3 results match your criteria irradiation 45 min

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Tree-based models for survival data with competing risks.

Comput Methods Programs Biomed 2018 Jun 21;159:185-198. Epub 2018 Mar 21.

Faculty of Computer Science, Bialystok University of Technology, Wiejska 45a, Bialystok 15-351, Poland. Electronic address:

Objective: Tree-based models belong to common, assumption-free methods of data analysis. Their application in survival data is narrowed to univariate models, which partition the feature space with axis-parallel hyperplanes, meaning that each internal node involves a single feature. In this paper, I extend the idea of oblique survival tree induction for competing risks by modifying a piecewise-linear criterion function. Read More

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Realistic respiratory motion margins for external beam partial breast irradiation.

Med Phys 2015 Sep;42(9):5404-9

Department of Medical Physics, Tom Baker Cancer Centre, Calgary, Alberta T2N 4N2, Canada; Department of Physics and Astronomy, University of Calgary, Calgary, Alberta T2N 1N4, Canada; and Department of Oncology, University of Calgary, Calgary, Alberta T2N 1N4, Canada.

Purpose: Respiratory margins for partial breast irradiation (PBI) have been largely based on geometric observations, which may overestimate the margin required for dosimetric coverage. In this study, dosimetric population-based respiratory margins and margin formulas for external beam partial breast irradiation are determined.

Methods: Volunteer respiratory data and anterior-posterior (AP) dose profiles from clinical treatment plans of 28 3D conformal radiotherapy (3DCRT) PBI patient plans were used to determine population-based respiratory margins. Read More

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September 2015

Both the basal transcriptional activity of the GADD45A gene and its enhancement after ionizing irradiation are mediated by AP-1 element.

Biochim Biophys Acta 2006 Oct 30;1759(10):458-69. Epub 2006 Sep 30.

Radiation Hazards Research Group, National Institute of Radiological Sciences, 9-1, Anagawa-4-chome, Inage-ku, Chiba 263-8555, Japan.

The growth arrest and DNA damage-inducible gene 45A (GADD45A) is involved in the DNA repair, maintenance of genomic stability, cell cycle control and apoptosis, and thus plays an important role in cellular response to DNA damage. The GADD45A gene is responsive to a variety of DNA-damaging agents, including ionizing radiation (IR), methyl methanesulfonate (MMS), and ultraviolet (UV) radiation. It is generally thought that induction of the GADD45A gene after IR exposure is principally p53-dependent, requiring binding of the p53 protein to the p53-recognition sequence in the third intron. Read More

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October 2006
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