Obstet Gynecol 2021 May 6. Epub 2021 May 6.
Department of Obstetrics and Gynecology, Section of Female Pelvic Medicine and Reconstructive Surgery, MedStar Washington Hospital Center and Georgetown University School of Medicine, Washington, DC; the Department of Biostatistics, Medstar Health Research Institute, Hyattsville, Maryland; the Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Health System, Pittsburgh, Pennsylvania; the Department of Urogynecology, Brown Women & Infants Hospital of Rhode Island, Providence, Rhode Island; and the Department of Subspecialty Care for Women's Health, Cleveland Clinic, Cleveland, Ohio.
Objective: To compare 6-month safety and efficacy outcomes of fractionated CO2 laser (laser) with topical clobetasol propionate (steroid) for treatment of symptomatic vulvar lichen sclerosus.
Methods: We conducted a single-center randomized controlled trial that compared fractionated CO2 laser with steroid treatment for patients with biopsy-proven lichen sclerosus. Randomization was stratified by prior clobetasol propionate use. Read More