3,478 results match your criteria italian vaccine


A survey about the degree of information and awareness of adolescents regarding vaccination in a Province of Central Italy.

Ann Ig 2021 Jun 11. Epub 2021 Jun 11.

Department of Prevention, ASL Latina, Latina, Italy.

Background: Understanding the level of awareness in adolescents on the value of vaccination is kay to developing a proper culture of prevention to counter vaccine hesitancy and the decrease in vaccination coverages.

Study Design: The aim of the survey was to evaluate awareness, attitudes, opinions, skills and knowledge about vaccines in a group of Italian adolescents through a paper-and-pencil questionnaire.

Methods: The questionnaire was administered to adolescents who had appointments in two vaccination centers of the Public Health Authority of Latina (Latium, Italy), between August 2018 and January 2019. Read More

View Article and Full-Text PDF

Initial observations on age, gender, BMI and hypertension in antibody responses to SARS-CoV-2 BNT162b2 vaccine.

EClinicalMedicine 2021 Jun 4:100928. Epub 2021 Jun 4.

Scientific Direction, IRCCS Regina Elena National Cancer Institute, Istituti Fisioterapici Ospitalieri (IFO), Rome, Italy.

Background: Literature data suggests that age, gender and body mass index (BMI) could be associated with difference in immune responses to vaccines. The first goal of the study was to analyze the antibody titre seven days after the second dose of BNT162b2 vaccine in a group of 248 healthcare workers (HCWs). The second goal was to analyze how antibody titre changes in correlation with age, gender, BMI and hypertension. Read More

View Article and Full-Text PDF

SARS-CoV-2 complete genome sequencing from the Italian Campania region using a highly automated next generation sequencing system.

J Transl Med 2021 06 5;19(1):246. Epub 2021 Jun 5.

Cell Biology and Biotherapy Unit, Istituto Nazionale Tumori "Fondazione Giovanni Pascale", IRCCS, Via Mariano Semmola, 80131, Napoli, Italy.

Background: Since the first complete genome sequencing of SARS-CoV-2 in December 2019, more than 550,000 genomes have been submitted into the GISAID database. Sequencing of the SARS-CoV-2 genome might allow identification of variants with increased contagiousness, different clinical patterns and/or different response to vaccines. A highly automated next generation sequencing (NGS)-based method might facilitate an active genomic surveillance of the virus. Read More

View Article and Full-Text PDF

Health Communication in COVID-19 Era: Experiences from the Italian VaccinarSì Network Websites.

Int J Environ Res Public Health 2021 05 25;18(11). Epub 2021 May 25.

University Hospital of Sassari, 07100 Sassari, Italy.

In 2013, in a bid to combat Vaccine Hesitancy (VH) and provide information on vaccines by communicating with the general public and the health community (e.g., healthcare workers and public health operators), the Italian Society of Hygiene and Preventive Medicine (S. Read More

View Article and Full-Text PDF

The Gender Impact Assessment among Healthcare Workers in the SARS-CoV-2 Vaccination-An Analysis of Serological Response and Side Effects.

Vaccines (Basel) 2021 May 18;9(5). Epub 2021 May 18.

Vita-Salute San Raffaele University, 20132 Milan, Italy.

Healthcare professionals are considered to be at high risk of exposure and spread of SARS-CoV-2, and have therefore been considered a priority group in COVID-19 vaccination campaign strategies. However, it must be assumed that the immune response is influenced by numerous factors, including sex and gender. The analysis of these factors is an impact element for stratifying the population and targeting the vaccination strategy. Read More

View Article and Full-Text PDF

The Impact of Pneumococcal Conjugate Vaccine (PCV) Coverage Heterogeneities on the Changing Epidemiology of Invasive Pneumococcal Disease in Switzerland, 2005-2019.

Microorganisms 2021 May 18;9(5). Epub 2021 May 18.

Institute for Infectious Diseases, University of Bern, 3001 Bern, Switzerland.

Pneumococcal conjugate vaccines (PCVs) have lowered the incidence of invasive pneumococcal disease (IPD) worldwide. However, the influence of regional vaccine uptake differences on the changing epidemiology of IPD remains unclear. We aimed to examine the overall impact of both seven- and 13-valent PCVs (PCV7 and PCV13) on IPD in Switzerland. Read More

View Article and Full-Text PDF

Pneumococcal and Influenza Vaccination Rates and Pneumococcal Invasive Disease Rates Set Geographical and Ethnic Population Susceptibility to Serious COVID-19 Cases and Deaths.

Vaccines (Basel) 2021 May 8;9(5). Epub 2021 May 8.

Department of Physiology, 567 Wilson Road, Room 1104 Biomedical and Physical Sciences Building, Michigan State University, East Lansing, MI 48824, USA.

This study examines the relationship of pneumococcal vaccination rates, influenza, measles-mumps-rubella (MMR) diphtheria-tetanus-pertussis vaccinations (DTP), polio, Haemophilus influenzae type B (Hib), and Bacillus Calmette-Guerin (tuberculosis) vaccination rates to COVID-19 case and death rates for 51 nations that have high rates of COVID-19 testing and for which nearly complete childhood, at-risk adult and elderly pneumococcal vaccination data were available. The study is unique in a large number of nations examined, the range of vaccine controls, in testing effects of combinations of vaccinations, and in examining the relationship of COVID-19 and vaccination rates to invasive pneumococcal disease (IPD). Analysis of Italian regions and the states of the United States were also performed. Read More

View Article and Full-Text PDF

Intention to Be Vaccinated for COVID-19 among Italian Nurses during the Pandemic.

Vaccines (Basel) 2021 May 12;9(5). Epub 2021 May 12.

Department of Occupational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.

Background: While the COVID-19 pandemic has spread globally, health systems are overwhelmed by both direct and indirect mortality from other treatable conditions. COVID-19 vaccination was crucial to preventing and eliminating the disease, so vaccine development for COVID-19 was fast-tracked worldwide. Despite the fact that vaccination is commonly recognized as the most effective approach, according to the World Health Organization (WHO), vaccine hesitancy is a global health issue. Read More

View Article and Full-Text PDF

COVID-19 Vaccine: A Survey of Hesitancy in Patients with Celiac Disease.

Vaccines (Basel) 2021 May 16;9(5). Epub 2021 May 16.

Gastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20214 Milan, Italy.

(1) Background: COVID-19 vaccination campaigns offer the best hope of controlling the pandemic. However, the fast production of COVID-19 vaccines has caused concern among the general public regarding their safety and efficacy. In particular, patients with chronic illnesses, such as celiac disease (CD), may be more fearful. Read More

View Article and Full-Text PDF

The Evolving Role of Immune Checkpoint Inhibitors in Hepatocellular Carcinoma Treatment.

Vaccines (Basel) 2021 May 20;9(5). Epub 2021 May 20.

Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, 70124 Bari, Italy.

Hepatocellular carcinoma (HCC) is one of most common cancers and the fourth leading cause of death worldwide. Commonly, HCC development occurs in a liver that is severely compromised by chronic injury or inflammation. Liver transplantation, hepatic resection, radiofrequency ablation (RFA), transcatheter arterial chemoembolization (TACE), and targeted therapies based on tyrosine protein kinase inhibitors are the most common treatments. Read More

View Article and Full-Text PDF

Rate and Predictors of Hesitancy toward SARS-CoV-2 Vaccine among Type 2 Diabetic Patients: Results from an Italian Survey.

Vaccines (Basel) 2021 May 4;9(5). Epub 2021 May 4.

Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40126 Bologna, Italy.

Vaccine hesitancy (VH) has been identified as one of the major health concerns of our time by the World Health Organization. It may prove especially detrimental in the light of the ongoing SARS-CoV-2 pandemic, as vaccination campaigns still represent the primary strategy against the detrimental consequences of the pandemic. Among patients suffering from type 2 diabetes mellitus (DB), who are particularly vulnerable to COVID-19, VH might represent an even more serious threat. Read More

View Article and Full-Text PDF

Post-Marketing Active Surveillance of Adverse Reactions Following Influenza Cell-Based Quadrivalent Vaccine: An Italian Prospective Observational Study.

Vaccines (Basel) 2021 May 4;9(5). Epub 2021 May 4.

Department of Biomedical Science and Human Oncology, Aldo Moro University of Bari, 70124 Bari, Italy.

Since the influenza season 2018/19, the Italian Ministry of Health recommended a dose of cell-based quadrivalent vaccine (Flucelvax Tetra) for HCWs (healthcare workers), because this vaccine seemed more efficacious in the prevention of AH3N2 virus. Due to the lack of pre-registration data, the safety profile of this new vaccine must be investigated in post-marketing surveillance. The aim of our study is to evaluate, through a post-marketing active surveillance program developed during the 2019/20 influenza season, any Adverse Events Following Immunization (AEFIs) that happened in the 7 days after immunization with Flucelvax Tetra. Read More

View Article and Full-Text PDF

Intradermal Vaccination: A Potential Tool in the Battle Against the COVID-19 Pandemic?

Risk Manag Healthc Policy 2021 20;14:2079-2087. Epub 2021 May 20.

Primary Care Unit ASL RM 1, Rome, Italy.

This narrative review is the final output of an initiative of the SIM (Italian Society of Mesotherapy). A narrative review of scientific literature on the efficacy of fractional intradermal vaccination in comparison with full doses has been conducted for the following pathogens: influenza virus, rabies virus, poliovirus (PV), hepatitis B virus (HBV), hepatitis A virus (HAV), diphtheria-tetanus-pertussis bacterias (DTP), human papillomavirus (HPV), Japanese encephalitis virus (JE), meningococcus, varicella zoster virus (VZV) and yellow fever virus. The findings suggest that the use of the intradermal route represents a valid strategy in terms of efficacy and efficiency for influenza, rabies and HBV vaccines. Read More

View Article and Full-Text PDF

Preliminary evidence on the safety profile of BNT162b2 (): new insights from data analysis in EudraVigilance and adverse reaction reports from an Italian health facility.

Hum Vaccin Immunother 2021 May 27:1-3. Epub 2021 May 27.

Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, "Luigi Sacco" University Hospital, Università di Milano, Milan, Italy.

The first vaccine against SARS-CoV-2 made available in Italy has been BNT162b2, the two-dose mRNA-based vaccine developed by Pfizer-BioNTech. The ASST Fatebenefratelli-Sacco hospital is located in one of the areas most affected by the pandemic, and to date over 2000 healthcare professionals have been injected with both vaccine doses. We have collected all spontaneous safety reports in which BNT162b2 was designated as the possible cause. Read More

View Article and Full-Text PDF

COVID-19 vaccination in pregnant and lactating diabetic women.

Nutr Metab Cardiovasc Dis 2021 Apr 24. Epub 2021 Apr 24.

Interassociative Diabetes and Pregnancy Study Group, Italian Association of Diabetologists (AMD), Italian Society of Diabetology (SID), Rome, Italy; Department of Clinical and Experimental Medicine, Endocrinology Section, University of Catania Medical School, Catania, Italy.

Aim: To discuss available information on the opportunity for pregnant women affected by diabetes/obesity to receive COVID-19 vaccine.

Data Synthesis: Pregnant women with SARS-CoV-2 (COVID-19) infection are at high risk for severe acute respiratory syndrome and adverse outcomes. Pregnant women with severe COVID-19 present increased rates of preterm delivery (<37 gestational weeks), cesarean delivery and neonatal admissions to the intensive care unit. Read More

View Article and Full-Text PDF

[Reply to "Defining priorities, the case of of COVID-19 vaccine"].

G Ital Cardiol (Rome) 2021 06;22(6):510-511

Società Italiana di Cardiologia, Roma - Mediterranea Cardiocentro, Napoli - Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli "Federico II", Napoli *e-mail:

View Article and Full-Text PDF

[Defining priorities, the case of of COVID-19 vaccine].

Authors:
Maria Frigerio

G Ital Cardiol (Rome) 2021 Jun;22(6):509-510

Cardiologia 2-Insufficienza Cardiaca e Trapianto Dipartimento Cardiotoracovascolare DeGasperis CardioCenter ASST Grande Ospedale Metropolitano Niguarda, Milano e-mail:

View Article and Full-Text PDF

[Thrombosis and COVID-19 vaccine: much ado about nothing?]

Authors:
Vincenzo Toschi

G Ital Cardiol (Rome) 2021 Jun;22(6):448-451

Servizio di Immunoematologia e Medicina Trasfusionale e Centro Emostasi e Trombosi, ASST Santi Paolo e Carlo, Milano.

Several cases of thrombosis in unusual sites associated with thrombocytopenia have been described after vaccination with the recombinant adenoviral vector encoding the spike protein antigen of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ChAdOx1 nCov-19 (AstraZeneca) and Ad26.COV.2 (Johnson & Johnson/Janssen). Read More

View Article and Full-Text PDF

Long -term persistence of antibodies against varicella in fully immunized healthcare workers: an Italian retrospective cohort study.

BMC Infect Dis 2021 May 25;21(1):475. Epub 2021 May 25.

Department of Biomedical Science and Human Oncology, Aldo Moro University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy.

Background: Chickenpox is a highly contagious disease caused by the varicella zoster virus (VZV), and in infants, adolescents, adults, pregnant women, and the immunocompromised it can be serious. The best way to prevent chickenpox is immunization with the varicella vaccine. Protective levels of antibodies induced by the varicella vaccine decline over time, but there is currently no formal recommendation for testing anti-varicella zoster virus (VZV) IgG levels in immunized healthcare workers (HCWs). Read More

View Article and Full-Text PDF

Influenza and pneumococcal vaccinations are not associated to COVID-19 outcomes among patients admitted to a university hospital.

Vaccine 2021 06 9;39(26):3493-3497. Epub 2021 May 9.

Department of Woman and Child Health and Public Health - Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; Section of Hygiene, University Department of Life Sciences and Public Health - Università Cattolica del Sacro Cuore, Rome, Italy.

In order to reduce the burden on healthcare systems and to support differential diagnosis with COVID-19, influenza and pneumococcal vaccinations were strongly recommended during the COVID-19 pandemic, especially in vulnerable groups. However, no univocal and conclusive evidence on the relationship between influenza and pneumococcal vaccinations and COVID-19 outcomes exists. We evaluated the association between such vaccinations, COVID-19 hospitalization, intensive care unit admissions and deaths in a cohort (N = 741) of COVID-19 patients who had access to the emergency room of a large Italian University hospital between March 1, 2020 and June 1, 2020. Read More

View Article and Full-Text PDF

INfluenza Vaccine Indication During therapy with Immune checkpoint inhibitors: a multicenter prospective observational study (INVIDIa-2).

J Immunother Cancer 2021 May;9(5)

Medical Oncology Unit, Universita degli Studi di Modena e Reggio Emilia, Modena, Italy.

Background: Until now, no robust data supported the efficacy, safety and recommendation for influenza vaccination in patients with cancer receiving immune checkpoint inhibitors (ICIs).

Methods: The prospective multicenter observational INfluenza Vaccine Indication During therapy with Immune checkpoint inhibitors (INVIDIa-2) study investigated the clinical effectiveness of influenza vaccination in patients with advanced cancer receiving ICIs, enrolled in 82 Italian centers from October 2019 to January 2020. The primary endpoint was the time-adjusted incidence of influenza-like illness (ILI) until April 30, 2020. Read More

View Article and Full-Text PDF

A Survey Among Italian Physicians During COVID-19 Outbreak. Could Bacillus Calmette-Guérin Vaccine Be Effective Against SARS-CoV2?

Front Pharmacol 2021 3;12:646570. Epub 2021 May 3.

Division of Allergy and Clinical Immunology, Department of Medicine ASL Salerno, "Santa Maria Della Speranza" Hospital, Salerno, Italy.

Epidemiological studies show that BCG-vaccinated population seems to be more likely protected from COVID-19 infection, but WHO gave a stark warning on use of BCG vaccine without confirmed COVID-19 trials. The aim of the study is to evaluate whether TB vaccination, performed several years earlier, could confer protection against COVID-19. After the Ethical Committee authorization, professional orders were used to contact physicians with an online survey. Read More

View Article and Full-Text PDF

[Impact of social distancing for covid-19 on youths' physical health: a systematic review of the literature.]

Recenti Prog Med 2021 05;112(5):347-359

Dipartimento di Epidemiologia del SSR, Regione Lazio, ASL Roma1.

Background: Schools' closure during covid-19 pandemic implemented almost all over the world, together with social distances measures and lockdown to reduce transmission, could have had negative impact on youths' health.

Aim: Summarize the most relevant data from a literature systematic review on the impact on youths' physical health of the 2020 school closure and social distances measures implemented in response to covid-19 pandemic.

Methods: Authors of the original review searched on 11 international databases up to 1st September 2020 to retrieve cohort studies, cross sectional surveys, uncontrolled pre-post studies and modelling studies. Read More

View Article and Full-Text PDF

Parents' intent to vaccinate against influenza during the COVID-19 pandemic in two regions in Switzerland.

Swiss Med Wkly 2021 05 12;151:w20508. Epub 2021 May 12.

Paediatric Emergency Department, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Switzerland.

Aims Of The Study: The COVID-19 pandemic is likely to overlap with the seasonal influenza epidemic, increasing the risk of overextending the health system capacity in Switzerland. Influenza vaccine uptake has remained low in most countries, including Switzerland. The aim of the study was to determine parents’ intentions towards influenza vaccination of their children, as well as themselves, and to assess regional differences. Read More

View Article and Full-Text PDF

Urology practice during the COVID-19 vaccination campaign.

Urologia 2021 May 13:3915603211016321. Epub 2021 May 13.

Department of Urology, Federico II University of Naples, Naples, Italy.

Introduction: The current scenario of the COVID-19 pandemic is significantly different from that of the first, emergency phase. Several countries in the world are experiencing a second, or even a third, wave of contagion, while awaiting the effects of mass vaccination campaigns. The aim of this report was to provide an update of previously released recommendations on prioritization and restructuring of urological activities. Read More

View Article and Full-Text PDF

Antimeningococcal Vaccination Coverage Among Healthcare Workers in an Italian University Hospital.

Front Public Health 2021 26;9:651100. Epub 2021 Apr 26.

School of Specialization in Occupational Medicine, University of Pisa, Pisa, Italy.

Following an outbreak of meningococcal epidemic in 2015 and 2016 in Tuscany, we registered a higher demand for antimeningococcal vaccination (anti-Men ACWY) by Healthcare Workers of the University Hospital of Pisa [Azienda Ospedaliero Universitaria Pisana (AOUP)]. The purpose of this work is to analyze and discuss data on vaccination coverage resulting from this vaccination campaign. We conducted a monocentric study about anti-Men vaccination in the healthcare workers of the AOUP following the outbreak of meningococcal meningitis that occurred mainly in the population of the Tuscan provinces of Pisa, Pistoia, Prato, and Florence. Read More

View Article and Full-Text PDF

[Position paper of the Italian Society of Cardiology (SIC) on COVID-19 vaccine priority in patients with cardiovascular diseases].

G Ital Cardiol (Rome) 2021 May;22(5):363-375

Società Italiana di Cardiologia, Roma - Mediterranea Cardiocentro, Napoli - Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli "Federico II", Napoli.

In over a year, the COVID-19 pandemic caused 2.69 million deaths and 122 million infections. Social isolation and distancing measures have been the only prevention available for months. Read More

View Article and Full-Text PDF

[Anti-COVID-19 vaccination: implications for Cardiology].

G Ital Cardiol (Rome) 2021 May;22(5):359-362

Direzione Sanitaria, Azienda USL di Bologna.

View Article and Full-Text PDF