with different metabolic characteristics) images that were derived by fusing PET and CT images. Read More

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November 2020

Robust Deep Learning-based Segmentation of Glioblastoma on Routine Clinical MRI Scans Using Sparsified Training.

Radiol Artif Intell 2020 Sep 30;2(5):e190103. Epub 2020 Sep 30.

Department of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands (R.S.E., M.v.H., M.G.W.); Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (M.V., F.B., H.V., J.C.d.M.); Neurosurgical Center Amsterdam, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (D.M.J.M., P.C.D.W.H.); Institutes of Neurology & Healthcare Engineering, University College London, London, England (F.B.); Faculty of Biology, Medicine & Health, Division of Cancer Sciences, University of Manchester and Christie NHS Trust, Manchester, England (M.v.H.); Neurosurgical Oncology Unit, Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Humanitas Research Hospital, IRCCS, Milan, Italy (L.B., M.C.N., M.R., T.S.); Department of Neurologic Surgery, University of California-San Francisco, San Francisco, Calif (M.S.B., S.H.J.); Department of Neurosurgery, Medical University Vienna, Vienna, Austria (B.K., G.W.); Department of Biomedical Imaging and Image-guided Therapy, Medical University Vienna, Vienna, Austria (J.F.); Department of Neurology & Neurosurgery, University Medical Center Utrecht, Utrecht, the Netherlands (P.A.J.T.R.); and Department of Neurologic Surgery, Hôpital Lariboisière, Paris, France (E.M.).

Purpose: To improve the robustness of deep learning-based glioblastoma segmentation in a clinical setting with sparsified datasets.

Materials And Methods: In this retrospective study, preoperative T1-weighted, T2-weighted, T2-weighted fluid-attenuated inversion recovery, and postcontrast T1-weighted MRI from 117 patients (median age, 64 years; interquartile range [IQR], 55-73 years; 76 men) included within the Multimodal Brain Tumor Image Segmentation (BraTS) dataset plus a clinical dataset (2012-2013) with similar imaging modalities of 634 patients (median age, 59 years; IQR, 49-69 years; 382 men) with glioblastoma from six hospitals were used. Expert tumor delineations on the postcontrast images were available, but for various clinical datasets, one or more sequences were missing. Read More

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September 2020

Severe aortic stenosis is associated with perioperative mortality in proximal femur fracture patients.

OTA Int 2020 Jun 5;3(2):e054. Epub 2020 May 5.

Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA.

Objectives: Evaluate the correlation between aortic stenosis and perioperative mortality in patients following surgical fixation of proximal femur fractures.

Design: Retrospectively reviewed case series.

Setting: Two Academic, Level 1 Trauma Centers. Read More

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To Text or Not to Text? That is the Question.

AMIA Annu Symp Proc 2020 25;2020:187-196. Epub 2021 Jan 25.

Columbia University, New York, NY, U.S.

Texting is ubiquitous with a text frequency of 145 billion/day worldwide. This paper provides partial results of the national demonstration project called the Missouri Quality Improvement Initiative (MOQI). MOQI goals were to reduce avoidable hospitalizations using APRNs to infuse evidence-based practices, model appropriate decisions and improve communication among workers responsible for nursing home resident care. Read More

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January 2021

Evaluation of compliance with the 2017 Canadian Paediatric Society Position Statement for the management of newborns at risk for early-onset sepsis: A retrospective cohort study.

Paediatr Child Health 2021 Jun 8;26(3):e152-e157. Epub 2020 Apr 8.

Department of Maternity Care and Pediatrics, Victoria General Hospital, Victoria, British Columbia.

Introduction: Due to the nonspecific clinical presentation, clinicians often empirically treat newborns at risk of early-onset sepsis (EOS). Recently, the Canadian Paediatric Society (CPS) published updated recommendations that promote a more judicious approach to EOS management.

Objective: To examine the compliance with the CPS statement at a tertiary perinatal site and characterize the types of deviations. Read More

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Remote triage in paediatric critical care: A Canadian provincial-wide cohort study.

Paediatr Child Health 2021 Jun 9;26(3):166-172. Epub 2020 Apr 9.

Department of Pediatrics, University of Alberta, Stollery Children's Hospital, Edmonton, Alberta.

Objective: To describe remote triage of 'potentially' critically ill or injured children in a western Canadian province and to examine the associated factors with 'missings' in vital sign items recorded in centralized telephone triage consultations.

Methods: This is a provincial-wide prospective cohort study. We included all children under 17 years of age consulted through the central transport coordination centres in Alberta from June 2016 to July 2017. Read More

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Use of Propeller Flap in the Coverage of Soft-Tissue Injury in the Lower Limb.

Rev Bras Ortop (Sao Paulo) 2021 Apr 25;56(2):192-197. Epub 2020 Sep 25.

Departamento de Ortopedia e Traumatologia, Hospital de Urgências de Goiânia Dr. Valdemiro Cruz, Goiânia, GO, Brasil.

 To evaluate the use of a propeller flap to cover soft-tissue injuries in the lower limb.  A retrospective study, with review of medical records, and a convenience sample of 14 patients operated between July 2018 and June 2019. The following clinical aspects were evaluated: sex; age group; type of injury; cause of the injury; initial diagnosis; affected location; techniques for incision and identification; surgical planning; flap design; postoperative period; result of the propeller flap; and complications. Read More

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Tourniquet Use in Arthroscopic ACL Reconstruction: A Blinded Randomized Trial.

Indian J Orthop 2021 Apr 12;55(2):384-391. Epub 2020 Sep 12.

Department of Orthopaedics, Sir Ganga Ram Hospital, Room no: 1218-A 2nd floor, Old Building, Rajinder Nagar, New Delhi, 110060 India.

Introduction: Despite knowing, that tourniquet induces ischemia and soft tissue damage surgeons still use it. The purpose of this study is to compare post operative pain and quadriceps function in patients undergoing arthroscopy assisted ACL reconstruction with tourniquet and without tourniquet.

Methods: A blinded randomized prospective trial conducted at Orthopaedic department of a tertiary institute in India from Feb 2019 to June 2019. Read More

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Association between urinary potassium excretion and blood pressure: A systematic review and meta-analysis of observational studies.

J Res Med Sci 2020 30;25:116. Epub 2020 Dec 30.

Department of Community Nutrition, Food Security Research Center, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: The evidence base regarding the association between urinary potassium and blood pressure (BP), or risk of hypertension, is inconsistent. Therefore, we sought to conduct a qualitative and quantitative literature review on the association between potassium excretion and BP.

Materials And Methods: Medline, Scopus, Web of Science, Science Direct, and Google Scholar were searched up to June 2020. Read More

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December 2020

Late, But Not Too Late? Postponement of First Birth Among Highly Educated US Women.

Eur J Popul 2021 Apr 24;37(2):371-403. Epub 2020 Nov 24.

Division of Social Sciences, NYU-Abu Dhabi, P.O. Box 129188, Abu Dhabi, United Arab Emirates.

We examine the link between the postponement of parenthood and fertility outcomes among highly educated women in the USA born in 1920-1986, using data from the CPS June Supplement 1979-2016. We argue that the postponement-low fertility nexus noted in demographic and biomedical research is especially relevant for women who pursue postgraduate education because of the potential overlap of education completion, early career stages, and family formation. The results show that women with postgraduate education differ from women with college education in terms of the timing of the first birth, childlessness, and completed fertility. Read More

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Effectiveness and Key Success Factors for Implementation of Problem-Based Learning in Debre Tabor University: A Mixed Methods Study.

Ethiop J Health Sci 2020 Sep;30(5):803-816

Human Resources Directorate, Federal Ministry of Health, Addis Ababa, Ethiopia.

Background: Problem-based learning has been adopted as a core educational strategy for education of health professionals in more than a dozen of higher education institutions in Ethiopia. Debre Tabor University College of Health Sciences (DTUCHS) is one of the adopters. However, its effectiveness has not been researched yet. Read More

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September 2020

Histopathological Changes of Placenta Associated with Maternal Anaemia in Northeast Ethiopia: A Comparative Study.

Ethiop J Health Sci 2020 Sep;30(5):777-784

Département of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia,

Background: Anaemia during pregnancy affects about half of all pregnant mothers in developing countries; it is the major causes of indirect maternal mortality. Anaemia can directly cause poor growth of fetus in utero due to inadequate oxygen flow to the placental tissue or it is indirect indicator of maternal nutritional deficiency. Mal-development of placenta is the leading cause of maternal and perinatal mortality and an important factor of fetal growth retardation. Read More

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September 2020

Evaluation of Laboratory Performance, Associated Factors and Staff Awareness Towards Achieving Turnaround Time in Tertiary Hospitals, Ethiopia.

Ethiop J Health Sci 2020 Sep;30(5):767-776

Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Background: WHO recommends that each laboratory should establish turnaround time (TAT) to monitor and evaluate performance throughout processes. The status of established TAT was not yet assessed in Ethiopian Armed Force Comprehensive Specialized Hospital. The aim of this study was to evaluate the laboratory performance and associated factors towards achieving TAT in clinical chemistry and hematology tests at Armed Force Comprehensive Specialized Hospital, Addis Ababa, Ethiopia. Read More

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September 2020

Pattern and Outcomes of Injuries among Trauma Patients in Gedeo Zone, Dilla, South Ethiopia: A 5 Years Retrospective Analysis.

Ethiop J Health Sci 2020 Sep;30(5):745-754

University of Calcutta, medical college, department of Anesthesiology, India.

Background: Injury has become a life threatening community health problem associated with significant mortality and morbidity worldwide. The aim of this study was to assess the burden of injury in Dilla University Hospital.

Methods: Institution-based retrospective cross-sectional study was conducted from January 2015 to June 2019. Read More

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September 2020