34,094 results match your criteria iron deficiency


Age of Bottle Cessation and BMI-for-Age Percentile among Children Aged Thirty-Six Months Participating in WIC.

Child Obes 2021 Sep 22. Epub 2021 Sep 22.

Department of Public Health Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA.

Children's age at bottle weaning typically ranges from 12 to 24 months. The recommended age of bottle weaning varies. The American Academy of Pediatrics recommends weaning by 12 months; The American Academy of Pediatric Dentistry recommends 12-15 months; The US Department of Agriculture recommends 18 months. Read More

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September 2021

IRON MAN interacts with BRUTUS to maintain iron homeostasis in .

Proc Natl Acad Sci U S A 2021 Sep;118(39)

CAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Xishuangbanna Tropical Botanical Garden, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Kunming, Yunnan 650223, China;

IRON MAN (IMA) peptides, a family of small peptides, control iron (Fe) transport in plants, but their roles in Fe signaling remain unclear. BRUTUS (BTS) is a potential Fe sensor that negatively regulates Fe homeostasis by promoting the ubiquitin-mediated degradation of bHLH105 and bHLH115, two positive regulators of the Fe deficiency response. Here, we show that IMA peptides interact with BTS. Read More

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September 2021

Iron deficiency during the first 1,000 days of life: are we doing enough to protect the developing brain?

Proc Nutr Soc 2021 Sep 22:1-25. Epub 2021 Sep 22.

Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Ireland.

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September 2021

Itaconate regulates macrophage function through stressful iron-sulfur cluster disrupting and iron metabolism rebalancing.

FASEB J 2021 Oct;35(10):e21936

Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Tianjin, China.

Lipopolysaccharide (LPS)-stimulated macrophages express an aconitate decarboxylase (IRG1, also called ACOD1), leading to accumulation of the endogenous metabolite itaconate. However, the precise mechanisms by which elevated itaconate levels alter macrophage function are not clear. Our hypothesis is itaconate affects macrophage function through some uncertain mechanism. Read More

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October 2021

A Study to Assess the Levels of Salivary Ferritin in Iron Deficiency Anemia Subjects and Healthy Subjects.

Cureus 2021 Aug 17;13(8):e17241. Epub 2021 Aug 17.

Oral Pathology and Microbiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Introduction: Iron deficiency anemia is one of the most widespread disorders in humans. Early diagnosis of iron deficiency anemia is challenged by assessing serum ferritin levels. However, studies across the globe have concluded that ferritin is present in quantifiable amounts in saliva. Read More

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Successful Treatment of Iron Deficiency Anemia with Ferric Carboxymaltose in an Elderly Patient with Multiple Comorbidities and COVID-19.

Cureus 2021 Aug 8;13(8):e16997. Epub 2021 Aug 8.

U.O.C. di Medicina Generale e Lungodegenza, San Giovanni Bosco Hospital, ASL Napoli 1 Centro, Naples, ITA.

Anemia is frequently associated with older age and comorbidities. Also, anemia is a frequent finding in patients hospitalized for Coronavirus infectious disease 2019 (COVID-19), where it has been associated with poor outcomes. Management of anemia is thus crucial in this setting. Read More

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Socio-economic determinants of prenatal anaemia in rural communities of South-West Nigeria: a preliminary report.

Am J Blood Res 2021 15;11(4):410-416. Epub 2021 Aug 15.

Department of Haematology and Blood Transfusion, Olabisi Onabanjo University Teaching Hospital Sagamu Ogun State, Nigeria.

Background: Anaemia is common worldwide and pregnant women are one of the most vulnerable group. Although, anaemia in the general population including pregnant women is multi-factorial in aetiology, the most frequent cause in pregnancy worldwide is iron deficiency. In Nigeria, an estimated prevalence of anaemia among pregnant women ranges from 35-75%. Read More

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Bioaccessibility of minerals in combinations of biofortified foods with Fe, Zn and vitamin A.

J Food Sci Technol 2021 Nov 2;58(11):4083-4090. Epub 2021 Feb 2.

Post-Graduation Program On Food Science and Technology, Federal University of Espírito Santo (UFES), Alto Universitário s/n, Alegre, ES CEP 29500-000 Brazil.

Initiatives to improve the nutritional quality of staple foods, such as beans and cassava by bio fortification should be encouraged as an alternative to overcome the deficiencies of iron and vitamin A. The evaluation of the bio accessibility of the minerals in these foods is also important, since the composition of nutrients does not necessarily correspond to the amount absorbed and metabolized in the body. Thus, the present work aims to evaluate the bio accessibility of iron (Fe) and zinc (Zn) in the presence of β-carotene in combinations of bio fortified food sources of Fe and Zn (cowpea cooked with and without maceration: CM/CW, respectively) and β-carotene (cooked cassava and cassava flour: CC/CF, respectively). Read More

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November 2021

Comparative analysis of hematological parameters of first-time and repeat blood donors: Experience of a blood bank in southern Nigeria.

Hematol Transfus Cell Ther 2021 Sep 11. Epub 2021 Sep 11.

University of Calabar, Calabar, Nigeria.

Introduction: The safety of a blood transfusion practice is anchored on safe blood from a healthy donor, while further protecting the donor from future harm. This study aimed to evaluate the hematological parameters of blood donors in view of their donor category to aid in assessing the safety threshold in terms of donation frequency.

Methods: This study made use of the descriptive cross-sectional design. Read More

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September 2021

Assessment of analytical bias in ferritin assays and impact on functional reference limits.

Pathology 2021 Sep 15. Epub 2021 Sep 15.

Department of Laboratory Medicine, National University Hospital, Singapore.

Serum ferritin is currently the recommended laboratory test to investigate iron deficiency. There have been efforts to standardise serum ferritin assays with implementation of traceability to the World Health Organization reference standard. We evaluate the analytical bias among five widely used commercial ferritin assays in Australia. Read More

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September 2021

Iron deficiency is a risk factor for thyroid dysfunction during pregnancy: A population-based study in Belgium.

Thyroid 2021 Sep 20. Epub 2021 Sep 20.

Sciensano J. Wytsmanstraat 14, 1050 Brussels, Belgium, Brussels, Belgium;

Background: Iron deficiency affects thyroid hormones synthesis by impairing the activity of the heme-dependent thyroid peroxidase. The prevalence of iron deficiency is elevated particularly in pregnant women. This study aimed to investigate the effects of iron status on thyroid function in a nationally representative sample of mildly iodine-deficient pregnant women. Read More

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September 2021

[Iatrogenic deficits of micronutrients].

Vopr Pitan 2021 22;90(4):53-63. Epub 2021 Jul 22.

I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenov University), 119991, Moscow, Russian Federation.

Long-term use of certain drugs causes subclinical and clinically significant micronutrient deficiencies, which can affect the course of the disease, its prognosis, quality of life, and patient compliance with therapy. of the study was to single out groups of drugs, which long-term use leads to micronutrient deficiency, and to determine vitamins, minerals and trace elements, which supply can be reduced as a result of pharmacotherapy, basing on the analysis of data published in the scientific literature. . Read More

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Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism.

Kidney Int 2021 Sep 16. Epub 2021 Sep 16.

Department of Internal Medicine, Division of Endocrinology, Diabetology and Nephrology, University Hospital Tübingen, Germany; Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich at the University Tübingen, Germany; German Center for Diabetes Research (DZD) at the University Tübingen, Germany. Electronic address:

Anemia is a common complication of chronic kidney disease, affecting the quality of life of patients. Among various factors, such as iron and erythropoietin deficiency, reduced red blood cell (RBC) lifespan has been implicated in the pathogenesis of anemia. However, mechanistic data on in vivo RBC dysfunction in kidney disease are lacking. Read More

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September 2021

Sphenoparietal Sinus and Superficial Middle Cerebral Vein Thrombosis: A Case Report and Review of Literature.

Neurochirurgie 2021 Sep 16. Epub 2021 Sep 16.

Department of Neurosurgery, Hiratsuka City Hospital, 1-19-1, Minamihara, Hiratsuka, Kanagawa, Japan.

Background: Cerebral venous sinus thrombosis is rare and might be overlooked by healthcare providers. It often occurs in the transverse sinuses, superior sagittal sinus, and the vein of Trolard. Sphenoparietal sinus (SPS) and/or superficial middle cerebral vein (SMCV) thrombosis is rare and only 12 cases reported in the literature. Read More

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September 2021

Iron deficiency in JAK2 exon12 and JAK2-V617F mutated polycythemia vera.

Blood Cancer J 2021 Sep 17;11(9):154. Epub 2021 Sep 17.

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

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September 2021

Iron deficiency and biomarkers of inflammation: a 3-year prospective analysis of the DO-HEALTH trial.

Aging Clin Exp Res 2021 Sep 17. Epub 2021 Sep 17.

Department of Aging Medicine and Aging Research, University Hospital Zurich and University of Zurich, Raemistrasse 101, 8091, Zurich, Switzerland.

Background: The longitudinal association between iron deficiency and inflammatory biomarkers levels has not been fully explored among relatively healthy older adults.

Aims: To assess whether iron deficiency at baseline and at any yearly follow-up time point, with or without anemia, was associated with changes from baseline in high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) levels over 3 years.

Methods: This is a post-hoc observational analysis of DO-HEALTH, a double-blind, randomized controlled trial including 2157 European community-dwelling adults age 70+. Read More

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September 2021

Nutritional significance and therapeutic potential of Moringa oleifera: The wonder plant.

J Food Biochem 2021 Sep 17:e13933. Epub 2021 Sep 17.

Biomedical Instruments and Devices HUB, A Centre for Innovation, Design and Clinical Validation, Post Graduate Institute of Medical Education and Research, Chandigarh, Haryana, India.

Moringa oleifera is a multi-purpose plant and a comprehensive source of dietary components such as proteins, essential amino acids, vitamins, antioxidants, etc. The plant is also a rich source of other bioactive components, including flavonoids, glucosinolates, isothiocyanates, alkaloids, terpenoids, phenolics, etc. Incorporating M. Read More

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September 2021

Differential Iron Requirements for Osteoblast and Adipocyte Differentiation.

JBMR Plus 2021 Sep 26;5(9):e10529. Epub 2021 Jul 26.

Department of Medical and Molecular Genetics School of Medicine, Indiana University Indianapolis IN USA.

Bone marrow mesenchymal progenitor cells are precursors for various cell types including osteoblasts, adipocytes, and chondrocytes. The external environment and signals act to direct the pathway of differentiation. Importantly, situations such as aging and chronic kidney disease display alterations in the balance of osteoblast and adipocyte differentiation, adversely affecting bone integrity. Read More

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September 2021

The Effect of Different Timings of Delayed Cord Clamping of Term Infants on Maternal and Newborn Outcomes in Normal Vaginal Deliveries.

Cureus 2021 Aug 14;13(8):e17169. Epub 2021 Aug 14.

Obstetrics and Gynaecology, District Hospital Khurda, Khurda, IND.

Background and objective Delayed cord clamping (DCC) has proven to be an ideal approach to reduce iron deficiency anemia; however, different timings of DCC relative to the birth outcome lead to conflicting results. The present study was conducted to determine the effects of different timings of DCC on the maternal and neonatal outcomes in normal vaginal deliveries at term. Methods This was an interventional study on neonates born at term without complications to mothers with uneventful pregnancies in the labor unit of a district hospital in Odisha, India. Read More

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Micronutritional status after pylorus preserving duodenopancreatectomy: analysis of data from a randomized controlled trial.

Sci Rep 2021 Sep 16;11(1):18475. Epub 2021 Sep 16.

University Hospital for Visceral Surgery, Pius-Hospital Oldenburg, Carl Von Ossietzky University Oldenburg, Georgstr. 12, 26121, Oldenburg, Germany.

Physical frailty and nutritional malassimilation are often observed after pancreaticoduodenectomy for pancreatic cancer. But long-term data concerning the course of micronutrient status is still missing. Micronutrient status after pylorus preserving pancreaticoduodenectomy with a follow-up of 12 months was evaluated using data of a randomized controlled trial. Read More

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September 2021

Vitamin D and iron deficiencies among Saudi children and adolescents: A persistent problem in the 21 century.

Saudi J Gastroenterol 2021 Sep 14. Epub 2021 Sep 14.

Department of Biostatistics, Research Services Administration, Research center at King Fahad Medical City, Riyadh, Saudi Arabia.

Background: Although several studies have reported on the prevalence of micronutrients in Saudi Arabia, most frequently vitamin D and iron, they are either old or hospital- or primary health care center-based. The objectives of our study were to provide more updated data on the prevalence rate of micronutrients deficiency among the Saudi general pediatric population and to determine if there is an association between micronutrients deficiency and undernutrition.

Methods: The present study is part of a cross-sectional mass screening study, "Exploring the Iceberg of Celiacs in Saudi Arabia" conducted among school-aged children (6-16 years) in 2014-2015. Read More

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September 2021

The longitudinal relationship between nutritional status and anaemia among Malaysian adolescents.

Lancet Reg Health West Pac 2021 Oct 30;15:100228. Epub 2021 Jul 30.

Centre for Population Health, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Introduction: The triple burden of malnutrition characterised by stunting and wasting, overweight/obesity, and anaemia experienced by Malaysians causes severe and long-lasting damage during the period of development and rapid growth, particularly in adolescence. This study aimed to demonstrate the trend of anaemia prevalence and to determine its longitudinal association with nutritional status and lifestyle among Malaysian adolescents.

Method: The study involved secondary data analysis from the Malaysian Health and Adolescents Longitudinal Research Team (MyHeART) study. Read More

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October 2021

Treatment of adults with Eisenmenger syndrome-state of the art in the 21st century: a short overview.

Cardiovasc Diagn Ther 2021 Aug;11(4):1190-1199

Toronto Adult Congenital Heart Disease Program, Division of Cardiology, Peter Munk Cardiac Centre, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Eisenmenger syndrome (ES) develops in association with unrepaired, non-restrictive cardiac shunt lesions at the atrial, ventricular or arterial level over time. In developed countries, cardiac defects are being operated on in a timely manner, before pulmonary vascular disease develops. However, with rising immigration from underserved countries, we increasingly see patients with shunt lesions, that are not amenable for repair as pulmonary vascular disease has already established. Read More

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Myosin Heavy Chain 9 (MYH9)-Related Congenital Macrothrombocytopenia.

Cureus 2021 Aug 6;13(8):e16964. Epub 2021 Aug 6.

Oncology, Louisiana State University Health Sciences Center, Shreveport, USA.

Myosin heavy chain 9 (MYH9)-related hereditary macrothrombocytopenia is caused by mutation of the MYH9 gene encoding the heavy chain A of non-muscle myosin of class II. We present a case that emphasizes the importance of awareness of rare disorders which could potentially avoid over-investigation, especially in benign conditions. A 72-year-old Caucasian female presented for preoperative evaluation for cataract extraction. Read More

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Ectoparasitosis, a rare cause of severe iron deficiency anemia: A case report.

Ann Med Surg (Lond) 2021 Sep 6;69:102784. Epub 2021 Sep 6.

Department of Internal Medicine, Icahn School of Medicine at Mount Sinai Hospital (Elmhurst Hospital Center), USA.

Pediculosis is a common condition caused by an infestation of head and body louse (ectoparasites) and remains a public health concern. Generally, infestation presents as pruritus in children and has a benign course, but there have been a handful of cases reported in the literature describing severe iron deficiency anemia (IDA) in high-risk groups such as children, history of psychiatric disorder including depression, and low socioeconomic status. Though an uncommonly encountered etiology of anemia, the aim of this case is to increase awareness of a rare cause of severe anemia from an ectoparasites affecting a high risk population, even in developed countries. Read More

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September 2021

Temporal dynamics of mixed litter humification in an alpine treeline ecotone.

Sci Total Environ 2021 Sep 4;803:150122. Epub 2021 Sep 4.

Long-term Research Station of Alpine Ecosystems, Key laboratory of Ecological Forestry Engineering of Sichuan Province, Institute of Ecology & Forests, Sichuan Agricultural University, Chengdu 611130, China. Electronic address:

Loss of plant diversity affects mountain ecosystem properties and processes, yet few studies have focused on the impact of plant function type deficiency on mixed litter humification. To fill this knowledge gap, we conducted a 1279-day litterbag decomposition experiment with six plant functional types of foliar litter to determine the temporal dynamic characteristics of mixed litter humification in a coniferous forest (CF) and an alpine shrubland (AS). The results indicated that the humus concentrations, the net accumulations and their relative mixed effects (RME) of most types were higher in CF than those in AS at 146 days, and humus net accumulations fell to approximately -80% of the initial level within 1279 days. Read More

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September 2021

Morphological, Biochemical, and Proteomic Studies Revealed Impact of Fe and P Crosstalk on Root Development in Phaseolus vulgaris L.

Appl Biochem Biotechnol 2021 Sep 15. Epub 2021 Sep 15.

Division of Agricultural Statistics, Sher-E-Kashmir University of Agricultural Sciences & Technology of Kashmir, Shalimar, Srinagar, Jammu & Kashmir, India.

Mineral stress is one of the major abiotic stresses faced by crop plants. The present study was undertaken to investigate the impact of mineral stress (iron (Fe) and phosphorus (P)) on various morphological and biochemical responses of the shoot and root tissues and root architecture of common bean (Phaseolus vulgaris L.). Read More

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September 2021

Authors' Response to "Preoperative Intravenous Iron for Iron Deficiency is Cost-Effective Prior to Major Elective Surgery".

Pharmacoeconomics 2021 Sep 15. Epub 2021 Sep 15.

Department of Public Health and Primary Care, Faculty of Medicine, KU Leuven, Leuven, Belgium.

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September 2021

Preoperative Intravenous Iron for Iron Deficiency is Cost-Effective Prior to Major Elective Surgery.

Pharmacoeconomics 2021 Sep 15. Epub 2021 Sep 15.

Institute of Anaesthesiology, University Hospital Zurich, Zurich, Switzerland.

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September 2021

Multiple, large intra-abdominal cystic lesions and iron deficiency anaemia as the presenting symptoms of SDHD gastrointestinal stromal tumour (GIST) in a young sub-Saharan woman.

BMJ Case Rep 2021 Sep 14;14(9). Epub 2021 Sep 14.

Anatomical Pathology, Butaro Hospital, Burera, Rwanda.

We report the case of a 27-year-old female patient from sub-Saharan Africa who presented with non-specific abdominal complaints, iron deficiency anaemia and multiple, large intra-abdominal cystic lesions on imaging. The lesions appeared to be a most unusual presentation of gastrointestinal stromal tumour (GIST). GIST is a sarcomatous tumour that comprises only 0. Read More

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September 2021