1,214 results match your criteria isolated sinusitis

Infantile orbital abscess: clinical presentation, microbiological profile, and management outcomes.

Orbit 2021 May 11:1-7. Epub 2021 May 11.

Department of Orbit, Oculoplasty, Reconstructive and Aesthetics, Chennai, India.

: Orbital abscesses in children are not uncommon. Unless managed in a timely fashion, they can potentially lead to vision-threatening as well as life-threatening complications. The objective of this study is to report the clinical and microbiological profile and management outcomes in infants presenting with orbital abscesses. Read More

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The Role of Imaging in the Preoperative Assessment of Patients with Nasal Obstruction and Septal Deviation-A Retrospective Cohort Study.

Int Arch Otorhinolaryngol 2021 Apr 23;25(2):e242-e248. Epub 2020 Jun 23.

Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

 Isolated nasal obstruction (INO) is a common complaint of multiple etiology. The preoperative evaluation of patients presenting with nasal obstruction and deviated nasal septum (DNS) does not typically include imaging. The benefits of performing computed tomography (CT) in the preoperative setting are inconclusive. Read More

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Isolated Primary Sinonasal Adenocarcinoma of the Sphenoid Sinus.

Cureus 2021 Mar 26;13(3):e14127. Epub 2021 Mar 26.

Division of Neurological Surgery, University of Missouri School of Medicine, Columbia, USA.

Isolated lesions of the sphenoid sinus, particularly malignancies, are rarely reported and exist largely within the Otolaryngology literature. Delayed diagnosis may necessitate neurosurgical involvement; therefore, neurosurgeons must be aware of the range of pathologies in this region in order to provide adequate treatment. We present an unusual case of an 89-year-old female with several weeks of worsening headaches, vision loss, and cranial neuropathies. Read More

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MicroRNA Expression in Extracellular Vesicles from Nasal Lavage Fluid in Chronic Rhinosinusitis.

Biomedicines 2021 Apr 26;9(5). Epub 2021 Apr 26.

Research Institute of Medical Science, Konkuk University School of Medicine, Seoul 05030, Korea.

Extracellular vesicles (EVs) are nanovesicles of endocytic origin released by cells and found in human bodily fluids. EVs contain both mRNA and microRNA (miRNA), which can be shuttled between cells, indicating their role in cell communication. This study investigated whether nasal secretions contain EVs and whether these EVs contain RNA. Read More

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constituent fargesin has an anti-allergic effect ORAI1 channel inhibition.

Korean J Physiol Pharmacol 2021 May;25(3):251-258

Department of Physiology, Dongguk University College of Medicine, Gyeongju 38066, Korea.

magnoliae (FM), the dry flower buds of or its related species, is a traditional herbal medicine commonly used in Asia for symptomatic relief of and treating allergic rhinitis, headache, and sinusitis. Although several studies have reported the effects of FM on store-operated calcium entry (SOCE) the ORAI1 channel, which is essential during intracellular calcium signaling cascade generation for T cell activation and mast cell degranulation, the effects of its isolated constituents on SOCE remain unidentified. Therefore, we investigated which of the five major constituents of 30% ethanoic FM (vanillic acid, tiliroside, eudesmin, magnolin, and fargesin) inhibit SOCE and their physiological effects on immune cells. Read More

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Entirely endoscopic resection of a complicated juvenile psammomatoid ossifying fibroma of the paranasal sinusitis: Case report and review of the literature.

Int J Surg Case Rep 2021 Apr 13;81:105754. Epub 2021 Mar 13.

ENT Head and Neck Surgery Department, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, 20000, Casablanca, Morocco. Electronic address:

Introduction: Juvenile ossifying fibroma (OF) is a benign fibro-osseous tumor, affecting the bones of the face. It's locally very aggressive, with a strong tendency to recur. We report a case of a juvenile psammomatoid ossifying fibroma (JPOF) complicated with exophthalmos undergoing an entirely endoscopic resection. Read More

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Twist1 sustains the apoptosis resistance in eosinophils in nasal mucosa of allergic rhinitis.

Arch Biochem Biophys 2021 May 16;702:108828. Epub 2021 Mar 16.

Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Shenzhen, China; Research Center of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China. Electronic address:

Eosinophils (Eos) are the canonical effector cells in allergic rhinitis (AR) and many inflammatory diseases. The mechanism of eosinophilia occurring in the lesion sites is not fully understood yet. Twist1 protein (Twist, in short) is an apoptosis inhibitor that also has immune regulatory functions. Read More

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Classification of Bisgaard's taxa 14 and 32 and a taxon from kestrels demonstrating satellitic growth and proposal of gen. nov., including the description of three species: sp. nov., sp. nov. and sp. nov.

Int J Syst Evol Microbiol 2019 Jun 18;71(3). Epub 2021 Mar 18.

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 4 Stigboejlen, DK-1870 Fredriksberg C, Denmark.

Avian -like organisms tentatively named taxon 14 of Bisgaard have been obtained from different lesions in birds including ducks, turkeys, pigeons, geese and peafowl. Taxon 32 of Bisgaard was first reported from lesions in pigeon hawks (). The taxon isolated from kestrels () was V-factor dependent and originally reported as like. Read More

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[A case of isolated sphenoid osteoma with suppurative sinusitis in a 15-year-old child].

Vestn Otorinolaringol 2021 ;86(1):68-71

Central State Medical Academy, Moscow, Russia.

Isolated sphenoid osteomas are very rare even in adults. There are extremely few publications on pediatric cases of sphenoid osteomas. This paper presents a case of isolated sphenoid osteoma combined with suppurative sphenoiditis in a 15-year-old patient. Read More

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Chronic Sphenoiditis With Deep Neck Space Extension: Case Report With Review of the Literature and Postulated Mechanisms for Extracranial Extension.

Ear Nose Throat J 2021 Jan 20:145561321989453. Epub 2021 Jan 20.

Department of Otorhinolaryngology, 2468Rush University Medical Center, Chicago, IL, USA.

Isolated primary sphenoid sinusitis is a rare occurrence, estimated to make up less than 3% of sinus infections. The posterior anatomic location of the sphenoid makes treatment challenging when it becomes infected. Complications involving intracranial extension to surrounding structures often result in cranial nerve deficits due to their proximity. Read More

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January 2021

Evaluation of the hepatoprotective activity of Pulicaria incisa subspecies candolleana and in silico screening of its isolated phenolics.

J Ethnopharmacol 2021 May 12;271:113767. Epub 2021 Jan 12.

Pharmacognosy Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt; Center for Drug Discovery Research and Development, Ain Shams University, Egypt. Electronic address:

Ethnopharmacological Relevance: Pulicaria incisa sub. candolleana E. Gamal-Eldin (Asteraceae) was traditionally used by Bedouins as a refreshing tea and as hypoglycemic, in gastrointestinal ailments, sinusitis and headache. Read More

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Isolated Frontal Sinusitis and Anosmia: A Novel Presentation.

Indian J Otolaryngol Head Neck Surg 2021 Jan 2:1-3. Epub 2021 Jan 2.

Head of Department, Otolaryngology Head and Neck Surgery, The Queen Elizabeth Hospital, The University of Adelaide, Adelaide, Australia.

Isolated frontal sinus disease is a rare and highly morbid condition. Although chronic frontal sinusitis has been described in literature, clinically it is quite uncommon in the absence of paranasal sinusitis and rhinitis. Here we examine a case of isolated chronic frontal sinusitis presenting with anosmia-a curious clinical manifestation. Read More

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January 2021

Surgical treatment of isolated sphenoid sinusitis - A case series and review of literature.

Int J Surg Case Rep 2021 Feb 2;79:18-23. Epub 2021 Jan 2.

Department of Ophthalmology and Otolaryngology - Head and Neck Surgery, Université Laval, Quebec City, Quebec, Canada. Electronic address:

Introduction: Isolated sphenoid opacification is a rare pathology. Unlike other sinusitis, the treatment is most often surgical. Only few studies reporting the recurrence rates with long-term follow-ups are available in the literature. Read More

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February 2021

Chronic Invasive Fungal Rhinosinusitis in Immunocompetent Patients: A Retrospective Chart Review.

Front Surg 2020 16;7:608342. Epub 2020 Dec 16.

Department of Otolaryngology, Head and Neck Surgery and Communication Sciences, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.

We report cases of Chronic Invasive Fungal Sinusitis (CIFS) in patients considered as immunocompetent at tertiary care center (King Faisal Specialist Hospital), to analyze their clinical, biological, radiological features, and management. A retrospective chart review of CIFS in immunocompetent patients. The inclusion criteria as the following: immunocompetent patients of any age with histopathological findings of CIFS. Read More

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December 2020

Microbiology of orbital cellulitis with subperiosteal abscess in children: Prevalence and characteristics of group infection.

Orbit 2021 Jan 1:1-7. Epub 2021 Jan 1.

Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.

: To evaluate the predominant pathogens and clinical course in pediatric patients with orbital cellulitis (OC) complicated by subperiosteal abscess (SPA).: This is a single-center retrospective chart review evaluating pediatric patients with OC complicated by SPA treated at a tertiary care center in the Pacific Northwest. Data were analyzed for characteristics, rates of infection, and antibiotic resistance of the predominant pathogens in pediatric patients. Read More

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January 2021

Causes of cetacean stranding and death on the Catalonian coast (western Mediterranean Sea), 2012-2019.

Dis Aquat Organ 2020 Dec 17;142:239-253. Epub 2020 Dec 17.

Departament de Sanitat i Anatomia Animals, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

The causes of cetacean stranding and death along the Catalan coast between 2012 and 2019 were systematically investigated. Necropsies and detailed pathological investigations were performed on 89 well-preserved stranded cetaceans, including 72 striped dolphins Stenella coeruleoalba, 9 Risso's dolphins Grampus griseus, 5 bottlenose dolphins Tursiops truncatus, 1 common dolphin Delphinus delphis, 1 Cuvier's beaked whale Ziphius cavirostris and 1 fin whale Balaenoptera physalus. The cause of death was determined for 89. Read More

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December 2020

Microbiome of the Middle Meatus in HIV.

West Afr J Med 2020 Dec;37(7):801-804

Gombe State University and Federal Teaching Hospital, Gombe, Nigeria.

Background: Infection with Human Immunodeficiency Virus (HIV) leads to immune dysfunction with increased risk of developing varied infections including opportunistic infections. It may be that a change in the microbial community of HIV patients could be contributory to their development of rhinosinusitis. However, the normal sinonasal microbiome in HIV is yet to be thoroughly studied. Read More

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December 2020

The clinical features of endoscopic treated isolated sphenoid sinus diseases.

J Formos Med Assoc 2020 Nov 24. Epub 2020 Nov 24.

Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

Background: Isolated sphenoid sinus disease (ISSD) is a rare clinical entity with potentially serious complications. The etiological distribution of ISSD varies among different areas and ethnicities. We aimed to investigate the clinical features of patients with endoscopic treated ISSD. Read More

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November 2020

Acute isolated sphenoid sinusitis in children: A case series and systematic review of the literature.

Int J Pediatr Otorhinolaryngol 2021 Jan 11;140:110492. Epub 2020 Nov 11.

Department of Paediatric Radiology, Royal Hospital for Children, Glasgow, United Kingdom.

Objective: This study aims to present a case series and systematic review of acute isolated sphenoid sinusitis (AISS) in children in order to better characterize clinical presentation, diagnosis, treatment, and outcomes of this condition.

Data Sources: Ovid MEDLINE, Pubmed, Embase, Cochrane Library, and Google Scholar.

Study Selection: Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Read More

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January 2021

Identification of Cytochrome b-245, beta-chain gene mutations, and clinical presentations in Iranian patients with X-linked chronic granulomatous disease.

J Clin Lab Anal 2021 Feb 23;35(2):e23637. Epub 2020 Oct 23.

Cellular and Molecular Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: X-linked chronic granulomatous disease (X-CGD) is an immunodeficiency disorder caused by defects in the gp91 subunit that leads to life-threatening infections. We aimed to identify CYBB gene mutations and study clinical phenotypes in Iranian patients with probable X-CGD.

Methods: We studied four unrelated Iranian patients with probable X-CGD and their families recruited in several years. Read More

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February 2021

An Unusual Source of Sinonasal Disease in an Immunocompromised Patient: A Case Report of the Clinical Presentation, Diagnosis, and Treatment of Acanthamoeba Rhinosinusitis.

Ear Nose Throat J 2020 Oct 23:145561320968936. Epub 2020 Oct 23.

Department of Otolaryngology-Head and Neck Surgery, Hartford Hospital, Hartford, CT, USA.

Chronic nasal crusting is a commonly encountered entity in an otolaryngology office. Progressive, extensive nasal crusting with erosion is relatively unusual, however. We present the case a 58-year-old renal transplant patient with a history of vasculitis and immunosuppression who presents with subjective headache and facial pain, nasal crusting, and isolated left ethmoid sinusitis. Read More

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October 2020

A rare case of polymicrobial chronic maxillary sinusitis due to concurrent isolation of Parvimonas micra and Fusobacterium nucleatum.

Anaerobe 2020 Dec 15;66:102284. Epub 2020 Oct 15.

Microbiology Department, Papanikolaou General Hospital, Thessaloniki, Greece.

Parvimonas micra and Fusobacterium nucleatum are commensal pathogens very rarely isolated simultaneously in clinical specimens. We report a case of chronic maxillary sinusitis caused by these two pathogens, presumably resulting from a co-existing dental infection. Read More

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December 2020

[Microbiology of chronic rhinosinusitis with different clinical phenotypes].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Sep;34(9):805-810

Department of Otolaryngology Head and Neck Surgery,Second Affiliated Hospital of Nanchang University,Nanchang,330006,China.

To observe the microbiological characteristics and clinical correlation of chronic rhinosinusitis with different clinical phenotypes. One hundred and ninety-six patients with chronic rhinosinusitis(CRS) underwent nasal endoscopic surgery, including 126 patients with Chronic rhinosinusitis with nasal polyps(CRSwNP) and 70 patients with chronic rhinosinusitis without nasal polyps(CRSsNP); 78 patients with nasal septum deviation(control group) were enrolled. The nasal discharge samples were collected before operation, and the bacteria were isolated and identified by the traditional culture method. Read More

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September 2020

Isolated Fungal Sphenoid Sinusitis After Endonasal Transsphenoidal Approach.

Ear Nose Throat J 2020 Sep 23:145561320961205. Epub 2020 Sep 23.

Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital, Goyang, South Korea.

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September 2020

Role of Dupilumab in Approved Indications of COVID-19 Patient: an Efficacy-Based Nonsystematic Critical Analysis.

SN Compr Clin Med 2020 Sep 10:1-5. Epub 2020 Sep 10.

AKT memorial college of engineering and technology, Kallakurichi, Tamil Nadu India.

With many drugs being tried in the management and treatment of COVID-19, dupilumab is one such monoclonal antibody that has come under the limelight for its possible role as an adjunct therapy in COVID-19 position. There are isolated case reports and series that document a milder course of COVID-19 infection in patients who have already been on dupilumab therapy for treatment of conditions such as atopic dermatitis and chronic rhino-sinusitis with nasal polyp. There is also an ongoing debate regarding the continuation of biologicals in the COVID patient. Read More

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September 2020

Sinister sinusitis.

Arch Dis Child Educ Pract Ed 2020 Sep 15. Epub 2020 Sep 15.

Paediatric Rheumatology, Evelina London Children's Hospital, London, UK.

Two previously well Caucasian teenage girls with no significant travel or family history were admitted with sinusitis refractory to treatment with antibiotics. Both had progressive symptoms despite broad-spectrum antibiotics and developed involvement of other systems, ultimately requiring admission to the paediatric intensive care unit (PICU). They were subsequently diagnosed with the same condition and made an excellent recovery. Read More

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September 2020

Central skull base osteomyelitis secondary to invasive aspergillus sphenoid sinusitis presenting with isolated 12th nerve palsy.

IDCases 2020 11;22:e00930. Epub 2020 Aug 11.

Emergency Medicine, Govt. Medical College, Calicut, Kerala, India.

Skull base osteomyelitis is a potentially life-threatening infection, usually seen in elderly immunocompromised patients secondary to malignant otitis externa (MOE) caused by . Central or atypical skull base osteomyelitis often poses a diagnostic challenge as they present as head-ache with or without cranial nerve palsy often without any obvious source of infection. Although the incidence of fungal skull base osteomyelitis is increasing central skull base osteomyelitis due to invasive fungal sinusitis presenting with isolated hypoglossal nerve palsy has not been reported in the literature, to our knowledge. Read More

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Spectrum of Orbital Cellulitis on Magnetic Resonance Imaging.

Cureus 2020 Aug 11;12(8):e9663. Epub 2020 Aug 11.

Radiology, Bharati Vidyapeeth Hospital, Pune, IND.

Introduction Orbital infection is an ophthalmological emergency as it can lead to blindness and intracranial spread. Imaging is needed to determine the extent of the infection, to localize an abscess, and for surgical planning. The role of magnetic resonance imaging (MRI) is well established in the evaluation of orbital pathologies, including orbital cellulitis and abscess, mainly due to its ability to evaluate early intracranial involvement. Read More

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Inferior nasal turbinate mucosa shrinkage prior to surgery under local anaesthesia.

Acta Otorrinolaringol Esp 2020 Aug 24. Epub 2020 Aug 24.

General Medical Practice, Kaiserslautern, Germany.

Introduction And Objectives: Chronic rhinitis-related complaints may result from isolated hypertrophy of the inferior nasal turbinates. If the symptoms persist despite conservative management, turbinoplasty is indicated. However, the nasal mucosa lining the inferior turbinates seems decongested immediately before the surgery performed under local anaesthesia, compared to the examination when the patients were entered for surgery. Read More

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